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International Journal of Applied Ayurved Research ISSN: 2347- 6362

MEDHYA (COGNITIVE ENHANCERS) HERBAL DRUGS OF


BHAVPRAKASH NIGHANTU: A LITERARY REVIEW
1 2
Kadam Rupa S Koul Anu
1
Asso. Professor, Dravyaguna Dept, YMT, Ayurvedic Medical College & Research
Centre,Kharghar, Navi Mumbai.
2
PG Scholar, Dravyaguna Dept, YMT, Ayurvedic Medical College & Research
Centre,Kharghar, Navi Mumbai.
ABSTRACT
Cognitive impairment can have devastating effects on a persons emotional and physical
well-being. The cognitive enhancers can be used to attenuate the impairment of cognitive
functions .In traditional practices of medicines, numerous plants have been used to treat
cognitive disorders. Ayurveda plays vital role in Cognitive disorders and explained them
under mansaroga. Many treatment modalities have been explained in Brihattrayi (Charka
Samhita, Susruta Samhita and Ashtang Hridyum) and Laghutrayi (Bhavprakash, Madhav
Nidan and Sharangdhara Samhita). In Bhavprakash Nighantu, a part of Bhavprakash
Samhita, Bhavmishra mentions certain drugs having Medhya property which can be
correlated with cognitive enhancement. These drugs can be used specifically to improve
memory and intellect. The present study was designed to screen the drugs from Bhavprakash
Nighantu with Medhya, medhavardhak, matiprada, medhakrit, buddhida, medhaprada,
medhakara, medhahito, Medhyagnivardhini, buddhismrutiprada, smrutibuddhida and
Smrutikara properties. Out of 426 drugs 23 drugs were described as cognitive enhancers
throughout the text. These screened drugs will be a handy reference for the treatment of
cognitive disorders.
Keywords: Cognition, Medha, Bhavprakash Nighantu.
INTRODUCTION: Cognition refers to a and diabetes. However, some causes of
range of high-level brain functions, cognitive impairment are related to health
including the ability to learn and remember issues that may be treatable, like
information to organize, to plan, to solve, medication side effects, vitamin B12
to focus, to maintain and shift attention as deficiency, and depression. Individuals
necessary; to understand and use language; may reduce the risk of cognitive
to accurately perceive the environment; impairment by keeping physically active
1
and perform calculations. Cognitive and maintaining healthy cholesterol and
disorders are a category of mental health blood sugar levels. 3
disorders that primarily affect learning, Available allopathic nootropic drugs may
memory, perception, and problem solving only delay or slow down disease
2
include amnesia, dementia, and delirium. progression. Also the side effects that they
While age is the primary risk factor for cause, make them unfit for regular
cognitive impairment, other risk factors consumption. This drives us to reach and
include family history, brain injury, develop alternative methods for cognitive
exposure to pesticides or toxins, physical enhancement. In Ayurveda, every complete
inactivity, and chronic conditions such as human being is considered as combination
Parkinsons disease, heart disease , stroke of both mind and body. The perfect
[Kadam Rupa S et al: Medhya (Cognitive Enhancers) Herbal Drugs of Bhavprakash Nighantu: A Literary Review]

combination of body, mind and soul is faculty of Buddhi (Knowledge)


