Cytokine Market

Cytokines are small secreted proteins released by cells that have a specific effect on the
interactions and communications cells. Cytokines may act on the cells from which they are
secreted (autocrine action), on nearby cells, and in some instances, on the distant cells (endocrine
actions).

Cytokines are produced by a broad range of cells, including cells of the immune system of the
human body, with respect to complex immune response. Cytokines helps in intercellular
communication in immune response, as they are cell signaling molecules, and thus, they trigger
the movement of cells on inflamed infection sites. Cytokines can be briefly categorized as peptides,
proteins, and glycoproteins. These, along with their receptors, are used in different treatment
therapies, inflammatory conditions, immune disorders, infectious diseases, and oncology to boost
immune response.

Keywords: Cytokines, immune system, cell signaling, cytokine market, proteins,

glycoproteins

Other names of cytokines?

 Many cytokines are referred to as “interleukins”, which indicate that they are secreted by
some leukocytes and act on other leukocytes
 Some are called “interferon” and “tumor necrosis factor”
 They are also known as growth factors
  Cytokines are also alternatively known as Chemokines. Chemokines play an important role
in inflammation.
 A group of cytokines are referred to as as colony-stimulating factors (CSF), which are
required for the growth and differentiation of blood cells from hematopoietic stem cells

Though cytokines help the immune system in various ways, they also have various adverse effects
as they are linked to many disease conditions, namely schizophrenia, major depression,
Alzheimer’s, and cancer, among others. Over-secretion of cytokines can trigger a syndrome known
as cytokine storm. Due to increasing cytokines levels, deaths were weighted more heavily toward
people with healthy immune system.

A report by Mordor Intelligence, a market research firm estimates double digit growth rate for
Global cytokine market

The growing interest in harnessing the immune system to eradicate cancer over the past two
decades has been accompanied by heightened efforts to characterize cytokines and exploit their
vast signaling networks to develop cancer treatments. They directly stimulate immune effector
cells and stromal cells at the tumor site, and enhance tumor cell recognition by cytotoxic effector
cells. Numerous animal tumor model studies have demonstrated that cytokines have a broad range
of anti-tumor activities, and this has been translated into a number of cytokine-based approaches
for cancer therapy.

Drivers for Cytokine Market: Contribution of cytokines in stem–cell therapy and increasing
acceptance of cytokines as a potential biomarker for neonatal sepsis are some of the factors driving
the cytokine market.

Hurdles for Cytokine Market are: Cytokines have inherently short half-life, which necessitates
prolonged administration of cytokine therapies. This is a major problem in maintaining an effective
dose over a long period. This becomes an even greater issue when cytokine is administered
systematically.

Way Ahead: Efficiency of cytokine therapies in treating cancer, asthma, and arthritis will likely
drive cytokine market in the future.
About the Author: Mitali Verma is working as a Research Associate with the Mordor
Intelligence, a market research and consulting firm based in Hyderabad, India, with expertise in
accurate research and analysis.