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Omg come onnnnn

Problems:
False-Positive: VDRL after strong immunological stimulus
FTA-ABS other spirochetes
Treatment:
Penicillin
Alternative erythromycin ()
Jarisch-Herxheimer reaction

Nisseria gonorrhea non-motile, gram (-) diplococcus; kidney-bean shaped


()
Virulence Factors:
1. Capsule anti-phagocytic
2. Pili adherence; transfer of DNA
3. IgA protease evade sIgA
4. LPS release of endotoxin induces inflammations
5. Outer membrane proteins adhesions

Pathogenesis
Nisseria stick to mucous secreting but non ciliated ()
Endocytosis directed by porins ()
Massive inflammation
Destruction of ciliated and non-ciliated host cells
Organism resist killing Ab
Attachment to endothelial cells ()

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