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THE PURPLE SEAL:: Breaking the Plague

of Chronic Diseases and Syndromes:

Vegan Diet Ancient Egyptian “School of On” (Annu or God) Sun Goddess
Het Heru High Priestess Holding a Duckling, Nakhet Tomb, Circa 1450 BC.

“The Great Pathophysiological


Ramifications of the Metabolisms of
Animal Dietary Cholesterol, Bile Acid,
DNA, Protein & Fat in the Aboriginal
Vegan Genotype Human Body”
By George W. Singleton, III
BA., HD., DD.
2007 and 2009 EUROPEAN UNION HUMANITARIAN GRANTEE

BRCA/Enlightenment Publications, Inc.

ISBN: 978-0-9741724-1-5 $10 (usd)


E-mail/Download International Edition 7€ (Euros)
THE PURPLE SEAL:: Breaking the Plague
of Chronic Diseases and Syndromes:

Vegan Diet Ancient Egyptian “School of On” (Annu or God) Sun Goddess
Het Heru High Priestess Holding a Duckling, Nakhet Tomb, Circa 1450 BC.

“The Great Pathophysiological


Ramifications of the Metabolisms of
Animal Dietary Cholesterol, Bile Acid,
DNA, Protein & Fat in the Aboriginal
Vegan Genotype Human Body”
By George W. Singleton, III
BA., HD., DD.
2007 and 2009 EUROPEAN UNION HUMANITARIAN GRANTEE

BRCA/Enlightenment Publications, Inc.


435 Spring Mill Lane
Indianapolis, IN. 46260
317-682-0142
gws@theuniversityofgod.org
http://www.theuniversityofgod.org/Page8.html

ISBN: 978-0-9741724-1-5
E-Mail/Download International Edition
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great
Pathophysiological Ramifications” of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA, Protein and Fat in the Aboriginal Vegan Genome Human Body”

Abstract

This Purple Seal by America’s 2007 & 2009 European Union Humanitarian Grantee BRCA, Inc. points
out that the 2009-10 historic public meeting debates and media analysis that finally led to passage of Health
Care Reform Legislation by the US Congress, predictably omitted the Health National Security Issue
that the major cause of the ever increasing health care costs in America is the failure to address properly
the complex etiology of the chronic diseases and syndromes. The key etiological role of
“animal/dietary cholesterol metabolism” including especially its derivative “bile acid metabolism” in the
chronic diseases and syndromes was omitted. Included are those of the Heart, the Cancers, Stroke,
Asthma, Emphysema, Bronchitis, Diabetes Mellitus, Alzheimer's, Influenza, Pneumonia, the Kidneys, the
Liver, Hypertension, Parkinson's, and Septicemia. In addition, as Amnesty International USA (AI-USA) has
identified America’s genocidal rate of maternal mortality as well its associated genocidal infant mortality
rate should be added to the list for “immediate amelioration.” Please see the AI-USA Press Release as
Appendix I-1.

Specifically, the systemic causation of the chronic diseases and syndromes is Animal/Dietary
Cholesterol and its related Animal DNA, Protein and Animal Fat residues acting as “slow poisons”
and simultaneously nutritionally supporting a chronic colonic pathogenic anaerobic bacterial infection
and chronic intestinal constipation generating blood transported organ inflammatory and autoimmune
reactions with cellular, tissue and organ toxemic necroses (deranged white blood cells and organ
death), mutagenesis (DNA genetic damage), atherogenesis (artery clogging and deformation),
cholelithgenesis (gall bladder, kidney and urinary bladder stones) and carcinogenesis (cancer).

This Purple Seal projects that since these chronic diseases and syndromes consumed in 2009 at least
65% of the nation’s annual $2.5 Trillion health care expenditures that the just established Health Care
Reform Legislation if implemented with proper Sickness Prevention Education and Practice Incentives
would save hundreds of thousands of lives and reduce health care costs annually by $600 Billion by 2012.
This saving would result from a properly sickness prevention educated public from whom it is predicted a
minimal ¼ of the nation’s people would make the properly informed dietary lifestyle change decision to
avoid ingesting Animal/ Dietary Cholesterol “pseudo” foods and to practice proper body cleansing
regimens to remove their unsanitary and pathogen supporting residues.

This Purple Seal invalidates the belief held by the Congressional Budget Office (CBO), many health care
industry experts and distinguished news media economic analysts that the prevention of sickness
component by the just established Health Care Reform Legislation would not generate significant health
care expenditure savings but instead would lead to further deficits.

Consequently, this Purple Seal proposes that since the previously requested convening of a 2010-2011 US
Select Committee on Human Nutrition and Human Needs and/or US House of Representative/Ways
and Means Committee Hearing is politically impossible now that the National Republican Party has
made the US Congressional passing of the Health Care Reform Bill a November, 2010 national election
issue and repeal target; that the White House Office of Health Care Reform endorse a Forum on
American Maternal and Infant Mortality Etiology and Possible Solutions sponsored by the
US/Department of Health and Human Services and moderated ideally by Dean Ornish, MD., Director,
Prevention Medicine Research Institute to address the complicated and controversial etiological roles of
Animal Dietary Cholesterol, Bile Acid, DNA, Protein and Fat Metabolisms in the aboriginal vegan
genotype human body.

It is predicted that the result of such a White House Office of Health Care Reform Forum would be
overwhelming bipartisan implementation of the presently bitterly opposed Health Care Reform Legislation
and its sickness prevention health education and practice incentives that is self-funding saving
minimally $600 Billion a year by the public and its present political opponents.

The National Security relevance of this “omitted health issue” is based on the fact that the ancient
Roman Empire and the modern Great Britain Empire fell in large part from within ignoring this issue
of breaking the law of nature in regards the aboriginal natural vegan (herbivore) diet of human beings
presented in the Bible Genesis 1: 29 (King James Version):

“And God said, Behold, I have given you every herb bearing seed, which is upon the face of all the earth,
and every tree, in the which is the fruit of a tree yielding seed; to you it shall be for meat.”

