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The future of
intelligent food
Where food and
pharmaceuticals converge
kpmg.com
The term
nutraceuticals was
coined in the late
1980s to describe
food products that have
a medicinal benefit.
This fast-growing sector
includes functional foods
(such as vitamin-enriched
products), nutritional
supplements, sport
drinks, and medically
formulated foods.
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Nutraceuticals: The future of intelligent food | 1
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2 | Nutraceuticals: The future of intelligent food
Key nutraceutical
product hot spots
GASTROINTESTINAL HEALTH
Background: Gut health issues, from Pipeline: There is continued investment into
indigestion through to more serious conditions free from products. This is driven by the
like celiac disease motivate consumers to increasing number of people claiming to be
look to over-the-counter symptom relief. It is intolerant to certain ingredients, for example
estimated that over 100 million people globally gluten and lactose, although few people have a
are effected by gut health problems and the diagnosed intolerance5. One example is Alpos
prevalence is rising2. Household products (like successful almond milk product offering an
Yakult and Actimel, see page 14) help to provide alternative for people with lactose intolerance,
some symptom relief. They have a positive and claiming to have many other health benefits
effect on the millions of organisms that live in over cows milk.
the human intestine (known as gut flora)3. Many
consumers purchase some form of probiotic
product and the market is growing4.
1http://www.who.int/medicines/areas/priority_medicines/BP6_11Alzheimer.pdf
2http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/Pages/default.aspx
3http://www.ncbi.nlm.nih.gov/pubmed/11590374
4http://www.nutraingredients.com/Markets-and-Trends/Global-probiotics-market-to-grow-6.8-annually-until-2018
5 According to a recent survey 1 in 3 people claim to be intolerant of gluten
6http://www.who.int/mediacentre/factsheets/fs317/en/
7http://ajcn.nutrition.org/content/8/4/445.full.pdf
8http://www.who.int/diabetes/en/
9 http://www.nutraceuticalsworld.com/issues/2013-03/view_features/gut-instincts-the-right-moves-for-protecting-digestive-health/#sthash.ynH0QZIG.dpuf
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Nutraceuticals: The future of intelligent food | 3
The shift in healthcare from treatment to prevention is encouraging
clinicians and patients to think differently about health and disease, and
creating momentum for nutraceuticals, with opportunities for pharma and
food companies to get involved in the disease/care pathway.
Professor Ajit Lalvani,
Chair of Infectious Diseases, Imperial College, London
and Non-Executive Director, Vitabiotics
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4 | Nutraceuticals: The future of intelligent food
Food companies have a greater understanding than Among the pharmaceuticals companies with a strong
pharmaceuticals of nutrition and food formulation, plus presence in nutraceuticals, Abbott owns some of the
decades of consumer research and relationships with leading nutritional product brands. Pfizer sells a range
mass-market distributors. Food companies who are doing of dietary supplements. Johnson & Johnson makes
well in nutraceuticals include those that have created products to lower cholesterol and dietary supplements for
separate health divisions, acquired successful brands, and people who are lactose intolerant. Some pharmaceuticals
launched global health improvement plans. companies have attempted wider public awareness
campaigns for nutraceuticals, but few, if any, have the
However, despite a commitment to innovation, food
competence to influence behavioral change on a wide
businesses lack some of the in-depth scientific resources
scale. There is also the question of how to accommodate
that are needed to come up with major breakthroughs.
consumer-oriented brands within existing portfolios, with
Innovation in food tends to involve modest improvements
such products typically delivering smaller margins than
such as reduced sugar, salt or fat levels, or novel-tasting
traditional drugs.
products. As a result, food companies may struggle
to achieve the kind of game-changing breakthroughs By complementing each others strengths (and
necessary to open up new nutraceutical markets. weaknesses), a merger of the nutraceuticals portfolios of
Furthermore, shareholders could be impatient over the a big food company and a big pharmaceuticals company
longer development times associated with nutraceutical might make sense, but there hasnt been a significant
products. one yet. Instead, there has been a blurring of the line
demarcating the two industries and an active market
Pharmaceuticals companies face a different set of
for corporate transactions involving relatively small
difficulties. They have strong research departments,
acquisitions and sell-offs. These maneuvers are preliminary
stakeholder relationships and regulatory structures that
skirmishes; the battle for dominance in the nutraceuticals
enable them to generate new compounds, plus wider
market seems a long way off. But the war against chronic
ties to the scientific community. Yet, despite their large
and lifestyle related diseases is already in full swing.
sales and marketing resources, most of their efforts are
Functional superfoods probably have an important role to
aimed at medical professionals and pharmacists rather
play in the struggle, and its only a matter of time before the
than consumers. Only a small number of pharmaceutical
fight spills over into corporate takeover wars.
companies have a consumer arm. An organizational culture
devoted to blockbuster drugs and long research cycles may At some point, a nutraceuticals powerhouse will emerge,
struggle to adapt to the faster pace of the nutraceuticals but what will it take to build one? Whether it grows
market. organically or by acquisitions or a combination of the two,
certain key attributes will be required.
