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DRUG ORDER
(Generic name, brand name,
classification, dosage, route, MECHANISM OF ACTION INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS OF THE NURSING RESPONSIBILITIES/
frequency) DRUG PRECAUTIONS

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Generic Name: cilostazol
Brand name: Pletal
Classification: cardivascular phosphodiesterase III,
system drugs
Dosage: 1 tab. 50mg
Route: P.O.
Frequency: b.i.d.
A quinolone derivative èÊ Reduction
thought to inhibit the
enzyme
thus inhibiting platelet
aggregation and causing
vasodilation.
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of èÊ Contraindicated in >CNS: headache, dizziness, > use cautiously in patients
symptoms of patints hypersensitive vertigo with severe underlying heart
intermittent to drug or its disease; also use cautiously
>CV: palpitations tachycardia,
claudication components and i
pripheral edema
with other drugs having
those with heart failure antiplatelet activity.
of any severity. >EENT: pharyngitis, rhinitis
> drug should be given at least
>GI: abnormal stools, 30 minutes before or 2 hours
diarrhea, dyspepsia, after breakfast and dinner.
abdominal pain, flatulence,
> benficial effects of drug may
nausea
be not be seen for up top 12
>Musculoskeletal: back pain, weeks after start of therapy.
myalgia > drug may cause reducd
>Respiratory: increased cough triglyceride levels and
increased HDL cholesterol
>Other: infection level.

> advise patient to avoid

drinking grapefruit juice
during drug therapy.

> tell patient that drug may

cause dizziness. Caution
patient not ot drive or
perform activities thatr equire
alertness until response to
drug is known.

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DRUG ORDER
(Generic name, brand name,
classification, dosage, route, MECHANISM OF ACTION INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS OF THE NURSING RESPONSIBILITIES/
frequency) DRUG PRECAUTIONS

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Generic name: ciprofloxacin
Brand name: Ciproxin
Classificatioon:
Fluoroquinolones
Dosage: 1 tab 500 mg.
Route: P.O.
Frequency: b.i.d.
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Inhibits bacterial DNA èÊ Mild to moderate èÊ Containdicated in > CNS: headache, restlessness, > use cautiously uin patients
synthesis, mainly by urinary tract patients sensitive to tremor, dizziness, fatigue, with CNS disorders because it
blocking Dna gyrase; infection (UTI). fluoroquinolones. drowsiness, insomnia, may cause CNs stimulations.
bactericidal. èÊ Mild to moderate depression, light-headedness,
> oral form 2 hours after a
bone and joint confusion, hallucinations,
infections. seizures, paresthesia. ameal or 2 hours before or
after taking antacids.
èÊ Chronic bacterial
> CV: thrombophlebitis,
prostatitis > monitor patients I&O and
eddema, chest pain.
èÊ Complicated observe for signs of
intre-abdominal > GI: nausea, diarrhea, crystalluria.
infections vomiting, abdominal, pain or
èÊ Acute discomfort, oral candidiasis, >advise patient to drink
uncomplicated plenty of fluids to reduce risk
pseudomembranous colitis,
cystitis of crystalluria.
dyspepsia, flatulence.
èÊ Mild to moderat
> warn patient to avopid
acute sinusitis > GU: crystalluria, interstitial
nephritis. hazardous tasks that require
èÊ Empirical therapy
alertness, such as driving,
in febrile
> Hematologic: eosinopenia, until CNS effects of drug are
neutropenic
leukopenia, neutropenia, known.
patients.
thrombocytopenia.
èÊ To reduce the > intsruct patient to avoid
incidence of > Musculoskeletal: arthralgia, caffeine while taking drug
progression of arthropathy, joint or bacj because of potential for
disease following pain, joint inflammation, increased caffeine effects.
exposure to
aerosolized >Skin: rash, photosensitivity > tell patient to report pain.
Bacillus anthracis
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DRUG ORDER
(Generic name, brand name,
classification, dosage, route, MECHANISM OF ACTION INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS OF THE NURSING RESPONSIBILITIES/
frequency) DRUG PRECAUTIONS

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Generic name: omperazole Inhibits activity of acid èÊ Symptomatic èÊ Contraindicated in > CNS: headache, dizziness, > dosage adjustments aren͛t
(proton) pump and gastroesophageal patients hypersensitive asthenia,. needed for patients with renal
Brand name: Prilosec binds to hydrogen- reflux disease to drug or its or hepatic impairment.
> GI: diarrhea, abdominal
Classification: antiulceer potassium adenosine (GERD) without components.
pain, nausea, vomiting,
> omeprazole increases its
drugs triphosphate at esophageal
secretory surface of lesions constipation, flatulence own bioavailability with
Dosage: 1 tab 20mg. repeated doses. Drug is labile
gastric parietal cells to èÊ Erosive > Muscuskeletal: back pain in gastric acid; less drug is lost
block formation of esophagitis
Route: P.O. > Respiratory: cough, upper to hydrolysis because drug
gastric acid. èÊ Maintenance of
respiratory tract infection increases gastric pH.
Frequency: o.d. healing erosive
esophagits > ALERT: don͛t confuse
> Skin: rash
èÊ Pathologic Prilosec with Prozac,
hypersecretory Prilocaine, or Primivil
conditions
(Zollinger-Ellison > serum gastrin levels rise in
Syndrome) most patients during theb first
èÊ Duodenal ulcer 2 weeks of therapy.
èÊ H. Pylori
> tell patient to swallow
infection and
capsules whole and not to
duodenal ulcer
open, crush, or chew them.
disease
èÊ Short-term > instruct patient to take drug
treatment of 30 minutes before meals.
active benign
gastric ulcer > caution patient not to
perform hazardous activities if
dizziness occurs.