The Greek Father of Medical Writing Hippocrates VI of Cos (460 BC to 377 BC) wrote the maxim:

“Everyone has a doctor in him or her; we just have to help it in its work. The natural healing force within
each one of us is the greatest force in getting well. Our food should be our medicine. Our medicine
should be our food. But to eat when you are sick, is to feed your sickness.”
ii.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great
Pathophysiological Ramifications” of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA, Protein and Fat in the Aboriginal Vegan Genome Human Body”

CONTENTS
SECTION PAGE

O. Preface: 7/06/2010 Faxed Letter to US Department of State Secretary Hillary Rodman Clinton _____ 0

I. Introduction 1

II. Objective 1

III. The American Health National Security (HNS) Omission of “The Great
Pathophysiological Ramifications of Dietary Cholesterol & Bile Acids” ________________________ 1

A. The “Root Problems” of the American Health Care System _______________ 2


B. General Statistics – National __________________________________________ 3
C. Iatrogenic Disease and Iatrogenic Poverty Morbidity and Death _____________ 5
D. The “Background Noise” of the Cancer Epidemic _________________________ 6
E. The Top Fifteen Killers (TFK) of Americans in 1996, 2000 and 2006 ___________ 6

IV. Etiology of Animal/Dietary Cholesterol and Related Diseases and Syndromes (DCRDS) ___________ 8

A. Animal/Dietary Cholesterol is not a Human Dietary Requirement _____ _______ 8


B. Stereoisomer Specificity & Organic Steroid Chemistry of Cholesterol: ________ 8
C. Colorectal Cancer Cause ID & Connection to America’s High Fat Diet _______ 9
D. Secrets of Dietary Cholesterol and Bile Acid Metabolism __________________ 16
E. Obesity and the Occurrence of the Cancers and the Other DCRDS __ _____ 22
F. The “So-Called” Amino Acid Taurine and Bile Acid Metabolism ____________ 23
G. The Cholesterol Reducing Drugs and the Metabolic Syndrome ____________ 24
H. The Sanitation of the Human Body Blood Stream is the Key to Health _______ 26
I. Great Britain’s Prince of Wales Charles Warning to United
Arab Emeratus/Abu Dhabi about the Etiology of Diabetes Mellitus ___________ 28

V. The Human Body is Genome Genotype Vegan/Herbivore: Ramifications of


Dietary Cholesterol Liver Down Regulation ________________________________________________ 28

A. Overview of Scope and Impact __________________________________________ 28


B. Membrane Cholesterol Depletion ________________________________________ 29
C. Vitamin D3 Deficiency _________________________________________________ 30
D. Glucocorticoids Hormone Deficiency _____________________________________ 31
E. Mineralocorticoids Hormone Deficiency ___________________________________ 32
F1. Male Hormone Deficiency in the Male _____________________________________ 33
F2. Female Hormone Deficiency in the Female ________________________________ 34

VI. The Helicobacter Pylori Pathogen: First Formally Recognized Bacterial


Carcinogen and Gastro-Intestinal Pathogen _______________________________________________ 35

A. Exploits Animal Meat Ingesting Stomach with “Design from Hell” _____________ 35
B. Diseased Esophageal, Stomach and Duodenal Etiologies ____________________ 36
C. Prevention and Eradication _____________________________________________ 37

VII. The Implications for Caucasian Humans and for Other Omnivore Humans in the
Etiology and Prevention of Skin Cancer __________________________________________________ 38

A. The Genetic Mutation Loss of the Prehistoric Caucasian


Peoples’ Aboriginal Brown Skin Color __________________________________ 38
B. The Etiology of the Caucasian Peoples’ Skin Cancer: Highest Incidence
and Mortality of Any People in the World ________________________________ 40
C. The Analogy and Lesson To Be Learned From the Origin of the Polar Bear ____ 43
D. Prevention of Skin Cancer:: Inner Cleanliness and Natural Sun Tan __________ 43
E. Treatment of Skin Cancer:: Increase Endogenous Vitamin D Photosynthesis __ 43

VIII. Addressing the Genocidal Level of Infant and Maternal Mortality in America ____________________ 44

IX. The American Cancer Society, American National Cancer Institute’s AARP
and European Longitudinal Studies of “Meat Intake and Mortality ______________________________ 48

X. Misconceptions of Allopathic Medical Sciences, Education and Treatment ______________________ 49

XI. The Solution of Prevention of Sickness Education and Practice Incentives _____________________ 51

A. The Aboriginal Diet of Human Beings ___________________________________ 51


B. The 2010 USDA Food Group Pyramid Needs to Reflect
“Bile Acid Metabolism Ramifications” __________________________________ 52
C. Some Examples of Appropriate Diets that Limit,
Avoid and Cleanse Dietary Cholesterol and Related Residues ______________ 53
D. Global Warming Environmental and Food Production Benefits ____________ 54
iii.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great
Pathophysiological Ramifications” of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA, Protein and Fat in the Aboriginal Vegan Genome Human Body”

CONTENTS
SECTION PAGE

XII. Projection of American Health Care Expenditure and Leading Causes of


Death Reductions in the World’s Costliest Health Care System ________________________________ 55

A. Sub-Group D: Dietary Cholesterol Avoidance Life Style Change _____________ 55


B. Health Care Costs & Causes of Death Projected Reductions ________________ 56
C. Vegan/Vegetarian and Body Detoxification Life Style Incentives _____________ 57

XIII. Ideal Need to Convene 2011 US Congressional Health National Security Investigations ___________ 58

XIV. Conclusion __________________________________________________________________________ 60

XV. Dedication and Certification ___________________________________________________________ 62

XVI. Bibliography __________________________________________________________________________ 64

TABLES

I. Leading Causes of Death in USA in 1996, 2000 and 2006:: The Esoteric Top Fifteen Killers (TFK) __ 7

II. Fecal Endogenous And Dietary Cholesterol, Coprostanol, Primary And Secondary Bile
Acids And Salts In Human Omnivores, Vegetarians And Vegans (Herbivores)
A. Aries ___________________________________________________________________________ 15-1
B. van Faassen (Tables 1, 2, 3, 5)______________________________________________________ 15-2