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6 | Nutraceuticals: The future of intelligent food
1http://www.thegrocer.co.uk/channels/supermarkets/tesco/tesco-reveals-clubcard-healthier-eating-plans/343589.article?utm_source=rss_feed&utm_medium=rss&utm_campaign=rss&redirCanon=1
2http://www.harvestplus.org/content/faq
3http://www.medicinalfoodnews.com/vol01/issue2/japan
4https://www.drfuhrman.com/library/article19.aspx
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Nutraceuticals: The future of intelligent food | 7
14
EUROPE
%
22 JAPAN
%
30
U.S.
%
34
REST OF
%
THE WORLD
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8 | Nutraceuticals: The future of intelligent food
A snapshot of global
regulations
EU
United States A complex range of regulations applies to
nutraceuticals in the EU, depending on the
In the U.S., nutraceuticals mainly come
product type. These are mainly overseen by
under the category of vitamins and dietary
the European Food Safety Authority (EFSA),
supplements. A range of regulations apply,
which also evaluates claims and has a public
notably the Dietary Supplement Health and
Education Act (DSHEA) from 1994, which Register of Nutrition and Health Claims.
covers dietary supplements, the Federal If a product is not on this certified list it
Food Drug and Cosmetic Act, which covers cannot be used until approved for inclusion
all foods and food additives, and Good following detailed scientific testing by the
Manufacturing Practice regulations from company and subsequent review by the
2007. Under these the manufacturer: EFSA. The EFSA also sets maximum and
minimum levels of ingredients to be added
is responsible for ensuring the safety of
to supplements. Labels cannot contain
supplements it makes or distributes
claims that their product will diagnose, cure,
must make no false or misleading claims mitigate, treat or prevent a disease; nutrition
and health claims must be authorized at an
cannot claim the product will diagnose,
EU level.
cure, mitigate, treat or prevent a disease
Between 2008 and 2011 the EFSA evaluated
must notify the FDA if wishing to use
any ingredient not sold before October 2,758 food-related general health claims
15 1994, with the notification containing to see if they were supported by scientific
information the manufacturer/distributor evidence. Only around 10 percent of the
has used to certify the products safety claims could be substantiated.
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Nutraceuticals: The future of intelligent food | 9
China
China has a lengthy and costly registration process, with
three main entities involved in policing the industry. The
State Food and Drug Administration (SFDA) is in charge
of dietary supplements and registration. The Ministry of
Health (MOH), oversees the SFDA and the approval of
new novel food ingredients. Finally, the Administration of
Quality Supervision Inspection and Quarantine (AQSIQ)
controls all the imports and exports.
Japan
Foods with nutrient function
claims are not heavily regulated
and simply must satisfy the
standards for the minimum and
maximum daily levels of twelve
vitamins and five minerals.
Foods for specified health uses
India (FOSHU) require pre-marketing
The manufacture, storage, distribution, approval, and refer to products
sale and import of nutraceuticals in containing dietary ingredients
India are regulated under the Food that have reported beneficial
Safety and Standards Act (FSSA). The physiological effects and
required manufacturing oversight is less promote health. Disease risk
strong than for pharmaceuticals, which reduction claims are not allowed.
may impact Indian producers ability to
produce nutraceuticals for export.
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10 | Nutraceuticals: The future of intelligent food
Technological prowess and marketing smarts are not A number of recent acquisitions of food and beverage
all thats required to build a nutraceuticals powerhouse. companies are aimed at securing stable, high-quality
Manufacturers of functional foods must also pay close supplies of raw materials. Having acquired nutritional
attention to every stage in the supply chain. With supplements manufacturer Complan Food UK in 20112, for
increasing consumer concerns about food safety, the example, Danone purchased a 40 percent stake in Kenyas
quality of the raw materials used to create nutraceutical Brookside Dairy in 2014, which has around 140,000 milk
supplements have come under intense scrutiny, so farms in East Africa3. Such vertical integration not only
companies must consider carefully how to access and gives greater certainty of supply; it also lays a foundation
assure supplies of essential ingredients or flavorings. for developing new uses of existing materials, or to
produce new, related ingredients.
In the U.S., nutraceutical companies collect detailed
information about suppliers using the Standardized Consumer perception is also essential. Starbucks,
Information on Dietary Ingredients protocol1, which the coffee company, had to reformulate some of their
provides data on the (wild or cultivated) sources of beverages when consumers reacted to the use of natural
ingredients, the methods of agricultural process and cochineal extract. This extract, derived from an insect, was
manufacture, and of sterilization. Supply chain risks can be used to provide their products a red color. Cochineal was
high: sun-dried materials, for example, may be subject to replaced with lycopene, a natural, tomato-based extract,
the growth of mold or even toxins. in the strawberry sauce (base) used in their Strawberries
& Crme Frappuccino blended beverage and Strawberry
Banana Smoothie.
