Functional Group identification of organic compounds

Academic Paper Reoport

By
Chanisara Wanna

Purpose of Compound

Aspirin have several benefits, thus they are mostly used in cardiovascular disorders
and even in the treatment of cancer. In the meantime, it is also used as medicines that helping
the body to lessen doses has adverse effect,especially on the digestive section: dyspeptic
symptoms, peptic ulcers, gastrointestinal erosions, overt bleeding or perforation. However,
the studied said in vitro that aspirin causes oxidative stress to cells. Other works have
revealed that various factors, such as oxygen-derived free radicals and inflammatory
cytokines are associated with the aspirin-induced gastric mucosal damage. Hence, attempts
have been made to develop a risk-free dose, or a coated and buffered aspirin to mitigate the
injury.

General Information
- The molecular formula for acetylsalicylic acid, more commonly known as
aspirin, is C9H8O4.
- Aspirin is the medicine that used to reduce the pain in the treatment of mild to
moderate pain
- Aspirin is a salicylate (sa-LIS-il-ate). The working process of the aspirin, the
substance in the the body that caused pain, fever, and inflammation will be reduced by
this medicine.
 - If you having bleeding disorder or if you have been stomach bleeding or
intestinal bleeding you will be prohibited to use this medicine. Moreover, the patients
that allergic to Advil, Motrin, Aleve, Orudis, Indocin, Lodine, Voltaren, Toradol,
Mobic, Relafen, Feldene, and other cannot taking aspirin
- Aspirin will cause Reye's syndrome if you have this following diseases: fever,
flu symptoms or chickenpox, especially for the teenagers and children.

Properties

Chemical Properties

Property Name Property Value

Mole Weight 180.159 g/mol

Hydrogen Bond Donor Count 1

Hydrogen Bond Acceptor Count 4

Rotatable Bond Count 3

Complexity 212

Exact Mass 180.042 g/mol

Formal Charge 0

physical properties
State: Solid
Properties: Odorless, colorless to white, crystal-line powder.
Boiling Point: 284 F at 760 mm Hg (decomposes)275 F (NTP, 1992)
Melting Point: 275 F (NTP, 1992)
Water Solubility: 4600 mg/L (at 25 C)

References
 1. Biological properties of citral and its potential protective effects against
cytotoxicity caused by aspirin in the IEC-6 cells. (n.d.). Retrieved May 22, 2017, from
http://www.sciencedirect.com/science/article/pii/S0753332216318030
2. Aspirin Uses, Dosage, Side Effects & Interactions. (n.d.). Retrieved May 22,
2017, from https://www.drugs.com/aspirin.html
3. Aspirin. (n.d.). Retrieved May 22, 2017, from
https://pubchem.ncbi.nlm.nih.gov/compound/aspirin#section=Boiling-Point