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MARCH, 2017
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CHAPTER I
INTRODUCTION
Premature rupture of the membranes (PROM) is when the membranes rupture before the onset of
labour. In 80% of patients labour ensues within 24 hours. Once the membranes are ruptured the
barrier to ascending infection is gone and if labour does not follow within 24-48 hours, induction
of labour to prevent chorioamnionitis in the mother and systemic neonatal infection is usual.
PPROM is a major cause of perinatal mortality and morbidity. It is a associated with 20% to 30%
of all preterm births and prognosis is related primarily to the gestasional age at presentation and
delivery. A timely and accurate diagnosis of PROM is critical to optimize pregnancy outcome. A
better understanding of the diagnosis and managemet of PPROM will allow obstetric care
providers to optimize perinatal outcome and minimize neonatal morbidity.
When the buttocks of the fetus enter the pelvis before the head, the presentation is breech.
Breech presentation is more common remote from term because the bulk of each fetal pole is
more similar. Most often, however, as term approaches, the fetus turns spontaneously to a
cephalic presentation because the increasing bulk of the buttocks seeks the more spacious
fundus. Breech presentation persists in 3 to 4 percent of singleton deliveries at term.
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CHAPTER II
CASE PRESNTATION
I. IDENTITY
A. Patients identity
Name : Mrs. Y
Nationality : Indonesian
Ethnicity : Sundanese
Occupation : Housewife
Religion : Moslem
Name : Mr. R
Nationality : Indonesian
Ethnicity : Sundanese
Occupation : Worker
Religion : Islam
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II. ANAMNESIS
Chief Complaint
Patient admitted that she felt there were gush of fluid from her vagina since 14 hours before
admission.
History of Present
Patient came to hospital 28 March 2017 because she felt there were gush of fluid from her vagina
since 14 hours before admission. The watery discharge from her vagina was clear and bloody
show (-). Patient admitted that she started to feel some contraction since 3 hours before
admission, Patient also said that there were leaking of fluid everytime she felt the fetal
movement.
Family History
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Habitual History
Menstruation History
Contraception History
Marital History
Gestational History
Antenatal Care
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III. PHYSICAL EXAMINATION
Temperature : 36.0 C
Height : 152 cm
General Examination
Eye : palpebral edema -/- , anemic conjungtiva -/- , anicteric sclera -/-
Thorax
Cor : auscultation : regular 1st and 2nd heart sound, gallop (-), murmur (-)
Pulmo
Abdomen
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Palpation : supple in all abdomen region , tenderness (-)
Aucultation : bowel sound (+), 5-6x / minute
Extremitas : warm, edema -/-, CRT < 2s, physiological reflex ++/++/++/++,
pathological reflex -/-/-/-
Obstetric Examination
Fundus height : 28 cm
His : 2x10/30
Leopold
Internal Examination
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Conclusion : suspicious non stress test
V. ADMITION DIAGNOSIS
G1P0A0, 24 years old, 32-33 weeks of gestation, first stage of labor (latent phase) with premature
rupture of membrane. Single, intrauterine living fetus with breech presentation.
Conservative management
VII. FOLLOW UP
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March 28, 2017 ( 15.00 )
Vital sign :
Pulse : 82 x /minutes
Temperature : 36 C
Fundal height : 28 cm
Leopold
Internal Examination
Vulva : not found any abnormality
Vagina : not found any abnormality
Portio : consistency thick and soft
Dilatation : 2 cm Hodge-I
Fetal membrane : amniotic is positive but there are leakage of fluid but there are
leakage of fluid, breech presentation
His : 2x/10/20
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A : G1P0A0, 24 years old, 32-33 weeks of gestation, first stage of labor (latent phase) with
premature rupture of membrane. Single, intrauterine living fetus with breech
presentation.
Conservative management
S : patient felt the contraction of her uterus and the fetal movement
Vital sign :
Temperature : 36 C
Fundal height : 28 cm
Leopold
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Leopold III : palpable round, hard not bouncy, bottom
Leopold IV : divergen
Internal Examination
Vulva : not found any abnormality
Vagina : not found any abnormality
Portio : consistency thick and soft
Dilatation : 2 cm Hodge- II
Fetal membrane : amniotic is positive but there are leakage of fluid but there are
leakage of fluid, breech presentation
A : G1P0A0, 24 years old, 32-33 weeks of gestation, first stage of labor (latent phase) with
premature rupture of membrane. Single, intrauterine living fetus with breech presentation.
