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EvaluationoftheAntibacterialActivityinPomegranatePeelsandArilsbyusingEthanolicExtractagainstSMutansandLAcidophilus
2014. Fatemeh Nikfallah, Adith Venugopa, Harsh Tejani & Hemanth T. Lakshmikantha. This is a research/review paper,
distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License
http://creativecommons.org/licenses/by-nc/3.0/), permitting all non-commercial use, distribution, and reproduction in any
medium, provided the original work is properly cited.
Evaluation of the Antibacterial Activity in
Pomegranate Peels and Arils by using Ethanolic
Extract against S. Mutans and L. Acidophilus
Fatemeh Nikfallah , Adith Venugopal , Harsh Tejani & Hemanth T. Lakshmikantha
Abstract- The use of antibiotics has revolutionized the against E. coli and B. subtilis. Also research has shown
treatment of various enteric bacterial infections. However, their
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that gallic acid has the highest antibacterial activity
indiscriminate use has led to an alarming increase in antibiotic against E. coli and B. subtilis and the antibacterial
resistance among microorganisms, thus necessitating the
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activity of the compounds was due to the structural
need for development of novel antimicrobials. Then main
objective of this study is to evaluate antibacterial activity of
similarities of the compounds (Naz et al., 2007).
pomegranate fruit extract on selected bacterial culture. Although studies shows Punica granatum has 1
Antibacterial activity of pomegranate was tested on MRS agar antibacterial potential against few bacterial strains but
there is lack of investigation on antibacterial property of
P
unica granatum is one of the oldest known
edible fruits. It has been widely used in
traditional medicine worldwide for the treatment
of different types of diseases (Olapour et al., 2010). Also
several antioxidant activities, including radical-
scavenging ability, ferrous ion chelating and ferric ion
reducing antioxidant power, were identified on P.
granatum.
Research showed low concentration of P.
granatum extract led to delay in S.aureus growth, while
in a higher concentration of P.granatum extract, growth
of S.aureus was eliminated (Braga et al., 2005). P.
granatum also has antibacterial activity against B.
subtilis, E. coli, S. aureus and Klebsiella (Fawole et al.,
2012). Investigation on the chemical composition of
pomegranate fruit led to identification of cyanidin-3-
glucose, quercetin, gallic acid, pelargonidin-3-
galactoseand myricetin which has antibacterial activity
2
Global Journal of Medical Research ( J ) Volume XIV Issue II Version I
Result showed combination of peels and arils has no inhibitory effect against selected organisms. But
extract has greater inhibitory effect. Result showed Arils result showed peels have inhibitory effect.
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S. mutans L. acidophilus
Global Journal of Medical Research ( J ) Volume XIV Issue II Version I
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S. mutans L. acidophilus S. mutans L. acidophilus S. mutans L. acidophilus
IV. Discussion the peels. Also result confirmed arils were not effective
in the inhibition of S. mutans and L. acidophilus.
Result showed combination of peels and arils
extract has greater inhibitory effect. Arils have no VI. Recommendations
inhibitory effect against selected organisms. Result Further study on antibacterial effect of seed
showed combination of peels and arils have greater extract in combination with juice and peels is
antibacterial effect than pure peel extract. Also result recommended. Also further study on antibacterial effect
showed combination of peels and arils have greater against wider range of oral bacteria is recommended.
antibacterial effect on L. acidophilus in comparison with
pure peel extract. Also result showed pure peel extract References Rfrences Referencias
has grater antibacterial effect on S. mutans in 1. Olapour S., H. Najafzadeh. Evaluation analgesic,
comparison with combination of peel: arils extract.