III. Inventory of Mutagenic, Carcinogenic, Atherogenic and Toxogenic Agents Etiologically


Implicated in Colorectal Cancer, Heart Disease and other Chronic Diseases and Syndromes _____ 17

IV. Thirteen of the Top Fifteen Killing (TFK) Diseases Identified as Dietary Cholesterol and
Related Diseases and Syndromes (DCRDS): Comprehensive Results of the DCRDS
Systems Analysis Body Flow Chart _____________________________________________________ 19

Jones Table 2: Endogenous Cholesterol FSR’s & Daily Mevalonic Acid Excretion of
Subjects Consuming Diets Differing in Dietary Cholesterol _________________________________ 29

V. Inventory of Toxic Bile Acids and Neutral Steroids Exposed to Fetuses, Neonatals and Infants ____ 46

Ellis Table 3: Annual Yield of Nutrients and per 100 man-hours of labor __________________________ 55

VI. DCRDS Prevention Education and Death Cause Averted and Money Save Annual Projections ____ 57

APPENDIXES

A-1. The Aboriginal Diet of Humans (Homo Sapiens)

I. Ancient African, Eastern and Middle Eastern Cultures and Civilizations: “Golden Age”
II. Ancient European and North Asian Culture and Civilizations: “Mammal Cannibalism”
III. Origin of the Vegetarian Diets of Africa and Asia: “Accommodation”
IV. Mitochondrial Eve, the Evolution of Homo Sapiens and Great Law of Vegan Human Diet

A-2. The Aboriginal Christians were Vegans

I. Writings on the Jesus Christ Disciples as Vegans


II. Early Christian Clergy and Saints Testimony
III. Bible References: Vegan and Vegetarianism: Original Ideal and Ultimate Hope
IV. Bible References: God Cares About Animals and Wants Us to Care About Animals
V. Bible References: Animal Sacrifices Are Rejected by God
VI. Past and Present Notable Philosophers, Scientists and Authors Testimony

A-3. The Ramifications of the Invention of Hunting, Animal Husbandry Agriculture and the Novel and
Experimental Carnivore and Omnivore Diets
A. Preface : The Origin of Animal Meat Eating Spawns The White Race and The Myth of White Supremacy
B. Introduction: The Aboriginal Human Condition of Diet, Habitat and Occupation
C. Deleterious Ramifications
I.) Decrease in Atmospheric CO2 and Beginning of Present Quaternary Ice Age [circa 3,000,000 BC to present]
Table I. Inventory Table of Ancient Hominids: Plant Food Gatherers, Dead Animal Meat
Scavengers and Alive Animal Hunters
Table II. Inventory Table of Anthropogenic Extinct European and Asian Mega-Fauna
A.) World Off Axis
B.) World Flips Upside Down
II.) Loss of Humus Top Soil Desertification and Deforestation
III.) Loss of Black Skin Color to Brown and Yellow Color By Those European and Asian Peoples
Following the Novel Omnivore Diet
IV.) Loss of Brown Skin Color to White Skin Color by those following the Demonic Carnivore Diet
A.) Neanderthal Mutation of Pale White Skin [circa 200,000 BC.]
B.) European Homo Sapiens Sapiens Mutation From Brown to White Skin [circa 18,000 BC]
iv.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great
Pathophysiological Ramifications” of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA, Protein and Fat in the Aboriginal Vegan Genome Human Body”

CONTENTS

APPENDIXES (Continued)

B. Bruno Meessen, PhD. et al, editorial “Iatrogenic Poverty” in Trop Med and Inter Hlth J, 8 (7) pp. 581- 4, 2003

C. Press Release and the Science Magazine, May 17, 2002 article by Makoto Makishima, PhD, et al,
“Vitamin D Receptor as an Intestinal Bile Acid Sensor.”

D. Izrael Hieger, D. Sc., Research Articles and Book Extracts on Dietary Cholesterol as Carcinogen, 1930-62

E. Dean Ornish, MD. editorial “Mostly Plants” in Journal of American Cardiology, May, 2009

F. George W. Singleton, HD. Holistic Reversal of Alzheimer’s Disease and Parkington’s Disease Dementia

G. Jay M. Hoffman, PhD’s Hunza: 15 Secrets of World's Healthiest and Oldest Living People, 1985 synopsis

H-1. George W. Singleton, HD. “Avoid the White Foods” extract from Original Prevention of Sickness:
General Nutrition Instructions (OPS), 1997, rev. 2005

H-2. George W. Singleton, HD. “The 12 Causes and Prevention of Cancer” extract from OPS, 1997, rev. 2005

I-1. Amnesty International USA Citation of American Genocidal Maternal and Infant Mortality Rates, 3/2010

I-2. Global Maternal and Infant Death Rates Decrease while American Rates Genocidal Increase, 4/2010

I-3. Glantz, Anna, et al, article “Intrahepatic Cholestasis in Pregnancy: Relationships Between Bile Acid
Levels and Fetal Complication Rates” in Hepatology J, V 40, No. 2, pp 467-74, 2004

J. D. Gary Young, ND., “pH Balance: The Importance of Alkalinity to Health” extract from People’s Desk
Reference to Essential Oils, First Edition, Pages 156-58, 1999

FLOW CHARTS

#1. George W. Singleton, HD. General Human Systems Theory (GHST) Poverty Systems Analysis—Detailed
2005

#2. George W. Singleton, HD. Dietary Cholesterol & Related Diseases (DCRDS) Human Body Systems Analysis
2011
0.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great
Pathophysiological Ramifications” of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA, Protein and Fat in the Aboriginal Vegan Genome Human Body”

PREFACE

NOTE: This 7/06/2010 cover letter to the Green Paper and Appendixes A-1, A-2 and E fax sent to the US
Department of State Secretary Hillary Rodman Clinton resulted on 9/20/2010 with the American
Ex-President Bill Clinton announcing during a CNN Wolf Blitzer’s Interview that he had made the
vegan lifestyle change and loss 24 pounds and his cardiovascular heart condition requiring
open heart surgery in 2004 was completely cleared up. We give thanks to the Most High God
Annu for Its science of truth.

