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Prescribing Information.
What Is ARIMIDEX (anastrozole)? Enroll today and receive:
ARIMIDEX 1 mg is a prescription hormonal Brand name ARIMIDEX
Just $1 a day
treatment that helps fight breast cancer by
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lowering the amount of estrogen in the body. Auto refills
ARIMIDEX, taken once-daily, is a selective, Refill reminders
non-steroidal aromatase inhibitor, which Quarterly newsletters
significantly lowers serum estradiol (estrogen) Pharmacist support
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concentrations, without interfering with the
formation of adrenal corticosteroids
Enrollment in ARIMIDEX Direct is easy. Simply
or aldosterone. complete the online form on Arimidex.com
and send your prescription to Eagle Pharmacy.
Take Control with ARIMIDEX Direct Once youve enrolled in the program and sent
your prescription to Eagle Pharmacy, you will
If you and your doctor determine ARIMIDEX is receive your order in 710 days.
right for youall you need is a valid prescription
for ARIMIDEX or generic anastrozoleincluding Visit Arimidex.com today for more information.
if you are on Medicaid or Medicare Part Dto
enroll in ARIMIDEX Direct.

With ARIMIDEX Direct, you

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will receive your ARIMIDEX
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Important Safety Information
About ARIMIDEX (anastrozole)
Prescription ARIMIDEX is only for postmenopausal women.
ARIMIDEX should not be taken if you are pregnant because it
may harm your unborn child. Do not take ARIMIDEX if you are
allergic to any of its ingredients
B
 ased on information from a study in patients with early
breast cancer, women with a history of blockages in heart
arteries (ischemic heart disease) who take ARIMIDEX may
have a slight increase in this type of heart disease compared
to similar patients who take tamoxifen
A
 RIMIDEX can cause bone softening/weakening
(osteoporosis) increasing the chance of fractures. In a clinical
study in early breast cancer, there were more fractures
(including fractures of the spine, hip, and wrist) with
ARIMIDEX (10%) than with tamoxifen (7%)
In a clinical study in early breast cancer, some patients taking
ARIMIDEX had an increase in cholesterol. Skin reactions,
allergic reactions, and changes in blood tests of liver function
have also been reported
In the early breast cancer clinical trial, the most common
side effects seen with ARIMIDEX include hot flashes, joint
symptoms (including arthritis and arthralgia), weakness,
mood changes, pain, back pain, sore throat, nausea and
vomiting, rash, depression, high blood pressure, osteoporosis,
fractures, swelling of arms/legs, insomnia, and headache
In advanced breast cancer trials, the most common side
effects seen with ARIMIDEX versus tamoxifen include hot
flashes, nausea, decreased energy and weakness, pain, back
Please read accompanying full Prescribing Information.
pain, headache, bone pain, increased cough, shortness of
breath, sore throat, and swelling of arms and legs. Joint pain/
stiffness has been reported in association with the use of
ARIMIDEX
A
 RIMIDEX should not be taken with tamoxifen or estrogen-
containing therapies
APPROVED USES FOR ARIMIDEX
ARIMIDEX is approved for adjuvant treatment (treatment
following surgery with or without radiation) of postmenopausal
women with hormone receptor-positive early breast cancer.
ARIMIDEX is approved for the initial treatment of
postmenopausal women with hormone receptor-positive or
hormone receptor-unknown locally advanced or metastatic
breast cancer and for the treatment of postmenopausal women
with advanced breast cancer that has progressed following
treatment with tamoxifen. Patients with hormone receptor-
negative disease and patients who did not previously respond
to tamoxifen therapy rarely responded to ARIMIDEX.
For more information, see your doctor.
Please read accompanying full Prescribing Information.
If you cant afford your medication, AstraZeneca may be able
to help. For more information, please visit www.AstraZeneca-
us.com
You are encouraged to report negative side effects of
prescription drugs to the FDA. Visit www.FDA.gov/medwatch or
call 1-800-FDA-1088.
ARIMIDEX is a registered trademark of the AstraZeneca group of
companies. 2015 AstraZeneca. All rights reserved. 3111404 6/15