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LECTURER:
Ns.Leni Merdawati,M.Kep
NAME
NURSING FACULTY
ANDALAS UNIVERSITY
PADANG
2016/2017
CHAPTER I
INTRODUCTION
1.1.BACKGROUND
Disease of rheumatoid arthritis (RA) is one of the autoimmune disease in the form of
inflammatory arthritis in adult patients (Singh et al., 2015). Pain in people with RA Synovial
joints, on the part of the tendon sheaths, and exchanges will experience a thickening due to
an inflammation followed by erosion and destruction of bone of the bone around the joint
(Syamsuhidajat, 2010) to be able to cause the disability (Yazici & Simsek, 2010). However,
most of the ongoing chronic rheumatic diseases, namely, recovery and relapse repeatedly
causing damage to the joints permanently in people with RA (Muchid, 2006).
According to the Arthritis Foundation (2015), as much as 22% or more than 50 million
adults in the United States aged 18 years or more was diagnosed with arthritis. From these
data, about 3% or 1.5 million adults experience the RA (Arthritis Foundation, 2015). RA
occurs in 0.5-1% of the adult population in developed countries (Choy, 2012). The
prevalence of RA in Indonesia according to the results of research conducted by Nainggolan
(2010), the number of sufferers of RA in Indonesia year 2009 was 31.3% to 23.6%.
1.2. Purpose
RHEUMATOID ARTHRITIS
Rheumatoid athritis (RA) is one of the common conective tissue diseases and the most
destructive to the joints. It is a chronic,progressive,systemic inflammatory autoimmune
diseases process that affects primarily the synovial joints. Systemic means this disease affect
the body system, affecting many joints and other tissues. RA affect over 2 million people,
and European Americans have the disease more often than other groups.
In RA , autoantibodies ( rheumatoid factors [RFs]) are formed that attack healthy tissue,
especially syynovium causing inflammation. RFs consist mainly of immunoglobulins M and
G , and they bind with antigens forming immune complexe. Phatocytes attemp to engulf
these complexes and , as a results, release powerful enzymes, such as cytokines. The B and
T-lymphocytes of the immune system are also stimulates and increase the imflammatory
respone.
Rheumatoid arthritis is a systemic diseases, area of the body beside the synovial joint can
be affected. Inflammatory responses similar to those occuring in synovial tissue may be seen
in any organ or body system in which connective tissue prevalent. If blood vessel
involvement occurs, the organ suplied by that vessel can be affected. The result is
malfunction and eventual failure of the organ or system. Theses pathologic changes may
occurs late in the disease process and cause life theartening problems.
2.2. Risk Factors
The exact causes of RA are unknown, but research has shown that several factors may
contribute to its development:
1. Family history
Some people who develop RA have genetic risk factors. However, having genetic risk
factors for RA does not necessarily mean you will develop the disease.
2. Gender
RA affects women two to three times more often than men.
3. Hormones
There seems to be an increased risk of RA related to hormonal changes. For instance, RA
symptoms often improve during pregnancy, however, these women may experience a
flare up after delivery. RA is less common among women who breastfeed. Also, some
studies have even found that women whove used oral contraceptives had a modest
decrease in the risk of RA.
4. Age
Anyone can get RA at any age, but the risk does increase with age (commonly
developing between ages 40 and 60).
2.3. Pathophysiology
Rheumatoid athritis affects different people in different ways. Symptoms may slowly
develop over several years, or the disease may progress quickly. Symptoms may be mild or
very severe. You may go through phases called flares or flare-ups when symptoms are
severe. At other times, it may seem as if the disease and its symptoms have gone away. This
is called remission.Joint pain and swelling may happen slowly and may occur over weeks
or months. The small joints in the wrists and hands are often inflamed first. Over time, other
joints may be painful and swollen due to Rheumatoid athritis.
1. Medical history
Your doctor will ask about your personal and family medical history; recent and current
symptoms (pain, tenderness, stiffness, difficulty moving) when they started, if they come and
go, how severe they are and if anything makes them better or worse. The number and pattern
of joints involved can also indicate RA; the disease tends to affect the same joint on both
sides of the body. However, it is possible for the disease to develop in a single joint. RA
involves large and small joints, but typically starts in small joints, such as those in the hands
and feet.