US Secretary of State Hillary Rodman Clinton 7/06/2010


US Department of State
Washington, DC.
202-647-0244 fax

Your Honor Secretary of State Hillary Rodman Clinton:

Please find attached the Green Paper: Resolution of the American Health
National Security Issue Omission: The Great Ramifications of Dietary
Cholesterol and Bile Acid Metabolism.

It is vital that you and your executive staff review this document immediately and
develop the appropriate responses because of its following implications and
applications:

A. the implication that America is promulgating an unhealthy lifestyle that


supports Iatrogenic death and poverty to the other industrial countries
especially its allies;

B. the implication that America is promulgating an unhealthy lifestyle that


supports Iatrogenic death and poverty to the developing countries
especially where significant development investments have been made;

C. the implication that America's genocidal levels of maternal and infant


death and morbidity could be ameliorated and improve its international
standing in these regards;

D. the implication that America will lose its international leadership if this
identified "health national security issue omission" is not properly
addressed from the deteriorated ability of the American youth to meet
military service standards and scientific research, educational and
employment opportunities; and

E. The application of various resolution options to address the identified


problem would strengthen America's ability to continue its international
leadership with a healthier people.

Finally, the cardiovascular heart problems of your husband President Bill


Clinton should be immediately reassessed knowing that Dr. Dean Ornish, MD.
has definitively developed and authenticated that this condition can be
reversed. His "Mostly Plants" editorial from the 2009 American Journal of
Cardiology is also attached for your review.

Yours in service,

George W. Singleton III, BA., HD., DD.


BRCA, Inc. President
State of the World Forum Member # 20827
2007 and 2009 European Union Humanitarian Grantee

PS. Green Paper cited Appendixes and Flow Charts not attached can be complementary
downloaded at http://www.theuniversityofgod.org/Page8.html.
1.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes:
“The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary
Cholesterol, Bile Acid, DNA, Protein in the Aboriginal Vegan Genotype Human Body”

I. Introduction

As the 2007 and 2009 European Union Humanitarian Grantee in America the objectives of the United
Nations’ Millennium Project of reducing extreme poverty within and outside America are my objectives.
Identifying the major cause of Iatrogenic Poverty and much of Economic Poverty as the suppressed
and largely unknown, unaddressed and preventable nutritionally related illnesses is my priority.

Consequently, it is my duty to point out humbly that the debate and documentation leading to the 2010
passed American Health Care System Reform Legislation (Legislation) including the nation's health
care system problem analysis, the projected costs and savings and the "100 Best Practices Research
Topics" were epistemologically corrupted as the cause(s) of the chronic diseases and syndromes
were not addressed. This is because it is a US "National Security (NS)" Issue and ideally and practically
now requires a US Executive Branch “NS” Forum to properly resolve by necessity and ideally behind
closed doors beyond special interest lobbyist tampering and mass media promulgation until desired.

My Resume is linked to http://www.theuniversityofgod.org/index.html as the reader needs to know


my academic and work background in the synthesis of rural health research methodology, poverty
abatement adjudication, policy development and demonstrations and the practice for 30 years of
nutritional herbology __the sickness treatment epistemological opposite to allopathic medicine __ to
assess the iconoclastic material presented herein.

II. Objective

It had been requested since September, 2009 that a US Senate Select Committee on Human
Nutrition and Human Needs, Chaired by the US Senate HELP Committee Chairman Tom Harkin (D,
IA.) and/or a US House of Representative Hearing; e.g. the House Ways and Means Committee,
now Chaired by Congressman Sander “Sandy” Levin ( D, MI. 12 th District) be convened by necessity
initially behind closed doors. The objective would be to verify the "Health National Security Issue
Omission" identified and detailed herein so that a documented quantified savings in the Nation’s
healthcare expenditures from subsequent properly directed sickness prevention education and practice
incentives can be achieved. This would in turn lead to bipartisan support and implementation of
Health Care Reform.

However, since the previously requested convening of a 2010-2011 US Select Committee on Human
Nutrition and Human Needs and/or US House of Representative/Ways and Means Committee
Hearing is politically impossible now that the National Republican Party has made the US Congress
passage of the Health Care Reform Bill a November, 2010 national election issue and repeal target; this
Purple Paper now proposes that the White House Office of Health Care Reform hold a Forum on
American Maternal and Infant Mortality Etiology and Possible Solutions possibly on-line moderated
ideally by Dean Ornish, MD., Director, Preventive Medicine Research Institute to address the
complicated and controversial etiological roles of Dietary Cholesterol and Bile Acid Metabolism.

It is felt that the ignorance of this "Health National Security Issue Omission" by the opponents of the
Health Care Reform Legislation can only be addressed effectively by its exposure because the
“shame of ignorance” will disarm this as a November, 2012 election issue again by necessity held
initially behind closed doors with the same objective. Is it possible for the US Congress to do the
unexpected and have a bipartisan and overwhelming majority of both parties implementing an
American Health Care System Reform Legislation that reflects this "Health National Security
Issue Omission" based on an appropriately self-funding design and a "sickness prevention health
education and practice incentives” implementation enrolling all Americans? Yes, if this request for
such a White House Office of Health Care Reform sponsored Forum on American Maternal and
Infant Mortality Etiology and Possible is met! The US Supreme Court Justices need to read this!

