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Objective. To estimate the US prevalence and psychological and health behavior correlates of low back pain and/or neck
pain. No current US national prevalence estimates of low back and neck pain exist and few studies have investigated the
associations between low back and neck pain, psychological factors, and health behaviors in a representative sample of
US community dwellers.
Methods. We analyzed data obtained from adults ages 18 years or older (n 29,828) who participated in the 2002
National Health Interview Survey, a cross-sectional, population-based survey of US adults.
Results. The 3-month US prevalence of back and/or neck pain was 31% (low back pain: 34 million, neck pain: 9 million,
both back and neck pain: 19 million). Generally, adults with low back and/or neck pain reported more comorbid
conditions, exhibited more psychological distress (including serious mental illness), and engaged in more risky health
behaviors than adults without either condition.
Conclusion. Low back and neck pain are critical public health problems. Our study supports the idea of a multidimen-
sional approach to examining low back and neck problems and suggests the need for further research to address
potentially modiable psychological factors and health behaviors in these populations.
KEY WORDS. Back pain; Neck pain; Health behaviors; Psychological distress.
656
Back and Neck Pain, Mental Distress, and Behaviors 657
grouped together. From each group, 1 counties are se- domains: type of comorbidity (5 groups) and quantity (to-
lected (called the primary sampling unit [PSU]). Within tal number). Sociodemographic characteristics included
each PSU a sample of small land areas or groups of ad- age, sex, race/ethnicity, education level, marital status,
dresses are selected (called segments). From each segment and employment status.
a random sample of household addresses are obtained and
assigned to an interviewer in 1 quarterly samples (7). Assessment of psychological factors. The NHIS mea-
Each selected household is contacted via an advance letter sures nonspecic psychological distress over a 30-day re-
describing the survey. Trained interviewers from the US call period with the Kessler 6 (K6) scale (9 11). The K6
Census Bureau visit each selected household, obtain per- scale queries respondents in 6 domains: During the past
mission, and administer the NHIS in person. The inter- 30 days, how often did you feel: a) So sad that nothing
view consists of 3 core components: the Family Core, the could cheer you up? b) Nervous? c) Restless or dgety? d)
Sample Adult Core, and the Sample Child Core, in addi- Hopeless? e) That everything was an effort? and f) Worth-
tion to supplemental modules. less? Possible responses are none of the time, a little of
Our study used data obtained from the Sample Adult the time, some of the time, most of the time, and all of the
Core, which collects information from a randomly selected time, with points 0, 1, 2, 3, and 4 assigned to each category,
adult per family on health conditions, activity limitations, respectively. Item scores are summed for a total score of
health behaviors, and access to and use of health care 0 24 (12). According to scoring criteria established by
services. In 2002, 31,044 adults were interviewed, with a Kessler et al, persons with a score 13 are considered
response rate of 74.4%. Data were weighted to reect the likely to have serious mental illness (11,12). Clinically,
probability of selection, along with adjustments for nonre- serious mental illness is dened as any one 12-month
sponse and poststratication to produce national estimates Diagnostic and Statistical Manual of Mental Disorders,
(8). NHIS methods, including details on the weighting Fourth Edition disorder from the Structured Clinical Inter-
procedure, were described in detail elsewhere (6,8). view (other than a substance use disorder) and a clinically
rated Global Assessment of Functioning score 60 (11). A
Back and neck pain status. Back or neck pain was de- K6 score 13 equalizes false positives and false negatives,
ned as a yes response to the following 2 questions: The thus creating a total classication accuracy of 0.92 (11). A
following questions are about pain you may have experi- separate, dichotomous variable (all/most of the time ver-
enced in the past 3 months. Please refer to pain that lasted sus some/little/none of the time) was also created for each
a whole day or more. Do not report aches and pain that are K6 item. Additionally, we examined responses to the fol-
eeting or minor. During the past 3 months did you have lowing 4 yes/no questions about the prior 12 months that
low back pain? and During the past 3 months did you are asked independent of the K6 scale: Have you been
have neck pain? Persons who reported low back pain frequently depressed or anxious?; Have you regularly
without neck pain were considered to have low back pain
had insomnia or trouble sleeping?; Have you had exces-
only (LBPO); persons who reported neck pain without low
sive sleepiness during the day?; and Have you had re-
back pain were considered to have neck pain only (NPO);
curring pain?
