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Cell Biology
Lecture #3
Cell wall vs. Cell membrane
All living cells have cell membranes (plasma
membrane).
Proteins =
a) Integral (intrinsic)
b) Peripheral (extrinsic)
The Fluid Mosaic Model
Membrane proteins
1- Integral proteins
They are inserted into the membrane so their hydrophobic
regions are surrounded by hydrocarbon portions of
phospholipids. They may be:
Unilateral, reaching only part way across the
membrane.
Transmembrane, with hydrophobic midsections
between hydrophilic ends exposed on both sides.
Peripheral proteins
They are not embedded but attached to
the membrane's surface.
Membrane Carbohydrates
They are usually branched oligosaccharides.
2-Enzymatic activity.
4- Cell-cell recognition.
Some glycoproteins serve as
identification tags that are
specifically recognized by other
cells.
Functions of membrane proteins
5- Intercellular joining.
Membrane proteins of adjacent cells may
hook together in various kinds of
junctions, such as gap junctions or tight
junctions
6- Attachment to the
cytoskeleton and extracellular
Matrix (ECM).