Council of Scientific & Industrial Res

search (C
CSIR)
Some K
Key Achiev vements
(overr last one year)

CSIR a also made great headway in de eveloping niche aeroospace tecchnologies.. CSIR and d
the Ind dia Meteorrological Department
D t (IMD) are jointly producing tthe Drishti system, a
visibilityy measurin
ng system that provid
des inform
mation to pilots on visiibility for sa
afe landing
g
and takke-off operations, soo as to enaable the deploymentt of 70 succh systems at Indian n
airportss. The sysstem has already
a be
een installe
ed in 5 ma ajor Indiann airports. CSIR-NAL L
has recceived the Make in India Excelllence Awa ard 2015 fo
or Drishti uunder R&D D category..

Dris
shti Transmis
ssometer

CSIR h has set up p a Micro Air Vehiclle Aerodyn namics Re esearch Tuunnel (MA ART) at the e
CSIR-N National Aerospace
A Laboratorries (CSIR R-NAL) cam mpus, Benngaluru. The T tunnel,
first of its kind in India, will be used to o test the fixed-wing, flapping-wwing and rotary-wing
r g
MAVs in the 500 0 mm wingspan cattegory. The tunnel was w set upp under th he Nationa al
Progra amme on MicroM Air Vehicles
V ((NP-MICAV V). The prroject is joointly coorrdinated byy
CSIR, the Defencce Research & Deve elopment Organizatio
O on (DRDO)) and the Departmen
D t
of Science & Technology. The state-of-th he-art tun
nnel woulld addres ss all the e
aerodyynamic, pro opulsion an nd aero-elaastic issues related to
o MAVs.

Collector

U? 300mmflapper

Balance
B

Support
System

BetzChamberr Flapper MAVtestinOpenTestS

SectionGustGenerator

 CSIR hhas been a consistent comrad e of the IS SRO and DAE.

D Its unnstinting strong
s R&D D
supporrt to the strategic
s se
ector has been mos st beneficial to the country. Gyrotron,
G a
device used in nuclear
n fussion proce ss, is currrently impoorted in th e country.. Countriess
that manufacture e gyrotrons s namely the United d States, Russia, Jaapan, and European n
Union ddo not discclose their designs a nd associa ated techno ology. Throough focus sed effortss,
CSIR wwith the Department
D t of Sciencce and Te echnology (DST) hass develope ed the firsst
Indian gyrotron which
w is ready to be tested at thet Institutte for Plasm ma Resea arch (DAE)),
Gandhinagar, wh hich is a paartner inst itute on this project. CSIR hass also been n providingg
supporrt in the developme
d nt, producction and supply
s of neodymiu m doped phosphate e
laser g
glass to the Raja Ra amanna C entre for Advanced
A Technologgy (DAE). DHVANI,
the Deetection and
a Hit Visualizatio
V on using Acoustic N-wave I dentificatio on system m

developed by CS SIR for pe

erfecting m
marksmans ship skills by accuraately deterrmining the
e
location
n of bulleet impact and provid ding real-ttime feedb
back, has been approved for
inductio
on into the
e Indian Arm
my.

DHVAN
NI - Detection and Hit Visu alization usin
ng Acoustic N-wave
N Identtification

CSIRss endeavo ours in the

e domain of traditio onal knowlledge for providing affordable e
healthccare have been prais seworthy. A An anti-dia
abetic herb
bal formulaation BGR--34, from a
combin nation of natural
n exttracts deriived from six plant species m mentioned in ancient
Ayurveeda texts has
h been developed
d . The drugg which waas approveed by the Ministry of
o
Ayurveeda, Yoga and Natu uropathy, U Unani, Sidddha and Homoeopaathy (AYU USH) is an n
adjuvant to existting diabettes treatm ent, to help maintain normal bblood gluc cose levelss
and also in improving the e immune system. The T herbal drug hass been launched byy
industrry in parts of
o North In
ndia.