III. The American Health National Security (NS) Omission of “The Great
Pathophysiological Ramifications of Dietary Cholesterol and Bile Acid Metabolism"

American clinical allopathic Medical Doctors (MD’s) by definition are taught and use clinically an allopathic
health care paradigm. In sickness treatment epistemological terms "allopathic" means a health care
paradigm which targets primarily symptoms of a disease or syndrome in order to produce an opposite
effect. The allopathic clinical MD's standard laboratory references include Todd, Stanford and Davidson’s
Clinical Diagnostic and Management by Laboratory Methods, 2 Volumes; and page 317 of its 1979
edition sums up this "National Security Health Issue Omission" best:

"The pathophysiological ramifications of bile acid metabolism are great and


beyond the scope of this chapter (or any chapter in the 2 Volume edition)."
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” ___________________________________ p 2

As the Todd, Stanford and Davidson, Clinical Diagnostic and Management by Laboratory Methods
represents the standard allopathic clinical physician paradigm medical lab reference; it is clear that most
medical scientists, practicing physicians and other health care providers are unaware of this most
complicated and corrupted medical science subject area. More succinctly for the vast majority of
America's allopathic medical doctors, osteopathic physicians, dentists, nurses, dieticians, physical
therapists and chiropractors the "metabolism of the primary bile acids," the “metabolism of their
precursor Dietary Cholesterol” and the “enteric bacterial degradation toxemia products of the
misnomer ’secondary bile acids’ and the ‘tertiary bile acids’” and "their subsequent great
pathophysiological ramifications” are left out of their research and clinical education and training.

Instead American clinical MD.'s and other health practitioners are left with the symptomatic use of high
tech health diagnostic electronics, prescription drugs, surgery including the transplant of dysfunctional
organs, nuclear radiation and other allopathic medical procedures to address the proliferation of
chronic diseases and syndromes. Because Dietary Cholesterol is involved in their independent risk
factors they are called herein the Dietary Cholesterol and Related Diseases and Syndromes
(DCRDS) that have gripped America in the last 30 years.

In other words, the chronic diseases and syndromes including the latest member of “Metabolic
Syndrome” detailed below are "the great pathophysiological ramifications of dietary cholesterol
and bile acid metabolism" which are herein called the Dietary Cholesterol and Related Diseases
and Syndromes (DCRDS). This Health National Security Issue has been suppressed for over 70
years from public knowledge and the Legislative debate by the allopathic physician lead medical
industry and the Special Interest pharmaceutical, animal meat, fish, dairy and restaurant industries.

Note: The "politically correct" stance that those who know about the 70 year suppression of the "great
pathophysiological ramifications of dietary cholesterol and bile acid metabolism" and are trying to
ameliorate the health care crisis it has spawned by citing its National Security damage and danger
to the American body politic are enemies of America is not true. Such critics are not attacking the
founding values of the American society and economy but are opposed to the Special Interest
industry profiteers blood sucking the American people.

A. The "Root Problems" of the American Health Care System

The "root problems" of America's health care system go beyond private verses public health
care insurance and the perennially increasing per capita cost of the health care industry that
dominates the public debate. These "root problems" are not public debate topics as they have
been made ad hoc taboo and suppressed by Special Interest groups into National Security
ones that are not to be talked about in the mass media.

In the last 70 years the failure of the American allopathic medical research institutions and medical
schools to conduct research, teach its students and communicate to the public the knowledge about "the
great pathophysiological ramifications of dietary cholesterol and bile acids metabolism" are the
key etiological elements in the "Dietary Cholesterol and Related Diseases and Syndromes (DCRDS)"
has lead to a deteriorated health care status in America with the following "root problems:"

1.) The unbalanced allopathic medical epistemological foundation of the medical sciences,
the medical education and the health care industry which abuses human rights in regards
to legal cancer treatment options and so-called healthy "balanced meat diet” alternatives.

Note: a.) The now deceased Vegetarian Mrs. Coretta King wife of Reverend Martin Luther King had
to “illegally” go to Mexico to get the alternative cervix cancer treatment she desired.

Note: b.) The majority of the allopathic and osteopathic physicians of elderly patients including those
with cancer in most states still advise the best diet is a "balanced meat diet;" although all
credible in vitro, in vivo and objective observational/epidemiological research clearly shows
the aboriginal Vegan Diet and less restrictive Vegetarian Diet as superior in lower disease
risk factor incidences, lower death rates, lower infant and maternal mortality rates and
longer life spans than the Omnivorous Diet.

2.) The proliferation of chronic diseases and syndromes which are in reality DCRDS where
50% of those who die of a non-cancerous disease when autopsied are also found to have
had cancer __ the “cancer epidemic background noise” __ caused by the modern
American high fat and high protein Omnivores Diet.

3.) Failure of the allopathic MD lead health care industry to prevent and control the chronic
diseases and syndromes including the most recent “Metabolic Syndrome” attributable to
the ingestion of Dietary Cholesterol and related Animal Protein and Animal Fat residues
whose causative relationship has been suppressed for over 70 years and continues to be so.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” _____________________________________ p 3

Of notable exception is the allopathic medical specialty of cardiology including the leadership
of Dr. William C. Roberts, M.D., editor of The American Journal of Cardiology who believes:

"When we kill the animals to eat them, they end up killing us because their flesh,
which contains cholesterol and saturated fat, was never intended for human beings."

As part of this notable exception is cardiologist Dr. Dean Ornish, MD. whose Reversal Diet
allows only 5 mg of cholesterol/day has been documented [Ornish, D., Scherwitz, L. W., Billings,
J. H.,Brown, S. E., Gould, K. L., Merritt, T. A. et al, “Intensive lifestyle changes for reversal of
coronary heart disease,” JAMA, 1998, 280: 2001- 2007] to be an authentic therapeutic diet
capable of reversing the #1 killer of Americans cardiovascular disease. Dr. Ornish’s Preventative
Diets are authentic cardiovascular disease preventive diets. He attributes the foundation basis of his
diets to his religious Hindu Hatha Yoga Master Swami Satchidananda. Please read Dr. Ornish’s
“state of the art” editorial “Mostly Plants” in the May, 2009 American Journal of Cardiology
included herein as Attachment E.

