Course Content

Phase A (Block 6 & 7)

Prof. Dr. Sarwar Alam

1. Radiobiology

Physics & chemistry of radiation absorption

Molecular mechanism of DNA & chromosome damage
Aspects of radiation induced cell killing
Immediate radiochemical effect
LET
Cell survival curve with mathematical aspect
Stochastic & Non-stochastic effect
Volumetric RT

2. Revision of Oncopharmacology

Associate Professor Dr. Md. Abdul Bari

Medical Physics:

Penumbra
Beam modifying devices (wedge, Bolus, Compensator)
PDD
Iso dose distribution
Tumor dose specification for external photon beam/ volume definition
Acquisition of patient data
Treatment simulation
Branchy therapy:
a) Interstitial
b) Intraluminal
c) Intravascular
Special Procedures & techniques in RT

Associate Professor Dr. Zillur Rahman Bhuiyan

Dose distribution and scatter analysis

Dosemetric calculation
Radiation detectors: TAR, BSF, TPR, TMR
QA/Qc
Acceptance test, commissioning
Radiation protection
Assistant Professor Dr. Sadia Sharmin

1. Radiobiology:

O2 effect
Cell Cycle & radiosensitivity
Iso response curve
Fractionation & 4R in RT
ARS
Radioprotectors
Radiosensitizer
Hyperthermia
Retreatment after RT
TDF
OER, Therapeutic ratio, RSE, BED, NSD, NTCP, TCP

2. Introduction of radiotherapy machines, LINAC & other equipment

3. Concept of new modalities in RT

 Course Content for
Phase-A, Block-7

Radiobiology:

1. Acute Radiation Syndrome

2. Radioprotector
3. Radiation Carcinogenesis
4. Hyperthermia
5. Radiosensitizer
6. OER, Therapeutic ratio, RBE, BED, NSD, NTCP, TCP.
7. Volumetric RT
8. TDF
9. Retreatment after RT

Once pharmacology:

1. Concern Vaccine
2. Chemo therapeutic regimens in clinical practice
3. Newer agents in chemotherapy

Radiophysics:

1. Tumor dose specification for external photon beam/volume definition

2. Acquisition of patient data
3. Treatment simulation
4. Dose Calculation for
LINPAC
Co 60
Irregular field
Asymmetric field
5. Concept of immobilization & reproducibility
6. Monitor unit/MU
7. DVH
8. Special Procedures & techniques in RT
9. Concept of new modalities in RT
10. Branchy therapy:
Interstitial
Intraluminal
Intravascular
 Course Content for
Phase- A, Block- 6

Radiobiology:

1. Cell cycle & Radiosensitivity

2. Biological effect of radiation
3. Aspects of radiation induced cell killing
4. Molecular mechanism of DNA & chromosome damage
5. Immediate radio-chemical effect
6. Stochastic & non-stochastic effect
7. Physics & chemistry of radiation absorption
8. How free radicals are produced in Radiotherapy
9. 4R/ 5R in RT
10. Fractionation, Importance
11. Cell survival curve with mathematical aspect
12. LET
13. Iso response curve
14. O2 effect

Oncopharmacology:

1. Common chemotherapeutic agents (Revisions)

2. Hormonal therapy
3. MTT & Immunotherapy
4. Biological response modifiers
5. Antiemetic
6. Misc. drugs

Radiophysics:

1. Shielding calculation
RT bunker design
Other aspects of establishment of RT center
2. Radiation detector, TAR, BSF, TPR, TMR
3. Dose distribution & scatter analysis
4. Iso dose distribution
5. LINAC & other equipments machine with practical demonstration
6. PDD
7. QA/Qc
8. Acceptance test of LINAC, Commissioning
9. Penumbra
10. Wedge, wedge field technique/ Beam modifying devices