Anti-dia
abetes Drug BGR-34

Furtherr, a national cGMP facility

f for extraction,, formulatio
on and pacckaging off traditiona al
herbal mediciness has bee en set up at CSIR--Indian Ins stitute of Integrative e Medicinee
(CSIR--IIIM), Jam mmu. It has been crea ated as perr WHO guidelines. Thhe facility willw also be e
made available to t R&D institutions a and industtry. The fa acility will ttarget preparation of
o
extractts and form mulations foor conductting clinica
al trials, pro
ocess deveelopment, scale-up &
optimizzation of lab- pro ocesses a and conve erting the em into ccommercia ally viable
e
technoologies bessides gene eration of authentic and accurrate clinicaally accepttable data a.
This fa
acility will trransform quality herbbal drug prooduction inn India andd its exportt to US andd
Europe ean marketts.

cGMP PPilot Plant at CSIR-IIIM
C
(For Extrraction, formu
ulation and p
packaging of Traditional
T (IS
SM) Herbal M
Medicines)

The faarmers are e the backbone of o our countryy. CSIR haas developped and released
r to
o
farmerss a new im
mproved hig gh yielding
g variety off Ashwagandha, NMIITLI-101 which
w is rich
h
in seve
eral bioactiive compoounds. The e average root yield from
f NMITTLI-101 cro op is about
25 quinntal/hectarre and the seed prodduction from the variety is up too 3 quintal/ha, under
optimum conditio ons. The estimated
e economic return froom cultivattion of this
s variety iss
about RRs. 2.5 Lakkh/hectare
e per crop.

Ashwa
agandha, NMIITLI-101

CSIR h has also laaunched th he JK Arom ma Arogya a Gram (JA AAG) projeect which targets job b
and we ealth creattion through intensive e cultivatio R agri-technnology of high
on of CSIR h value
e,
low voolume med dicinal andd aromatic crops. Th he benefits
s of the JJAAG proje ect includee
handho olding of th
he farmers by CSIR ffor cultivation of med dicinal plannts, besides providingg
unemp ployed youth an oppo ortunity to set up ve entures in cultivationn of mediciinal plantss.
Awaren ness camp mers of the area besiides demonstrations of Mobile Distillation
ps for farm n
Unit for extraction of essen ntial oils arre conductted. Started in July 22015, so fa ar, seventyy
three ffarmers inn 14 villages of Katthua distric ct (J&K) have
h beenn distributeed slips of
o
lemong grass, Java a citronella
a and vetivver for culttivation in 17.47 hecctares area a under the e
JAAG p project.
Also fo
ocusing at Reaching g to the Unnreached, CSIRs Centre
C for H
High Altitude Biologyy
(CSIR--CeHAB) in Lahaul and Spiti is providing deploy yable know wledgebasse to locaal
commu unities for inclusive growth.
g e CSIR kn
The nowhow related to foood & agri-processingg
was sh howcased at the Trribal Fair a at Keylong
g for the benefit
b of the local farmers in
n
makingg novel prroducts fro om major ccrops of the region such as B Buckwhea at and also
o
brining of the peaas and cau uliflower.

CSIR hhas publish hed whole genome ssequence of Ocimum m sanctum m, the sacred plant of o
Hindu ttradition. The
T nuclea ar genome of Holy ba asil is the smallest (3386 Mb) inn the familyy
Lamiacceae while e the chlo oroplast ge enome (14 42,245 bp)) is the s mallest in the order
Lamiales. This iss the first re
eport of co omplete genome sequ uence of thhe holy baasil, using a
compoosite next generation n sequenccing technologies. The T availabbility of th
he genome e
sequennce openss the poss sibility to identify genes involved in prroducing therapeutic
t c
molecu
ules and to o produce them
t in vitrro.
As parrt of effortts towards s developinng sustainnable enerrgy solutioons, CSIR under the e
CSIR-NNMITLI, ha as successfully deve eloped inddigenous know-how
k to make technologyy
compo onents and d the process for building ProtonP Exchange M Membrane Fuel Celll
(PEMF FC) multi-ccell stack of
o desired power outtput. CSIR has takenn existing technologyy
know-hhow from stack-to-sy
s ystem leveel higher by
b scaling-up the pow wer produ
uced to 3.5 5
kW and d validating it for a commercia
c al applicatio
on such ass telecom ttower pow
wer backup p.
For thiss, a modular test be ed has beeen designe ed, built an
nd commis sioned witth in-house e
knowho ow at Re eliance Ind dustries L
Ltd (RIL), Patalgang ga site. TThe fuel cell
c facilityy