persons reporting both low back and neck pain were con-
sidered to have both conditions (LBPNP). The comparison
Assessment of health behaviors. Current smokers were
group comprised persons with neither condition.
dened as persons who reported having smoked at least
Comorbid conditions and sociodemographic character- 100 cigarettes during their lifetime and who reported pres-
istics. Data on 17 individual, dichotomous (yes/no) self- ently smoking every day or some days. Heavy drinkers
reported conditions were categorized into 5 mutually ex- were dened as men who reported drinking 2 drinks per
clusive groups. The respondent had a respiratory day and women who reported drinking 1 drink per day
condition if he or she had ever had an allergic reaction to (13). Persons were considered to be inactive if they never
food, odor, or medication; asthma; or emphysema or re- participated in light or moderate activities (exercise for at
ported chronic bronchitis or sinusitis in the previous 12 least 10 minutes that causes light sweating or a slight to
months. The respondent had a cardiovascular abnormality moderate increase in breathing or heart rate) or vigorous
if he or she had ever had coronary heart disease, angina, activity (exercise for at least 10 minutes that causes heavy
heart attack, stroke, hypertension, hypercholesterolemia, sweating or large increases in breathing or heart rate) dur-
or other heart disease. Gastrointestinal conditions in- ing their leisure time. Body mass index (BMI) was calcu-
cluded a report of ever having stomach, duodenal, or pep- lated as weight in kilograms divided by the square of the
tic ulcer, or inammatory bowel disease, irritable bowel, height in meters. Consistent with the National Heart, Lung,
or severe constipation. Chronic pain and musculoskeletal and Blood Institute, persons were considered overweight/
conditions included ever having arthritis, reported facial obese if their BMI was 25 kg/m2 (14).
ache or pain in the jaw muscles or the joint in front of the
ear, or migraines or severe headaches in the previous 3 Statistical analysis. SUDAAN software, version 9 (Re-
months. Other chronic conditions included cancer, diabe- search Triangle Institute, Research Triangle Park, NC) was
tes, hypothyroidism or hyperthyroidism, neuropathy, or used in the analyses to account for the complex sample
seizures. A separate variable represented the total number design and to calculate prevalence estimates, 95% con-
of conditions (range 0 17) reported across these 5 catego- dence intervals, unadjusted odds ratios (ORs), and ad-
ries. Therefore, comorbidity status was represented in 2 justed ORs. In all analyses the alpha level for statistical
658 Strine and Hootman
Table 1. Prevalence of low back pain, neck pain, and both conditions in the previous 3 months among US adults ages >18
years, by selected sociodemographic characteristics: National Health Interview Survey, 2002*
Low back pain only Neck pain only Both neck and low back pain
Characteristic (n 34 million) (n 9 million) (n 19 million)
* Values are the 90% and 95% condence interval. GED general equivalency diploma.
Number is weighted to the US population using standardized statistical weights from the National Center for Health Statistics.
Signicant pairwise t-tests as compared with the rst level of each variable.
signicance was set at P less than 0.05. Respondents with- neck pain, we adjusted for sociodemographic characteris-
out complete information on low back and neck pain (n tics and number and type of comorbidity.