4.) Treating the symptom of high serum cholesterol levels caused by Dietary Cholesterol with expensive
and potentially harmful prescription drugs that suppress “bad” (LDL) cholesterol and increase
“good” (HDL) cholesterol objectively evaluated by sickness treatment epistemology is not the
best efficient and effective treatment compared to the aboriginal sickness prevention approach of
decreased eating of Dietary Cholesterol foods with the Vegetarian Diet or better abstaining from
such “pseudo” foods containing slow poisons with the Vegan Diet.

Predictably this issue is not even included in the 2009 federally mandated Institute of Medicine’s
100 Initial Priority Topics for Comparative Effectiveness Research of the “best practice”
questions as expected since this issue is being suppressed by the special interest lobbies of the
meat, restaurant, pharmaceutical and health care industries. Again the notable exception is Dr.
Dean Ornish, MD., Director of the Preventive Medicine Research Institute whose “Statins and
the soul of medicine”, editorial in the American Journal of Cardiology, V. 89, pp. 1286-1290,
June, 2002 challenges this popular prescription drug therapy.

5.) The emergence of America's "actual" number 3 leading cause of death after heart diseases and the
cancers of Iatrogenic Disease (caused by physicians and their health care system) resulting
yearly on average 250,000 deaths and the driving force behind the perennially increasing and
seemingly excessive malpractice insurance premiums practicing physicians must pay to protect
themselves from legal torts (suits). [D 3]

6.) The unsustainability of the present American health care system being ineffective and inefficient
compared with other industrialized nations reflected in America having twice the per capita health
care costs in 2009 projected at $8,000/person compared to other industrialized countries and yet
producing a below average health status internationally with 41 countries with longer Life
Expectancies and 27 countries with lower Infant Mortality Rates: This is embarrassing as
many of these countries are “developing” countries.

From sickness treatment epistemology this "Health National Security Issue Omission" of
"the great pathophysiological ramifications of dietary cholesterol and bile acid metabolism" is
the root cause of the unrelenting annual escalation of America's health care costs, the unrelenting
failure to produce significant improvement in morbidity and mortality rates, the excessive malpractice
rates and the 47 million Americans without access to primary health care.

In summary, the health care industry Special Interests including allopathic and osteopathic physicians,
the medical research schools; pharmaceutical companies, insurance companies; the meat, dairy, fish and
restaurant industry have suppressed this “Health National Security Issue” for over 70 years.

B. General Statistics -- National

The American health care industry lead by the allopathic MD’s is obviously performing inefficiently and
ineffectively looking at international comparisons of health care cost/benefit ratios and health care status
general statistics. The following general statistics indicate a crisis in health care of National Security
significance in America incapacitating and killing hundreds of thousands annually that can be easily
prevented and would extend millions of lives, save billions of dollars and significantly increase the GNP:

1.) Per Capita US Health Care Expenditures officially was $6,714 in 2006, more than twice
the average of other advanced countries. It is projected to be over $8,000 in 2009.

Note: Again there is a relationship between this high expenditure rate and the high malpractice insurance
rates American physicians must pay to practice. It is believed the esoteric Iatrogenic Disease
factor to be presented below plays a significant role here.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” ___________________________________ p 4

2.) US Infant Mortality Rate (IMR) at 6.9% (per 1000 live births) as reported in 2008 by the US
Center for Disease Control and Prevention (CDC) places America 29th in industrialized
countries compared with Japan's IMR of 3.1% and 3 rd amongst industrialized nations. The
IMR amongst African Americans at 16.7% is genocidal! See related 3.) below and
Appendixes I-1 and I-2.

Note a: The CDC in its 2008 Annual Report on the nation's Infant Mortality Rates pointed to the lack of
progress in infant mortality prevention from 2000 to 2006__ a lack of progress in this vital health
index not seen since the 1960's. America could once boast about its IMR but has steadily lost its
health status advantage internationally the last 30 years since passage of the Civil Rights Bill.

Note b: This period from 2000 to 2006 coincides with: i.) the proliferation of the high fat and high protein
fast food restaurants in America; ii.) the unannounced substitution of the federally subsidized
production of the higher caloric high fructose corn syrup for the lower caloric sugar cane and
sugar beet sucrose as a sweetener by America's refined food industry; iii.) an attempt to corrupt
medical science further with federal research using statistical manipulation of death rates to give
overweight and obese individuals’ longer life spans than normal and underweight individuals; iv.)
the appearance of the “Metabolic Syndrome” [the cluster of cardiovascular and diabetic risk
factors including visceral (waist) obesity, high blood pressure, insulin resistance, elevated
triglycerides and low HDL cholesterol]; and v.) the manifestation of the Metabolic Syndrome as
a major dysfunction of the people.

Note c: In a disturbing finding the infant merconum (first bowel movement after birth) as well as
neonatal newly born infant bile and infant blood contains high amounts of 22-Hydroxy
Cholesterol, C-24 mono-hydroxy bile acids called 3-beta-hydroxy cholenoic acid and
Lithocholic acid which are dangerous co-mutagenic, co-carcinogenic, atherogenic and
toxogenic linked to liver cholestasis (gall stone blockage of the gall bladder) and the
Oxysterols (24, 25 and 27 Hydroxycholesterols). In particular Premature babies are
associated with the at risk of high concentration of C-24 mono-hydroxy bile acids and high
Dietary Cholesterol maternal diets. [F14]

Esoterically as documented below and in Appendix A-1 because the human genome is encoded as a
herbivore/vegan genetically, the human liver of the pre-natal, neonatal and infant processes any
Dietary Cholesterol from the Mother’s shared blood system or amniotic fluid as a “slow poison”
through a “Third Bile Acid Metabolic Pathway” producing a unique mix of bile acids that persists from
conception but is slowly transformed after birth by the development of intestinal flora until about 4 years
of age when the adult pattern of cholesterol and bile acid metabolism dominates.

