Basic Medical Sciences

BIOCHEMISTRY
Time: 75 mins

Total Marks = 122

Please use a dark pencil/pen to complete the test. Read the instructions at the beginning
carefully. This is a Sample Test Paper for practice. Please Note: There is a negative marking
of ( - ) for each incorrect response.
Multiple Choice Single Answer type, Multiple Answer Type & True or False Type
Note: Questions that include MULTIPLE options may be correct denote True or False type.

Question 1:
Which of the following statements is false?
A. nucleotides are organized circularly along the DNA double helix
B. nucleotides are organized linearly along the DNA double helix
C. the process of translation occurs outside the nucleus
D. mRNA produced during transcription occurs inside the nucleus
Question 1
Mechanism of action common to both the hormones oxytocin and
prolactinA. development of mammary glands
B. ejection of milk
C. lactation
D. contraction of the uterus
E. secretion of milk
Question 2
Excess loss of sodium in the urine results due to the deficiency ofA. vasopressin
B. aldosterone
C. ADH
D. angiotensin II
E. all of the above
Question 3
Regarding chemical structure of amino acid glutamine, the correct IUPAC
formulaA. 2,5-diamino-5-oxopentanoic acid
B. 2-aminopropanoic acid

C. 2-amino-3-sulfanylpropanoic acid
D. amino acetic acid
Question 4
Secretion of triiodothyronine (T3) by the human thyroid gland per day is
aboutA. 80 g
B. 2 g
C. 4 g
D. 8 g
Question 5
All of the following amino acids contain an aromatic R group except-

A. phenylalanine
B. tryptophan
C. tyrosine
D. histidine
Question 6
The most important local vasodilator substance for regulating local blood
flowA. histamine
B. potassium ions
C. adenosine
D. CO2
Question 7
Regarding hormone Melatonin, not true isA. is secreted by the pineal gland
B. synthesis and secretion inhibited by dark
C. synthesis and secretion inhibited by light
D. site of action>melanocytes
E. site of action> melanophores
Question 8
Hormones (chemical messengers) that act via 'ion channel' activationA. retinoic acid
B. acetylcholine
C. nitric oxide (NO)
D. platelet-derived growth factor (PDGF)
E. inhibin

Question 9
Examples of hormone that interacts by 'direct negative' feedback A. thyroxine on thyroid stimulating hormone (TSH)
B. corticotropin on corticotropin releasing hormone (CRH)
C. corticosteroid on corticotropin releasing hormone (CRH)
D. corticosteroid on corticotropin (ACTH)
Question 10
All of the following are characteristics of a substance (hormone) which is
highly protein bound exceptA. substance very little found in the urine
B. low volume of distribution < ECF
C. short biologic half-life
D. all of the above
Question11
The correct amino acid sequence structure of methionine enkaphalinA. Tyr-Gly-Gly-Phe-Leu
B. Met-Gly-Gly-Tyr-Phe
C. Phe-Gly-Gly-Tyr-Met
D. Tyr-Gly-Gly-Phe-Met
Question12
Metabolism of epinephrine is catalyzed byA. Phenylethanolamine- N-methyltransferase (PNMT)
B. catechol -O-methyltransferase (COMT)
C. Monoamine oxidase (MAO)
D. 21 -hydroxylase
Question13
Which of the following acts as a coronary vasodilator during increased
cardiac activity?
A. norepinephrine
B. angiotensin II
C. epinephrine
D. CO2
E. dopamine
Question14
In fluorescence microscopy, specific antibodies are stained withA. fluorescein isothiocyanate (FITC)
B. auramine O

C. FRAP
D. none of the above
Question 15
The function of somatomedin C isA. control of metabolic activities
B. growth in fetus
C. cartilage and skeletal growth
D. immunoregulatory
Question16
Plasma level of insulinlike growth factor (IGFII)A. 10700 ng/mL
B. 0.32 ng/mL
C. 300800 ng/mL
D. 3080 ng/mL
Question 17
Thyroid hormones (T3) act by one of the following mechanismsA. alteration of membrane permeability to ions
B. G proteincoupled receptors
C. activation of transcription and translational processes
D. activation of protein kinase by second messenger
E. activation of adenylate cyclase
Question18
Which of the following hormone is an amino acid derivative?
A. epinephrine
B. thyrotropin
C. erythropoietin
D. cortisol
E. human chorionic gonadotrophin (hCG)
Question 19
The function of somatostatin isA. to stimulate thermogenesis
B. to stimulate the synthesis and secretion of somatomedin
C. to Inhibit release of growth hormone
D. to stimulate pancreatic acinar cells to release HCO3 and water
E. to stimulate release of growth hormone
Question 20
Lipogenesis is stimulated by hormone-