78) and those without complete information about socio-
demographic characteristics (sex, age, race/ethnicity, edu- RESULTS
cation, marital status, and employment status; n 548)
and comorbid conditions (n 590) were excluded from Prevalence estimates and sociodemographic character-
the analysis, yielding a total of 29,828 respondents avail- istics. Approximately 17.0% of adults ages 18 years re-
able for analysis. ported LBPO in the previous 3 months, 4.4% reported
First, we calculated the unadjusted prevalence of LBPO, NPO, and 9.3% reported LBPNP (Table 1). In general,
NPO, and LBPNP overall and by sociodemographic char- LBPO, NPO, and LBPNP were more common among the
acteristics and tested for signicant sociodemographic dif- older age groups, women, and white non-Hispanics. As
ferences among those with LBPO, NPO, and LBPNP using educational attainment increased, the prevalence of LBPO
pairwise t-tests (Table 1). Second, we calculated percent- and LBPNP decreased; however, the opposite was true for
ages and odds, unadjusted and adjusted, of comorbid con- persons with NPO. Persons never married were signi-
ditions (Table 2), psychological factors (Table 3), and cantly less likely to report LBPO, NPO, and LBPNP than
health behaviors (Table 4) among persons with LBPO, those married, and those previously married were signi-
NPO, LBPNP, and neither condition using logistic regres- cantly more likely than those married to report LBPNP and
sion modeling. To examine the association between co- LBPO, although the difference between those currently
morbid condition and low back and neck pain, we ad- married and previously married with regard to LBPO was
justed for potential confounding sociodemographic negligible. Finally, persons who formerly worked were
characteristics. To examine the association between psy- signicantly more likely to report LBPO and LBPNP than
chological factors, health behaviors, and low back and those who were currently working, whereas persons who
Back and Neck Pain, Mental Distress, and Behaviors 659
Table 2. Percentages and adjusted odds of comorbid conditions among US adults ages >18 years by reported lower back or
neck pain status: National Health Interview Survey, 2002*
Respiratory conditions
Allergy to food, odors, or medication (ever)
% (95% CI) 13.7 (13.214.3) 22.7 (21.424.1) 25.2 (22.428.2) 32.5 (30.534.5)
OR (95% CI) Referent 1.9 (1.72.0) 2.1 (1.82.5) 3.0 (2.73.3)
Adjusted OR (95% CI) Referent 1.8 (1.61.9) 1.9 (1.62.3) 2.7 (2.53.0)
Asthma (ever)
% (95% CI) 8.6 (8.19.2) 13.6 (12.514.8) 13.0 (11.115.2) 19.3 (17.821.0)
OR (95% CI) Referent 1.7 (1.51.9) 1.6 (1.31.9) 2.5 (2.22.9)
Adjusted OR (95% CI) Referent 1.7 (1.51.9) 1.6 (1.42.0) 2.5 (2.22.8)
Chronic bronchitis (previous 12 months) or
emphysema (ever)
% (95% CI) 3.6 (3.33.9) 8.3 (7.49.2) 6.9 (5.58.7) 13.3 (11.914.8)
OR (95% CI) Referent 2.4 (2.12.8) 2.0 (1.52.6) 4.1 (3.54.7)
Adjusted OR (95% CI) Referent 2.1 (1.82.4) 1.8 (1.42.3) 3.2 (2.83.7)
Sinusitis (previous 12 months)
% (95% CI) 10.5 (10.011.0) 18.9 (17.620.2) 23.6 (20.926.4) 30.0 (28.132.0)
OR (95% CI) Referent 2.0 (1.82.2) 2.6 (2.33.1) 3.7 (3.34.1)
Adjusted OR (95% CI) Referent 1.9 (1.72.1) 2.3 (2.02.8) 3.4 (3.03.7)
Cardiovascular abnormalities
Coronary heart disease, angina, heart attack,
stroke, other heart disease (ever)
% (95% CI) 9.5 (9.110.0) 16.3 (15.217.5) 18.0 (15.920.3) 20.6 (19.022.2)
OR (95% CI) Referent 1.9 (1.72.1) 2.1 (1.82.4) 2.5 (2.22.7)
Adjusted OR (95% CI) Referent 1.7 (1.51.9) 2.0 (1.72.3) 2.2 (2.02.5)
