Name: Dela Cruz, Kristel M.

Program: BSN2y2-3

Generic Brand Classicatio Actual dose Action Rationale Side effect Nursing
name n Considerati
on
Diazepa Valium central 2 mg, 5 mg, Most of these used to Shakiness and -Monitor for
m nervous 10 mg tablets; effects are treat anxiety Unsteady walk adverse
system 1 mg/mL, 5 thought to disorders, alc unsteadiness, reactions
agent; mg/mL, 5 result from a ohol trembling, -Monitor for
benzodiazep mg/5 mL oral facilitation of withdrawal or other therapeutic
ine solution; 5 the action of symptoms, or problems with effectiveness
anticonvulsa mg/mL gamma muscle muscle .
nt; injection; 2.5 aminobutyric spasms. control or Periodic CBC
anxiolytic mg, 5 mg, 10 acid (GABA), Diazepam is coordination and liver
mg, 15 mg, 20 an inhibitory sometimes function tests
mg rectal gel neurotransmi used with during
tter in the other prolonged
central medications therapy.
nervous to treat
system. seizures.
Phenytoi Dilantin Central 50 mg/mL ; 50 Decreases used to nausea, -Monitor
n nervous mg ; 100 mg ; the control vomiting, blood
System 30 mg ; 25 Likelihood of certain type constipation; levels.
agent; mg/mL ; 200 convulsions of seizures, tremors, Assess any
anticonvulsa mg ; 300 mg ; by and to treat slurred residual
nt; sodium reducing and prevent speech, loss of seizure
hydantoin Children from abnormal seizures that balance behavior.
6 months to 6 electrical may begin or Phenytoin is
years Vmax = discharges during or coordination; incompatible
12 mg/Kg/day within the after surgery rash; with dextrose
(10-13) brain. to the brain headache; containing
Children from or nervous confusion, solutions.
7 to 16 years system. dizziness, - Flush IV
Vmax = 9 Phenytoin is nervousness; with
mg/Kg/day (8- in a class of or.sleep saline before
20) medications problems and after
Children from called (insomnia).
6 months to anticonvulsan
 16 years Km = ts. It works
4 mg/L (2-13) by
decreasing
abnormal
electrical
activity in the
brain.
Hydralazi Apresoli Antihyperte Children: 7.5 vasodilator Hydralazine headache, -Monitor
ne ne nsive, mg/kg/da that is also used anorexia, CBC,
Vasodilator y PO or works by after heart nausea, electrolytes,
200 mg/day relaxing valve vomiting, LE
PO, whichever the muscles replacement diarrhea, cell prep,
is less, or 3.5 in the blood and in the palpitations, and ANA titer
mg/kg/day IV vessels to treatment of tachycardia prior to and
or IM help them heart failure. (rapid periodically
dilate This Talk to your heartbeat), during
lowers doctor about and prolonged
blood the possible angina therapy.
pressure and risks of using pectoris
allows blood this (chest pain).
to flow more medication
easily for your
through condition.
the veins and
arteries