 commissioned now,
n is ex
xpected to o provide plenty off useful ddata for te
esting and
d
developing indige
enous fuel cells at low
w costs forr commerc
cial applicaations.

F
Fuel Cell Tes
st-bed

Plastics consumption in In ndia is repoorted to be around ~10 MMT T (2010) while plasticc
wastess in India are ~15,0 000 TPD amounting g to high environmeental pollu ution. As a
potential solutionn to addres ss the gro
owing menace of pla astic usagee and the associated d
waste g generationn in the cou
untry, CSIRR has deve eloped a fa
acile proceess for the conversionn
of wasste plasticss (polyoleffins) to vallue added hydrocarb bons e.g. gasoline, diesel and d
aromattics. The salient
s fea
atures of tthe techno ology are that the pprocess prrovides for
exclusiive producction of either gaso line or die esel or aromatics aalong with LPG from m
polyole
efinic wasttes (e.g. HDPE,
H LD
DPE, PP etc)e and the
t liquid fuel meetts Euro III
specificcations. Fu
urther, thee process is simple, pollution free and eenvironment friendlyy.
The esstimated pa ayback perriod for a 3
30 TPD pla ant is aboutt ~ 3 yearss.

Waste Plasttic to Petroleu
um Products

Applicaation of biofuels for aviation iis an effecctive mean ns for the aviation industry too
reducee its carboon footprint. CSIR h as developed a pro ocess as w well as a catalyst to
o
producce jet fuel based
b on biomass-de
b erived non
n-edible oils s such as jjatropha oil.
o The bio-
jet fuell has beenn able to match
m all tthe major specificatiions for avviation fue
els such ass
petrole
eum derive ed jet fuel. The proce ess develo
oped is verry similar tto refinery processess
and heence can be e integrate
ed into the current reffinery infra
astructure.


Pilot Plant C
Capacity: 100
0 kg feed/day

CSIR h has conduccted the analysis, deesigning annd structurral detailingg of (G+1) reinforced
d
concreete building
gs using Expanded
E Polystyrenne (EPS) Panels.
P Thhe salient features
f o
of
the tecchnology are:
a faster mode of cconstructio on; ideal fo
or mass p roduction of housess;
afforda
able; and disaster
d resistant - ccyclone winnd loads. The
T develooped techn nology hass
been transferred to Conso ortium Tran nsmission Systems Pvt. Ltd. ((CTSPL), Hyderabad d
for Hu
udhud cycclone victim
ms rehabillitation hou
using proggramme att Srikakula am, Andhra a
Pradessh. About 496
4 dwellin ng units aree being constructed using the ttechnology y.
A Mobile Pilot Plant for Toxic Emissiion Monito oring and Control
C hass been dev veloped byy
CSIR-N NEERI, Na agpur for undertaking
u g flue gas emission monitoringg and conttrol studiess
in varioous industtries includ ding Smal l and Med dium Scale e Industriees (SMEs)). Flue gass
comprising of du ust of different sizes and gases of varyin ng concenntrations re epresentingg
differen
nt small sccale industtries such as ceramic kilns, ho ot mix plannts, other small
s scalee
industrries etc. will be monittored for itts emission
n characte erization. PPart of the gas will be
e
fed intoo the different contro ol systemss and theirr collectionn efficienciies will be measured d
with reespect to time, tem mperature, flow etc. The perfformance in terms of techno-
econom mic feasib bility will be
b checked d and a system
s forr control oof emissioons will bee
provideed in the pilot scale which
w can bbe scaled up for full scale
s instaallation.