A. thyroxine
B. growth hormone
C. insulin
D. glucagon
Question21
Isolation and purification of a particular hormone requireA. Bioassay
B. differential centrifugation
C. crude extract
D. Chromatography
E. Gel electrophoresis
F. all of the above
Question 22
Hyperphosphatemia is caused byA. chronic renal insufficiency
B. hypocalcemia
C. hyperparathyroidism
D. hypoparathyroidism
Question23
Hormones that interact with intercellular nuclear receptorsA. estrogen
B. somatostatin
C. insulin
D. epinephrine
Question24
Regarding biosynthesis of eicosanoids, pick the incorrect statementA. derived from 21carbon saturated fatty acid arachidonate
B. mediate pain, inflammation, and blood clotting
C. eicosanoids are paracrine hormones
D. synthesis require enzymatic action of phospholipase A2
Question 25
Watersoluble hormones with short halflives that circulate freely in the
bloodA. cortisol
B. angiotensin II
C. thyroid hormones
D. vitamin D

E. catecholamines
Question26
One of the most sensitive immunological test for diagnosis of pregnancyA. Biological test for chorionic gonadotrophic (Aschheim & Zondek)
B. radioreceptor
C. ELISA
D. hCG radioimmunoassay (subunit)
E. agglutination of latex
Question 27
Spot the correct sequence of hormonereceptor interactionA. activation of adenylate cyclasecAMPphosphorylation of serine
moietyactivates protein kinase
B. activation of adenylate cyclasecAMPactivates protein
kinasephosphorylation of serine moiety
C. activation of adenylate cyclaseactivates protein
kinasecAMPphosphorylation of serine moiety
D. cAMPactivation of adenylate cyclasephosphorylation of serine
moietyactivates protein kinase
E. activation of adenylate cyclaseactivates protein
kinasecAMPphosphorylation of serine moiety
Question 28
Hypocalcemia can be induced by all of the following exceptA. intestinal resection
B. pseudohypoparathyroidism
C. Hypoparathyroidism
D. all of the above
Question 29
What is not true about Primary Hyperparathyroidism?
A. osteoclastic bone resorption
B. plasma alkaline phosphatase
C. calcium ion concentration
D. calcium reabsorption from the bone
Question 30
Functions of insulin includesA. inhibition of protein synthesis
B. stimulation of protein degradation
C. Activation of glycogen synthase

D. increased transport of calcium and magnesium into insulinsensitive

cells
Question31
Noncarbohydrate precursors of gluconeogenesis includes all of the
following exceptA. lactate
B. glycerol
C. aminoacids
D. FFA
Question32
The function of phorylase a phosphatase is toA. convert fructose 1,6-bisphosphate to fructose 6-phosphate
B. remove phosphoryl groups from phosphoserine
C. adds phosphoryl groups to serine or threonine
D. catalyzes the phosphorolysis of glycogen
Question 33
Hormones that promote potassium uptake by cellsA. thyroxine
B. glucagon
C. insulin
D. vasopressin
Question34
Alternative fluorescent stain for mycobacteriaA. Ziehl-Neelsen stain
B. Kinyoun stain
C. auramine-rhodamine stain
D. noneof the above
Question35
The following hormone is a peptide hormoneA. Human somatomammotropin
B. 1,25-Dihydroxycholecalciferol
C. epinephrine
D. prolactin-inhibiting factor (PIF)
Question 36
Plasma level of insulinlike growth factor I (IGF-I)
A. 10700 ng/mL