3.) US Maternal Mortality Rate (MMR) at 13.3% (per 100,000 live births) as reported in 2006 by
the UN World Health Organization up from 7% in 1996 places America 41st in industrialized
countries with Japan's MMR of 7.3% and 3 rd amongst industrialized nations. The MMR
amongst African Americans at 36.5% is genocidal! The last 10 years has seen a nearly
100% increase.

4.) As of 2006 America ranked 42 nd in Life Expectancy (LE) with 41 countries with longer LE’s
than the US's 77.7 years with Japan's 81.5 years the leader amongst industrialized nations.

5.) Amongst those who die in America and their bodies undergo autopsies it is found on average
that in 50% of the major non-cancer causes of death in America the deceased also suffered from
a simultaneous incidence of cancer. Table One further details this.

Note: This "background noise" of Cancer can easily be discerned and understood from a study
of the DCRDS Systems Analysis Body Flow Chart to be presented below in Section IV.

6.) Iatrogenic Disease (Doctor & health care Industry caused illness) is the "actual" #3 killer of
Americans after the #1 killer of Heart Diseases and #2 killer the Cancers with an underestimated
250,000 deaths annually. Table One further details this. [D3]

7.) There were an estimated 200,000 bankruptcies in America in 2008 due to Iatrogenic Poverty;
i.e. from health care related bills as well as morbidity suffering from DCRDS.

8.) Iatrogenic Poverty Deaths is estimated at 45,000 a year amongst uninsured adults]. [D15]

9.) The sudden appearance over the last 30 years of Metabolic Syndrome (Met S.) affecting over
20% of Americans can involve simultaneously 9 risk factors for overweight and obesity,
diabetes mellitus Type II, hypertension, and cardiovascular heart disease.

Etiologically suspect are the coinciding increased Dietary Cholesterol containing modern American
high animal protein and fat fast food diet, and the extensive use of blood cholesterol lowering
prescription drugs most notably the “statins” which decrease the natural production of Endogenous
Cholesterol and suppresses the immune system. [D 10]
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” ___________________________________ p 5

Note: The 9 risk factors of Metabolic Syndrome cited above are:

a.) increased waist circumference (over weight and obesity),

b.) elevated blood triglycerides,

c.) low blood HDL cholesterol,

d.) high blood LDL cholesterol,

e.) high blood uric acid,

f.) high blood pressure,

g.) fasting blood glucose,

h.) increased blood coagulation,

i.) in women high androgen levels, and

j.) in men high estrogen levels.

C. Esoteric Existence of Iatrogenic Disease & Iatrogenic Poverty Morbidity and Mortality

In 1975 the Austrian philosopher and Roman Catholic Priest Ivan Illich's iconoclastic and best selling
book entitled Medical Nemesis was released and shocked the American public with the esoteric
concept fully statistically documented of "Iatrogenic Disease" caused by the allopathic health
care industry of America.

Dr. Barbara Starfield, MD, PhD is an internationally recognized MD. and Public Health PhD. teaching
at the Johns Hopkins School of Hygiene and Public Health in Baltimore, MD. She has further
quantified what Ivan Illich warned of over two decades earlier as to the dangers of "Iatrogenic
Disease." Dr. Starfield courageously documented in her July 26, 2000 Journal of the American
Medical Association (JAMA) article "Is US Health Really the best in the world?" that allopathic
MD caused Iatrogenic Disease (MD's and their health care industry caused deaths) resulted in
250,000 deaths and was the "actual" number 3 killer of Americans behind #1 Heart Diseases
and #2 the Cancers in 2000 as follows:

106,000 __ non-error, negative effects of drugs


80,000 __ hospital infections
45,000 __ other hospital error
12,000 __ unnecessary surgery
7,000 __ hospital medication error
________

Total Iatrogenic Disease Deaths 250,000

It is contended that nothing has changed for the better in the American health care system since 2000
and that Iatrogenic Disease remains as the "actual" number #3 killer in America in 2006 up to the
present time in 2010 with an average 250,000 deaths annually.

The concept of "Iatrogenic Poverty" was first used in an editorial of that title by Bruno Meessen, et
al, Tropical Medicine and International Health, 8 (7) 581- 4, July, 2003 included herein as
Appendix B. Iatrogenic Poverty encompasses health care bills driving the patient and family into
poverty financial failure including asset mortgaging, liquidation and bankruptcy. People of all classes
and in industrialized and developing countries as well are suffering the hardships from morbidity and
mortality particularly from the Iatrogenic Poverty of the DCRDS:

“Poverty and illness are intertwined. It is a well documented fact that poverty leads to ill-
health. In every society, morbidity and mortality are higher amongst the poor.”

The Dr. Andrew P. Wilper, MD., MPH, et al article “Health Insurance and Mortality in U.S. Adults”
published on line and printed in the American Journal of Public Health, Vol. 99, Issue 12,
December, 2009 determines that there are on average 45,000 deaths annually amongst uninsured
individuals and serious morbidity levels compared to insured individuals; i.e. Iatrogenic Poverty
Deaths. Using national health survey data from 1984-1994 data for 3 chronic diseases and
syndromes _ diabetes, hypertension and high cholesterol __ which our sickness treatment
epistemology classified as DCRDS ___ Dr. Wilper’s research team found:
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” ____________________________________ p 6

a.) 46% of the uninsured with diabetes never received a diagnosis for it compared to 23% of those insured;

b.) 52% of the uninsured with high Cholesterol never knew they had the condition compared to 30% of insured;

c.) 78% of the uninsured with elevated Cholesterol were not in control of it compared to 60% of the insured; and

d.) 58% of the uninsured with high blood pressure did not know it compared with 51% of the insured.

This study’s co-author Dr. Steffie Woolhandler, MD., Professor of Medicine at Harvard University and
a primary health care physician in Cambridge, Mass. astutely noted:

“Historically, every other developed nation has achieved universal health care through
some form of nonprofit national health insurance. Our failure to do so means that all
Americans pay higher health care costs, and 45,000 pay with their lives”.

This study declares “the uninsured, working-age Americans have a 40 percent higher risk of death
than their privately insured counterparts, up from a 25 percent excess death rate found in 1993”.