Penicillin Bicilllin Based upon Moderate Penicillin kills used to treat Hypersensitivi -Assess
G L-A Penicillins to severe Susceptible a wide ty patient
ability infections bacteria by variety reactions for previous
to execute Adult and specifically ofbacterial (rash, sensitivity
or child:IM inhibiting the infections. It urticaria, reaction to
destroy 600,000-1.2 transpeptidas may also be serum penicillins or
bacterium million units in e that used to sickness); cephalos
and 1 or 2 catalyzes the prevent local porins
effectivenes doses/day for final step in certain effects. -Obtain C&S
s 10 cell wall bacterial before
 (ranging biosynthesis, infections beginning
from the cross- (such drug
limited to linking of as rheumatic therapy to
extensive), peptidoglyca fever). This identify if
they n. medication is correct
can be a long-acting -treatment
classified penicillin has
into antibiotic. It been
following works by initiated
four classes. stopping the Assess for
growth of allergic
bacteria. Reactions.
Norepin Lovarter adrenergic 1 mg/mL ; primarily May cause -Monitor
ephrine enol agonist, 8mg/250 mL- alpha- headache, intake
inotropic, D5% ; mediated anxiety, and output.
vasopressor 16mg/250mL- vasoconstricti arrhythmias, Norepin
D5% ; on= bradycardia, ephrine
4mg/250mL- increased BP respiratory reduces
D5% ; & difficulty, renal
4mg/250 mL- coronary ischemic bloodflow,
NaCl 0.9% ; blood flow. injury, or which may
8mg/250mL- beta extravasation cause
NaCl 0.9% ; 16 action=inotro at the infusion decreased
mg/250 mL- poic site. urine output
NaCl 0.9% ; stimulation initially.
4mg/500 mL- and -Avoid
D5% ; dilation of contact
16mcg/mL- coronary of drug with
NaCl 0.9% arteries iron salts,
alkalies, or
oxidizing
agents.
-Protect
solution from
light. Discard
solution
 thats
discolored or
contains a
precipitate.
Metronid Flagyl Antibiotic, Patients Dose: It inhibits This Headache, -Give drug
azole Antibacterial Metronid azole nucleic antibiotic dizziness, with
, 500mg1 acid treats only ataxia, meals to
Amebicide, tab TID PO synthesis by certain vertigo, minimize GI
Antiprotozoa Minimum disrupting bacterial and incoordination, distress
l Dose: the DNA of parasitic insomnia, To treat
PO : 250mg microbial infections. It seizures, trichomoniasi
TID IV : 100mg cells will not work peripheral s,
/mL for neuropathy, give drug for
viral fatigue, 7 days
infections anorexia, instead
(such as nausea, of 2-g
common vomiting, single
cold, flu). diarrhea, GI dose Use
Using any upset, cramps only
antibiotic Dysuria, after
when it is not incontinence, T.vaginal
needed can darkening of is has been
cause it to the urine confirmed by
not work for Thrombophl wet smear
future ebitis (IV) -Tablets may
infections be
crushed for
pts.
with difficult
swallowing
-Do not
use
aluminium
needles or
hubs,
color will turn
 orange/rust
Omepraz Prilosec gastrointesti 10 mg, 20 mg, An antisecret Duodenal and CNS: -Monitor
ole nal 40 mg ory gastric ulcer. Headache, Urinalysis for
agent; capsules compound Gastroesopha dizziness, hematuria
proton that is a geal reflux fatigue. and
pump gastric acid disease GI: proteinuria.
inhibitor pump including Diarrhea, Periodic liver
inhibitor. severe abdominal function tests
Suppresses erosive pain, nausea, with
gastric acid esophagitis mild transient prolonged
secretion by (4 to 8 wk increases in use.
inhibiting the treatment). liver function -Assess GI
H+, Long-term tests. system:
K+-ATPase treatment of Urogenital: bowel sounds
enzyme pathologic Hematuria, every 8hours,
system hypersecreto proteinuria. abdomen for
[the acid ry conditions Skin:Rash pain and
(proton such as swelling,
H+) pump] in Zollinger appetite loss
the - -Assess other
parietal cells. Ellison medications
syndrome, patient may
multiple be taking for
endocrine effectiveness
adenomas, and
and interactions
systemic
mastocytosis.
Pregabali Lyrica analgesics,a 100 mg three Binds to treated with Difficult or -Monitor for
n nticonv times a day calcium antidepressa Labored weight gain,
ulsants (300 mg/day) channels in nts, various breathing peripheral
Pharmacolo in patients CNS tissues anticonvulsan shortness of edema, and
gic: with creatinine which ts, opioids, breath S&S of heart
gammaamin clearance of at regulate and tightness in failure,
obutyric least neurotransmi cannabinoids, the chest especially
acid (GABA) 60mL/min. tter but in many with
 analogues,n Begin dosing release. Does cases concurrent
onopioid at 50 mg three not treatment is thiazolidi
analgesics times a bind to opioid insufficient nedione
day (150 receptors and (e.g.,
mg/day). associated rosiglitazone)
The dose may with a range therapy.
be increased of side- -Lab tests:
to 300mg/day effects. Baseline and
within 1 week periodic
kidney
function
tests;
periodic
platelet
counts;
CPK if
rhabdom
yolysis is
suspected.
-Monitor
diabetics for
increased
incidences of
hypoglycemi
a
Furosemi Lasix electrolytic 20 mg, 40 mg, Rapid-acting blocking the CV:Postural -Observe
de and water 80 mg potent absorption of hypotension, patients
balance tablets; 10 sulfonamide sodium, dizziness with receiving
mg/mL, 40 loop chloride, and excessive parenteral
agent; loop
mg/5 mL oral diuretic and water from diuresis, acute drug
diuretic solution; 10 antihypertens the filtered hypotensive carefully;
mg/mL ive with fluid in the episodes, closely
injection pharmacologi kidney circulatory monitor BP
c effects and tubules, collapse. and vital
uses almost causing a Metabolic:Hy signs.
identical to profound povolemia, -Sudden
those of increase in dehydration, death from
ethacrynic the output of hyponatremia, cardiac arrest
acid. Exact urine hypokalemia, has been
mode of (diuresis). hypochloremia reported.
action not The onset of metabolic -Monitor BP
clearly action after alkalosis, during
defined; oral hypomagnese periods of
decreases administratio mia, diuresis and
renal n is within hypocalcemia through
vascular one hour, and (tetany), period of
resistance the diuresis hyperglycemia dosage
and may lasts about 6- , glycosuria, adjustment.
increase 8 hours. elevated BUN, -Observe
renal blood hyperuricemia older adults
flow. ;. closely
GI:Nausea, during period
vomiting, oral of brisk
and gastric diuresis.
burning, Sudden
anorexia, alteration in
diarrhea, fluid and
constipation, electrolyte
abdominal balance may
cramping, precipitate
acute significant
pancreatitis, adverse
jaundice.. reactions.
Hematologic: Report
Anemia, symptoms to
leukopenia, physician.
thrombocytop -Lab tests:
enic purpura; Obtain
agranulocytosi frequent
s blood count,
Skin:Pruritus, serum and
urticaria, urine
exfoliative electrolytes,
dermatitis, CO2, BUN,
purpura, blood sugar,
BodyWhole:I and uric acid
ncreased values during
perspiration; first few
paresthesias; months of
activation of therapy and
SLE, muscle periodically
spasms, thereafter.
weakness; Monitor for
thrombophlebi S&S of
ti hypokalemia
.
Dela Cruz, Kristine