B. 100700 ng/mL
C. 70700 ng/mL
D. 300800 ng/mL
E. 30800 ng/mL
Question37
Which of the following are opiates?
A. Leu-enkephalin
B. dynorphin
C. -Endorphin
D. met-enkephalin
E. morphine
Question38
Which of the following is a basic amino acid?
A. lysine
B. tyrosine
C. glutamate
D. arginine
E. aspartate
Question39
The reaction catalyzed by kinase
A. carboxylation
B. dephosphorylation
C. phosphorylation
D. phosphorolysis
Question40
Examples of calciumphospholipiddependent protein kinasesA. Myosin light-chain kinase
B. PDGF receptor
C. Protein kinase C
D. Phosphorylase kinase
E. Insulin receptor
Question 41
Erythropoiesis is stimulated by all of the following exceptA. androgenic steroids
B. high altitude
C. estrogens
D. hypoxia
E. erythropoietin

Question42
Characteristics which do not describe steroid hormonesA. lipophilic hence enter cells directly
B. binds directly with high affinity receptor proteins associated with the
nuclear
DNA
C. interact with receptor proteins in the nucleus
D. binds to hormone response elements in the cell nucleus on the nuclear
DNA
Question 43
Hormones synthesized from tyrosine include all of the following exceptA. dopamine
B. epinephrine
C. norepinephrine
D. serotonin
Question44
Regarding metabolic activities of thyroid hormones, spot the incorrectA. lipogenesis
B. glycogenolysis
C. protein synthesis
D. gluconeogenesis
E. glucose absorption
Question 45
Amino acid that contains a thioether (S) groupA. cysteine
B. serine
C. methionine
D. valine
Question46
Signal that acts through second messenger phospholipase CA. thyrotropin releasing hormone
B. somatostatin
C. Corticotropin-releasing hormone (CRH)
D. glucagon
Question47
Examples of lipid soluble hormone-

A. parathyroid hormone
B. insulin
C. thyroid hormone
D. luteinizing hormone
Question48
Sleep-inducing and anesthetic effect is seen with large doses ofA. Dehydroepiandrosterone (DHEA)
B. estrogen
C. deoxycorticosterone
D. aldosterone
Question49
Hormones that use cAMP as their second messengerA. Gastrin-releasing peptide
B. vasopressin
C. dopamine
D. parathyroid hormone (PTH)
E. angiotensin II
Question 50
Important source of energy in fastingA. triglycerides
B. ketone bodies
C. Free fatty acids
D. acetoacetyl-CoA
E. acetyl-CoA
Question51
Hormone that inhibit the secretion of milkA. prolactin
B. oxytocin
C. progesterone
D. human chorionic somatomammotropin (hCS)
Question 52
What is not true about the actions of hormone oxytocin?
A. formation of milk
B. ejection of milk
C. causes milk secretion into the ducts
D. induce uterine contractions during labor
E. contraction of myoepithelial cells

Question 53
Which of the following hormones do not belong to glycoprotein hormone
family?
A. follicle-stimulating hormone (FSH)
B. human chorionic gonadotropin (hCG)
C. thyrotropin
D. inhibin
E. relaxin
Question54
Opioid that modulates the perception of painA. bradykinin
B. Leuenkephalin
C. morphine
D. serotonin
Question55
True about parathyroid hormone (PTH)A. decreases calcium absorption by the gut
B. increases calcium absorption by the gut
C. stimulates release of calcium from bones
D. decreases serum calcium levels
E. increases calcium excretion by the kidneys
Question 56
The enzyme also known as the 'pacemaker' of glycolysisA. glucose 6-phosphate
B. Fructose-2,6-bisphosphate
C. fructose 1,6-bisphosphatase
D. phosphofructokinase
Question57
Large protein hormones includeA. dopamine
B. thyrotropinreleasing hormone
C. luteinizing hormone
D. vasopressin
Question58
In response to increase rate of tissue metabolism of about eight times
normal, increase in skeletal blood flow is aboutA. twofold

B. threefold
C. fourfold
D. tenfold
Question59
Which of the following hormone has anti-inflammatory effects?
A. testosterone
B. epinephrine
C. cortisol
D. aldosterone
E. estrogen
Question60
Which of the following hormones do not bind to plasma proteins?
A. cortisol
B. insulin
C. somatomedin C
D. IGFII
Question61
Cortisol is mostly secreted from which layer of the adrenal cortex?
A. zona glomerulosa
B. zona reticularis
C. zona fasciculata
D. both B & C
Question62
Hormones which act with membrane-bound receptorsA. estrogen
B. vasopressin
C. progesterone
D. testosterone
Question63
Which of the following is not a Polypeptide hormone?
A. oxytocin
B. proopiomelanocortin (POMC)
C. amylin
D. ACTH
E. prolactin
Question64