S : patient felt the contraction of her uterus and the fetal movement
Vital sign :
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Temperature : 36 C
Fundal height : 28 cm
Leopold
Internal Examination
Vulva : not found any abnormality
Vagina : not found any abnormality
Portio : consistency thin and soft
Dilatation : 9 cm Hodge II
Fetal membrane : amniotic is positive but there are leakage of fluid but there are
leakage of fluid, breech presentation
His : 4 times in 10 minutes, duration of contraction is 60 seconds
A : G1P0A0, 24 years old, 32-33 weeks gestation, first stage active phase with premature
rupture of membrane. Single, intrauterine living fetus with breech presentation.
Borned female baby with birth weight 2290 grams, height 44 cm, Apgar score 6/8 . placenta
borned spontaneously and amnionic is complete. There is no laceration of perineum and the
contraction of uterus is good.
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S : patient felt abdominal pain
Vital sign :
Temperature : 36 C
A : Mrs. Y,24 years old , P1A0, partus prematurus pervaginam with spontaneous brach
indication breech
Vital sign :
Temperature : 36 C
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Post partum bleeding : rubra
A : Mrs. Y,24 years old , P1A0, partus prematurus pervaginam with spontaneous brach
indication breech
Vital sign :
Temperature : 36.5 C
A : Mrs. Y,24 years old , P1A0, partus prematurus pervaginam with spontaneous brach
indication breech
Mrs.Y 24 years old P1A0, partus prematurus pervaginam with premature rupture of membrane
with spontaneous brach indication breech presentation.
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CHAPTER III
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- amniotic is positive but (ROM) is suspected examination and
there are leakage of with history of a gush or leopold we found the
fluid, breech leaking of fluid from the breech presentation
presentation vagina. Diagnosis can
be cofrimed by the pool,
nitrazine and fern test
Therapy Earlier the therapy is Study found that in we found that the
conservative management preterm premature gestational age are 32-
because of 32- 33 weeks of rupture of membrane 33 weeks, so it best to
gestational age. that happened in > 28 evaluate the option to
The palnning of therapy is weeks of gestation, it is terminate or doing the
termination of pregnancy best to discussed the expectative
option of therapy to the management and it will
patient family, be best if there are
especially about the coallaboration with
fetal and maternal risk, neonantalogist
whether the patient want
to choose the
termination or
expectative
management
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Problems :
Answers :
Amnionic epithelium is functioned as a major site of transfer between amnionic fluid and
amnion. This epithelium is metabolically active and its cells synthesize tissue inhibithor of
MMP-1, prostaglandin E2 (PGE2) and fetal fibronectin (fFN). In term pregnancies, amionic
expression of prostaglandin endoperoxide H synthase correlates with elevated fFN promote
synthesis of MMPs that break down the strength-bearing collangens and increases prostaglandin
synthesis to prompt uterine contractions and cervical ripening. This pathway is upregulated in
premature rupture membrane induced by infection
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amnionic fluid from women with ruptured membranes. Elevated MMP levels found at a time
when protease inhibitor expression decreases supports further that their expression alters
amniotic tensile strength. Increased MMPs allow collagen breakdown in fetal membranes
resulting in premature rupture
2. The diagnosis of this patient are : G1P0A0, 24 years old, 32-33 weeks of gestation, first stage of
labor (latent phase) with premature rupture of membrane. Single, intrauterine living fetus with
breech presentation.
Discussion :
Using a sterile speculum, rupture membrane are diagnosed if amnionic pools in the
posterior fornix or clear fluid flows from the cervical canal. This can be augmented by
asking the patient to cough or bear down, potentially allowing one to observe fluid
escaping from the cervix
If the diagnosis remain uncertain, we can use pH of vaginal fluid. Vaginal secretions are
normally acidic (4.5 to 5.5), whereas amniotic fluid is alkaline (7.0-7.5). Thus, when the
fluid is placed on nitrazine paper, the paper should immediately turn blue. A pH above
6.5 is consistent with ruptured membranes. Flase positive test results may occur with
coexistent blood, semen or bacterial vaginosis, whereas flase negative test may result
with scant fluid.
The estrogens in the amnionic fluid cause crystallization of the salts in the amnionic fluid
when it dries. Under low microscopic power, the crystals resemble the blades of a fern,
giving the test its name
For the diagnosis of premature contraction in this case, it is best to evaluate the characteristic
of contraction in this patient. In early pregnancy, the uterus undergoes irregular contractions that
are normally painless. During the three trimester, there are contractions that appear
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unpredictably, irregular and usually nonrythmic, these contractions called Barxton Hicks
contractions or usually known as false labor.