Generic Brand Classificat Actual Nursing

Action Rationale Side effect
Name Name ion Dose Consideration
Atropine Isopto Antimuscar IV 0.5 mg to Acts by used to treat dry mouth, Monitor vital
Sulfate Atropine inic agent. 1 mg (5 - 10 selectively bradycardia blurred vision, signs
mL of the blocking all (low heart sensitivity to light, -Monitor Input &
0.1 mg/mL muscarinic rate), reduce lack of sweating, ouput especially
solution) for reponse to salivation and dizziness, in older adults
antisialagog acetylcholin bronchial nausea, and patients
ue and e. secretions loss of balance, who have had
other Selectively before hypersensitivity surgery.
antivagal depression surgery reactions (such as -Patients
effects, to 2 of CNS skin rash), and receiving
to 3 mg (20 relieves rapid heartbeat atropine via
- 30 mL of rigidity and (tachycardia). inhalation
the 0.1 tremor of sometimes
mg/mL Parkinsons manifest mild
solution) syndrome. CNS stimulation.
-Monitor infants,
small children
and older adults
for Atropine
fever
Adenosine Adenocar Antiarrhyth Injectable / slows Treating CNS:Drowsiness; Monitor for
d mic agents IV conduction certain kinds emotional signs &
solution.3m time of irregular instability; tremors symptoms of
g/dl through the heartbeat (as Genital/Urinary bronchospasm
A-V node, a System in asthma
can prescription- Vaginal pressure; patients.
 interrupt only urgency -Use a
the reentry intravenous Respiratory System hemodynamic
pathways medicine) Cough system during
through the Special Senses administration
A-V node, Blurred vision; dry of. Monitor BP &
and can mouth; ear HR
restore discomfort; metallic
normal taste;
sinus nasal congestion;
rhythm in scotomas; tongue
patients discomfort
with
paroxysmal
supraventric
ular
tachycardia
(PSVT),
including
PSVT
associated
with Wolff-
Parkinson-
White
Syndrome.
Dopamine Intropin Antiarrhyth 1 month or nerves use It works by CNS: Headache palpate
mic agents older: 1 to to improving the EENT: Mydriasis peripheral
20 communicat pumping Respiratory: pulses and
mcg/kg/min e) in the strength of Dyspnea assess
by brain. the heart and CV: arrhythmias, appearance of
continuous improves hypotension, Agina, extremities
IV infusion, blood flow to Vasoconstriction routinely during
titrated to the kidneys. GI: N&V dopamine
desired acts on Local: irritation at IV administration.
response. GABAA site. -Monitor urine
receptors, output
increasing frequently
 synaptic -Monitor Blood
inhibition. pressure, Heart
This has the rate, pulse
effect of pressure, ECG
elevating and pulmonary
seizure capillaty wedge.
threshold and
reducing the
spread of
seizure
activity from
a seizure
focus.
Phenobarb Dobutrex Anti Infants and acts on It works by Sedation and History:
ita convulsant children: GABAA depressing hypnosis are the hypersensitivity
15-20 receptors, the central principal side to barbiturates,
mg/kg IV increasing nervous effects manifest or
infused at a synaptic system. This (occasionally, they latent porphyria
rate not to inhibition. aids you in are also the Physical:
exceed 2 This has the relaxing and intended effects) of Weigth. Skin
mg/kg/min; effect of going to phenobarbital. color, lesions,
not to elevating sleep. Central nervous reflexes,
exceed seizure system effects, such orthostatic BP,
1000 threshold as adventitious
mg/dose and dizziness, nystagmu sounds, bowel
reducing s and ataxia, are sounds,
the spread also common. -Monitor
of seizure patients
activity responses blood
from a levels.
seizure
focus.
Loperamid Imodium Antidiarrhe children 2 acts on It works by Bloating Monitor
e al agent to 5 years receptors slowing the -constipation therapeutic
of age (20 along the movement of - loss of appetite effectiveness
kg or less) small bowel - stomach pain -Monitor fluid
 capsule intestine to contents (severe) with and electrolyte
decrease nausea and -Discontinue if
circular and vomiting there is no
longitudinal -Skin rash improvement
muscle after 48h of
activity theraphy.

Dobutami Doburex Inotropic IV 2.5 to 15 Acting on is used to -Bloating -Monitor

ne agent mcg/kg/min beta treat acute -constipation therapeutic
infusion receptors but - loss of appetite effectiveness
rates up to and potentially - stomach pain -Monitor fluid
40 primarily on reversible (severe) with and balance
mcg/kg/min myocardial heart failure, nausea and
have been alpha such as which vomiting
required to adrenergic occurs during -Skin rash
obtain the receptors. cardiac
desired Increase surgery or in
effect cardiac cases of
output and septic or
decrease cardiogenic
pulmonary shock, on the
wedge basis of its
pressure positive
and total inotropic
systemic action.
vascular
resistance
with
comparative
ly little or
no effect on
BP.
Lozartan Coaazar angiotensin PO 2550 acts as a is used in the CNS: Dizziness,
receptor mg in 12 potent treatment of: insomnia, Monitor BP
blockers divided vasoconstric Alport headache. GI: Diarr
doses (max: tor and Syndrome hea, - Inadequate
100 mg/d) primary -Diabetic dyspepsia. Musculos response may
vasoactive Kidney keletal: Muscle be improved by
hormone of Disease cramps, myalgia, splitting the
the renin -High Blood back or leg pain. daily dose into
angiotensin Pressure Respiratory: twice-daily
Nasal congestion, dose.
aldosterone cough, upper
system. respiratory
infection, sinusitis. -Monitor CBC,
electrolytes,
liver & kidney
function with
long-term
therapy.
Gentamici Garamyci aminoglyco Adult: Broad- used to Nausea, vomiting, -Perform C&S
n n side Obesity: spectrum prevent or stomach upset, or and renal
antibiotic Base dose aminoglycos treat a wide loss of appetite. function prior to
on lean ide variety of numbness/tingling, first dose and
body mass. antibiotic bacterial muscle twitching or periodically
Usual derived infections weakness, seizure during therapy.
duration 7 fromMicrom -Repeat C&S if
10 days. onospora improvement
1mg/kg IM purpurea. A does not occur
or IV every ction is in 35 d;
8 hours; usually reevaluate
max bacteriocida therapy.
5mg/kg/day. l. - Draw blood
For specimens for
alternative peak serum
dosing gentamicin
regimens concentration
(eg, 30 min1h after
 extended IM
intervals) administration,
see and 30 min
literature. after completion
of a 3060 min
Children:
IV infusion.
Premature
and infants
<1 week:
2.5mg/kg
every 12
hours.
Neonates:
2.5mg/kg
every 8
hours.
Others: 2
2.5mg/kg
every 8
hours.