Mobile Air P
Pollution Mon
nitoring Van

CSIR h has develo

oped new energy effficient, eco onomically viable andd more en nvironment-
friendlyy process technologi
t es for prep
paration off various nano-catalyysts, which
h are usefu
ul
for sevveral challe
enging cattalysis reacctions. Thee novel naano-catalyssts have been
b found
d

 effective in catalyzing reactions such as selective oxidation of benzene to phenol,

propylene to propylene oxide, low temperature methane activation, and ethane to
ethylene conversion in a continuous process at atmospheric pressure. These are
industrially important chemicals/petrochemicals.
CSIR has developed micro-channel reactors with stable catalyst coating formulations
that are used to intensify the processes involving vegetable oils. These reactors have
great impact on the product yield and conversion in hydro-processing of vegetable oils.
The micro-channel reactors find immediate applications as a tool to intensify the process
at places where there is inadequate supply of raw material such as biomass; and where
transportation of feedstock, fossil fuels, is a problem. CSIR has used the micro-channel
reactors to convert non-edible oil and biomass-derived oil (pyrolysis-oil), biomass-
derived gases (syn-gas) and coal derived gasses (coal gasification to syn-gas) into
second and third generation biofuel. Use of such reactors has resulted in improved
reaction selectivity and throughput and thus higher product yield.
Plasma gelsolin, a circulating actin-binding protein serving a protective role against
tissue injuries is fast emerging as a health condition biomarker. Depletion of plasma
gelsolin in systemic inflammation contributes to adverse outcomes. CSIR has developed
two mass-production ready plate based kits to estimate plasma gelsolin levels in
humans. While, most other labs including commercial set-ups are focusing on improving
bulk production of this protein, CSIR has developed bonsai versions of this protein by
structure-based insights and has successfully demonstrated the anti-sepsis properties of
the miniaturized versions in LPS-induced sepsis model of mice. The kits thus developed
will help in determining a quantitative measure of sepsis. The laboratory is also testing
the kits viability in predicting cases of preterm birth.
Under GUaRDIAN, a one of its kind research programme, CSIR is focused at the
development of genomics based diagnostic tools for understanding rare diseases. The
programme with extensive collaboration between clinicians and researchers is targeted
at better understanding the genetic basis and molecular mechanisms of rare genetic
disorders using advanced genomic technology. The findings pave way to newer
diagnostic methods such as exome sequencing based tools which could be an
alternative to traditional gene sequencing approach to quickly identify the variations and
be able to make an appropriate diagnosis in clinical settings.
CSIR has played a major role in protecting Indias rich traditional knowledge in
healthcare by creating the TKDL. The TKDL involves documentation of the traditional
knowledge available in public domain in the form of existing literature related to
Ayurveda, Unani, Siddha and Yoga, in digitized format. The TKDL currently contains
information concerning 2.93 lakh medicinal formulations in Ayurveda, Unani and Siddha
in 5 international languages, i.e., English, Japanese, Spanish, French and German.
Access to the TKDL is available to Patent Offices only under TKDL Access Agreement.
Recently, CSIR through the TKDL has successfully contested an attempt made by
consumer goods giant M/s Colgate-Palmolive Company (United States of America) to
patent a Mouth-wash formula containing herbal extract. Prior art evidences from TKDL
provided that the claims made in the patent application filed by M/S Colgate-Palmolive

 Company were not novel and the use of claimed constituents of the mouth wash under
reference was already mentioned in Indias traditional medical literature such as
Ayurveda and Unani. Another important success was achieved when a leading UK-
based Pangaea Laboratories Ltd.'s move to patent a medicinal composition containing
turmeric, pine bark and green tea for treating hair loss was thwarted by the TKDL. The
TKDL is proving to be an effective deterrent against bio-piracy and is being recognized
as a global leader in the area of traditional knowledge protection.