Virology Exam 2010 Selected Questions and Answers

1. A 30 yr. old man has a blood test that is HBsAg negative, Anti-HBc
negative, and anti-HBs positive. He most likely
a. is immune to HBV
b. is suffering an acute infection of HBV
c. is suffering a chronic infection HCV
d. is infected with HDV
e. has contracted an STD from the Immunology department of his
university

9. Which one of the following statements about genital herpes is least accurate?
a. Acyclovir reduces the frequency of recurrent disease episodes by
eradicating latently infected cells.
b. Genital herpes can be transmitted in the absence of apparent lesions.
c. Herpes simplex virus can be isolated from genital lesions by tissue culture.
d. Primary disease episodes are generally more severe than recurrent
episodes.
e. Genital herpes can be caused by both HSV-1 and HSV-2.
15. Genotype resistance involves cell culturing the virus with anti viral
drugs.
a. True
b. False

27. An adult exposed to a child with chicken pox will experience herpes
zoster
a. True
b. False

35. Which of the following sentences describing the structure of viruses is

correct (the most comprehensive correct answer)
a. A helical viral capsid can be assembled in the absence of the viral nucleic acid.
b. An icosahedral viral capsid can be assembled in the absence of the viral
nucleic acid.
c. Both helical and icosahedral capsids can be assembled in the absence of a viral
nucleic acid.
d. All virus families have either a helical or an icosahedral capsid.

36. Cells from a transplanted kidney from a CMV positive patient (in
the latent stage) can undergo reactivation in the recipient.
a. True
b. False

41. Which of the following viruses can be sexually transmitted?

a. Hepes
b. HIV
c. Human papiloma virus
d. Hep B
e. all of the above viruses can be sexually transmitted

53. Which one of the following statements about genital herpes is least
accurate?
a. Acyclovir reduces the frequency of recurrent disease episodes
by eradicating latently infected cells.
b. Genital herpes can be transmitted in the absence of apparent lesions.
c. Herpes simplex virus can be isolated from genital lesions by tissue
culture.
d. Primary disease episodes are generally more severe than recurrent
episodes.
e. Genital herpes can be caused by both HSV-1 and HSV-2.