/o o
New edition
PharmaceuticalDosage
Forms: Disperse Systems,
2rid e d n
(Vois I a n d 2)
edited by Herbert A. Lieberman,
Martin M. Rieger and Gilbert S.
Banker, Marcel Dekker, 1996.
Vol. 1:$165.00 (xviii + 532
pages) ISBN 0 8247 9~87 0
Vol. 2:$165.00 (rx + 506 pages)
ISBN 0 8247 9713 2
This edition, revised and expanded,
is published about eight years after
the first and contains 25% new mate-
rial and several new chapters. The
second edition is now in three, as
opposed to two, volumes. A variety
of topics are covered, ranging from
the theory of suspensions, colloids
and emulsions to products such as
B ~ D ~ L is citedin so manypapersand posters,worldwide,
BiomedicalResearch and DeVelopmentLaboratories Inc., 8561 Atlas Drive, Gaithersburg, MD 20877 USA Phone: 301-948-6506
3 8 2 TiPS - O c t o b e r 1996 ( V o L 17)
pharmaceutical suspensions and
ophthalmic ointments. This short
description will highligl-.', some of
the changes incorporated into this
new edition.
Volume 1 (10 chapters) covers the-
oretical aspects involved in the for-
mulation of different types of dis-
perse system drug products, such as
suspensions, emulsions, aerosols
and ointments. Chapter 2, entitled
'Theory of Suspensions' covers the
characterization of suspension-type
products and includes a new section
on light-scattering techniques.
Chapter 3 on emulsions has been
expanded and the chapter on col-
loids, which now contains many
new references, has been updated.
'Bioavailability of Disperse Dosage
Forms' (Chapter 8) has been texten-
sively rewritten, reorganized and
enlarged. The final chapter (Chapter
10), on experimental design, model-
ling and optimization strategies is a
mathematical chapter that has been
1- t,~ll It ~ u t t t ~ a tU tlgl V ~ t U ~ ~Ota t.ttl! t U~tlt tt DItIIIU~I
for reliabilityand reproducibility.That'swhy Brandel
Twentyyearsof continuousrefinementhas resultedin
C o p y r i g h t © 1996, E l s e v i e r Science L t d . A l l r i g h t s r e s e r v e d . 0165 - 6 1 4 7 / 9 6 / $ 1 5 . 0 0
revised and updated and includes
statistical techniques and strategies
useful for pharmaceutical product
development.
Volume 2 (12 chapters) focuses on
specific types of disperse system
dosage forms. Chapter 1, on phar-
maceutical suspensions, includes
topics on stabilization and formula-
tion of suspensions and both theo-
rectical and practical aspects of sus-
pensions are covered. An important
change in this volume has come
from combining the chapters on
pharmaceutical emulsions and
microemulsions into one chapter,
which includes more than 250 refer-
ences. The chapter on antacids and
clay products (Chapter 3) contains
several new figures and also
includes information relating to the
testing and evaluation of antacid
suspensions.
Chapter 6, on reconstitutable sus-
pensions, also contains some modifi-
cations, the most significant being an
tU1 ~ l l l n a t c l l e U s e l e c u o n Ol- m o Q e l S , i o r m a l . s , o p u o u s
and accessoriesso that now youcan ordera custom
builtsystemat an off the shelfprice.
Precisionmanufactureand programmablecontrol
 B o o K s

addition of current information on suspensions, particularly in the area reworked and updated. It is antici-
stability evaluation of reconstituted of product safety and a new section pated that this new edition will
antibiotic oral suspensions, e.g. on the packaging aspects of oph- appeal to a cross section of the
determination of shelf-life at differ- thalmic ointments and suspensions scientific community, including
ent temperatures. Major revision has been added. Finally, Chapter 12 industrial pharmacists and scien~ts
has been undertaken on the cover- on supvository development and working in both academia and
age of ophthalmic ointments and production has been extensively government.

Academic Press, 1996. £35,00 (xvi + 156

Books r e c e i v e d
Books featured in the Books receivedsection will not be reviewed in Trends in
PharmacologicalSciences.
John N. Abelson (ed.) Methods in
El~zymology, Vol. 267, Combinatorial
Chemistry Academic Press, 1996. $85.00
(xxx + 493 pages) ISBN 0 12 182168 4
H. G. Brittain (ed,',' Analytical Profiles of
Dr~tg Substances and Excipients VoI. 24
Academic Press, 1996. $99.00 (xii + 619
pages) ISBN 0 12 260824 0
Gerald D. Fasman (ed.) Circular
Dichroism and the Canformational
Analysis of Biomolecules Plenum Press,
1996. $125.00 (x + 738 pages) ISBN 0 306
45142 5
J. Z. Knapp, T. A. Barber and A.
Lieberman (eds) Liquid- and Surface-
Borne Particle Measurement Handbook
Marcel Dekker, Inc,, 1996. $195.00
(viii + 915 pages) ISBN 0 8247 9386 2
Fred Mellon and Brittmarie SandstrOm
(eds) Stable Isotopes in Human Nutrition
pages) ISBN 0 12 490540 4
H. Motulsky (ed.) hstuitive Biastatistics,
Oxford Science Publications, 1995. £30,00
(xx + 386 pages) ISBN 0 19 508606 6
D. Raebum and M. A. Giembycz (eds)
Airways Smooth Muscle: Modelling the
Asthmatic Response In Vivo, Birkhauser
Verlag, 1996, £99.00 (xli + 276 pages)
ISBN 3 7643 5300 7
M, Yalpani (ed.) Biomedical Functions
and Biotechuology of Natural and Artificial
Polymers ATL Press, Inc., 1996..%245.00 (xii
+ 284 pages) ISBN 1 88~_36002 8
World Health Organization, Cancer Pain
Relief:. With a Guide to Opioid Availability,
World Health Organization, 1996. S15-30
(vi ÷ 63 pages) ISBN 92 4 154482 1

reproducible resulis time after time. But what of the future? HTS demands a higher level Europeanenquiriesto: . . . . . . . . .
The practical, open design lets you keep an ¢y¢ on of automation - that means robotics, b ~ ~ ~ l t
I aspiration and wash cycles while Teflon tubing The new Brande19600 system is already in place,
minimises sticky ligand a~erence, just add a rotx~tic ann.

Semat Technical (UK) Ltd., One Executive Park, Hatfield Rd, St. Albans. Hens. ALl 4TA. UK Tel: +44. (0)1727 841414

Copyright© 1996,ElsevierScienceLtd All rights reserved 0165- 6147/96/$15.00 TiPS - October 1996 (Vol. 17) 3 8 3