Conclusion : G1P0A0, 24 years old, 32-33 weeks of gestation, first stage of labor (latent phase)
with premature rupture of membrane. Single, intrauterine living fetus with breech presentation.
3. The earlier management of this patient is the conservative management because of there is the
uncertainty in the gestational age. But, after the fundal height examination and HPHT estimation
was done, the gestational age of this patient is 32-33 weeks. After the gestational age is certain,
there is a change in the planning of therapy. The planning of therapy in patient is to do the
termination of pregnancy with consent from patient and patients family.
Discussions :
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contraindication
Before 24 weeks ( the combinations of birth Patient conselling
weight, gestational age and sex provides the Expectant managemt or inductions of labor
best etimates chances of survival and should be Grup B streptoccal prophylaxis is
considered in individual cases recommended
Corticocosteroids are not recommended
consensus, but non experts recommended
Antimicrobials- there are incomplete data on
use in prolonging latency
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Once the membrane rupture, delivery is recommended when the risk of ascending infection to
maternal outweighs the risk of prematurity
Conculsion : the final management of this case is to the termination of pregnancy or induction of
labor before viability is considered because the risk of ascending infection to maternal outweight
the risk of prematurity
4. PPROM has been known as the main cause of preterm delivery and associated with increased
rates of neonatal and maternal morbidity and mortality. Although it has different cause, collagen
metabolism is considered as the main factor in premature rupture of membranes. Vitamin C
usage during pregnancy can modulated the collagen metabolism and cause the strength of
aminochorion membranes. Vitamin C is an antioxidant that blocks the damaging effects of
oxidative stress in vitro. Therefore, vitamin C can prevent premature rupture of membranes
through its role as an antioxidant or in collagen synthesis and maintenance. Vitamin C
supplement is recommended to be administered for pregnant women with the history of PPROM
during pregnancy to prevent PPROM.
5. The fetal membranes serve as a barrier to ascending infection. Once the membrane rupture,
both the mother and fetus are at risk of infection and of other complications.
Neonatal complications :
Maternal complications :
6. Breech presentation is more common remote from term. Most often, however, before the onset
of labor the fetus turns spontaneously to a cephalic presentation, so that breech presentation
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persists in only about 3 to 4 percent of singleton deliveries. Specifically, the annual rate of
breech presentation at delivery in nearly 150,000 infants delivered at Parkland Hospital in the
10-year period ending in 2002 was 3.6 percent.
As term approaches, the uterine cavity usually accommodates the fetus in a longitudinal lie with
the vertex presenting. Factors other than gestational age that appear to predispose to breech
presentation include hydramnios, uterine relaxation associated with great parity, multiple fetuses,
oligohydramnios, hydrocephaly, anencephaly, previous breech delivery, uterine anomalies, and
pelvic tumors. Fianu and Vaclavinkova (1978) provided sonographic evidence of a much higher
prevalence of placental implantation in the cornual-fundal region for breech presentation (73
percent) than for vertex presentations (5 percent). The frequency of breech presentation also is
increased with placenta previa, but only a small minority of breech presentations are
associated with a previa. No strong correlation has been shown between breech presentation and
a contracted pelvis.
7. The varying relations between the lower extremities and buttocks of breech presentations
form the categories of frank, complete, and incomplete breech presentations. With a frank breech
presentation, the lower extremities are flexed at the hips and extended at the knees, and thus the
feet lie in close proximity to the head (Fig. 28-2). A complete breech presentation differs in that
one or both knees are flexed (Fig. 28-3). With incomplete breech presentation, one or both hips
are not flexed and one or both feet or knees lie below the breech, such that a foot or knee is
lowermost in the birth canal (Fig. 28-4). Footling breech is an incomplete breech with one or
both feet below the breech.
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8. Understanding the clinical settings that predispose to breech presentations can aid early
recognition. Other than early gestational age, risk factors include abnormal amnionic fluid
volume, multifetal gestation, hydrocephaly, anencephaly, uterine anomalies, plasenta previa,
fundal placental implantation, pelvic tumors, high parity with uterine relaxtion, and prior breech
delivery.
9. A score of 6 clinical variables were made at the time of admission to hospital for predicting
the success of vaginal breech deliveries
Parameter Value
0 1 2
Primi Multi -
Breech presentation No One time Twice
Estimated fetal weight >3650 g 3649-3176 g < 3176 g
Gestation >39 weeks 38 weeks < 37 weeks
Station <-3 -2 -1 atau >
cervical dilation 2 cm 3 cm 4 cm
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