Fantastic Voyage - The Cell Cycle - Just V.O.

Written By

Ruth Cann

The Cell Cycle

Address
Phone Number
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INT. SCENE 1

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SCENE 2

V.O.
"This is a cell."
SCENE 3

V.O.
"You and I are made out of
around...(pause)...1 trillion
cells!"
Pause...
"That's a lot!"
SCENE 4

V.O.
"Cells help regenerate our skin,
bone tissues and organs."
SCENE 5

V.O.
"Cells come in numerous shapes and
sizes depending on their role."

SCENE 6

V.O.
"Our cells replicate. To do this,
they go through a cycle.

SCENE 7
V.O.
"The cell cycle comprises four
different stages."

V.O.
"The Growth Phase - known as the

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(G1 Phase)."

V.O.
"The Synthesis Phase - known as the
(S Phase)."

V.O.
"The cell's final growth stage and
preparation for mitosis - known as
the (G2 Phase)."

V.O.
"And finally Mitosis - known as the
(M Phase)."
SCENE 8

V.O.
"Throughout this cycle there are
three checkpoints."

Pause...

"Checkpoint one is towards the end

of the G1 phase."

V.O.
"Checkpoint two comes at the end of
the G2 phase."

V.O.
"And Checkpoint three at the end
of Metaphase during Mitosis."
SCENE 9

V.O.
"If a cell fails to make the
grade..."

V.O.
"it will die - either by being
killed or self-termination"
Pause
"This is a Skin Cell"

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(CONT'D)
V.O.
"A Skin Cell should look a lot like
this one right here."

V.O.
"Inside its centre is a Nucleus, and
inside the nucleus you'll find..."

V.O.
"Twenty-three pairs of
Chromosomes."

V.O.
"Each Chromosome comprises two
Sister Chromatids."

SCENE 10
V.O.
"Chromosomes are made from your DNA
-"

V.O.
" - and histone proteins."

V.O.
"This combination gets compacted
together to create your
chromosomes."

SCENE 11
-
SCENE 12 V.O.
"To the right is a cell."

V.O.
"And below, a chart showing you the
cell-cycle.
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SCENE 13

V.O.
"During G1 - the Gap 1 Phase - all
cytoplasmic components in the cell
are duplicated ."
SCENE 14

V.O.
"The cell is then checked before
moving to the..."

V.O.
"S Phase, or the Synthesis Phase.
This is where the DNA replicates."
SCENE 15

V.O.
"Next is the G2 Phase, or the Gap 2
Phase."

V.O.
"This is when enzymes needed for
cell division are created."

SCENE 16
V.O.
"The cell is now checked for a
second time."

SCENE 17
V.O.
"Now the cell is ready for the
final phase called mitosis, or the
(M Phase)."

V.O.
"During this phase there follows
four different stages."

SCENE 18
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V.O.
"The first is the Prophase -"

V.O.
"- where the DNA and histone
proteins combine to create
chromosomes."
SCENE 19

V.O.
"It's during this stage the
centrioles move to the opposite
poles and tubules extend."

V.O.
"The nuclear membrane breaks down -
meaning the tubules can attach to
the chromosomes."
SCENE 20

V.O.
"The second phase, called the
Metaphase, sees the chromosomes
lined up in row."
SCENE 21

V.O.
"The cell then goes through its
final check."
SCENE 22

V.O.
"Anaphase is when the chromosomes
are separated."
SCENE 23

V.O.
"The final stage is called the
Telophase."

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V.O.
"A new nuclear envelope appears
around the separated chromosomes.
Once contained, the chromosomes
uncoil once more into long strings
of DNA."

SCENE 24
V.O.
"Once the cell has separated you now
have two identical daughter cells."
Pause...
" A full cell cycle can take around
ten to twenty hours to complete,
depending on its job. Cells also
vary as to how many times they can
replicate."

SCENE 25
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