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coordination between the bladder muscle (detrusor) and the urethra. With normal urination, the urethra
relaxes and opens when the bladder muscle contracts allowing urine to pass out of the body freely. In
those voiding dysfunction, the urethra does not relax when the bladder muscle contracts making it
difficult for urine to pass. Both neurogenic and non-neurogenic disorders can cause adult voiding
dysfunction. The micturition (voiding or urination) process involves several highly coordinated
neurologic responses that mediate bladder function. A functional urinary system allows for appropriate
bladder filling and complete bladder emptying. If voiding dysfunction goes undetected and untreated,
the upper urinary system may be compromised. Chronic incomplete bladder emptying from poor
detrusor pressure results in recurrent bladder infection. Incomplete bladder emptying due to bladder
outlet obstruction (such as benign prostatic hyperplasia), causing high-pressure detrusor contractions,
can result in hydronephrosis from the high detrusor pressure that radiates up the ureters to the renal
pelvis.
CAUSES
Voiding dysfunction maybe caused by nerve dysfunction, non-relaxing pelvic floor muscles or both if the
problem stems from a neurological disorder or spinal injury it is called detrusor-sphincter dyssynergia.
If no neurological disorder or injury is present, it is referred to as pseudodyssynergia
SYMPTOMS
Timed voiding involves establishing a set voiding frequency (such as every 2 hours if incontinent
episodes
tend to occur 2 or more hours after voiding). The individual chooses to void by the clock at the given
interval while
awake, rather than wait until a voiding urge occurs.
Prompted voiding is timed voiding that is carried out by staff or family members when the individual
has cognitive
difficulties that make it difficult to remember to void at set intervals. The caregiver checks the patient to
assess if he
or she has remained dry and, if so, assists the patient to use the bathroom while providing positive
reinforcement
for remaining dry.
Habit retraining is timed voiding at an interval that is more frequent than the individual would usually
choose. This technique helps to restore the sensation of the need to void in individuals who are
experiencing diminished sensation
of bladder filling due to various medical conditions such as a mild cerebrovascular accident (CVA).
Bladder retraining, also known as bladder drill, incorporates a timed voiding schedule and urinary
urge inhibition exercises to inhibit voiding, or leaking urine, in an attempt to remain dry for a set time.
When the first timing interval
is easily reached on a consistent basis without urinary urgency or incontinence, a new voiding interval,
usually
10 to 15 minutes beyond the last, is established. Again, the individual practices urge inhibition exercises
to delay
voiding or avoid incontinence until the next preset interval arrives. When an acceptable voiding interval
is reached, the patient continues that timed voiding sequence throughout the day.
Neuromodulation
Neuromodulation via transvaginal or transrectal nerve stimulation of the pelvic floor inhibits detrusor
overactivity and hypersensory bladder signals and strengthens weak sphincter muscles.
SURGICAL MANAGEMENT
Surgical correction may be indicated in patients who have not achieved continence using
behavioral and pharmacologic therapy. Surgical options vary according to the underlying anatomy and
the physiologic problem. Most procedures involve lifting and stabilizing the bladder or urethra to restore
the normal urethrovesical angle or to lengthen the urethra. Women with stress incontinence may
undergo an anterior vaginal repair, retropubic suspension, or needle suspension to reposition the
urethra. Procedures to compress the urethra and increase resistance to urine flow include sling
procedures and placement of periurethral bulking agents such as artificial collagen.
Periurethral bulking is a semipermanent procedure in which small amounts of artificial collagen
are placed within the walls of the urethra to enhance the closing pressure of the urethra. This procedure
takes only 10 to 20 minutes and may be performed under local anesthesia or moderate sedation.
A cystoscope is inserted into the urethra. An instrument is inserted through the cystoscope to deliver a
small amount of collagen into the urethral wall at locations selected by the urologist. The patient is
usually discharged home after voiding. There are no restrictions following the procedure, although
occasionally more than one collagen bulking session may be necessary if the initial procedure did not
halt stress incontinence. Collagen placement anywhere in the body is considered semipermanent
because its durability averages between 12 and 24 months, until the body absorbs the material.
Periurethral bulking with collagen offers an alternative to surgery, as in a frail, elderly person.
It is also an option for people who are seeking help with stress incontinence who prefer to avoid
surgery and who do not have access to behavioral therapies. An artificial urinary sphincter can be used
to close the urethra and promote continence. Two types of artificial sphincters are a periurethral cuff
and a cuff inflation pump. Men with overflow and stress incontinence may undergo a transurethral
resection to relieve symptoms of prostatic enlargement. An artificial sphincter can be used after prostatic
surgery for sphincter impotence. After surgery, periurethral bulking agents can be injected into the
periurethral area to increase compression of the urethra.
Surgical Procedures:
Implanting a suburethral sling
Implanting an artificial sphincter device
Cryoplasty
Reconstructing and lifting the bladder when it has fallen
Closing the bladder neck
Pharmacologic Therapy