2008 6 3

1998 9

IV.

2008 3 7
KN3 200mL 2008 6 20

KN3 500mL

2008 6 20

KN3 500mL 2008 6 20

KN3 200mL 1992 10 1

KN3 500mL

1968 11

KN3 500mL 1989 1

FAX

TEL
FAX

2008 6

IF
l.
MR
63
2
IF 10
3 IF
2. IF
IF

IF
3. IF
A4 9
IF IF
IF 11 1
IF

IF
4. IF
IF MR IF
IF
MR

Drug Safety Update

IF


I.
1. 1
2. 1

II.
1. 2
2. 2
3. 2
4. 2
5. 2
6. 2
7. CAS 2

III.
1. 3
2. 3
3. 3
4. 3
5. 3

IV.
1. 4
2. 4
3. 4
4. 5
5. 5
6. 5
7. 5
8. 6
9. 6
10. 6

V.
1. 7
2. 7
3. 7

VI.
1. 8
2. 8

VII.
1. 9
2. 9
3. 9
4. 9
5. 9
6. 10
7. 10

VIII. ()
1. 11
2. 11
3. 11
4. 11
5. 11
6. 12
7. 12
8. 12
9. 13
10. 13
11. 13
12. 13
13. 13
14. 13
15. 13
16. 14

IX.
1. 15
2. 15

X.
1. 16
2. 16
3. 16
4. 16
5. 16
6. 16
7. 16
8. 16
9. 16
10. 16
11. 17
12. 17
13. 17
14. 17
15. 17

XI.
1. 18
2. 18

XII.
1. 19

XIII.
1. 20

I.

I.
1.

KN 3B

KN3 2008
3 2008 6

2.

NaClK 2.7

141978

KN3

30

2008 6

II.

II.
1.
(1)

KN3

(2)

KN No.3 Injection

(3)

KN KNa

2.
(1)

C6H12O6
180.16

D-Glucopyranose

NaCl

NaCl
58.44

Sodium Chloride

KCl

KCl
74.55

Potassium
Chloride

(2)
3.

Glucose

4.
5.

Sodium Chloride

Potassium Chloride

Sodium Lactate

6.

7. CAS

KN3

30

CH3CH(OH)COONa

C3H5NaO3
Sodium Lactate
112.06

CAS50997
CAS7647145
CAS7447407
CAS72173

2008 6

III.

III.
1.

2.
(1)

(2)
(3)
(4)

(5)
(6)

pH

95

20
D
52.6
53.2

99.5

(7)

95

110

4.

3.

6.57.5
550

5.

KN3

30

2008 6

IV.

IV.
1.
(1)

500mL PLABOTTLE
200mL500mL

(2) pH 3 pH

pH
pH

5.4

4.07.5

(3)

2.
(1)

1
4

200mL

500mL

0.35 g

0.875 g

0.3

0.75 g

0.448 g

1.12 g

5.4

(2)

21.6kcal

13.5

54kcal

pH

3. 500mL PLABOTTLE

5 406
200mL
2 403
500mL
3 406

KN3

30

2008 6

IV.

4.

5
/

100mg
()

100mg

50mL 1

125mg
()

125mg

50mL 1

()

1g/10mL

50mL 624
500mL 1

pH
6

5.

pH

pH

10mL

5.40

0.1mol/L HCl (A)

pH

(A)10.0mL

1.45

3.95

(B)10.0mL

12.10

6.70

0.1mol/L NaOH (B)

7
mEq/L
Na

Cl

Lactate

50

20

50

20

6.

7.

KN3

30

2008 6

IV.

8.

9.

500mL PLABOTTLE
200mL
500mL

10.

200mL

350 mL

23.5S

500mL

700 mL

57S

KN3

30

2008 6

V.

V.
1.

2.

1 5001000mL
1 300500 mL1 80130
1 50100 mL

3.
(1)

(2)

(3)

(4)
1)

2)

3)

4)

(5)
1)

2)

KN3

30

2008 6

VI.

VI.
1.

2.
(1)

(2) 4 50mL/kg/
NaKCl 1 4

pHPco2 HCO3 5
NPN 3
1)

KN3

30

2008 6

VII.

VII.
1.
(1)

(2)

(3)

(4)

2.
(1)

(2)

(3)

(4)

(5)

(6)

3.

4.
(1)

(2)

(3)

(4)

(5)

5.
(1)

(2)
CYP450

(3)

(4)

(5)

KN3

30

2008 6

VII.

6.
(1)

(2)

(3)

7.
(1)

(2)

(3)

KN3

30

10

2008 6

VIII. ()

VIII. ()
1.

2.

1
()

2)B1

()

3.

4.

5.

()
3,4)

()

KN3

30

11

2008 6

VIII. ()

()

5)

()
6)

()

6.

7.
(1)

(2)

8.
(1)

1)

KN3

30

12

2008 6

VIII. ()

2)

141978
()

(2)

(3)

(4)

9.

10.

11.

12.

13.

14.
1 1500mL120mL

2
15.

KN3

30

13

2008 6

VIII. ()

16.

KN3

30

14

2008 6

IX.

IX.
1.

2.
(1)

LD50 mL/kg8)

686

686

4mL/min
(2)

30 6

8)

(3)

(4)

KN3

30

15

2008 6

X.

X.
1.

500mL PLABOTTLE
200mL
500mL

5
2
3

2.

3.

4.

5.

200mL 20
500mL 30 PLABOTTLE
500mL 20
PLABOTTLE

6.

3
T3

G3
3A
3
3

7.

8.

2008 3 7
22000AMX00454

9.

2008 6 20

10.

KN3

30

16

2008 6

X.

11.

1978 3 24
337
35 145 14 2

12.

13.

107 18 3 6

14.

200mL 3319513A4060
500mL PLABOTTLE
3319513A2033
500mL 3319513A3064

15.

KN3

30

17

2008 6

XI.

XI.
1.

1, 197524(5)795-807
2, 198745()664-673
3, 198745()756-765
4 , 198745()766-775
5, 199572(7)1599-1603
6, 199572(7)1633-1636
7, Medical Practice 19907()83-87
8 , 19759(9)1988-2015

2.

1,
2,
3,
4,

KN3

30

18

197618(6)697-701
197625(6)899-904
197625(7)1041-1048
197625(4)587-595

2008 6

XII.

XII.
1.

KN3

30

19

2008 6

XIII.

XIII.
1.

KA-EN 3B

KN3

30

P. T.

20

2008 6


KN3
2003 10 10 1
2006 2 20 2
2008 6 30 3

ZAK7008F07
(5477) KM