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Penicillin

Purpose and Application

Penicillin is a group of antibiotics derived from the Penicillium fungi. Penicillin is effective
against bacterial infections as it kills bacteria by interfering with the ability to synthesize cell wall. It
was historically important discovery, as it was the first drug effective against many previously serious
diseases such as syphilis and Staphylococcus infection. [1]

Penicillin power can be diluted with sulfanilamide to used to cure burns. It can prevent the
development of infection at early stage and for eradicating it at later stage. [2]
There are a few types of penicillins, each used to treat various types of contaminations.
For example
skin infections
dental infections
ear infections
respiratory tract infections
urinary tract infections
gonorrhea
and other infections brought on by bacterias
These medications won't work for olds, flus, and other infections caused by viruses. [3]
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Physical and Chemical Properties [4]

PropertyName PropertyValue

MolecularWeight 357.38g/mol

HydrogenBondDonorCount 2

HydrogenBondAcceptorCount 5

RotatableBondCount 4

Complexity 530

CACTVSSubstructureKeyFingerprint
AAADceB7OCBAAAAAAAAAAAAAAABYA
WAAAAAwAAAABYAAAAABAAAAHgQQC
AAADCjF2ASyCIPAAgiIAiHSGAACAABgAB
AIiIGIAIgKYDqglTGUYAAklgC4iAcYiICOAA
AAAAAAAAAAAAAAAAAAAAAAAAAA

TopologicalPolarSurfaceArea 112A^2

MonoisotopicMass 357.088g/mol

ExactMass 357.088g/mol

CompoundIsCanonicalized true

FormalCharge 1

HeavyAtomCount 24
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DefinedAtomStereocenterCount 0

UndefinedAtomStereocenterCount 3

DefinedBondStereocenterCount 0

UndefinedBondStereocenterCount 0

IsotopeAtomCount 0

Covalently-BondedUnitCount 2
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References

[1] What is penicillin used for. (2010, October 25). Retrieved May 25, 2017, from
http://ic.steadyhealth.com/what-is-penicillin-used-for

[2] Thompson C.W., (1946). Topical Application of Penicillin: Solution, Gentian-Violet and
Heat in the Treatment of Extensive 1st and 2nd Degree Burns in Children. Retrieved May 22, 2017,
from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2616807/pdf/jnma00653-0012.pdf

[3] Penicillins. (n.d.). Retrieved May 25, 2017, from

http://www.encyclopedia.com/medicine/drugs/pharmacology/penicillin

[4] Penicillin. (n.d.). Retrieved May 25, 2017, from

https://pubchem.ncbi.nlm.nih.gov/compound/54607813#section=Computed-Properties&fullscreen=tr
ue
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