6
considered as complete health in .Chakrapani opines that Medha is equated
Ayurveda. Ayurveda, being a stream of to Dhee, which means it is a type of Dhee
treatment, can no way ignore the having the power of retention of
importance of cognitive impairment. knowledge7
Ayurveda has already described several It is clear from Shabdakalpadruma that,
medicinal plants under the concept of medha is equivalent to Buddhi and Pragya,
Medhya dravya which refers to the agents because Pragya and Medha are the two
acting on higher brain function by synonyms of Buddhi among other names
interacting on ability or power of like Mati, Chit, Dharana etc8.
acquisition (intelligence), ability or power About Bhavprakash Nighantu9: In the
of retention and ability or power of recall field of Ayurveda, Nighantus play an
or memory by amelioration of Medha of important role. Literally, Nighantu means
the individuals. Most of the Ayurvedic the compilation of words with their root
Medhya dravyas have shown their efficacy meanings and synonyms. Ayurvedic
by acting on different receptors, thought to Nighantu put a foot ahead in including the
play a role in the prevention of cognitive properties, both morphological and
decline. pharmacological along with therapeutic
The herbs that are considered indications. Here in the text, the very
Medhya are said to be working with the purpose is fulfilled extra ordinarily with
higher brain function, or mind- the exhaustive efforts of Bhavmishra and
rejuvenating herbs. They engender and that is why Bhavprakash Nighantu is
summon intelligence, memory, mental considered the best among all the
perception, bring nervine and nervous Nighantus. Bhavprakash Nighantu is a
system restorative action4. The word comprehensive work in an elegant style
medha is derived from the Sanskrit root and simple language. He had touched
medhri sangame which means to meet practically all the aspects & added new
or to come together or harmonize. Medha information based on the knowledge and
means, the knowledge Buddhi, Dhee traditions of that age as well as his own
which has power of retaining knowledge experiences as a scholar, physician, The
for very long period to have proper clarity present in his style of presentation,
correlation and understanding about the excellence of arrangements, systematic
knowledge of the existing objects. Without classification of drugs has illuminated and
medha, knowledge cannot be understood. resolved many obscure and disputed
Acharyas opines that means ability of passages of the ancient writers and his
discrimination of objects, further without important compilation marks the last
medha, knowledge cannot be understood revival of old Ayurvedic literature and is
and it is defined as that which groups or considered as a thesaurus of all the useful
retains knowledge5. According to information reaped from the vast field of
Dalhana, it is a power, which retains the millenniums old Ayurvedic literature. For
knowledge of text and also said that medha each drug he gave synonyms,
is very deep knowledge gained for the long properties/qualities, and therapeutic
period. According to Arunadatta, Medha is applications .At many places he tried to
equated to Buddhi, which means it is a clarify the identification of a particular
242 www.ijaar.in IJAAR VOLUME III ISSUE II MAY-JUNE 2017
[Kadam Rupa S et al: Medhya (Cognitive Enhancers) Herbal Drugs of Bhavprakash Nighantu: A Literary Review]

plants species. There is some To analyze their property mentioned in


consciousness observed in the plant the Bhavaprakash Nighantu.
names, which is corrected by later MATERIALS AND METHODS:
commentators depending upon this Bhavprakash Nighantu was explored for
Nighantu part. This Nighantu is considered the herbal drugs having Medhya property
as the latest among classical works in the i.e. cognitive enhancer property. The data
field of Dravyaguna Nighantu and is thus obtained was tabulated to analyze the
commonly followed by physicians and properties of those drugs.
students of Dravyaguna. Out of 426 herbal METHOD: In Bhavprakash Nighantu the
drugs, 23 drugs have been mentioned Medhya property was described by various
having Medhya properties. Hence this synonyms like Medhya. medhavardhak,
study planned to review and explore the matiprada, medhakrit, buddhida,
potential drugs having Medhya i.e. medhaprada, medhakara, medhahito,
memory enhancing property. Medhyagnivardhini, buddhismrutiprada,
AIM AND OBJECTIVES: smrutibuddhida, Smrutikara. All the drugs
To collect the information regarding mentioned having these properties were
the herbal drugs mentioned as Medhya sorted and tabulated for their identity and
in Bhavprakash Nighantu. properties. The tabulated data was
analyzed for Raspanchaka systematically.
Table no 1: List of Medhya herbal drugs in Bhavprakash Nighantu
HERBAL BOTANICAL
S.No. FAMILY REFERENCES
DRUG NAME
Terminalia chebula
1 Haritaki Combretaceae Haritakyadi Varga
Retz.
2 Pippali Piper longum Linn Piperaceae Haritakyadi Varga
Cuminum cyminum
3 Jirak Umbelliferae Haritakyadi Varga
Linn
4 Jirak(krishna) Carum carvi Linn Umbelliferae Haritakyadi Varga
5 Kalonji Nigella sativa Linn Ranunculaceae Haritakyadi Varga
Celastrus
6 Jyotishmati Celastraceae Haritakyadi Varga
paniculatus Willd.
7 Rason Allium sativum Linn Liliaceae Haritakyadi Varga
Semicarpus
8 Bhallatak Anacardiaceae Haritakyadi Varga
anacardium Linn f.
Nardostachys
9 Jatamansi Valerianaceae Karpuradi Varga
jatamansi DC.
Vitex agnus- castus
10 Renuka Verbenaceae Karpuradi Varga
Linn
Clerodendrum
11 Sthouneyak Verbenaceae Karpuradi Varga
infortunatum Linn
Gmelina arborea
12 Gambhari Verbenaceae Guduchyadi Varga
Linn
13 Aparajita Clitorea ternatea Fabaceae Guduchyadi Varga