DRUG ORDER
(Generic name, brand name,
classification, dosage, route, MECHANISM OF ACTION INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS OF THE NURSING RESPONSIBILITIES/

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frequency) DRUG PRECAUTIONS

Generic name: arcoxia The body produces two èÊ cute and chronic > You have had heart failure, a yÊ Nausea and vomiting > you are breast-feeding or
similar enzymes called treatment of the heart attack, bypass surgery, yÊ heartburn, plan to breast-feed
Brand Name: Etoricoxib COX-1 and COX-2. COX- signs and chest pain (angina), narrow or indigestion, It is not known if Arcoxia
1, among other symptoms of blocked arteries of the uncomfortable feeling passes into breast milk. You
Classification: functions, is involved osteoarthritis extremities (peripheral arterial or pain in the stomach and your doctor should
cyclooxygenase-2 with protecting the and rheumatoid disease), a stroke or mini yÊ diarrhea discuss whether you should
stomach, while COX-2 arthritis stroke (TIA or transient yÊ swelling of the legs, stop breast-feeding or not
Dosage: 1 tab 120 mg. plays a role in joint èÊ management of ischaemic attack). ankles or feet take Arcoxia.
inflammation and pain. ankylosing yÊ high blood pressure
Route: P.O. Arcoxia reduces pain spondylitis > You have high blood pressure yÊ dizziness > you have or have had any
and inflammation by èÊ relief of chronic that is not well controlled on yÊ headache medical conditions, especially
Frequency: o.d. blocking COX-2, an musculoskeletal allergic reactions the following:
blood pressure medication. yÊ
enzyme in the body. pain including rash, itching history of angina, heart attack
Arcoxia relieves pain èÊ relief of acute > You are having major surgery and hives or a blocked artery in your
and inflammation with pain and have conditions which yÊ severe skin reactions, heart
less risk of stomach èÊ to treat acute increase your risk of coronary which may occur narrow or blocked arteries of
ulcers compared to gouty arthritis artery disease or without warning the extremities
NSAIDS. However taking atherosclerosis such as high yÊ taste alteration kidney disease
aspirin with Arcoxia blood pressure, diabetes, high yÊ wheezing liver disease
may reverse this benefit cholesterol or smoking. yÊ insomnia heart failure
yÊ anxiety high blood pressure
> You are having major surgery yÊ drowsiness
on you heart or arteries. yÊ mouth ulcers > you have an infection
yÊ diarrhoea If you take Arcoxia while you
yÊ severe increase in have an infection, it may hide
blood pressure fever and may make you
yÊ confusion think, mistakenly, that you are
yÊ hallucinations better.
yÊ platelets decreased

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DRUG ORDER
(Generic name, brand name,
classification, dosage, route, MECHANISM OF ACTION INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS OF THE NURSING RESPONSIBILITIES/
frequency) DRUG PRECAUTIONS

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Generic name: valsartan
Brand name: Diovan
Classification:
antihypertensive drugs
Dosage: 1 tab 80mg.
Route: P.O.
Frequency: o.d.
DRUG ORDER
(Generic name, brand name,
classification, dosage, route,
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Blocks the binding of èÊ Hypertension èÊ Contraindicated in >CNS: dizziness, headache, >use cautiously in patints with
angiotensin II to patients with insomnia, fatigue. renal or hepatic disease
receptor sites in hypersensitivity to
> CV: edema > watch for hypotension.
vascular smooth drug. Use in pregnant
Excessive hypotension can
muscles and the adrenal and breast-feeding > EENT: rhinitis, sinusitis,
gland, ehich inhibits the patients isn͛t occur when drug is given with
pharyngitis
high doses of diuretics.
pressor effects of the recommended.
renin-angiotensin- > GI: abdominal pain, Correct volume and salt
diarrhea, nausea depletions before starting
aldosterone system.
drug.
> Hematologic: neutropenia
> drug can cause fetal or
> Metabolic: hyperkalemia neonatal morbidity and death
if given to a pregnant woman
> Muscuskeeletal: arthralgia
in the second or third
> Respiratory: upper trimester. Breastfeeding
respiratory tract infection, women shouldn͛t take drug.
cough
> advise patient thatd rug may
Other: viral infection. be taken without regard to
food.
MECHANISM OF ACTION INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS OF THE NURSING RESPONSIBILITIES/
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frequency) DRUG PRECAUTIONS

Generic name: kalium durule Supplemental èÊ Hypokalemia. èÊ Potassium èÊ potassium chloride

potassium in the form supplements are causes additive >To take each dose with
Brand name: Flexyx Prophylaxis
of high potassium food contraindicated in toxicity with amiloride meals mixed in water or other
during treatment patients with
Classification: Potassium or potassium chloride suitable liquid.
w/ diuretics. hyperkalemia since a
Supplements may be able to restore further increase in
normal potassium levels >To take this medicine
serum potassium following the frequency and
Dosage: 1 tab 750mg concentration in such amount prescribed by the
patients can produce physician. This is especially
Route: P.O. cardiac arrest. important if the patient is also
Hyperkalemia may taking diuretics and/or
Frequency: t.i.d. complicate any of the
digitalis preparations.
following conditions:
chronic renal failure,
> To inform patients that this
systemic acidosis such
product contains as a
as diabetic acidosis,
dispersing agent the stool
acute dehydration,
softener, docusate sodium,
extensive tissue
which may change stool
breakdown as in severe
consistency, or, rarely,
burns, adrenal
produce diarrhea or cramps.
insufficiency, or the
administration of a
> To check with the physician
potassium-sparing
at once if tarry stools or other
diuretic (e.g.,
evidence of gastrointestinal
spironolactone,
bleeding is noticed.
triamterene,
amiloride).

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