ABSTRAK

Latar Belakang. BPH adalah pembesaran kelenjar dan jaringan seluler kelenjar prostat yang
berhubungan dengan perubahan endokrin berkenaan dengan proses penuaan. Kelainan yang
sering dijumpai pada prostat adalah Benign Prostat Hyperplasia. Penyakit-penyakit tersebut
dialami oleh 50% pria yang berusia lebih dari 60 tahun keatas. Antigen Spesific Prostat
digunakan dalam penegakan diagnosis dan manajemen kanker prostat. PSA merupakan produk
epitel kelenjar dan normalnya disekresikan kedalam air mani. Kadar serum PSA mengalami
kenaikan yang lebih rendah pada hyperplasia nodular jinak dibandingkan pada kanker prostat.
Metode desain penelitian ini menggunakan rancangan cross sectional. Penelitian ini dilakukan di
RSUD Pirngadi Medan periode 2014-2015. Sample penelitian ini sebanyak 146 orang,
pengambilan sample dari rekam medik.

Tujuan. Untuk mengetahui hubungan peningkatan prostate specific antigen dengan terjadinya
benign prostate hyperplasia. Hasil. Terdapat hubungan usia dengan penderita BPH pada RSUD
Pirngadi Medan periode 2014-2015 dengan nilai p = 0,030 (p<0,05) Kesimpulan. Adanya
hubungannya usia dengan terjadinya BPH di RSUD Pirngadi Medan periode 2014-2015.

Kata kunci: BPH, usia,

 ABSTRACT

Background. BPH is the enlargement of the prostate gland and cellular networks associated with
endocrine changes with respect to the aging process. The common disorder of the prostate are
benign prostatic hyperplasia. Those diseases were experienced by 50% of men more than 60
years. Prostate Specific Antigen are used in the diagnosis and management of prostate cancer.
PSA is a product of glandular epithelium and is normally secreted into the semen. Serum levels
of PSA increase is lower in comparison to the benign nodular hyperplasia of prostate cancer.
Methods. The design of this study using cross sectional design. This research was conducted in
Rumah Sakit Pirngadi Medan on 2014-2015. The sample of this study was 146 people, and
taking from medical records.

Objective. To determine the relationship of increase in prostate specific antigen with the
occurrence of Benign Prostate Hyperplasia. Results. There is a relationship of age with BPH
patients at Rumah Sakit Pirngadi period 2014-2015 with a value of p = 0.030 (p <0.05)
Conclusion. There is a relationship of age with the BPH occurrence in Rumah Sakit Pirngadi
Medan period 2014-2015.

Keywords: BPH, age

 DAFTAR RIWAYAT HIDUP

BIODATA
Nama : Cut Mutia Sari

Tempat/Tanggal Lahir: Medan, 02 Januari 1995

Agama : Islam

Jenis Kelamin : Perempuan

Suku : Aceh

Golongan Darah :A

Alamat : Jln. T.Sari Pasar 2 Komp. Taman Perkasa Indah (TPI) Blok. F2

RIWAYAT PENDIDIKAN
1. SD-N 94 Medan Lulus 2006
2. SMP-N 21 Medan Lulus 2009
3. SMA Kartika I 1 Medan Lulus 2012
4. Prodi S1 Kedokteran Islam Sumatera Utara Angkatan 2012

RIWAYAT ORGANISASI
1. TBM FK UISU
 MASTER DATA

Crosstabs
Notes
Output Created 11-FEB-2016 19:17:18
Comments
Active Dataset DataSet0
Filter <none>
Weight <none>
Input
Split File <none>
N of Rows in Working 300
Data File
User-defined missing values are
Definition of Missing
treated as missing.
Statistics for each table are based on
Missing Value Handling
all the cases with valid data in the
Cases Used
specified range(s) for all variables in
each table.
CROSSTABS
/TABLES=pekerjaan usia BY
penderita
Syntax /FORMAT=AVALUE TABLES
/STATISTICS=CHISQ
/CELLS=COUNT
/COUNT ROUND CELL.
Processor Time 00:00:00.03
Elapsed Time 00:00:00.03
Resources
Dimensions Requested 2
Cells Available 174734

Case Processing Summary

Cases
Valid Missing Total
N Percent N Percent N Percent
pekerjaan * penderita 300 100.0% 0 0.0% 300 100.0%
BPH
usia penderita * penderita 300 100.0% 0 0.0% 300 100.0%
BPH

2. pekerjaan * penderita BPH

Crosstab
Count
penderita BPH Total
tidak ya
Bekerja 119 101 220
pekerjaan
tidak bekerja 35 45 80
Total 154 146 300
3.
Tidak ada hubungan karena > 0,05
4.
Chi-Square Tests
Value df Asymp. Sig. Exact Sig. (2- Exact Sig. (1-
(2-sided) sided) sided)
Pearson Chi-Square 2.511a 1 .113
Continuity 2.114 1 .146
b
Correction
Likelihood Ratio 2.514 1 .113
Fisher's Exact Test .119 .073
N of Valid Cases 300
a. 0 cells (0.0%) have expected count less than 5. The minimum expected count is 38.93.
b. Computed only for a 2x2 table

5. usia penderita * penderita BPH

Crosstab
Count
penderita BPH Total
tidak ya
41-59 51 32 83
usia penderita
> 60 103 114 217
Total 154 146 300
 Ada hubungan karena < 0,05

Chi-Square Tests
Value df Asymp. Sig. Exact Sig. (2- Exact Sig. (1-
(2-sided) sided) sided)
Pearson Chi-Square 4.697a 1 .030
Continuity 4.154 1 .042
b
Correction
Likelihood Ratio 4.733 1 .030
Fisher's Exact Test .039 .021
N of Valid Cases 300
a. 0 cells (0.0%) have expected count less than 5. The minimum expected count is 40.39.
b. Computed only for a 2x2 table

Frequencies

Notes
Output Created 11-FEB-2016 19:17:38
Comments
Active Dataset DataSet0
Filter <none>
Weight <none>
Input
Split File <none>
N of Rows in Working 300
Data File
User-defined missing values are
Definition of Missing
treated as missing.
Missing Value Handling
Statistics are based on all cases with
Cases Used
valid data.
FREQUENCIES
Syntax VARIABLES=pekerjaan usia
/ORDER=ANALYSIS.
Processor Time 00:00:00.02
Resources
Elapsed Time 00:00:00.02
 Statistics
pekerjaan usia penderita
Valid 300 300
N
Missing 0 0

Frequency Table
pekerjaan
Frequency Percent Valid Percent Cumulative
Percent
bekerja 220 73.3 73.3 73.3
Valid tidak bekerja 80 26.7 26.7 100.0
Total 300 100.0 100.0

usia penderita
Frequency Percent Valid Percent Cumulative Percent
41-59 83 27.7 27.7 27.7
Valid > 60 217 72.3 72.3 100.0
Total 300 100.0 100.0

*tidak bekerja = tidak bekerja, pensiunan, pensiunan

*bekerja = selain ketiga diatas.