Methrotrex Amethopt Anti- Induction: works used to treat . AzotemiaSevere. Monitor the
ate ertin, Rheumatic, 3.3 against folic certain types -Bleeding of the client taking
Folex, immunosu mg/m2/day acid of cancer of Stomach or Methotrexate
Trexall ppressant, orally or IM metabolism the breast, IntestinesSevere. for:
antimetabo (in which leads skin, head -Canker SoreSevere. -Abdominal
lite combinatio to the and neck, or -Decreased Blood pain, diarrhea or
n with inhibition of lung. Methotr PlateletsSevere. ulcerative
prednisone DNA exate is -Hole in the stomatitis.
60 mg/m2). synthesis also used to IntestineSevere. - Symptoms of
Maintenanc and cell treat severe -Infection caused by pulmonary
e (during production. psoriasis and BacteriaSevere. toxicity, which
remission): rheumatoid -Inflammation of the may manifest
15 mg/m2 arthritis. Gums and early as a dry
IM or orally MouthSevere. and
twice a nonproductive
 week. cough.
Alternate
remission
dosing: 2.5
mg/kg IV
every 14
days.

Ebede, Chisom Rita

Generic Brand Classication Actual Action Rationale Side effect Nursing

name dose Considera
tion
Penicillin Boctocill, Penicillin Neonate: Inhibit cell Used to treat Pain, -Cautiously
Oxacillin IV or IM 25 wall many different redness, in patients
sodium. mg/kg synthesis types of infections Swelling at with other
daily during caused by the inject drug
recommen microorganis bacteria such as site may allergy
ded by m staphylococcal occure, especially
manufactu multiplicatio infection. urination to
re. n bacteria less than cephalospo
resist usual, fever, rin.
Children: penicillin by chills, -Obtain
50 producing severe skin specimen
mg/kg/dos penicillinase- rash, itching for culture
e IV every enzyme that or peeling. and
6hrs. convert sensitivity
penicillin to test before
inactive first dose.
penicillin -Give 1-
acids. 2hrs or 2-
3hrs after
 meals to
prevent
gastric
irritation.
Streptom Streptom Antibiotic 1 Inhibits Used usally Black tarry -Used in
ycin ycin gram/vial CHON against stool, chest route only
sulfate synthesis tuberculosis. pain, chills, given by
strains of clumsiness, deep IM
gram cough, injection.
negative shortness of -Ensure
bacteria. breath, sore adequate
throat, hydration
painful or of patient
difficult before an
urination, during the
swollen therapy.
gum, -Monitor
vomiting. for hearing
changes.
-Report
hearing
change,
dizziness
pain at
injection
site, rash.
Penicilin Piptaz, Penicillin Piptaz It works by It is used to treat Hypersensiti -Piptaz
tazobacta Zosyn combination 2.5g IVq6 blocking the moderate to vity should not
m on, anti- 9to bacterias severe infections reactions: be added
infective, complete cell wall caused by certain rashes, to blood
antibiotic, 40 doses). growth, bacteria. pruritus and products or
beta- which kills fever albumin
lactamase the bacteria. GI: melena, hydrolysat
gastritis es and
CNS: should not
headache, be mixed
malaise, with other
Hepatic drugs in a
effects: syringe or
Kidney infusion
problem bottle due
Renal to possible
effects: problems
Increase in with
serum compatibili
concentratio ty.
n of -Use piptaz
creatinine immediatel
and blood y after
urea constipatio
nitrogen n.
should be -Discard
observed. properly
any
unused
portion
after
24hrs. if
stored at
room
temperatur
e (20-25
degree
 Celsius.)
Ciprofloxa Ciloxan, Antibacterial Not Bactericidal; -For the treatment CNS: Allergy to
cin Cipro fluoroquinolo recommen interferes of infection headache, ciprofloxaci
Cipro HC, ne ded with DNA caused by dizziness, n,
Otic, replication in susceptible gram- insomnia, norfloxacin
Cipro XR susceptible negative bacteria. fatigue, , or other
bacteria Otic: treatment of somnolence, quinolones
preventing acute otitis depression, renal
cell externa blurred impairmen
production. -Lower respiratory vision, t; seizure;
infection. hallucination lactation.
, ataxia,
nightmare.
CV:
arrhythmias,
hypotension,
angina.
EENT: dry
eye, eye
pain,
keratopathy
GI: N&V, dry
mouth,
diarrhea,
abdominal
pain.
GU: renal
failure.
Verapamil Verelan Antianginal <1yr-initial Inhibits the Angina pectoris Dizziness,ve History:
Antiarrhythm dose: 0.1- movement of due to coronary rtigo, Allergy to
ic 0.2mg/kg calcium ions artery spasm emotional verapamil;
Antihyperten 1-15yrs across the Effort- associated depression, sicl sinus
sive initial membranes angina chronic sleepness, syndrome;
Calcium dose: 0.1- of cardiac stable angina, headache, heart
Channel 0.3. and arterial unstable peripheral block;
bocker. Do not muscle cells. crescendo, edema, IHSS.
exceed preinfarction hypotension, Cardiogeni
5mg angina essential arrhythmias, c shock
repeat hypertension bradycardia. severe
above Parenteral: AV heart CHF;
dose 30 temporary control block, hypotensio
mins after of rapid nausea, n; impaired
initial dose ventricular rate in constipation, hepatic or
