HISTOLOGY OF

THE GASTRO-
INTESTINAL
TRACT
Part 1: Tongue and Esophagus

Kriziaoumo P. Orpia, RMT, MED-1C

Batch 2018
FOLIATE PAPILLAE

TASTE BUDS

LAMINA PROPRIA
Note from the Previous Practical
Cell involved in Taste Sensation
Gustatory Receptor Cells
NOT involved:
Basal Cells
Sustentacular Cells (supporting cells)
The Tongue Topography
Dorsal Surface of the Tongue
F- Fungiform p.
Fl- Filiform p.
SS- Strat. Squamous E.
CT- Lamina Propia
/Connective Tissue
Vallate Papillae
Located bet. Body and
the root of the tongue

SS- Strat. Squamous e.

TB- Taste Bud
GL- Salivary Glands
CT- Connective Tissues
Foliate Papillae
As similar to the FIRST
SLIDE
ESOPHAGUS
 Esophagus
Layers

Stratified Squamous e.
Lamina Propria
Muscularis mucosae
SUBMUCOSA

INNER CIRCULAR M.

Outer Longitudinal M.

ADVENTITIA
Notes for the Practicals
Components of the Muscularis Externa
Inner circular
Outer Longitudinal
Submucosa, sometimes have Fat Cells
Cardiac Esophageal Glands Mucous/ @ Lamina propria
Esophageal Glands Proper- Mucous/ @Submucosa
Pacemaker of GIT- IC of Cajal

Not mentioned by Dr. Kit but nice to know

Vascular Plexus- Hellers Plexus

QUESTION: What is the Histological
Division of this SLIDE of the
Esophagus? (UPPER/MIDDLE/LOWER

SUBMUCOSAL
GLANDS/ESOPHAGEAL
GLANDS PROPER
MUSCULATURE OF ESOPHAGUS
UPPER INNER: STRIATED M.
THIRD OUTER: STRIATED M.

INNER: SMOOTH M. MIDDLE

OUTER: STRIATED M. THIRD

LOWER INNER: SMOOTH M.

THIRD OUTER: SMOOTH M.

NOTE: ORIENTATION STILL APPLIES ICOL

QUESTION: What is the Histological
Division of this SLIDE of the
Esophagus? (UPPER/MIDDLE/LOWER
UPPER THIRD

SUBMUCOSAL
GLANDS/ESOPHAGEAL
GLANDS PROPER

striated
striated
MEDITATE ON THE LAYERS HERE
GASTROESOPHAGEAL
JUNCTION
NOTES:
CG- Cardiac Gland
ECG- Esophageal Cardiac Gland
CARDIA OF STOMACH

DISTAL ESOPHAGUS (SS)

GASTRIC PIT

LAMINA PROPRIA

CG
CG
SMOOTH MUSCLE

ECG

SUBMUCOSA
FROM JUNQUIERA
E- esophagus
C- Cardia
CG-cardiac g.
ECG-esophageal
cardiac g.
GP- Gastric Pit

Note: basta
nearest the end
of the gastric pits
are CG not ECG

From Ross (Gastroesophageal
Junction)
What is the histological significance
of BARETTs Esophagus?
The Stratified Lining of the esophagus undergoes
MEPLASIA becoming Simple Columnar e.
Metaplasia is prone to develop into dysplasia-
adenocarcinoma of the Esophagus
References:
Junqueiras Basic Histology Text and Atlas by
Anthony Mescher 12th Edition
Histology A Text and Atlas Histology by Ross 6th
Edition

Note: Teeth not included

HISTOLOGY OF
THE GASTRO-
INTESTINAL
TRACT
Part 2: Stomach

Kriziaoumo P. Orpia, RMT, MED-1C

Batch 2018
Recap on the GE Junction

ESOPHAGUS CARDIA
Stratified Squamous e. Simple Columnar e.
Acid sensitive Acid Resistant
Glands in proximity:
Glands in proximity: Cardiac Glands
Esophageal Cardiac Mucus
Glands SECRETES GASTRIN
Mucus GATRIC MOTILITY
Principal glands secreting
Support to Cardiac mucus
Glands Nearest to the terminal
end of GASTRIC PITS
NOTES:
CG- Cardiac Gland
ECG- Esophageal Cardiac Gland
CARDIA OF STOMACH

DISTAL ESOPHAGUS (SS)

GASTRIC PIT

LAMINA PROPRIA

CG
CG
SMOOTH MUSCLE

ECG

SUBMUCOSA
 Cardia
GASTRIC PITS/ FOVEOLAE

GASTRIC/OXYNTIC GLANDS

CARDIAC GLANDS
Glands in the Cardia:
OXYNTIC GLAND/GASTRIC
CARDIAC GLAND GLANDS
Simple tubular g. Simple tubular g.
Limited only in the Abundant in the stomach
transition area (GE Secretes gastric juice
junction)
4 types of Cell population
Secretes Mucus and BLUE CELL (Chief Cells)
GASTRIN PINK CELL (parietal Cells)
1 type of cell population MUCUS NECK CELLS
Mucus Cell? research mo na lang UNDIFFERENTIATED STEM
CELLS
On more thing:
Esophagus has 1 (longitudinal) layer of Muscularis
mucosae but when it reached the stomach ;
It becomes 2 (inner circular/outer longitudinal)
Iba po ito sa muscularis externa
One more look
Cardiac(left)/Gastric (right)

Cardiac glands
usually seen
along shallow
FOVEOLAE,unlike
Gastric Glands
Fundus and
Corpus(Body)
Fundus
-(Fundic Glands/Gastric Glands)
 Parietal Cells- concentric nucleus (nasa gitna!)
Chief- eccentric nucleus (gumigilid)
BOOODY (BODY)
Masinsinang opinion (Malabo
man mata ko o hindi)
I know guys, its very difficult to tell but as long as it
resembles a LONG TUBULAR GLAND located in a
VERY CROWDED LAMINA PROPRIA

BEST CHANCE IS ITS A FUNDIC GLAND

PERO PLAY SAFE ISASAGOT KO GASTRIC GLAND
PYLORIC REGION
 Pyloric Region Deep foveolae

Deep foveolae
Pyloric Gland (longitudinal cut)

Muscularis mucosae

Pyloric Gland (transverse cut)

Lamina Propria
Pyloric Region
To Help
Visualize
P.261 of Junquiera
Clinical Correlation
References
Junqueiras Basic Histology Text and Atlas by
Anthony Mescher 12th Edition
Histology A Text and Atlas Histology by Ross 6th
Edition
Bloom and Fawcetts Histology
Practical Illustrated Histology by Radcliffe
Lippincotts Atlas to Histology by Dongmei Cui
diFiores Atlas to Histology with Clinical Correlations