Proopiomelanocortin (POMC) is the precursor molecule of all of the

following exceptA. -lipotropin (LPH)
B. corticotropin
C. -Endorphin
D. Dynorphin
Question65
Hormone or chemical messenger that utilizes serine or threonine kinase
activity to bring about changes in cell functionsA. angiotensin II
B. norepinephrine
C. atrial natriuretic peptide
D. inhibin
E. vasopressin
Question66
The signal for formation of erythropoietin isA. hypoxia
B. diseases of the kidney
C. O2 tension
D. CO2 tension
Question67
A good index of the rate of synthesis of epinephrineA. normetanephrine
B. 3-methoxy-4-hydroxyphenylglycol
C. 3,4-dihydroxymandelic acid
D. 3-methoxy-4-hydroxymandelic acid
Question 68
Aldosterone is secreted from which layer of adrenal cortex?
A. Zona fasciculata
B. both B & C
C. Zona glomerulosa
D. Zona reticularis
Question69
Which of the following is not a vasodilator substance?
A. adenosine
B. phosphate compounds
C. lactic acid

D. potassium ions
E. oxygen
Question70
Hormone specifically responsible for the biological effect of sodium
retention and potassium excretionA. aldosterone
B. dehydroepiandrosterone
C. vasopressin
D. hydrocortisone
Question71
Hormone that is a renal vasodilator which causes natriuresisA. dopamine
B. angiotensin II
C. norepinephrine
D. aldosterone
E. acetylcholine
Question72
Lvi-Lorain dwarfs have a congenital inability to synthesize significant
amount ofA. growth hormone (GH)
B. somatostatin
C. insulin-like growth factor II (IGFII)
D. somatomedin C
Question 73
Synthetic 'tumor promoter' that is a potent activator of protein-kinase C
(PKC)A. phorbol ester
B. N-acetyllphenylalanine pnitrophenyl ester
C. carboxyl esters
D. phosphate ester
Question74
Which of the following statements is false (incorrect) regarding the
enzyme of gluconeogenesis- fructose 1, 6-bisphosphatase?
Statement I: AMP inhibits fructose 1,6bisphosphatase
Statement II: citrate inhibits fructose 1,6bisphosphatase
Statement III: citrate activates fructose 1,6bisphosphatase
A. Statement I is incorrect

B. Statement II is incorrect
C. Statement III is incorrect
Question75
ADH is formed primarily in theA. neurohypophysis
B. suprachiasmatic nuclei
C. paraventricular nuclei
D. supraoptic nuclei
Question 76
Normal plasma parathyroid hormone (PTH) level is aboutA. 30-35 pg/mL
B. 10 to 55 pg/mL
C. 30-53 pg/mL
D. 10-25 pg/mL
Question77
Vitamin D3 (cholecalciferol) is manufactured fromA. plant sterols
B. lanosterol
C. lanolin
D. spermaceti oil
E. cholesterol
Question78
The morning plasma corticotropin (ACTH) concentration in a healthy
resting human beingA. 55 pg/ml
B. 25 pg/ml
C. 35 pg/ml
D. 10 pg/ml
Question79
Action of parathyroid hormone on bones and kidney includes all of the
following exceptA. inhibits bone resorption
B. causes increased excretion of phosphates
C. raise serum levels of calcium
D. mobilizes calcium from bones
E. stimulates calcium reabsorption
Question80

Hormones having both protein anabolic effect and protein catabolic effectA. androgens
B. growth hormone
C. estrogen
D. insulin
E. thyroxine
Question81
Which of the following is not correct regarding the effects of anabolic
steroids?
A. LDL
B. LDL
C. HDL
D. Blood pressure
E. muscle strength
Question82
Hormone that involved in regulation of phosphate homeostasisA. calcitonin
B. parathyroid hormone (PTH)
C. 1,25-dihydroxycholecalciferol
D. all of the above
Question 83
Probes used for locating proteins in vivoA. x-ray crystallography
B. recombinant DNA method
C. automated peptide sequences
D. monoclonal antibodies
Question 84
Aromatic amino acids includeA. threonine
B. serine
C. arginine
D. leucine
E. tryptophan
Question85
Regarding arrhenoblastoma not true is
A. produces adrenal androgens
B. embryonic rest cell tumour of the adrenal gland