Hypertension (ever)
% (95% CI) 20.7 (20.021.3) 30.0 (28.531.5) 30.8 (27.933.8) 35.1 (33.137.2)
R (95% CI) Referent 1.7 (1.51.8) 1.7 (1.52.0) 2.1 (1.92.3)
Adjusted OR (95% CI) Referent 1.5 (1.41.7) 1.6 (1.31.9) 1.9 (1.72.1)
Hypercholesterolemia (ever)
% (95% CI) 17.7 (17.018.3) 25.2 (23.726.7) 27.8 (25.130.7) 30.8 (29.032.7)
OR (95% CI) Referent 1.6 (1.41.7) 1.8 (1.62.1) 2.1 (1.92.3)
Adjusted OR (95% CI) Referent 1.5 (1.31.6) 1.6 (1.41.9) 1.9 (1.82.1)
Gastrointestinal conditions
Stomach, duodenal, or peptic ulcer (ever)
% (95% CI) 5.1 (4.75.4) 11.3 (10.412.4) 11.2 (9.413.3) 18.0 (16.319.8)
OR (95% CI) Referent 2.4 (2.12.7) 2.4 (1.92.9) 4.1 (3.64.7)
Adjusted OR (95% CI) Referent 2.2 (1.92.4) 2.1 (1.72.7) 3.5 (3.14.0)
Inammatory bowel disease, irritable bowel, or
constipation severe enough to require
medication (ever)
% (95% CI) 3.4 (3.13.7) 7.3 (6.58.1) 11.2 (9.413.2) 14.6 (13.216.1)
OR (95% CI) Referent 2.2 (1.92.6) 3.6 (2.94.4) 4.8 (4.25.6)
Adjusted OR (95% CI) Referent 2.0 (1.72.3) 3.1 (2.53.8) 4.1 (3.54.8)
Chronic pain and musculoskeletal conditions
Facial ache or pain in jaw muscles or the joint
in front of the ear (previous 3 months)
% (95% CI) 1.9 (1.72.1) 5.6 (4.96.5) 11.8 (10.013.9) 19.4 (17.721.3)
OR (95% CI) Referent 3.1 (2.53.8) 7.0 (5.68.7) 12.6 (10.614.9)
Adjusted OR (95% CI) Referent 3.0 (2.43.7) 6.9 (5.58.7) 11.3 (9.413.5)
Migraine or severe headache (previous 3
months)
% (95% CI) 8.6 (8.19.0) 21.9 (20.623.3) 29.7 (27.032.6) 44.1 (42.046.2)
OR (95% CI) Referent 3.0 (2.73.3) 4.5 (3.95.2) 8.4 (7.69.3)
Adjusted OR (95% CI) Referent 3.1 (2.83.4) 4.8 (4.15.6) 8.6 (7.89.6)
Arthritis (ever)
% (95% CI) 13.8 (13.214.4) 31.2 (29.832.6) 35.1 (32.238.0) 46.2 (44.048.5)
OR (95% CI) Referent 2.8 (2.63.1) 3.4 (3.03.8) 5.4 (4.95.9)
Adjusted OR (95% CI) Referent 2.8 (2.63.1) 3.4 (2.93.9) 5.7 (5.16.4)
(continued)
660 Strine and Hootman
Table 2. Percentages and adjusted odds of comorbid conditions among US adults ages >18 years by reported lower back or
neck pain status: National Health Interview Survey, 2002* (Continued)
never worked were signicantly less likely than those who graphic characteristics and number and type of comorbid
were currently working to report LBPO and NPO. conditions, adults with LBPO, NPO, and LBPNP were
signicantly more likely than adults with neither condi-
Comorbidities. After adjusting for sociodemographic tion to report nervousness, restlessness, and a feeling that
characteristics, with the exception of diabetes, which was everything required effort all or most of the time in the past
equally prevalent in persons with NPO and those with 30 days (Table 3). However, adults with NPO were no
neither condition, we found the remaining respiratory, more likely to report sadness, hopelessness, or worthless-
cardiovascular, gastrointestinal, chronic pain and muscu- ness than were adults with neither condition. These con-
loskeletal conditions, and other chronic conditions to be ditions were most prevalent among persons with LBPNP.
signicantly more prevalent among those with LBPO, Overall, persons with LBPO were 1.8 times more likely
NPO, and LBPNP than those with neither condition (Table than those with neither low back pain nor neck pain to
2). The prevalence of individual comorbid conditions was have potential serious mental illness, those with NPO
consistently highest among individuals with LBPNP. No- were 1.7 times more likely, and those with LBPNP were
tably, adults with NPO were signicantly more likely than 3.4 times more likely.