if response atrial flutter or muscle renal
is not atrial fibrillation. fatigue, function;
adequate. diaphrosesis pregnancy,
Repeat , rash. lactation.
dose Physical:
should not Skin color,
exceed 10 edema;
mg. orientation
, reflexes;
P, BP,
baseline
ECG,
peripheral
perfusion,
auscultatio
n; R
adventitiou
s sound;
liver
evaluation,
 norm
ouput,
LFTs, renal
function,
tests, urina
Vancomy Vancocin, Antibiotic 40mg/kg/d Bactericidal; It works by killing Increased Allergy to
cin vancoled ay PO in inhibits cells bacteria in the diarrhea vancomyci
three or wall intestine. that is n, hearing
four synthesis of watery or loss, renal
divided suscepltible bloody; impairmen
doses for organisms hearing loss, t,
7- causing cell ringing in pregnancy
100days. death. your ears; lactation.
10mg/kg/d kidney
ose IV problems-
every swelling,
6hrs. rapid weight
gain, pain in
your side or
lowe back,
little or no
urinating; or
low
potassium-
confusion,
uneven
heart rate,
extreme
thrist,
increased
urination,
 leg
discomfort,
muscle
weekness or
limp feeling.
Nausea or
stomach
pain.
Azithrom Zithroma Macrolide Otitis Bacteriostati Treatment for Diarrhea, Hypertensi
ycin x, max antibiotic media: c or lower respiratiory nausea, ve to
10mg/kg bactericidal infection, otitis vomting, azithromyc
PO as a in media, tonsillitis, abdominal in or any
single susceptible pneumonia, pain macrolide
dose, then bacteria bronchitis, antibiotic,
5mg/kg on laryngitis, renal
days 2- sinusitis, impairmen
5hrs or uncomplicated t, GI
30mg/kg skin infection. output.
PO as a
single
dose.
Communit
y acquired
pneumoni
a: 10
mg/kg PO
as a single
dose on
the 1st day
the
5mg/kg PO
 on days 2-
5.
Epinephri adrenalin Alpha Epinephrin Naturally Treatment and SpecSenses: Monitor BP,
ne e adrenergic e occurring prophylaxis of Nasal pulse,
agaonist, injection: neurotransmi cardiac arrest burning or respiration
antiasthmati 1:1000 tter, the and attacks of stinging, s, and
c, beta 1 & solution, effect of dryness of urinary
transitory AV
beta 2 children: which are nasal output and
heart blocks
adrenergic 0.01mg/kg mediated by mucosa, observe
agonist, SC for 4 alpha or beta with syncopal sneezing, patient
bronchodilat hrs in a receptors in seizures rebound closely
ors, cardiac single target (Strokes-Adams congestion. following
stimulant, dose. organs. syndrome) Transient IV
mydriatic, Infants: Constricts stinging or administrat
nasal 0.05mg SC bronchial burning of ion.
decongestan for initial arterioles and eyes, -
t, dose, inhibits lacrimation, Epinephrin
sympathomi repeat brow ache, e may
histamine
metic every 20- headache, widen
release, thus
vasopressor. 3o mins as rebound pulse
reducing
needed. conjunctival pressure. If
Neonates: congestion and hyperemia, disturbanc
0.01mg/kg edema and allergy, es in
SC. increasing tidal iritis; with cardiac
volume and vital prolonged rhythm
capacity. use: occur,
melanin-like withhold
deposits on epinephrin
lids, e and
conjunctiva, notify
and cornea; physician
 corneal immediatel
edema; loss y.
of lashes. -Check BP
repeatedly
when
epinephrin
e is
administer
ed IV
during first
5 min, then
q35min
until
stabilized.
-Monitor
blood
glucose &
HbA1c for
loss of
glycemic
control if
diabetic.
furosemid Lasix, Diuretics Infants Furosemide Furosemide is -Observe
e Fumide, and is a loop used to treat fluid -ringing in patients
Furomide Children: diuretic retention (edema) your ears, receiving
Oral: 2 (water pill) in people hearing loss; parenteral
mg/kg that prevents with congestive drug
once daily; your body heart failure, liver confusion, carefully;
if from disease, or a drowsiness, closely
ineffective absorbing kidney disorder problems monitor BP
, may too much such as nephrotic with and vital
memory or
increase in salt. This syndrome. signs.
increment allows the Furosemide is also speech; -Monitor
s of 1 to 2 salt to used to treat high BP during
mg/kg/dos instead be blood jaundice periods of
e every 6 passed in pressure (hyperte (dark urine, diuresis
to 8 hours; your urine. nsion). yellowing of and
not to the skin or through
exceed 6 eyes); period of
mg/kg/dos dosage
e. In most severe pain adjustment
cases, it is in your .
not upper -Lab tests:
necessary stomach Obtain
to exceed spreading to frequent
individual your back; blood
doses of 4 count,
mg/kg or a nausea, serum and
dosing vomiting, urine
frequency loss of electrolyte
of once or appetite, s, CO2,
twice sweet or BUN, blood
daily. musty sugar, and
IM or IV: 1 breath odor; uric acid
to 2 values
mg/kg/dos pale skin, during first
e every 6 easy few
to 12 bruising or months of
hours bleeding; therapy
Continuou and
s infusion: -sudden periodically
0.05 weakness or thereafter.
ill feeling,
 mg/kg/hou -Monitor
r; titrate fever, chills, for S&S of
dosage to sore throat; hypokalem
clinical ia.
effect