1http://www.npainfo.org/NPA/Communications/SIDI.aspx
2http://www.pmmireports.org/pmmi/2011/07/01/danone-acquires-complan-food-uk/
3http://www.bloomberg.com/news/2014-07-18/danone-buys-40-of-kenya-s-brookside-to-expand-african-footprint.html
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12 | Nutraceuticals: The future of intelligent food
Investing in nutraceuticals
Faced with technological, regulatory and logistical The sale of product lines creates new opportunities
challenges, food and pharmaceuticals companies are for the acquirer, and the fragmented structure of the
taking advantage of the growth of nutraceuticals in nutraceuticals industry suggests that there will be
different ways. Some are investing in start-ups. Nestle many mergers in the future. In April 2014, Integrity
has set up a venture capital fund with the aim of investing Nutraceuticals and Cornerstone Research & Development
in early-stage nutraceuticals businesses. The fund takes merged7, combining the formers capability in the
varying stakes in these entities and then tries to buy a manufacture of powder and capsule products with the
majority share at a later date, should the start-up prove latters production of vitamin supplements. In June 2014,
successful. On the pharmaceuticals side, Alliance Boots Spanish pharmaceuticals multinational Laboratorio Reig
(now part of Walgreens Boots Alliance1, a global pharmacy Jofre merged with nutritional supplements specialist
chain created at the end of 2014) launched a specialized Natraceutical8. The new entity plans to sell its science-
investment fund, B&B Investment Partners, which focuses based nutritional products through its medical channels,
on small- and medium-sized consumer brand businesses although there is no apparent move to enter consumer
within health, wellness, beauty and personal care. One markets.
of its first deals, announced in November 2014, was the
Such mergers are small in comparison with the size of
US$30 million acquisition of PhD Nutrition, a leading
the global nutraceuticals market, but they are a harbinger
producer of protein powder and nutrition bars2.
of bigger transactions to come. It only takes one sizeable
Other companies have been re-balancing their product acquisition to change the dynamics of the industry, and
portfolio, abandoning companies that dont fit their then other big companies in the field will be forced to
strategy. In 2013, GSK sold its nutritional drinks brands respond. In a rapidly changing market, it may be better
Lucozade and Ribena to Japans Suntory3. More recently to take the initiative rather than wait for others to make
Nestle unloaded its sports nutrition PowerBar brand to their move. Whether or not the first company to move,
cereal maker Post Holdings of the U.S.4 in order to focus deal making skills of a high order are needed to gain the
on a few winning products. Unilever said in July 2014 that advantage, as companies scramble for the choicest assets.
it sold its Slim-Fast diet unit to Kainos Capital, a private
equity firm5. Danone, by contrast, said in December 2014
that it would keep its medical nutrition business, ending
months of speculation that it would sell the unit6.
1http://www.walgreensbootsalliance.com/
2 B&B Investment Partners flexes muscles with PhD Nutrition deal, City A.M., 17 November 2014
3https://www.gsk.com.au/media-centre_detail.aspx?view=637
4http://www.nestle.com/media/pressreleases/allpressreleases/nestle-sells-powerbar
5http://www.unilever.com/mediacentre/pressreleases/2014/UnileversellsSlimFasttoKainosCapital.aspx
6http://www.ft.com/intl/cms/s/0/37f5b7aa-8154-11e4-b956-00144feabdc0.html#axzz3OdO0fJS0
7http://higgrowth.com/news/release/734
8http://natraceutical.com/images/descargas/eng/investors/relevant_facts/2014-6-26-HR-de-NdP-Fusion-NTC-LRJ-ing-def.pdf
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200
Number of deals
150
100
50
2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012
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14 | Nutraceuticals: The future of intelligent food
FOOD NUTRACEUTICALS
ELLAS
Child/baby
KITCHEN CHOCO-MILK
PEPTO
Sports/energy LUCOZADE
HORLICKS
Brain/mental
SODA-LO
OAT WELL
Cardio/heart
YAKULT
Joint/bone ACTIVIA
TO
Gastrointestinal
Weight management
HERBALIFE
PEPSI
SPECIAL
Diabetes
Other
GENVIDA LYCORED
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16 | Nutraceuticals: The future of intelligent food
Characteristics of success:
Daring to win
To succeed in the brave new world of nutraceuticals,
KPMG believes that companies will have to excel in six areas:
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Nutraceuticals: The future of intelligent food | 17
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KPMGs nutraceutical credentials
KPMGs global network of member firms work with We help clients with issues such as:
some of the worlds biggest companies across the managing a product lifecycle
pharmaceuticals, food and nutraceuticals sectors
assessing risks across an R&D portfolio
and can help you create an effective strategy for
this fast-growing market. Our expertise spans building research partnerships with academia
key areas such as product management, R&D and other specialists
innovation, sales and marketing, market planning, structuring and incentivizing sales and marketing
mergers and acquisitions, and joint ventures. teams
new market entry planning
planning, funding and implementing mergers
and acquisitions, including financial due
diligence.
Contact us
Chris Stirling Chris Stott
Global Chair, Life Sciences Head of Food and Drink for the UK
T: + 44 (0)20 7311 8512 T: + 44 (0)113 231 3825
E: christopher.stirling@kpmg.co.uk E: christopher.stott@kpmg.com
www.kpmg.com
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