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ABSTRAK

Nama : Phamella Esty Nuraini


Program Studi : Pendidikan Dokter
Judul : Perbandingan Nodul Tiroid pada Pemeriksaan Fine Needle
Aspiration Biopsy (FNAB) dengan Pemeriksaan
Histopatologi di RSUD Abdul Wahab Sjahranie Samarinda

Nodul tiroid termasuk kelainan tiroid yang paling sering terjadi. Nodul tiroid
bersifat ganas pada 10-15% kasus. Fine Needle Aspiration Biopsy (FNAB)
digunakan sebagai langkah diagnostik awal nodul tiroid. FNAB merupakan
prosedur yang sederhana, murah, cepat dilakukan, dan akurat. Penelitian bertujuan
mengetahui karakteristik nodul tiroid, sensitivitas, spesifisitas, nilai prediksi
positif, nilai predisi negatif, dan akurasi FNAB di RSUD Abdul Wahab Sjahranie
Samarinda. Penelitian observasional analitik dengan desain uji diagnostik
dilakukan pada 194 pasien nodul tiroid yang diperiksa dengan FNAB dan
histopatologi. Data bersumber dari rekam medis Laboratorium Patologi Anatomi
RSUD Abdul Wahab Sjahranie Samarinda periode 2010-2015. Hasil penelitian
menunjukkan perempuan lebih banyak menderita nodul tiroid. Usia 41-50 tahun
merupakan usia dengan pasien nodul tiroid terbanyak. Berdasarkan pemeriksaan
histopatologi ditemukan 169 (87,11%) kasus nodul tiroid jinak dan 25 (12,89%)
kasus nodul tiroid ganas. FNAB memiliki sensitivitas sebesar 76%, spesifitas
93,49%, nilai prediksi positif 63,33%, nilai prediksis negatif 96,34%, dan akurasi
91,24%. Disimpulkan bahwa FNAB memiliki nilai diagnostik yang baik untuk
mendiagnosis nodul tiroid.

Kata Kunci : nodul tiroid, FNAB, histopatologi, uji diagnostik

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ABSTRACT

Name : Phamella Esty Nuraini


Study Program : Medical Education
Title : The Comparison of Fine Needle Aspiration Biopsy (FNAB)
Diagnostic with Histophatlogical Biopsy Diagnostic of
Thyroid Nodule in RSUD Abdul Wahab Sjahranie
Samarinda

Thyroid nodule is the most common case of thyroid disorders. It is maliganant to


10-15% cases. Fine Needle Aspiration Biopsy (FNAB) is the first step diagnostic
procedure of thyroid nodule. It is very simple, low-cost, has a quick procedure to
perform and accurated. The study aimed to know the character of thyroid nodule,
sensitivity, spesificity, positive predictive value, negative predictive value, and
accuracy of FNAB in RSUD Abdul Wahab Sjahranie Samarinda. This is an
analytic observation study with diagnostic test design performed on 194 thyroid
nodules of patients that diagnosed by FNAB and histopathological biopsy. Data
was taken from anatomy pathology laboratoriums medical records of RSUD
Abdul Wahab Sjahranie Samarinda in the period of 2010-2015. Result showed
that the patients of thyroid nodules were generally women and people on their
ages 41-50. Based on histopathology, there were 169 benign nodules (87,11%)
and 25 malignant nodules (12,89%) among 194 nodules. Sensitivity, spesificity,
positive predictive value, negative predictive value, and accuracy of FNAB were
76%, 93,49%, 63,33%, 96,34%, and 91,24%. It was concluded that FNAB has a
good diagnostic value to diagnose thyroid nodule.

Keyword : thyroid nodule, FNAB, histopathology, diagnostic test

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