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DEMENCIAS VASCULARES
Este artculo trata sobre el estado del arte en las demencias vasculares
con nfasis especial en los estudios que involucran las nuevas tcnicas
de evaluacin imagenolgica.
Palabras Clave: Demencia; Demencia multi-infarto; Demencia vascular
The Vascular Dementias are one of the most serious problems in the
medical studies. They are considered as the second cause of dementia
in the occidental word and they seem to be worst than the Alzaheimers
disease. It has not really explored because of the origin of the disease.
* Hospital San Isidro Universidad del Valle, Colombia. Research Fellow Neuropsiquiatra, Universidad
de Illinois, Chicago
** Divisin de Neuropsiquiatra. Departamento de Psiquiatra Universidad de Illinois, Chicago
Tabla 1
Tabla 2
SENSIBILIDAD Y ESPECIFICIDAD DE
LOS DIFERENTES CRITERIOS CLINICOS VS AUTOPSIA
Criterios
Chu, 1998 31% 92% 52% 83% 50% 89% 17% 97%
Tabla 3
Mltiples, unilaterales
SPECT Hipoperfusin frontal anterior, ganglios
basales
Cortical-subcortical izquierdo
Infartos grandes
generalizada
TAC atrofia
frontal, capsula interna
leucoaraiosis
tlamos
Corticales-subcorticales
Infartos de tamao variable
RMN especialmente izquierdos
HISB
periventricular
uso del cido acetil saliclico, entre En cuanto al uso de hidergina como
10000 pacientes con historia previa tratamiento en pacientes con DV, el
de infarto o de ataque isqumico tran- tamao de la muestra en los estudios
sitorio, se evitaron, 40 eventos vascu- impide sacar conclusiones definiti-
lares/1000 pacientes tratados; ade- vas. En algunos de ellos se ha repor-
ms hubo una disminucin significa- tado mejora significativa en pacien-
tiva en las muertes asociadas con tes recibiendo el frmaco, compara-
infarto. La dosis usada con mayor dos con aquellos tratados con place-
frecuencia fue la de 325mg/da. bo (Schneider, 1994).
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