those with LBPO to report sinusitis in the previous 12
months; inammatory bowel disease, irritable bowel, or Health behaviors. After adjusting for sociodemographic
constipation severe enough to require medication; facial characteristics and number and type of comorbid condi-
ache or pain in the jaw muscles or the joint in front of the tions, individuals with LBPO were signicantly more
ear in the previous 3 months; and migraines or severe likely to smoke (adjusted OR 1.3), to be overweight or obese
headaches in the previous 3 months. (OR 1.2), and to drink heavily (OR 1.3) than those with
neither low back pain nor neck pain. Moreover, those with
Psychological factors. After adjusting for sociodemo- NPO were signicantly more likely than those with neither
graphic characteristics and number and type of comorbid condition to drink heavily (OR 1.5); however, persons with
conditions, we found that persons with LBPO, NPO, and NPO were signicantly less likely than those with neither
LBPNP were signicantly more likely than those with low back or neck pain to be physically inactive (OR 0.8).
neither condition to report frequent depressive or anxiety Finally, individuals with LBPNP were signicantly more
symptoms, insomnia or trouble falling asleep, excessive likely than those with neither condition to smoke (OR 1.5).
sleeplessness during the day, and recurrent pain during
the previous 12 months (Table 3). These conditions were
DISCUSSION
more prevalent among individuals with LBPNP than those
with LBPO or NPO. To our knowledge, these are the rst national prevalence
Among the K6 domains, after adjusting for sociodemo- estimates of low back and neck pain in the US adult
Back and Neck Pain, Mental Distress, and Behaviors 661
Table 3. Percentages and odds of selected psychological factors among US adults ages >18 years by reported lower back or
neck pain status: National Health Interview Survey, 2002*
Table 4. Percentages and adjusted odds of selected health behaviors among US adults ages >18 years by reported lower back
or neck pain status: National Health Interview Survey, 2002*
Neither low back nor Low back pain Both lower back
Characteristic neck pain only Neck pain only and neck pain
* 95% CI 95% condence interval; OR odds ratio; BMI body mass index.
Adjusted by age, sex, race/ethnicity, education, marital status, employment status, and number and type of comorbid condition.
population. Our results indicate that low back and neck pain (35,36). However, the current literature suggests that
pain are major public health problems in the US because smoking is potentially associated with the incidence and
more than 34 million (17%) adults reported LBPO, 9 mil- prevalence of nonspecic back pain (3739), intervertebral
lion (4%) reported NPO, and 19 million (9%) reported disc disorders (40), and neck pain (17), as well as chronic
LBPNP in the previous 3 months. Not only does our study widespread musculoskeletal pain (41). In fact, a clear
corroborate previous research suggesting an association dose-response effect has been reported between the num-
between low back and neck pain, depressive and anxiety ber of cigarettes smoked daily and prevalence of low back
symptoms (1530), fatigue (31), and sleep impairments pain (41). Additionally, in a study of identical twins, ana-
(32,33), it also suggests that persons with LBPO, NPO, and lysis revealed 18% higher disc degeneration scores in the
LBPNP are signicantly more likely than those without lumbar spines of smokers as compared with nonsmokers
either condition to have potential serious mental illness, (42). Other reports (37,39,41) have postulated additional
even after adjustment for number and type of comorbid explanations for the association between smoking and
conditions and sociodemographic characteristics. LBPO, NPO, and LBPNP such as physiologic and meta-
As much as 16% of low back pain in the general popu- bolic processes and the presence of other behavioral con-
lation may be attributable to psychological distress (23). ditions.
Notably, a recent review article suggested that psycholog- We also found that persons with LBPO and NPO were
ical factors are more important than most biomedical or signicantly more likely than those with neither condition
biomechanical factors in the development of pain and to drink heavily (i.e., 2 drinks per day for men and 1
disability (18). Depression, which is highly prevalent drink per day for women; ORs 1.3 and 1.5, respectively).
among persons with chronic pain (24,25), is a strong inde- Very little research has examined these associations, and
pendent risk factor for the onset of disabling neck and low the research that has been conducted has produced incon-
back pain (23,26 30). Additionally, persons with depres- sistent results. Leboeuf-Yde suggests that alcohol con-
sive symptoms often have a lower threshold for pain and sumption is not associated with low back pain (43); how-
report greater functional impairment than those without ever, other research has found an association between pain
depressive symptoms (34). In fact, the combination of and drinking in older adults (44). Notably, similarly to
chronic back pain and major depression is associated with patterns of tobacco use, a signicant proportion of patients
greater disability than is either condition alone (24). with chronic pain have a history of alcohol abuse before
Our research also indicates that persons with LBPO and the onset of pain (45).