2. Physical exam
Your doctor will examine each joint, looking for tenderness, swelling, warmth and
painful or limited movement. An overall physical exam may reveal other signs, such as
rheumatoid nodules or a low-grade fever.
3. Blood tests
Blood will be drawn for two types of tests. One measures inflammation levels. The other
looks for biomarkers such as antibodies (blood proteins) linked with RA.
4. Imaging tests
An X-ray, ultrasound or magnetic resonance imaging (MRI) scan may be done to look for
joint damage, such as erosions, a loss of bone within the joint and narrowing of joint space.
Their absence doesnt rule out RA, however. It may mean that RA is in an early stage and
hasnt yet damaged the joints. Early images can be compared to ones taken later to help
monitor how well treatment is work
2.6. Treatmens
1. Corticosteroids
Cortisol is a hormone produced naturally by the bodys adrenal glands that has many
functions in our bodies. One of cortisols important actions is its antiinflammatory function.
Cortisol can be considered the brake for the immune system, preventing it from
overreacting to infections, injuries and trauma. However, steroids have many potential long
term side effects. Therefore, they are often used as an interim measure to help control
inflammation while waiting for the slower-acting DMARDs to take effect or in the case of
someone experiencing a flare of inflammatory arthritis. Ideally, steroids should be used at
the lowest dosage that provides benefit for the shortest period of time.
DMARDs are a class of medications used to treat many different types of inflammatory
arthritis, such as RA, and work well for most people. The earlier a DMARD is started the
more effective it can be to suppress inflammation and prevent joint damage. It is important
to slow or even stop the progression of joint damage, but keep in mind that DMARDs
cannot fix joint damage that has already occurred.
3. Biologics
Biologics are drugs made from living cells (human, animal, bacteria, etc.). They are a
class of medications specially designed to treat inflammatory types of arthritis, such as RA.
Biologic medications work by modifying the bodys inflammatory response. Like
DMARDs, biologics can reduce pain, joint inflammation and damage to bones and cartilage.
A. Assessment
1. Identity
Including name, gender, age, address, religion, marital status, education, occupation,
register number, hospital admission date.
2. Main complain
3. History of the disease now
Data collection is done since complaints arise. In rheumatoid arthritis clients, the early
stages are usually characterized by generalized disorders such as malaise, weight loss,
fatigue, slight heat, and anemia. Local symptoms that occur in the form of swelling,
tenderness, and motion disorders in the metacarpophalangeal joint.
4. Past medical history
Is there a history of previous joint or bone disorders?
Has the patient undergone surgery such as joint replacement?
5. Family health history Assess whether there is a family of previous generations who have
the same complaint with clients.
6. Physical examination After anamnesis, physical examination is very useful to support
data history.
7. Diagnostic test Physicians rely on diagnostic tests to help them provide quality care to
people with RA. Diagnostic tests can take the form of blood analyses, joint fluid
analyses, urine analyses, and x-rays.
B. Nursing management
CONCLUSION
3.1.CONCLUSION
Rheumatoid athritis (RA) is one of the common conective tissue diseases and the most
destructive to the joints. It is a chronic,progressive,systemic inflammatory autoimmune
diseases process that affects primarily the synovial joints. . Inflammatory responses similar
to those occuring in synovial tissue may be seen in any organ or body system in which
connective tissue prevalent. If blood vessel involvement occurs, the organ suplied by that
vessel can be affected. The result is malfunction and eventual failure of the organ or system.
Theses pathologic changes may occurs late in the disease process and cause life theartening
problems.
REFERENCE
Donna D. Ignatavicius, M. Linda Workman.2009. Medical-Srgical Nursing: 6th Edition
Iain B. Mcinnes, F.R.C.P., Ph.D., And Georg Schett, M.D. 2011.The Pathogenesis Of
Rheumatoid Arthritis. United Kingdom
Gloria M. Bulechek, Howard K.Butcher, Dkk. 2013. Nursing Interventions Classification (Nic)
:6 Edition . Elseiver : United States Of America
Sue Moorhead, Marion Johnson, Dkk. 2013. Nursing Outcomes Classification (Noc) 5 Edition.
Elseiver : United States Of America