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  • Geneticdisorderfactpage Tylercrandell

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    Sickle cell anemia was discovered in 1910 when a dental student presented with anemia symptoms and pain crises. Under the microscope, his red blood cells appeared sickle-shaped. The disease is inherited in a recessive genotype and primarily affects those with African ancestry. It causes red blood cells to become rigid, sticky and sickle-shaped which can lead to organ damage, pain crises and early death. The average life expectancy is 42 for males and 48 for females. Treatments include pain medications, hydroxyurea therapy and childhood vaccines to help manage symptoms and prolong life.

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    Sickle cell anemia was discovered in 1910 when a dental student presented with anemia symptoms and pain crises. Under the microscope, his red blood cells appeared sickle-shaped. The disease is inherited in a recessive genotype and primarily affects those with African ancestry. It causes red blood cells to become rigid, sticky and sickle-shaped which can lead to organ damage, pain crises and early death. The average life expectancy is 42 for males and 48 for females. Treatments include pain medications, hydroxyurea therapy and childhood vaccines to help manage symptoms and prolong life.

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    8 vues1 page

    Geneticdisorderfactpage Tylercrandell

    Transféré par

    api-307472398
    Sickle cell anemia was discovered in 1910 when a dental student presented with anemia symptoms and pain crises. Under the microscope, his red blood cells appeared sickle-shaped. The disease is inherited in a recessive genotype and primarily affects those with African ancestry. It causes red blood cells to become rigid, sticky and sickle-shaped which can lead to organ damage, pain crises and early death. The average life expectancy is 42 for males and 48 for females. Treatments include pain medications, hydroxyurea therapy and childhood vaccines to help manage symptoms and prolong life.

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    © All Rights Reserved
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    Sickle cell anemia (or Sickle cell disease) Tyler Crandell

    History of Sickle cell anemia: Sickle cell anemia was founded by Dr. James B. Herrick, a
    cardiologist, when a dental student came to him with major complaints of pain and symptoms of
    anemia Herrick assigned the case to a resident. When the resident looked at the blood of the dental
    student using a microscope he found that the blood cells were shaped in the form of a sickle. Many
    of the cases that had later came to him were mainly people with the African origins. The trait is
    inherited with a homozygous recessive genotype.
    Can you find a difference between these two blood cell pictures?

    If you said that the picture to the right has crescent moon shaped blood cells and the other did not
    then you are correct, the picture with the crescent moon shaped cells has the recessive trait of
    Sickle cell anemia. This trait can be shown at birth and could be shown later in life.
    Extreme downsides to Sickle cell anemia:
    The average life expectancy for males is 42 and for females it is 48, But scientists are
    working on research to help patients live longer.
    Exercise limitations.
    May have heart failure.
    May get lung disease.
    Pain.
    Cures to Sickle cell anemia:
    Pain relieving medications.
    Hydroxyurea (taken daily, reduces frequency of painful crises).
    Childhood vaccinations.
    Citations
    ***"A Brief History of Sickle Cell Disease."
    Brief History of Sickle Cell Disease. N.p., n.d. Web. 26 Jan. 2017.***"Sickle Cell
    A
    Society." Sickle Cell Society. N.p., n.d. Web. 26 Jan. 2017.***"Learning About Sickle Cell Disease." National Human Genome
    Research Institute (NHGRI). N.p., n.d. Web. 26 Jan. 2017.***National Institutes of Health. U.S. Department of Health and Human
    Services, n.d. Web. 26 Jan. 2017.***"Exercise Limitation, Exercise Testing and Exercise Recommendations in Sickle Cell

    Anemia." Clinical Hemorheology and Microcirculation. U.S. National Library of Medicine, n.d. Web. 26 Jan. 2017.***Mayo Clinic Staff

    Print. "Sickle Cell Anemia." Treatment - Sickle Cell Anemia - Mayo Clinic. N.p., 29 Dec. 2016. Web. 26 Jan. 2017.***National
    Institutes of Health. U.S. Department of Health and Human Services, n.d. Web. 26 Jan. 2017.***

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