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[Kadam Rupa S et al: Medhya (Cognitive Enhancers) Herbal Drugs of Bhavprakash Nighantu: A Literary Review]

Linn
Asparagus
14 Shatavari Liliaceae Guduchyadi Varga
racemosus Wild.
Croton
15 Nagdanti Euphorbiaceae Guduchyadi Varga
oblongifollius Roxb.
Argyreia speciosa
16 Vriddhdaruk Convolvulaceae Guduchyadi Varga
sweet.
Sphaeranthus
17 Mundi Compositae Guduchyadi Varga
indicus Linn
Evolvulus
18 Shankhapushpi Convolvulaceae Guduchyadi Varga
alsinoides Linn
Bacopa monnieri
19 Brahmi Scrophulariaceae Guduchyadi Varga
Linn
20 Kaidarshali Oryza sativa Linn Gramineae Dhanya Varga
Hordeum vulgare
21 Yava Gramineae Dhanya Varga
Linn.
Sesamum indicum
Til Pedaliaceae Dhanya Varga
22 Linn
Chanchuki Corchorus Tiliaceae
23 Shak Varga
fascicularis Lam.
Table no 2: List of Medhya herbal drugs by Bhavprakash Nighantu according to
Raspanchaka
S. HERBAL PRABHA
RASA GUNA VIRYA VIPAK
No DRUG V
Kashaya,Madhura Ruksha,Lag Madhur Tridoshgh
1 Haritaki Ushna
,Amla,Katu,Tikta hu a na
Snigdha,Lag Anushnash Madhur Not
2 Pippali Katu
hu eet a mentioned
Not
Ruksha,Lag Not
3 Jirak Katu Ushna mention
hu mentioned
ed
Not
Jirak(krishna Ruksha,Lag Not
4 Katu Ushna mention
) hu mentioned
ed
Not
Ruksha,Lag Not
5 Kalonji Katu Ushna mention
hu mentioned
ed
Not
Not
6 Jyotishmati Katu,Tikta Sara Ushna mention
mentioned
ed
Katu,Tikta, Snigdha,Gur Not
7 Rason Ushna Katu
Kashaya, u, mentioned

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[Kadam Rupa S et al: Medhya (Cognitive Enhancers) Herbal Drugs of Bhavprakash Nighantu: A Literary Review]

Lavan,madhura Tikshna
Snigdha,Lag Not
Not
8 Bhallatak Kashaya.Madhura hu, Ushna mention
mentioned
Tikshna ed
Not
Not Not
9 Jatamansi Tikta,Kashaya Sheet mention
mentioned mentioned
ed
Not
10 Renuka Tikta,Katu Laghu Ushna Katu
mentioned
Not
Katu,Madhura,Tik Not Not
11 Sthouneyak Snigdha mention
ta mentioned mentioned
ed
Not
Madhura,Kashya, Not
12 Gambhari Guru Ushna mention
Tikta mentioned
ed
Not Not
13 Aparajita Katu,Tikta,Kashya Sheet Katu
mentioned mentioned
Not
Snigdha, Not
14 Shatavari Tikta,Madhura Sheet mention
Guru mentioned
ed
Not
Ruksha,Lag Not Not
15 Nagdanti Katu,Tikta mention
hu mentioned mentioned
ed
Not
Kashaya.Katu,Tikt Not
16 Vriddhdaruk Sara Ushna mention
a mentioned
ed
Mundi
Not
17 Madhura Laghu Ushna Katu
mentioned

