Antipsychotics MCQs

Neuroleptics are used to treat which of the

following?
A. Neurosis
B. Psychosis
C. Narcolepsy
D. Parkinsons
 Most antipsychotic drugs do which of the
following?
A. Strongly block D2 receptors
B. Stimulate postsynaptic D2 receptors
C. Block NMDA receptors
D. Stimulate the 5-HT2 receptors
 Hyperprolactinemia is caused by blockade of
dopamine in?
A. Chemoemetic Trigger Zone
B. The pituitary
C. The extrapyramidal system
D. The mesolimbic system
 Parkinsonian symptoms and tardive dyskinesia
are caused by blockade of dopamine in?
A. The nigrostriatal system
B. The mesolimbic system
C. The chemoreceptor trigger zone
D. The tuberoinfundibular system
 Extrapyramidal reactions can be treated by?

A. Levodopa
B. Benztropine
C. Bromocriptine
D. Dopamine
 Which of the following drugs is a typical
antipsychotic?
A. Clozapine
B. Quetiapine
C. Haloperidol
D. Olzanzepine
 Tardive dyskinesia is the result of ?
A. Degeneration of Dopaminergic fibres
B. Hyperactive dopaminergic state
C. Super sensitivity of Muscarinic receptors
D. Low sensitivity of histamine receptors
 Which of the following drugs is a
phenothiazine?
A. Ziprasidone
B. Risperidone
C. Chlorpromazine
D. Clozapine
The strong antiemetic effect of phenothiazines
is due to?
A. Dopamine receptor blockade
B. Muscarinic receptor blockade
C. Histamine receptor Blockade
D. A and B
E A and C
 Parkinsonism, tardive dyskinesia, galactorrhea
are adverse effects of which of the following?

A. Haloperidol
B. Clozapine
C. Chlorpromazine
D Risperidone
 Which of the following antipsychotics can
cause retinal damage?
A. Haloperidol
B. Droperidol
C. Fluphenazine
D. Thioridazine
 Which of the following is true for clozapine?

A. Potent anticholinergic activity

B. Has high affinity for D1 and D3 receptors
C. Can cause agranulocytosis
D. Can antagonize benzodiazpines
 Lithium overdose can best be treated with
which of the following?
A. Diuretic
B. Induce vomiting
C. Propranolol
D. Hemodialysis
If given in the first trimester, which tissue fetal
abnormalities would be expected?
A. Hippocampus
B. Major blood vessels
C. Liver
D. Cerebral cortex
 Which of the following is a butyrophenone?

A. Droperidol
B. Thioridazine
C. Sertindole
D. Fluphenazine
 The anti-emetic effect of prochlorperazine is
due to DA receptor blockade in?
A. CTZ
B. H1 receptors in the stomach
C. Vomiting Center
D. All of the above
 Phenothiazines are able to do which of the
following?
A. Decrease appetite
B. Decrease prolactin
C. Increase salivation
D. Block DA, H1 and M receptors
 Which of the following can block alpha1
receptors?
A. Haloperidol
B. Chlorpromazine
C. Clozapine
D. Resperidone