C. produces ovarian androgens

D. embryonic rest cell tumour of the ovary
Question 86
Vitamin used to treat patients with hypoparathyroidismA. high doses of Vitamin A
B. high doses of Vitamin C
C. high doses of Vitamin D
D. high doses of Vitamin E
Question 87
Ferritin is found primarily in theA. bone marrow
B. blood plasma
C. kidney
D. duodenum
E. small intestine
Question 88
Besides an aromatic ring, the amino acid tryptophan also contains
A. propanoic acid
B. aminoacetic acid
C. amniobutanoic acid
D. oxobutanoic acid
Question 89
Regarding enzyme-linked immunosorbent assay (ELISA) method, not true
isA. allows detection and the quantitation of antigen
B. can be performed using monoclonal antibodies
C. enzyme of interest interacts with a colored substance to product a
colorless product
D. the presence of colored product indicates the presence of an antigen
E. require radioisotopes for assay
Question 90
Small neuropeptide hormones include which of the following?
A. insulin
B. cortisol
C. thyrotropinreleasing hormone (TRH)
D. thyroxine
E. gonadotropin-releasing hormone (GnRH)

Question 91
Hormones that interact by 'short loop' feedback mechanismA. thyroxine on TSH
B. cortisol on the hypothalamus
C. cortisol on anterior pituitary
D. corticotropin on the hypothalamus
Question 92
Regarding indirect ELISA, true isA. unbound antibodies are removed by washing following addition of
substrate
B. reaction of patient's antibodies with goat's antibodies
C. patient's antibodies bind with viral core proteins (antigens)
D. do not require radioisotopes for assay
Question 93
Proteins regulated by Ca2+and CalmodulinA. epinephrine
B. glycogen synthase
C. pyruvate kinase
D. threonine kinase
E. cAMP phosphodiesterase
Question94
JAKSTAT system operates as a signalling mechanism for hormonesA. erythropoietin
B. somatomedin C
C. thyroxine
D. leptin
E. all of the above
Question95
The rate of iodide trapping by the thyroid is influenced byA. circulating levels of T3 and T4
B. thyroid stimulating hormone (TSH)
C. thyrotropin
D. enzyme peroxidase
E. all of the above
Question 96
Which of the following statements regarding hormones is true?
Statement I : Corticosteroid hormones inhibit the release of corticotrophin

releasing hormone (CRH) by 'short loop feedback' mechanism

Statement II : Corticotrophin inhibit hypothalamic release of
corticotrophin releasing hormone (CRH) by direct negative feedback
Statement III : Corticotrophin exerts inhibitory effect on the
hypothalamus for CRH release by short-loop feedback mechanism
A. Statement I is correct
B. Statement II is correct
C. Statement III is correct
Question97
Action of hormone glucagon is mediated byA. protein kinase C
B. inositol-1,4,5-trisphosphate (IP3) and diacylglycerol (DAG)
C. adenylate cyclase
D. guanylate cyclase
Question 98
G ProteinCoupled Serpentine Receptors act as signal transducer for all of
the following exceptA. insulin
B. Cholecystokinin
C. Serotonin
D. Glucagon
E. somatostatin
Question99
The major circulating form of vitamin DA. 25hydroxyvitamin D [25(OH)D]
B. 1,25dihydroxyvitamin D [1,25(OH)2D]
C. vitamin D3 (cholecalciferol)
D. all of the above
Question100
The most plentiful catecholamine metabolite found in the urineA. normetanephrine
B. 3,4-dihydroxymandelic acid
C. 3-methoxy-4-hydroxymandelic acid
D. metanephrine
Question101
Besides TSH, Thyrotropinreleasing hormone (TRH) also stimulatesA. T3 and T4