Not
Shankhapush Not
18 Kashaya Sara Ushna mention
pi mentioned
ed
Tikta,Kashaya, Madhur Not
19 Brahmi Sara, Laghu Sheet
Madhura a mentioned
Not
Not
20 Kaidarshali Kashaya Guru Sheet mention
mentioned
ed
Guru,Ruksh
a, Not
21 Yava Kashaya,Madhura Sheet Katu
Picchil, mentioned
Abhishyandi
Katu,Tikta,madhur Snigdha,Gur Not
Til Ushna Katu
22 a, u mentioned

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[Kadam Rupa S et al: Medhya (Cognitive Enhancers) Herbal Drugs of Bhavprakash Nighantu: A Literary Review]

Kashaya
Not
Chanchuki Not
Madhura Picchil,Sara Sheet mention
23 mentioned
ed
RESULTS: The above tabulated herbal drugs were analyzed for Rasapanchaka (Rasa, Guna,
Virya and Vipaak) and the following are noticed:
Table no.3 Medhya Herbal drugs according to Rasa
S.NO RASA NO.OF HERBAL DRUGS PERCENTAGE
1 Madhuraa 11 48%
2 Amla 01 04%
3 Lavana 01 04%
4 Katu 12 52%
5 Tikta 13 56%
6 Kashaya 12 52%
It is observed that, in the above table, Tikta rasa dravya are maximum in number (13)
followed by Katu rasa and Kashaya rasa (12), Madhuraa rasa (11) Amla rasa and Lavana
rasa (01). This clearly indicates that the herbal drugs with Tikta, Katu ,Kashaya and
Madhuraa rasa play significant role as Medhya.
Table No.3 Medhya Herbal drugs according to Viryas
S.NO VIRYA NO. OF HERBAL DRUGS PERCENTAGE
1 Ushna 13 56%
2 Sheeta 07 30%
3 Anushnasheeta 01 04%
Most of the herbal drugs mentioned are Ushnavirya in nature (13) followed by Sheetavirya
(07) and Anushnasheetvirya (01).
Table no.4 Medhya Herbal drugs according to Vipaak
S.NO VIPAKA NO.OF HERBAL DRUGS PERCENTAGE
1 Madhura vipaka 03 13%
2 Katu vipaka 06 26%
3 Amla vipaka 0 0%
Madhurarvipak (03) Katuvipaka (06) and Amlavipaka (0) are mentioned to have the Medhya
property.
Table no.5 Medhya Herbal drugs according to Guna
S.NO GUNA NO.OF HERBAL DRUGS PERCENTAGE
1 Ruska 06 26%
2 Laghu 10 43%
3 Tikshna 02 9%
4 Sara 03 13%
5 Snigdha 06 26%
6 Guru 05 22%
7 Picchil 02 9%
8 Abhishyandi 01 4%

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[Kadam Rupa S et al: Medhya (Cognitive Enhancers) Herbal Drugs of Bhavprakash Nighantu: A Literary Review]