Garcia, Bryan Kenneth

Generic Brand Classificat Actual Action Rationale Side Effect Nursing

Name Name ion dose Consideration
baclofen Lioresal AUTONOMI Children: relaxes To provide Transient -Supervise
C NERVOUS Not skeletal symptomatic drowsiness, ambulation.
SYSTEM recommend muscles, the relief of painful confusion, Initially, the
AGENT; CE ed. muscles that spasms in dizziness, loss of
NTRAL- move the multiple weakness, spasticity
ACTING skeleton sclerosis and fatigue, induced by
SKELETAL (and also in the headache, baclofen may
MUSCLE called management hypotension, affect patient's
RELAXAN striated of detrusor nausea, ability to stand
muscle) sphincter increased or walk.
dyssynergia in urinary -Lab tests:
spinal cord frequency; baseline and
injury or seizures and periodic BP,
disease. hallucination weight, blood
s on abrupt sugar, hepatic
withdrawal. function tests,
and urine.
-Monitor for
adverse
neuropsychiatri
c or
genitourinary
symptoms that
resemble those
of the
underlying
disease. Assess
them carefully
and report to
the physician.
Observe
carefully for
side effects:
mental
confusion,
depression,
hallucinations.
Older adults are
especially
sensitive to this
 drug.
-Monitor
patients with
epilepsy closely
for possible loss
of seizure
control.
Calcitriol calcijex,ro HORMONES Capsules : Stimulates Management CNS:
caltrol,Ve AND 0.25 mcg, calcium of headache, Lab tests:
ctical SYNTHETIC 0.5 mcg absorption hypocalcemia somnolence, Determine
SUBSTITUT Injection: 1 from the GI in patients weakness, baseline and
ES; VITAMI mcg/ml, tract and undergoing irritability periodic levels
ND 2mcg/ml promotes chronic renal CV:hypertens of serum
ANALOG Oral movement dialysis and in ion, calcium,
solution : of calcium patients with arrhythmias phosphorus,
1mcg/ml from bone to hypoparathyro EENT: magnesium,
topical:,3m blood idism or Conjunctiviti alkaline
cg/g pseudohypopa s,photopobia phosphatase,
rathyroidism. ,Rhinorhea creatinine;
GI: nausea, measure
Vomiting, urinary calcium
constipation, and phosphorus
polydipsia,pa levels q24h.
ncreatitis,
metallic Effectiveness of
taste,dry therapy depeds
mouth, on an adequate
anorexia
GU: Polyuria, daily intake of
nocturia, calcium and
nephrocalcin phosphate. The
physician may
osis,
hypercalciuri prescribe a
a calcium
Metabolic: supplement on
weight loss an as-needed
skin: basis.
Pruritus, skin
discomfort at Monitor for
application hypercalcemia
area, (see Signs &
psoriasis Symptoms,
Other: Appendix F).
Hyperthermi During dosage
a, decreased adjustment
libido period, monitor
serum calcium
levels
particularly
twice weekly to
avoid
hypercalcemia.I
f hypercalcemia
develops, with
ld calcitriol and
calcium
supplements
and notify
physician.
Drugs may be
reinitiated
when serum
 calcium returns
to normal

Calcium Fluid and FLUID AND Children: Rapid-acting Relief of GI: Constipa
carbonate electrolyt ELECTROLY Not antacid with transient tion or Note number
e balance TIC recommend high symptoms of laxative and consistency
agent,repl BALANCE ed. neutralizing hyperacidity effect, acid of stools. If
acement AGENT; RE capacity and as in acid rebound, constipation is
solution, PLACEMEN relatively indigestion, nausea, a problem,
antacid T prolonged heartburn, eructation, f physician may
SOLUTION; duration of peptic atulence, vo prescribe
ANTACID action. esophagitis, miting, fecal alternate or
Decreases and hiatal concretions. combination
gastric hernia. Also Metabolic: therapy witha
acidity, used as Hypercalcem magnesium
thereby calcium ia with antacid or
inhibiting supplement alkalosis, advise patient
proteolytic when calcium metastatic to take a
action of intake may be calcinosis, laxative or stool
pepsin on inadequate hypercalciuri softener as
gastric and in a, necessary.
mucosa. treatment of hypomagnes
Also mild calcium emia, Lab tests:
increases deficiency hypophospha Determine
lower states. Control temia (when serum and
esophageal of phosphate urine calcium
sphincter hyperphosphat intake is weekly in
tone. emia in low). patients
Although chronic renal CNS: Mood receiving
classified as failure and mental prolonged
 a (calcium changes. Ur
nonsystemic acetate). ogenital: Po therapy and in
antacid, a lyuria, renal patients with
slight to calculi. renal
moderate dysfunction.
alkalosis
usually Record
develops amelioration of
with symptoms of
prolonged hypocalcemia
therapy. Acid (see Signs &
rebound, Symptoms,
which may Appendix F)
follow even
low doses, is Observe for
thought to S&S of
be caused hypercalcemia
by release of in patients
gastrin receiving
triggered by frequent or
action of high doses, or
calcium in who have
small impaired renal
intestines. function (see
Appendix F).

domperido motilium gastric 1mg/ml oral Acts as a CNS: headac *Instruct

ne stimulant neonates: peripheral he, insomnia patient to take
0.25mg/kg/ dopamine GI: dry as directed.
dose po receptor mouth Advise patient
q8h or q6 blocker. GU: amenorr
infants Increases GI hea, to avoid
greater motility, impotence grapefruit juice
than 40 peristalsis Derm: hot during therapy.
weeks PCA and lower flushes, rash *Advise patient
and 28 esophageal Endo: galact
to notify health
days of life: sphincter orrhea,
care
0.3-0.6 pressure. gynecomasti
professional if
mg/kg/dose Facilitates a,
galactorrhea
po TID or gastric hyperprolacti
QID emptying nemia (excessive or
dilute oral and spontaneous
solution decreases flow of breast
with water small bowel milk),
or feeds transit time. gynecomastia
just prior to Also (excessive
administrati increases development of
on prolactin male mammary
levels. gland),
menstrual
irregularities
(spotting or
delayed
periods),
palpitations,
irregular heart
beat
(arrhythmia),
dizziness, or
fainting occur.
*Advise female
 patient to notify
health care
professional if
pregnancy is
planned or
suspected or if
breast feeding.