B. Parathyroid hormone (PTH)

C. prolactin
D. Adrenocorticotropic hormone (ACTH)
E. somatostatin
Question102
Regarding Calcitonin, which of the following statements is true?
A. Promotes release of calcium from the bones
B. decreases serum calcium level
C. increases calcium absorption by the distal tubules of the kidney
D. stimulates bone resorption
E. splicing of calcitonin gene in the brain produces CGRP
Question103
The subunit of human TSH is coded by a gene on
A. chromosome 16
B. chromosome 11
C. chromosome 1
D. chromosome 6
Question 104
Who determined the amino acid sequence of insulin?
A. Banting and Best
B. Frederick Sanger
C. Alan Maxam
D. Walter Gilbert
Question105
Hyperkalemia is seen in which of the following conditions?
A. hyperaldosteronism
B. metabolic acidosis
C. -Adrenergic Stimulation
D. Conn's syndrome
E. metabolic alkalosis
Question106
Regarding the mode of actions of glucagon, all of the following are true
exceptA. deactivation of phosphorylase
B. activation of phosphorylase
C. conversion of glucose phosphate to glycogen is inhibited
D. inhibition of glycogen synthetase

Question 107
Prelabor value of oxytocin concentration in maternal plasmaA. 30 pg/ml
B. 35 pg/ml
C. 10 pg/ml
D. 25 pg/ml
Question108
The basis of the test for HIV infectionA. indirect ELISA
B. Western blotting
C. Northern blotting
D. sandwich ELISA
Question 109
The chief storage form of metabolic fuel in planktons (free-floating
microorganisms)A. waxes
B. lanolin
C. triaceylglycerols
D. cholesterol
Question110
Regarding progesterone, not true isA. sleepinducing at large doses
B. hydroxylation of progesterone at C-21 yields aldosterone
C. oxidation of C-17 angular methyl group to an acetaldehyde then yields
aldosterone
D. cortisol is synthesized from progesterone
E. contains two ketone groups
Question 111
Normal blood calcium level isA. 9.4 mg/dl
B. 15 mg/dl
C. 12 mg/dl
D. 6.4 mg/dl
E. 17.4 mg/dl
Question 112
Functional specificity of thyroid stimulating hormone (TSH) is conferred
by the-

A. subunit
B. both and subunits
C. subunit
D. subunit
Question113
The enzyme Phenylalanine hydroxylase is primarily found in theA. kidneys
B. brainstem
C. liver
D. all of the above
Question114
The perhydrocyclopentanophenanthrene ring of cholesterol (cholestane) is
composed ofA. benzene ring
B. cyclopentane ring
C. all of the above
D. cyclohexane ring
E. cycloheptane ring
Question 115
Hypokalemia is associated withA. adrenergic receptor blockers
B. Conn's syndrome
C. Addisons disease
D. metabolic acidosis
E. severe hemolysis
Question 116
Action of ACTH (corticotropin) on adipose tissuesA. stimulates uptake and storage of triglycerides
B. activates hormonesensitive lipase
C. stimulates uptake and storage of fat
D. mobilization of fats
E. inhibits hormonesensitive lipase
Question 117
Regarding composition of phosphoric acid in DNA structureA. hydrogen contributes to about 11%
B. phosporus constitues about 31%
C. nominal mass is about 91 Da
D. Polarizability is about 5.36 0.5 10-24cm3

Question 118
Which of the following hormones do not exhibit lipolytic activity?
A. glucagon
B. adrenocorticotropic hormone (ACTH)
C. norepinephrine
D. growth hormone (GH)
E. insulin
Question119
Which of the following substances is highly lipid soluble?
A. glucose
B. oxygen
C. sodium ions
D. chloride ions
Question 120
Cytosine is chemically represented asA. 4-aminopyrimidin-2(1H)-one
B. 5-methylpyrimidine-2,4(1H,3H)-dione
C. 9H-purin-6-amine
D. 2-amino-1,9-dihydro-6H-purin-6-one
Question121
Decreased metabolic clearance rate of a hormone occurs due toA. liver disease
B. renal insufficiency
C. bile duct obstruction
D. all of the above
Question122
Which of the following is a glycoprotein hormone?
A. vitamin D
B. norepinephrine
C. human chorionic gonadotropin (hCG)
D. dopamine

