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Hydrolysis & Dehydration Synthesis 7 When Cell Communication Goes Wrong. Retrieved from http://
learn.genetics.utah.edu/content/cells/badcom/.
Intracellular & Extracellular Fluid 8
Plasma Membrane 10
Cell Signaling 14
Training Manual
Page 4 Page 25
Carbohydrates References
Function & Structure 10 Symptoms of Kidney Disease. Retrieved from http://
lifeoptions.org/kidneyinfo/ckdinfo.php?page=3.
Carbohydrates are sugars,
made out of monosaccha- (2006). Carbohydrates. Retrieved from http://www.hippocampus.org/
rides, also known as sim- player/
ple sugars. Examples of top-
simple sugars include glu- icText;jsessionid=8AFD3022DA97FF551BBD7F988E2906
cose, fructose, and galac- 4A?topic=163.
tose. The structure in-
cludes a carbon skeleton (2015, February 9). What Is Cancer? Retrieved from https://
that creates a ring shape. www.cancer.gov/about-cancer/understanding/what-is-
Carbohydrates provide the cancer#how-cancer-arises.
body with energy so that it
can do work. (2015, February 13). Symptoms of Tay-Sachs disease. Retrieved
Carbohydrate Polymers from http://www.nhs.uk/Conditions/Tay-Sachs-disease/
2 different types of polysaccharides include starch and cellulose. Pages/Symptoms.aspx.
Starch helps store energy in plants, and when animals consume
the plants, they also get energy from starch. The polysaccharide (2015). Passive transport and active transport across a cell mem-
is made up of multiple glucose monomers in a granular struc- brane article. Retrieved from https://
ture. www.khanacademy.org/test-prep/mcat/cells/transport-
Cellulose strands make up the strong fibers that strengthen
across-a-cell-membrane/a/passive-transport-and-active-
plants' structures. It is also a polysaccharide made up of glu-
transport-across-a-cell-membrane-article.
cose monomers, however the linkage differs from that of starch.
While starch's glucose monomers point in the same direction,
the glucose monomers in cellulose point in opposing directions. (2016, June 14). Lymph Transport. Retrieved from https://
www.boundless.com/physiology/textbooks/boundless-
anatomy-and-physiology-textbook/lymphatic-system-20/
lymphatic-vessels-192/lymph-transport-958-4522/.
(2016, August 8). Blood Flow Through the Body. Retrieved from
https://www.boundless.com/biology/textbooks/boundless-
biology-textbook/the-circulatory-system-40/blood-flow-and
-blood-pressure-regulation-227/blood-flow-through-the-
body-854-12099/.
Page 24 Page 5
Cytosol is the intracellular fluid, and it is made of pro- Passive transport of fluid include:
teins, ions, and organelles dissolved in water. It holds Osmosis
organelles of the cell in suspension. Osmosis occurs when water is diffused across the plasma
membrane. Water travels through aquaporins, water chan-
nels, found within the membrane. It moves from a high water
Extracellular Fluid concentration to a low water concentration.
Extracellular fluid is all of the fluid surrounding the cell, Dialysis
and it is made of blood plasma, interstitial fluid, and Dialysis separates solutes by
the size of their molecules. It
transcellular fluid. Blood plasma holds blood cells in
determines which solutes can
suspension, and it contains proteins and glucose, so enter the selectively permeable
the levels of sugar in the blood needs to be monitored membrane of the cell.
in IV fluids. Interstitial fluid bathes the cells of the body Filtration
and is found in between tissue spaces. It contains dis- In filtration, a driving pressure forces fluid through the filter of a cell.
solved proteins and solutes, such as sugar, electro- The cell can filter what molecules can pass through depending on
lytes, and hormones. Thus, it is important to make sure the size of the pores of its membrane.
the amount of solutes inside and outside the cell are
balanced and achieve homeostasis. Transcellular fluid
is the measure of total body water, which is usually
about 2.5%.
Page 20 Page 9
Tay-Sachs Disease
Tay-Sachs disease occurs when lysosomes swell to
massive proportions due to the build of fat in the nerve
cells. Fat builds up because the cell lacks the enzymes
in the lysosome that would regularly recycle waste.
This disease does not have a cure, but testing for the
Selective Permeability gene carrying the disease is advised before conception.
The phospholipid bilayer allows nonpolar, hydrophobic Symptoms of Tay-Sachs include:
molecules to enter the membrane easily, but it does not >Blindness
allow polar, hydrophilic molecules to pass through. Ad- >Deafness
ditionally, transport proteins across the membrane are
>Difficulty swallowing
specified and determine which molecules are allowed to
>Seizures
enter the cell. All of these components to the mem-
brane result in selective permeability because they reg- >Cherry-red spot visible in eye
ulate what can or cannot enter the cell. (Shown on pg. 9)
Page 18 Page 11
11. Chloroplast Why do cells need a high surface area-to volume ratio?
Chloroplasts aid in photosynthesis which converts Cells require such a high surface area-to-volume ratio
energy from the sun into food. Chloroplasts work because they need to be able to diffuse necessary raw
together with the mitochondria as the food is bro- materials into themselves. The size of the cell deter-
ken down and converted into ATP. mines the size of the plasma membrane, which in turn
determines the importation or exportation of molecules
12. Central vacuole in and out of the cell. The smaller the cell, the surface
area-to-volume ratio raises, and the faster it can diffuse
The central vacuole stores and breaks down waste,
raw materials into itself. On the other hand, if the cell is
and within it, the process of hydrolysis occurs. It bigger, the surface area-to-volume ration lowers, and it
also aids in plant growth when enlarged. takes a longer time for raw materials to provide for it.
3. Flagellum
The flagellum is what motors the cell, and it is
attached to the cytoplasm of the cell through the
plasma membrane. It works with the cytoskele-
ton during the cell's movement.
Homeostasis
4. Cytoskeleton
The cytoskeleton provides the cell with structural support
In order to maintain homeostasis, the intracellular and
and works together with the flagellum to give the cell mobili- extracellular conditions are constantly changing.
ty. Transport maintains homeostasis because it allows the
cell to remove waste but also take in nutrients.
Transport plays the role of making sure the cell is in a
stable condition.
Page 14 Page 15
Overall, there are three steps that take place during cell
signaling. They are reception, transduction, and re-
sponse. During reception, the target cell recognizes a
molecule coming into the cell. During transduction, the
signal changes and becomes more specified for the de- Diabetes
sired cellular response. Finally, during response, the Cells of the pancreas release insulin, a hormone, that allows glu-
cose to be stored for energy in other cells. However, when pan-
signal produced triggers a response that causes activi- creas' cells signals are interrupted, the insulin signal dies out
ty. and sugar begins to build up in the blood. This can cause high
blood sugar and diabetes. Diabetes can lead to heart attack, kid-
ney disease, and also blindness.
Multiple Sclerosis
During synaptic signaling, nerve cells can
be destroyed and cannot emit signals from
nerve to nerve. This can cause multiple
sclerosis because the brain cannot send
signals to the spinal cord. Symptoms of
multiple sclerosis include blurry vision,
numbness, and weakness in the body.