LBPNP are signicantly more likely than persons with Our results are strikingly similar to results reported by
neither condition to smoke. It is surmised that smoking Webb et al in a similar cross-sectional population-based
may be used as a coping mechanism by alleviating anxiety, study in the UK (46). They reported a 1-month prevalence
inducing relaxation, and distracting attention away from of 29% for a combination of back and neck pain, whereas
Back and Neck Pain, Mental Distress, and Behaviors 663
we reported a 3-month prevalence of 31% (LBPO, NPO, adult respondents included in this report are therefore a
and LBPNP). However, the range of prevalence estimates valid, representative sample of the US population ages 18
for similar conditions reported in other community-based years and older. Sampling and interviewing are continu-
and clinical population studies varies considerably. In a ous throughout each year and the annual response rate of
systematic review (47), the point prevalence of low back the NHIS is 90% of the eligible households in the sam-
pain ranged from 12% to 33%, 1-year prevalence ranged ple. The survey instrument is standardized, cognitively
from 22% to 65%, and lifetime prevalence ranged from tested, and administered according to strict protocol. Data
11% to 84%. This nding is likely due to many factors collectors are extensively trained and monitored for qual-
including varying case denitions of back and neck pain, ity control. Few clinical and community-based studies
different referent populations, study designs and data col- have these strengths; subsequently, these data are an im-
lection methods, and the use of various referent time pe- portant contribution to the literature on the epidemiology
riods (point in time, 1 year, lifetime, etc.) for prevalence of low back and neck pain in the US.
estimation (47). The eld would benet tremendously by Back and neck pain are complex conditions that involve
the development and validation of a consistent surveil- an interaction of biologic, social (interpersonal, economic,
lance case denition for monitoring population burden occupational, etc.) (34), and psychological (depression,
and evaluating prevention effectiveness as has been done anxiety disorders, somatization, personality disorders,
for self-reported doctor-diagnosed arthritis (48). etc.) factors (1530), as well as coping skills (51). Impair-
Both our study and the study by Webb et al (46) found ments in any of these domains likely contribute to the
that overweight/obesity was associated with back pain and onset and chronicity of back and neck pain. Our study
not neck pain after adjusting for sociodemographics and identied some modiable psychological factors and
comorbid conditions. While comorbidity may play a large health behaviors associated with back and neck pain and
role in the associations between LBPO, LBPNP, and over- our results suggest that further research should be multi-
weight/obesity, weight loss is an important back pain in- dimensional and aim to reduce mental distress and rein-
tervention. Notably, studies of bariatric surgery patients force benecial health behaviors in this population. Vari-
with low back pain have reported vast improvements in ous interventions that address physical and psychological
pain and disability, and in some cases low back pain has factors have been shown to be effective for low back and
completely resolved with weight loss (49,50). As obesity neck pain as well as general pain syndromes and include
rates continue to increase in the US, it is reasonable to exercise therapy, spinal manipulation and mobilization,
assume that the prevalence of back pain and its associated back schools, mind-body therapies, and multidisciplinary
comorbidity in the population will continue to increase. treatments (5255). Moreover, expanded assessment of
Our study has several limitations. First, NHIS is unable low back pain and neck pain in the general population
to identify sites of pain, or pain patterns (e.g., radiating), may provide a better understanding of both the prevalence
with the specicity of clinical samples. For example, it is of these conditions and the extent of their implications.
unclear how a respondent with pain in the thoracic region
would respond to the 2 case denition questions regarding
site of pain used in this study. Additionally, there is no AUTHOR CONTRIBUTIONS
information about the severity or duration of the subjects Ms Strine had full access to all of the data in the study and takes
low back or neck pain. Second, the data were based on self responsibility for the integrity of the data and the accuracy of the
reports and were not validated by physical or psychiatric data analysis.
Study design. Strine, Hootman.
examination. However, pain and psychological distress Acquisition of data. Strine.
are subjective experiences and can only be gathered by self Analysis and interpretation of data. Strine, Hootman.
report. Third, the time references for variables of interest Manuscript preparation. Strine, Hootman.
are different. Psychological and physical distress are ref- Statistical analysis. Strine.
erenced to the previous 12 months, K6 is referenced to the
previous 30 days, and the low back and neck pain ques-
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