EFFECTS OF THE NUTRITIONAL

TRANSITION IN WOMEN WITH

PREGESTATIONAL DIABETES
Alessi, J; Wiegand, D; Hirakata, VN; Oppermann, MLR ; Reichelt, AJ
Servio de Endocrinologia; Servio de Ginecologia e Obstetrcia; Unidade de Bioestatstica.
Hospital de Clnicas de Porto Alegre

INTRODUCTION
Pregestational diabetes is associated
with potential adverse outcomes for the mother and
the newborn, which may depend on the epoch
women were treated, due to different standards of
care and maternal clinical characteristics across time.
OBJECTIVE
The objective was to evaluate clinical
characteristics of women across two periods of time.
METHODS
220 women attended in a specialized prenatal care
facility.
Clinical characteristics as weight, body mass index (BMI),
preeclampsia, cesarean section and newborn outcomes
were evaluated.
Epoch of care was stratified from 2005 until 2010 (period
1) and after 2010 (period 2).
Analyses were performed applying the Student's t-test
and the chi-square test and using the version18 of SPSS.

RESULTS Previous macrosomia (8.2% vs 20.5%, p=0.011) and previous

PE (9,2% vs 21,3%, p=0.015), as well as a BMI 25 kg/m2
Type 1 diabetes was more frequent in period 1 (56.5% vs (59,1% vs 78%, p=0.003) were more frequent in period 2.
43.5%) and was surpassed by type 2 DM in period 2 (63.0% vs There was a trend to a lower frequency of PE diagnosis
37.0%), p=0.005 (Table 1 and Figure) . (37,0%) vs 24,8%, p=0,055) in the second period.
Table 1. Types of pregestational diabetes in two periods of time Table 2. Comparison of some characteristics in pregestational diabetes
PERIOD across two periods of time
Diabetes type 2010 2011 Total

n (%) n (%)

Type 1 48 (56.5) 37 (43.5) 85 (39)

Type 2 50 (37.0) 85 (63.0) 135 (61)

Total 98 (44.5) 122 (55.5) 220 (100)

Figure: Trends in pregestational diabetes cases across time.

Hospital de Clnicas de Porto Alegre, 2005 - 2015. SD: standard deviation; N: number; HDP: hypertensive disorders of pregnancy

CONCLUSION
Nowadays, women in reproductive age are frequently diagnosed as having type 2 diabetes, in parallel
with the higher rates of obesity; even those with type 1 DM presented higher pre-gestational weight in the later time.
The nutritional transition is also reflected in women with pre-gestational diabetes.

Apoio: FIPE-HCPA, projeto 016/331.