Answers
1 C -lactation
2 B - aldosterone
3 A - 2,5-diamino-5-oxopentanoic acid
4 C - 4 g
5 D - histidine
6 C - adenosine
7 synthesis and secretion inhibited by dark; site of action> melanocytes
8 B - acetylcholine
9 C - corticosteroid on corticotropin releasing hormone (CRH)
10 C -short biologic halflife
11 D - Tyr-Gly-Gly-Phe-Met
12 C - Monoamine oxidase (MAO)
13 C - epinephrine
14 A -fluorescein isothiocyanate (FITC)
15 C - cartilage and skeletal growth
16 C - 300800 ng/mL
17 C - activation of transcription and translational processes
18 A - epinephrine
19 C -to Inhibit release of growth hormone
20 C - insulin
21 A - Bioassay
22 chronic renal insufficiency; hypoparathyroidism
23 A -estrogen
24 A - derived from 21carbon saturated fatty acid arachidonate
25 angiotensin II; catecholamines
26 B - radioreceptor
27 B - activation of adenylate cyclasecAMPactivates protein
kinasephosphorylation of serine moiety
28 B - pseudohypoparathyroidism
29 D - calcium reabsorption from the bone
30 C - Activation of glycogen synthase
31 D -FFA
32 B - remove phosphoryl groups from phosphoserine
33 C - insulin
34 C - auramine-rhodamine stain
35 A -Human somatomammotropin
36 A - 10700 ng/mL
37 E - morphine
38 lysine; arginine
39 C -phosphorylation
40 C - Protein kinase C
41 C - estrogens
42 B - binds directly with high affinity receptor proteins associated with
the nuclear DNA

43 D - serotonin
44 lipogenesis; gluconeogenesis
45 C - methionine
46 A -thyrotropin releasing hormone
47 C - thyroid hormone
48 C - deoxycorticosterone
49 dopamine; parathyroid hormone (PTH)
50 B - ketone bodies
51 C -progesterone
52 formation of milk; causes milk secretion into the ducts
53 inhibin; relaxin
54 B - Leuenkephalin
55 increases calcium absorption by the gut; stimulates release of calcium
from bones
56 D - phosphofructokinase
57 C - luteinizing hormone
58 C - fourfold
59 C -cortisol
60 B - insulin
61 C - zona fasciculata
62 B - vasopressin
63 E - prolactin
64 D - Dynorphin
65 D - inhibin
66 A - hypoxia
67 A - normetanephrine
68 C - Zona glomerulosa
69 phosphate compounds; oxygen
70 A - aldosterone
71 A - dopamine
72 D - somatomedin C
73 A - phorbol ester
74 B - Statement II is incorrect
75 D - supraoptic nuclei
76 B - 10 to 55 pg/mL
77 C - lanolin
78 B - 25 pg/ml
79 A - inhibits bone resorption
80 E - thyroxine
81 A - LDL
82 B -parathyroid hormone (PTH)
83 D - monoclonal antibodies
84 E - tryptophan
85 produces adrenal androgens; embryonic rest cell tumour of the
adrenal gland
86 C - high doses of Vitamin D
87 C - kidney
88 A - propanoic acid

89 enzyme of interest interacts with a colored substance to product a

colorless product; require radioisotopes for assay
90 thyrotropinreleasing hormone (TRH); gonadotropin-releasing hormone
(GnRH)
91 D - corticotropin on the hypothalamus
92 A - unbound antibodies are removed by washing following addition of
substrate
93 E - cAMP phosphodiesterase
94 erythropoietin; leptin
95 B - thyroid stimulating hormone (TSH)
96 Statement III is correct
97 C - adenylate cyclase
98 A - insulin
99 A - 25hydroxyvitamin D [25(OH)D]
100 C -3-methoxy-4-hydroxymandelic acid
101 C - prolactin
102 B - decreases serum calcium level
103 D - chromosome 6
104 B -Frederick Sanger
105 B - metabolic acidosis
106 A - deactivation of phosphorylase
107 D - 25 pg/ml
108 A - indirect ELISA
109 A -waxes
110 hydroxylation of progesterone at C-21 yields aldosterone; oxidation of
C-17 angular methyl group to an acetaldehyde then yields aldosterone
111 A - 9.4 mg/dl
112 D -subunit
113 C - liver
114 cyclopentane ring; cyclohexane ring
115 B -Conn's syndrome
116 activates hormonesensitive lipase; mobilization of fats
117 phosporus constitues about 31%; Polarizability is about 5.36 0.5 1024cm3
118 E -insulin
119 B - oxygen
120 A - 4-aminopyrimidin-2(1H)-one
121 A - liver disease
122 C -human chorionic gonadotrophin (hCG)

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