Académique Documents
Professionnel Documents
Culture Documents
N Personal genomics
N Natural genetic variation in populations (humans and others)
N Structure and function of genes and chromosomes
N Genetic variation arises by mutation
N Genetic variation and evolution (selection for function, phylogeny, homologs, gene families)
N How genes affect phenotypes: pathways, regulatory interactions, heterozygosity, dominance effects (several classes)
N Genetic variation also arises by chromosome reassortment and homologous recombination
N Mitosis and meiosis: mechanisms and genetic consequences (several classes)
N Mating: mechanisms and genetic consequences
N Linkage and sex linkage
N Genetic analysis: investigating gene action using inheritance of simple (Mendelian) alleles and phenotypes in crosses and
pedigrees (several classes)
N Organelle genetics
N Epigenetic inheritance
N Genome structure, function and evolution; causes and consequences of chromosomal changes (several classes)
N Phenotypic effects of natural genetic differences, heritability
N Genome-wide association studies and related studies linking genes to phenotypes (several classes)
N Genetics of cancer; inheritance of alleles affecting risk
References
1. Griffiths AJF, Wessler SR, Carroll SB, Doebley J 4. Smith MK, Knight JK (2012) Using the Genetics a genetic literacy assessment instrument for
(2012) Introduction to genetic analysis. 10th Concept Assessment to document persistent undergraduates. Genetics 178: 1522.
edition. New York: W. H. Freeman and Co. conceptual difficulties in undergraduate genetics 7. The International HapMap Consortium (2010)
832 p. courses. Genetics 191: 2132. Integrating common and rare genetic variation
2. Hartwell LH, Hood L, Goldberg ML, Reynolds 5. Smith MK, Wood WB, Knight JK (2008) The in diverse human populations. Nature 467: 52
AE, Silver LM (2011) Genetics, from genes to Genetics Concept Assessment: a new concept 58.
genomes. 4th edition. New York: McGraw-Hill. inventory for gauging student understanding of 8. Clarke L, Zheng-Bradley X, Smith R, Kulesha E,
730 p. genetics. CBE Life Sci Educ 7: 422430. Xiao C, et al. (2012) The 1000 Genomes Project:
3. Darlington CD, Mather K (1949) The elements of 6. Bowling BV, Acra EE, Wang L, Myers MF, Dean data management and community access. Nat
genetics. Sydney: Allen and Unwin. 446 p. GE, et al. (2008) Development and evaluation of Methods 9: 459462.