digoxin lanoxin CARDIOVAS Digitalizin Widely used Rapid CNS: Fatigue, -Take apical
CULAR g Dose cardiac digitalization muscle pulse for 1 full
AGENT; CA glycoside and for weakness, min, noting
RDIAC Child: PO/I of Digitalis maintenance headache, rate, rhythm,
GLYCOSIDE; V <2 y, 40 lanata. Acts therapy in facial and quality
ANTIARRHY 60 by CHF, atrial neuralgia, before
THMIC mcg/kg; 2 increasing fibrillation, mental administering
10 y, 2040 the force atrial flutter, depression, drug.
mcg/kg; and velocity paroxysmal paresthesias, -Withold
>10 y, 10 of atrial hallucination medication and
15 mcg/kg myocardial tachycardia. s, confusion, notify physician
(1.52 mg) systolic drowsiness, if apical pulse
Neonate: P contraction agitation, falls below
O/IV 3050 (positive dizziness. ordered
mcg/kg inotropic CV: Arrhythm parameters
Premature effect). It ias, (e.g., <50 or
neonate: P also hypotension, 60/min in
O/IV 20 decreases AV block. adults and <60
mcg/kg conduction Special or 70/min in
Maintenan velocity Senses: Visu children).
ce Dose through the al -Be familiar
Child: PO/I atrioventricu disturbances. with patient's
V <2 y, lar node. GI: Anorexia, baseline data
7.59 Action is nausea, vomi (e.g., quality of
mcg/kg/d; 2 more prompt ting, peripheral
10 y, 67.5 and less diarrhea. pulses, blood
mcg/kg/d; prolonged pressure,
>10 y, than that of Other: Diaph clinical
0.1250.25 digitalis and oresis, symptoms,
mg/d digitoxin. recurrent serum
Neonate: 6 malaise, electrolytes,
7.5 dysphagia. creatinine
mcg/kg/d clearance) as a
Premature foundation for
neonate: 3. making
75 assessments.
mcg/kg/d -Lab tests:
Baseline and
periodic serum
digoxin,
potassium,
magnesium,
and calcium.
Draw blood
samples for
determining
plasma digoxin
levels at least 6
h after daily
dose and
preferably just
before next
scheduled daily
dose.
-Monitor for
S&S of drug
toxicity: In
children,
cardiac
arrhythmias are
usually reliable
signs of early
toxicity. Early
indicators in
adults
(anorexia,
nausea,
vomiting,
diarrhea, visual
disturbances)
are rarely initial
signs in
children.
-Monitor I&O
ratio during
digitalization,
particularly in
patients with
impaired renal
function. Also
monitor for
edema daily
and auscultate
chest for rales.
-Monitor serum
 digoxin levels
closely during
concurrent
antibiotic
digoxin
therapy, which
can precipitate
toxicity
because of
altered
intestinal flora.
Observe
patients closely
when being
transferred
from one
preparation
(tablet, elixir, or
parenteral) to
another; when
tablet is
replaced by
elixir potential
for toxicity
increases
since 30% of
drug is
absorbed.
fluconazol diflucan Antiinfectiv Oropharyng Fungistatic; CNS: Heada -Monitor for
e e, eal may also be che. GI: Nau allergic
antibiotic, Candidiasis fungicidal sea, response.
 antifungal Child: PO/IV depending vomiting, Patients allergic
36 on abdominal to other azole
mg/kg/d concentratio pain, antifungals may
Esophageal n. Interferes diarrhea, be allergic to
Candidiasis with increase in fluconazole.
Child: PO/IV formation of AST in -Lab tests:
36 ergosterol, patients with Monitor BUN,
mg/kg/d the principal cryptococcal serum
Systemic sterol in the meningitis creatinine, and
Candidiasis fungal cell and liver function.
Child: PO/IV membrane AIDS. Skin: -Note: Drug
36 that, when Rash. may cause
mg/kg/d depleted, elevations of
Cryptococc interrupts the following
al membrane laboratory
Meningitis function. serum values:
Child: PO/IV ALT, AST,
36 alkaline
mg/kg/d phosphatase,
bilirubin.
-Monitor for
S&S of
hepatotoxicity.
Digitalis Digoxin Antiarrhyth Force and Rapid Diarrhea; -Take apical
Glycosides digitoxin mic velocity of digitalization dizziness; pulse for 1 full
cardiotonic myocardial and for headache; min, noting
contraction maintenance nausea. rate, rhythm,
are therapy in and quality
increased CHF, atrial before
(positive fibrillation, administering
inotropic atrial flutter, drug.
effect). This paroxysmal -Withold
effect is atrial medication and
thought to tachycardia. notify physician
result from if apical pulse
inhibition of falls below
movement ordered
of sodium parameters
and (e.g., <50 or
potassium 60/min in
ions across adults and <60
myocardial or 70/min in
cell children).
membranes -Be familiar
by with patient's
complexing baseline data
with (e.g., quality of
adenosine peripheral
triphosphata pulses, blood
se. As a pressure,
result, there clinical
is symptoms,
enhancemen serum
t of calcium electrolytes,
influx and an creatinine
augmented clearance) as a
release of foundation for
free calcium making
ions within assessments.
the Lab tests:
myocardial Baseline and
cells to periodic serum
 subsequentl digoxin,
y potentiate potassium,
the activity magnesium,
of the and calcium.
contractile Draw blood
muscle samples for
fibers of the determining
heart. plasma digoxin
levels at least 6
h after daily
dose and
preferably just
before next
scheduled daily
dose.