Laghu (10), Ruksa and Snigdha (06), Guru thereby increases Dhatvagnis.Increased
(05), Sara (03), Tikshna and Picchil (02), Dhatvagni, in turn increases
Abhishyandi (01) are mentioned to be Majjadhavtagni i.e. nourishes
mostly acting as Medhya. Majjadhatu.Madura rasa because of its
DISCUSSION: Bhavamishra has given suitability to the body promotes
idiosyncrasy consideration to the Majjadhidhatu.Kashaya Rasa pacifying
impairment of cognition and used various kapha, rakta and pitta giving cooling
drugs for this Condition. Present study effect and stimulates the retention power
deals with extensive variety of herbal (dhriti). Katu rasa stimulates the
drugs from Bhavprakash Nighantu. sadhakpitta which in turns gives
Bhavamishra directly mentions the karma or nourishment to Buddhi. Thus, it stimulates
action of these drugs as Medhya (cognitive intellect due to Tikta, Kashaya, Katu and
enhancer) .Herbal Drugs from whole Madhura Rasa. This clearly indicates that
Bhavprakash Nighantu were screened for the herbal drugs with Tikta, , Kashaya,
the action Medhya (Cognitive enhancer). Katu and Madhura rasa play significant
Obtained data were presented as per role as Medhya. Ushnavirya 13(56%)
rasapanchak and along with different drugs are maximum in number followed
Vargas (chapter wise classification) with by Sheetavirya 07(30%) and
corresponding reference. Out of 426 drugs Anushnasheetvirya 01(4%) in nature.
from Bhavprakash Nighantu 8(1.88%) Usnavirya dravya acts on pachaka,
belong to Haritakyadi Varga, sadhaka, alochaka pitta, reduces avarana
3(0.70 %) of drugs from Karpuradi varga, 8 of raja and tamas and Strotoshodan
(1.88%) belong to Guduchyadi varga. action at the level of Manovahastrotas
Subsequent to herbal origin Dhanyadi and Rasavahastrotas which enhance power
Varga 3 (0.70%) and Shaka Varga 1 of Smarana(Acquiring new information)
(0.23%) has been stated as cognitive and Grahana (data interpretation) i.e.
enhancer. stimulates dhi, smriti while Sheetavirya
It is observed that, of the herbal drugs herbs acts by increasing nourishment to the
mentioned as Medhya rasa dravya are neuronal matter of brain via tarpaka and
maximum in number Tikta rasa 13 (56%) avlambkha kapha which improves dharana
followed by Katu rasa and Kashaya rasa (retention power). Anushnasheetvirya
12 (52%), Madhura rasa 11(48%) ,Amla dravya gives stimulation to dhi, smriti and
rasa and Lavana rasa 01(4%). Tikta rasa retention power.
causes stimulation to jatharagni and
GRAPH 1: MEDHYA ACCORDING TO RASA

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[Kadam Rupa S et al: Medhya (Cognitive Enhancers) Herbal Drugs of Bhavprakash Nighantu: A Literary Review]

12 13 12
15 11
10
48% 4% 4% 52% 56% 52%
5 1 1
0
Madura Amla Lavana Katu Tikta Kasaya

Series1 Series2

GRAPH 2: MEDHYA ACCORDING TO VIRYA

20 13 56%
30%
7 4%
0 1
Ushna
Sheeta
Anushnasheeta

NO. OF HERBAL DRUGS PERCENTAGE

GRAPH 3: MEDHYA ACCORDING TO VIPAAK

8
26%
6
4 13% 6
2 3
0%
0
0
Madhura vipaka Katu vipaka Amla vipaka

NO.OF HERBAL DRUGS PERCENTAGE

GRAPH 4: MEDHYA ACCORDING TO GUNA

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[Kadam Rupa S et al: Medhya (Cognitive Enhancers) Herbal Drugs of Bhavprakash Nighantu: A Literary Review]

10
10 6 6 5
5 26% 43% 2 3 22% 2
13% 26% 1
9% 9% 4%
0 Series1

Series1 Series2

CONCLUSION: Medha is combination 7) Chakrapanidatta, Charaka Samhita


of power of acquisition (Grahan), sutra sthana chapter 27 sloka 350.Jadavaji
retention (Dharan) and recollection Trikamji Acharya editor. Reprinted
(Smaran). Tikta, Madura, Kashaya Rasa edition. Varanasi: Chaukhamba Sanskrit
and Ushna, sheet virya drugs acts through sansthana; 2004. P.174
different mechanism and enhance 8) Raja Radha Kantadeva,
cognition. This research paper Shabdakalpadruma vol. 3. Shri
demonstrates that out of 426 drugs 23 Vardaprasad editor.3rd edition. Varanasi:
drugs of herbal were described as Chaukhamba series office; 1967. P. 434
cognitive enhancers throughout the text. 9) Bhavapraksh Nighantu, Dr.
These screened drugs will be a handy K.C.Chunekar, Dr. G.S.Pandey Revised
reference for the treatment of cognitive and enlarged edition 2010 Chaukhambha
disorders. This study may provide Bharati Academy, Varanasi.
parameters for selection of Medhya drug in Corresponding author: Dr Rupa S
different memory disorder. Kadam, Asso Professor, YMT, Ayurvedic
REFERENCES: Medical College & Research
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2) https://en.wikipedia.org/wiki/Cogniti Conflict of interest: None
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