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  • ABC

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    Tayyab Tahir Minhas
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    4 vues1 page

    ABC

    Transféré par

    Tayyab Tahir Minhas
    AA

    Droits d'auteur :

    © All Rights Reserved
    Téléchargez comme PDF ou lisez en ligne sur Scribd
    Signaler comme contenu inapproprié
    sur 1
    lisene, the precise populations that may choose gingko selhpresctiption may sho he chase more at risk of potential inceractions because of their use of prescription deugs aifecting hemostasis. (See further discussion later in the sections an interactions involing: antiplatelet agents and A numnber of the beneficial interactions of ginkgo listed Laer relate to its antidschemic, antioxidant, neuroprotective eure reparative, and chemoprotective effects, Typically, these inter actions involve reduction af drg-indaved tonite, saab as eplirorosicty oF neurotoxicity, Uhrougls multiple mechanisins, these provectve effects against dug toxicities most likely apply fo numerons medications other thant those For whieh preliminary evidence already exists; see doxorubicin, evcospar. ine, gentamicin, and haloperidol later. Integrative oncological appliations for ginkgo may include radiation sensitization as Well as chemoprotection.* The role of ginkgo extract in integrative oncolopical protocols isa new area of stady Pharmacol ‘There are some pharmacokinetic dats on ginkgo extracts in both animal mols ard humans, Bieavalabilay oF both the triterpene Factones and faveriol glycosides i igh, with Figures tp to eighey per sent for some ginkgolide fract nol glcosiles are rapidly absorbed, but are extsmstvely meta bolized in humans, whikt the ‘terpenoic are exerted 1 halflife of about six hours? rinchanged, with ove “There is animal and human evidence that the extract constitu: cn can crus the Hocsl-tra barccee™ 2 The pinkpo Bevo holds querciis, kaeinplvol, sad Horhamaetin are themelves substrates of P-glycoprotein (P-gp). fea on Dug Memduin anf Biahity ly sect drug: metabolizing systems had not been systematically investigated. Thikial data fkom in itso studies was sypisaly inconclusive or conilisting, but results of more recent in vivo human wiak new suggest minimal effects of the heth on oytoclirome D430 (CYPS0) activin Gurley ct al studied the

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