Name of Drug Classification Dose/Freq/Route Mechanism of Action Indication Side effect Nursing Implication

Proglin Anti-Diabetic 50mg/OD/PO Vildagliptin, a Adjunct to diet and Constipation, Peripheral Caution should be
member of the islet exercise to improve edema, Headache, Tremor, exercised in patients
enhancer class, is a glycemic control in dizziness, headache, with history of severe
potent and selective patients with type 2 Asthenia, Decreased blood kidney disease.
dipeptidyl-peptidase- diabetes mellitus ( glucose, Hyperhidrosis,
4(DPP-4) inhibitor T2DM) Urticaria, pancreatitis, It may cause dizziness or
that improves localized exfoliation or fatigue, do not drive a
glycemic control. blisters car or operate
The administration of machinery while taking
vildagliptin results in this medication.
rapid and complete
inhibition of DPP-4 Patient may develop
activity. In patients with increased risk of
with type 2 diabetes, foot ulcers and blistering
administration of of the skin; if it is so
vildagliptin led to consult with your
inhibition of DPP-4 doctor.
enzyme activity for a
24-hr period. Monitor liver function
Vildagliptin inhibition and blood sugar level
of DPP-4 results in regularly while taking
increased fasting and this medication.
postprandial
endogenous levels of Avoid excess dosage.
the incretin
hormones glucagon-
like peptide 1 (GLP-1)
and glucose
dependent
insulinotropic
polypeptide (GIP).