`
Mannitol osmitrol Electrolyte Acute In large To promote CNS: Heada Take care to
and water Kidney doses, diuresis in che, tremor, avoid
balance Failure increases prevention convulsions, extravasation.
agent, Child: IV rate of and treatment dizziness, Observe
osmotic Test electrolyte of oliguric transient injection site for
diuretic Dose 200 excretion by phase of acute muscle signs of
mg/kg the kidney, kidney failure rigidity. CV: inflammation or
(max: 12.5 particularly following Edema, CHF, edema
g) over 35 sodium, cardiovascular angina-like -Lab tests:
min Positiv chloride, and surgery, pain, Monitor closely
e potassium. severe hypotension, serum and
Response traumatic hypertension urine
Urine flow injury, surgery , electrolytes and
of 1 in presence of thrombophle kidney function
mL/kg/h for severe bitis. Eye: Bl during therapy.
12 jaundice, urred Measure I&O
h Mainten hemolytic vision. GI: Dr accurately and
ance 0.25 transfusion y mouth, record to
0.5 g/kg reaction. Also nausea, achieve proper
q46 h used to reduce vomiting. Ur fluid balance.
elevated ogenital: M -Monitor vital
intraocular arked signs closely.
(IOP) and diuresis, Report
intracranial urinary significant
pressure (ICP), retention, changes in BP
to measure nephrosis, and signs of
glomerular uricosuria. M CHF.
filtration rate etabolic: Fl -Monitor for
(GFR), to uid and possible
promote electrolyte indications of
excretion of imbalance, e fluid and
toxic specially hyp electrolyte
substances, to onatremia; imbalance
relieve dehydration, (e.g., thirst,
symptoms of acidosis. Oth muscle cramps
pulmonary er: With or weakness,
edema, and as extravasatio paresthesias,
irrigating n (local and signs of
solution in edema, skin CHF).
transurethral necrosis; Be alert to the
prostatic chills, fever, possibility that
reaction to allergic a rebound
minimize reactions). increase in ICP
hemolytic sometimes
effects of occurs about 12
 water. h after drug
Commercially administration.
available in Patient may
combination complain of
with sorbitol headache or
for urogenital confusion.
irrigation. Take accurate
daily weight.
streptokin Kabikinas BLOOD Children: Derivative of Acute Body as a -Lab tests:
ase e, Strepta FORMERS, the beta- extensive Whole: Aller Discontinue
Not
se COAGULAT hemolytic deep venous gic heparin and
recommend
ORS, AND streptococci. thrombosis, reactions (br obtain baseline
ANTICOAG ed. Promotes acute arterial onchospasm, control levels
ULANTS; T thrombolysis thrombosis or periorbital for TT, aPTT,
HROMBOLY by activating embolism, swelling, PT, INR, Hct,
TIC the acute angioneuroti and platelet
ENZYME conversion pulmonary c count prior to
of embolus, edema, anap treatment.
plasminogen coronary hylaxis); Treatment is
to plasmin, artery urticaria, delayed until TT
the enzyme thrombosis, itching, and aPTT are
that MI, and headache, less than 2
degrades arteriovenous musculoskel times the
fibrin, cannula etal pain, normal control
fibrinogen, occlusion. flushing, level. During
and other nausea, treatment with
procoagulant pyrexia.Hem SK, TT is
proteins into atologic: Phl generally kept
soluble ebitis, bleedi at about 2
fragments. ng or oozing times or more
Decreases at sites of baseline value
blood and percutaneou and checked
plasma s q34h.
viscosity and trauma; prol -Protect patient
erythrocyte onged from invasive
aggregation systemic procedures: IM
tendency, hypocoagula injections are
thus bility; contraindicated
increasing spontaneous . -Also prevent
perfusion of bleeding (GI, undue
collateral urogenital, manipulation
blood retroperitone during
vessels. al). CV: Unst thrombolytic
able blood therapy to
pressure; prevent
reperfusion bruising.
atrial Spontaneous
or ventricular bleeding occurs
dysrhythmia about twice as
s. often with SK as
with heparin.
-Monitor for
excessive
bleeding
q15min for the
first hour of
therapy,
q30min for
second to
eighth hour,
then q8h.
Be aware that
patient is at
risk for
postthrombolyti
c bleeding for
24 d after
intracoronary
SK treatment.
Continue
monitoring vital
signs until
laboratory tests
confirm
anticoagulant
control. Report
signs of
potential
serious
bleeding; gum
bleeding,
epistaxis,
hematoma,
spontaneous
ecchymoses,
oozing at
catheter site,
increased
pulse, pain
from internal
bleeding. SK
infusion should
be interrupted,
then resumed
when bleeding
stops.
Report
promptly
symptoms of a
major allergic
reaction;
therapy will be
discontinued
and emergency
treatment
instituted.
Minor
symptoms
(e.g., itching,
nausea)
respond to
concurrent
antihistamine
or
corticosteroid
treatment or
both without
interruption of
SK
administration.
Check cardiac
monitor
frequently. Be
alert to
changes in
cardiac rhythm,
especially
during
intracoronary
instillation.
Dysrhythmias
signal need to
stop therapy at
once.
Monitor BP. Mild
changes can be
expected, but
report
substantial
changes
(greater than
25 mm Hg).
Therapy may
be
discontinued.