MCQs On Autoimmunity

AUTOIMMUNITY
SANJAY KUMAR UPADHYAY
(INTERN-2012-13)
1.Which of the following is an oral manifestation of lichen planus?
a)Dentinogenesis imperfecta b)Fordyce spots
b)White chalky enamel surface d)White radiating lines on the buccal mucosa
Ans)d[shafer 7th ed 809]
2.Antinuclear antibodies are seen in
a)SLE b)Systemic sclerosis
c)Morphea d)All of the above
Ans)a[shafer 7th ed 806]
3.Which of the following is absent in CREST syndrome
a)Calcinosis cutis b)Raynauds phenomenon
c)Telangectasis d)Endocrine disorders
4.Nikolskys sign is positive in
a)Bullous pemphigus b)Epidermolysis bullosa
c)Herpes simplex d)Erythema multiforme
5.MONROs abscess are seen in
a)Pemphigus b)Lichen planus
c)Leukoplakia d)Psoriasis
1
6.In lichen planus the basal cells which are shrunken with an eosinophilic cytoplasm and with a
pyknotic and fragmented nuclei are called
a)Tzanck cells b)Civatte bodies
c)Donovan bodies d)Rushton bodies
Ans)b[shafer 7th ed 810]
7.Which of the following is not a type of lichen planus
a)Atrophic b)Hypertrophic
c)Verrucous d)Erosive
Ans)c[shafer 7th ed 809]
8.Tzanck smear test is used in the diagnosis of
a)Pemphigus b)ANUG
c)Apthous disease d)Lichen planus
9.Koebners phenomenon is seen with
a)Erythema multiforme b)Pemphigoid
c)Psoriasis d)Impetigo
Ans)c[burkets 10th ed 298]
10.Erythema multiformae is
a)An acute self limiting disease b)Painless vesicular self limiting disease
c)A viral disease d)Bacterial infection
2
11.Pemphigus is characterized by
a)Acanthosis b)Acantholysis
c)Hyperorthokeratosis d)Hyperparakeratosis
12.L.E cell phenomenon in peripheral blood is seen in
a)Rheumatic heart disease b)Infective endocarditis
c)Ischemic heart disease d)SLE
13.Lichenoid reaction are mainly due to
a)Intake of certain drugs b)Betel nut chewing
c)Cigarette smoking d)Intake of alcohol
14.Intraepithelial vacuolation with formation of vesicle or bulla intraepithelially above the basal
layer is characteristically seen in
a)Candida albicans b)Bullous pemphigoid
c)Pemphigus d)Lichen planus
15.Immunoflourescence test is positive in
a)Psoriasis b)Pemphigus vulgaris
c)Lupus erythematosus d)Scleroderma
Ans)b&c[shafer 6th ed 818]
3
16.Immunoflourescence is seen at basement membrane as patchy distribution in
a)Lichen planus b)Pemphigus
c)Pemphigoid d)Lupus erythematosus
17.Erosive lichen planus resembles which of the following
a)Monilial gingivitis b)Desquamative gingivitis
b)Herpetic gingivitis d)Acute ulcerative gingivitis
18.Target lesions are observed in case of
a)Erythema multiforme b)Lichen planus
c)Pemphigus vulgaris d)Psoriasis
19)Intraepithelial bulla are found in
a)Pemphigus b)Bullous pemphigoid
c)Bullous lichen planus d)Pemphigoid
20.Lichen planus
a)Can undergo malignant change b)Treated only by medication
c)Must be excised d)Is an idiosyncrasy reaction
4
21.Oral lesions are not seen in
a)Psoriasis b)Pemphigoid
c)Steven Johnson syndrome d)Candidiasis
22.Oral, ocular and genital lesions are seen in
a)Erythema multiforme b)Steven Johnson syndrome
c)SLE d)None of the above
23)Wickhams striae are seen in
a)Lichen planus b)Leukoplakia
c)Leukoedema d)Erythema multiforme
24.White radiating lines can be observed in case of lesions of
a)Lichen planus b)Erythema multiforme
c)Pemphigus d)Leukoplakia
25.Primary lesion in lichen planus is
a)Macule b)Papule
c)Vesicle d)Bulla
5
26.Bullae formation after striking an intact skin/mucosal surface is known as
a)Tinels sign b)Babinskis sign
c)Nikolskys sign d)Chovsteks sign
27.Lupus erythematosus is
a)Reactive lesion b)Degenerative condition
c)Autoimmune disorder d)Neoplastic condition
28.Psoriasis is associated with
a)Geographic tongue b)Benign median rhomboid glossitis
c)Lupus erythmatosus d)Lupus vulgaris
29.Formation of multiple pinpoint bleeding spots on scratching the skin is characteristic of
a)Pemphigus vulgaris b)Lupus erythematosus
c)Psoriasis d)Herpangina
30.Steven-johnson syndrome involves
a)Type I hypersensitivity reaction b)Type II hypersensitivity reaction
c)Type III hypersensitivity reaction c)Type IV hypersensitivity reaction
6
31.A 3 year old patient has extensive vesicles on lip,tongue,oral mucous membrane. After 2-4
days vesicles rupture at followed by pseudomembrane formation and also some dental lesions
seen what will be the diagnosis
a)Herpetic stomatitis b)EM
c)ANUG d)Steven Johnson syndrome
32.The primary cause of acantholysis in pemphigus vulgaris is
a)Autoimmunity b)Intercellular edema
c)Intraepithelial edema d)Chronic alcoholism
33.Histological clefts in lichen planus are
a)Civatte bodies b)Wickhams straie
c)Max-Joseph spaces d)Auspitzs sign
34.The swollen degenerating epithelial cell due to acantholysis is
a)Antischow cell b)Tzanck cell
b)Ghost cell d)Prickle cell
35.Pathological calcification is seen in
a)Scleroderma b)Lichen planus
c)Dystrophic epidermolysis bullosa d)Lupus erythematosus
7
36.Psoralane ultra violet A therapy is advised in
a)Pemphigus vulgaris b)Apthous ulcer
c)Carcinoma in situ d)ANUG
Ans)a[burkets 10th ed 70]
37.Subepithelial vesicles are characteristic all of the following except
a)Bullous pemphigoid b)Cicatricial pemphigoid
c)Pemphigus d)Epidermolysis bullosa acquisita
38.Hydropic degeneration of the basal cell of the stratum germinativum is a feature of
a)Leukoplakia b)Lichen planus
c)Syphilis d)Pemphigus
39.Butterfly rash is typically seen in
a)Herpes simplex b)SLE
c)Scleroderma d)None of the above
40.Which one of the following is not a lichenoid reaction
a)Graft versus host disease b)Fixed drug eruption
c)Pemphigus vulgaris d)Secondary syphilis
Ans)c[burket 11th ed 89,95]

