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Abstract
Introduction
Ulcerative colitis is a chronic inflammatory disease of the colon, especially concerning the
mucosal part of the colon. This disease is one of the inflammatory bowel diseases (IBD), which
until now has not known the cause clearly The cause of IBD is still unclear, but related to genetic
factors and environmental factors as a trigger this is evident from 10-20% of patients must have
family members affected by the same disease. Ulcerative colitis includes autoimmune diseases
related to the inflammatory response of bacteria in the colon. Broadly speaking IBD consists of 3
types, namely ulcerative colitis, Crohn's disease, and if it is difficult to distinguish between the two,
it is included in the category of indeterminate colitis Ulcerative colitis is one of two types of
Inflammatory Bowel Disease, in addition to Crohn disease. (Guslandi,1999).
People who do not smoke have a great potential with Collis ulcerative disease compared to
smokers. This is because toxins called Nitric Oxide in Nicotine can reduce the activity of circular
muscle activity, the release of nitrate in the intestinal wall can also ward off inflammatory bowel
disease. (Guslandi,1999).
Discussion
Ulcerative colitis is a chronic inflammation of colon that causes ulceration. Ulceration and
inflammation of the lining of the colon causes symptoms of abdominal pain, diarrhea, and rectal
bleeding. This condition is associated with intestinal inflammation called Crohn's disease
(Guslandi,1999).
Ulcerative colitis and Crohn's disease are chronic conditions that can last for years to decades,
beginning during adolescence and early adulthood or childhood. Inflammation in the colon also
causes the bowel is often empty, causing diarrhea. Ulcerative colitis is an inflammatory bowel
disease or IBD (Jugde,2003)
Tobacco chemical content that has been identified amounted to 2,500 components. 1,400
others decomposed or split, acting with other components and forming new components and
forming new components all of which form approximately 4,800 chemical components in the
smoke. In tobacco chemical content included (Susilowati,2006).
Reference
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Susilowati, E. Y. 2006. Identifikasi nikotin dari Daun Tembakau kering dan Uji Efektifitas
Ekstrak Daun tembakau.Semarang : Universitas Negeri semarang
Jugde TA. Inflammatory Bowel Disease. In: Friedman SL, McQuaid KR, Grendell JH, 2003.
Current Diagnosis and Treatment in Gastroenterology. 2nd ed. International ed.: McGraw-
Hill; p. 108-30.