DDS Laboratory Exam Preliminary Period

Rx

Propranolol ------------ 15mg

Lactose, q.s.ad ---------50mg/powder paper

Make: 5 powder papers

1) (2 points) What is the amount of lactose needed to make the above prescription?

2) (3 points) If 50mg tablet is the only preparation available in the market, how many tablets are
you going to need to prepare 10 paper tablets? Show your solution on the space provided.

3) (8 points) What are the different containers for powder papers? Describe them according to
their moisture resistance capacity.

4) (2 points) If Propranolol tablets are to be used to make the above prescription, what process
must be done to reduce the particle size of the tablets? Describe how it is done (e.g. what
equipment must be used and how to use the equipment).
Multiple choice

1. Method of dividing powders used in paper tablet and compounded capsule preparations:
a. Tablet splitting c. Crush-and-estimate
b. Block-and-divide d. Dissolve-and-divide

2. Granules formed in mixing citric acid monohydrate, tartaric acid and sodium bicarbonate
a. Hygroscopic granules c. Efflorescent granules
b. Effervescent granules d. Explosive granules

3. Use of lactose in preparations

a. Diluent c. BOTA
b. Filler d. NOTA

4. Which of the following excipients is the disintegrant in the tablet preparation?

a. Water c. Lactose
b. Alcohol d. Cornstarch

5. What is the use of stearic acid in tablets?

a. Colorant c. Glidant
b. Filler d. Flavorant

6. Which sieve results to smallest particle size?

a. Sieve # 80 c. Sieve # 60
b. Sieve # 10 d. Sieve # 20

7. Process of grinding powders on mortar and pestle to reduce particle size of powders
a. Comminution c. BOTA
b. Trituration d. Pounding

8. If only citric acid powder is available instead of citric acid monohydrate, what remedy can be
done for this?
a. Soak citric acid powder in water and use the solution in the preparation
b. Sprinkle with alcohol and use in the preparation
c. Sprinkle with water and use in the preparation
d. Soak citric acid powder in alcohol and use the solution in the preparation

9. What is release when water is added to the effervescent granules?

a. H2O c. H2O2
b. CO2 d. O2

10. Other name for Paracetamol?

a. Thymol c. Aspirin
b. Acetic acid d. Acetaminophen