MCQs On Autoimmunity

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AUTOIMMUNITY

SANJAY KUMAR UPADHYAY

1.Which of the following is an oral manifestation of lichen planus?

a)Dentinogenesis imperfecta b)Fordyce spots

Ans)d[shafer 7th ed 809]

2.Antinuclear antibodies are seen in

a)SLE b)Systemic sclerosis

c)Morphea d)All of the above

Ans)a[shafer 7th ed 806]

3.Which of the following is absent in CREST syndrome

a)Calcinosis cutis b)Raynauds phenomenon

c)Telangectasis d)Endocrine disorders

Ans)d[shafer 7th ed 839]

4.Nikolskys sign is positive in

a)Bullous pemphigus b)Epidermolysis bullosa

c)Herpes simplex d)Erythema multiforme

Ans)a[shafer 7th ed 825]

5.MONROs abscess are seen in

a)Pemphigus b)Lichen planus

Ans)d[shafer 7th ed 813]

a)Tzanck cells b)Civatte bodies

c)Donovan bodies d)Rushton bodies

Ans)b[shafer 7th ed 810]

7.Which of the following is not a type of lichen planus

Ans)c[shafer 7th ed 809]

8.Tzanck smear test is used in the diagnosis of

c)Apthous disease d)Lichen planus

Ans)a[shafer 7th ed 826]

9.Koebners phenomenon is seen with

a)Erythema multiforme b)Pemphigoid

Ans)c[burkets 10th ed 298]

c)A viral disease d)Bacterial infection

Ans)a[shafer 7th ed 814]

Ans)b[shafer 7th ed 826]

12.L.E cell phenomenon in peripheral blood is seen in

a)Rheumatic heart disease b)Infective endocarditis

c)Ischemic heart disease d)SLE

Ans)d[shafer 7th ed 821]

13.Lichenoid reaction are mainly due to

a)Intake of certain drugs b)Betel nut chewing

c)Cigarette smoking d)Intake of alcohol

Ans)a[shafer 7th ed 680]

a)Candida albicans b)Bullous pemphigoid

c)Pemphigus d)Lichen planus

Ans)c[shafer 7th ed 826]

15.Immunoflourescence test is positive in

a)Psoriasis b)Pemphigus vulgaris

c)Lupus erythematosus d)Scleroderma

Ans)b&c[shafer 6th ed 818]

a)Lichen planus b)Pemphigus

c)Pemphigoid d)Lupus erythematosus

Ans)c[shafer 7th ed 810]

17.Erosive lichen planus resembles which of the following

a)Monilial gingivitis b)Desquamative gingivitis

b)Herpetic gingivitis d)Acute ulcerative gingivitis

Ans)b[shafer 7th ed 809]

18.Target lesions are observed in case of

a)Erythema multiforme b)Lichen planus

c)Pemphigus vulgaris d)Psoriasis

Ans)a[shafer 7th ed 815]

19)Intraepithelial bulla are found in

a)Pemphigus b)Bullous pemphigoid