D. The "Background Noise" of the Cancer Epidemic

As presented above in Section III. B. 4 amongst those who annually die in America and their bodies
undergo autopsies it is found on average that in 50% of the non-cancer leading causes of death in
America the deceased also suffered from a simultaneous incidence of cancer that did not kill them.
Esoterically, this "background noise" of Cancer can easily be discerned as the allopathic health care
industry's institutional control of the statistics of the Cancer epidemic with its "root-cause" intermixed in
the 70 year suppression of "the great pathophysiological ramifications of dietary cholesterol and
bile acid metabolism.”

This can be clearly seen and understood from a study of the DCRDS Systems Analysis Body Flow
Chart to be presented below in Section IV. By extrapolating this statistical "non-killing cancer
incidence" in those who die annually from one of the other TFK's, we can get a better esoteric full
picture of the "Cancer background noise" ___ the “hidden part of the iceberg" of the systemic
cancer epidemic that has gripped America as follows:

1996 ___ there were 539,323 Americans who died of Cancer.


___ there were 690,000 Americans who died of a TFK
other than cancer but also had Cancer.

2000 ___ there were 552,988 Americans who died of Cancer.


___ there were 701,036 Americans who died of a TFK
other than cancer but also had Cancer.

2006 ___ there were 559,801 Americans who died of Cancer.


___ there were 682,373 Americans who died of a TFK
other than cancer but also had Cancer.

E. The Top Fifteen Killers (TFK) of Americans in 1996, 2000 and 2006

It is hereby declared that the reality of the Top Fifteen Killing (TFK) Diseases__ defined herein as
taking the Leading Causes of Death in America and adding the esoteric existence of Iatrogenic
Disease mortality and Iatrogenic Poverty mortality __ reflect and encompass the effects of the over
70 year suppression of "the great pathophysiological ramifications of dietary cholesterol and bile
acid metabolism" by the medical research, medical education and health care institutions of the
allopathic medical health care complex in America.

TABLE ONE: Leading Causes of Death in USA in 1996, 2000 and 2006: Top Fifteen Killers(TFK’s)
of Americans which is attached compares the Top Fifteen Killing Diseases in America (TFK's) in
1996, 2000 and in 2006. TFK's are defined as taking the Leading Causes of Death in America and
adding estimated levels of the esoteric existence of Iatrogenic Disease and Iatrogenic Poverty
mortalities.

Please note there exists in Table One a big difference in the number of deaths between the #2 TFK of
Cancer and the #3 TFK of Stroke. This is theorized as a statistical manifestation of the suppression of
the “great ramifications of dietary cholesterol and bile acid metabolism” as will become more and
more clear within the Purple Seal.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” ___________________________________ p 7

TABLE ONE::
Comparison of Leading Causes of Death in USA in 1996, 2000 and 2006:: Generation of the Esoteric Top Fifteen
Killers (TFK) of Americans including the Esoteric “Background Noise” of the Cancer Epidemic, Iatrogenic
Disease and Iatrogenic Poverty Deaths. TFK's are defined as taking the Leading Causes of Death in America and
adding estimated levels of the esoteric existence of Iatrogenic Disease and Iatrogenic Poverty mortalities.

Common # Deaths Death Rate Common # Deaths Death Rate Common # Deaths Death Rate
Name in 1996 in 1996 Name in 2000 in 2000 Name in 2006 in 2006
(% of Total per 200,000 (% of Total per 200,000 (% of Total) per 200,000
2,314,690) 2,374,860) 2,426,517)
________________________________________________________________________________________________________________

1.) Heart 733,757 278.7 1.) Heart 710,208 258.2 1.) Heart 631,250 200.2
Diseases (31.7%) Disease (29.9%) Diseases (26.3%)

2.) Cancers 539,323 203.4 2.) Cancers 552,988 200.9 2.) Cancers 559,801 180.7
(23.3%) (23.3%) (23.3%)
+ 2.’) TFK Deaths 690,071 262.1 2.’) TFK Deaths 701,036 254.9 2.) TFK Deaths 682,373 216.4
with Cancer (29.8%) with Cancer (29.5%) with Cancer (28.1%)

* 3.') Iatrogenic 200,000 76.0 3.’) Iatrogenic 250,000 91.0 3.) Iatrogenic 250,000 80.3
Disease (8.6%) Disease (10.5%) Disease (10.3%)

3.) Stroke 159,714 60.3 3.) Stroke 167,535 60.9 3.) Stroke 136,976 43.6
(6.9%) (7.1%) ( 5.7%)

4.) Asthma/ 106,476 40.0 4.) Asthma/ 121,971 44.3 4.) Asthma/ 124,549 40.5
Emphysema/ (4.6%) Emphysema/ (5.1%) Emphysema/ (5.2%)
Bronchitis Bronchitis Bronchitis

5.) Accidents 94,902 35.8 5.) Accidents 96,934 35.6 5.) Accidents 120,395 39.8
(4.1%) (4.1%) (5.0%)

6.) Influenza 83,329 31.6 6.) Diabetes 69,021 25.2 6.) Diabetes 72,922 23.3
& Pneumonia (3.6%) (2.9%) (3.0%)

7.) Diabetes 64,497 23.3 7.) Influenza 65,021 23.7 7.) Alzheimer's 72,482 22.6
(2.7%) and (2.7%) (3.0%)
Pneumonia

**8.’) Iatrogenic 20,000 8.’) Iatrogenic 30,000 8.’) Iatrogenic 40,000


Poverty Poverty Poverty
Syndrome Syndrome Syndrome

8.) HIV 30,091 11.1 8.) Alzheimer's 49,566 18.0 8.) Influenza 56,060 17.8
(1.3%) (2.1%) & Pneumonia (2.3%)

9.) Suicide 30,091 10.8 9.) Kidney 37,087 13.5 9.) Kidney 45.182 14.5
(1.3%) Diseases (1.6%) Diseases (1.9%)

10.) Liver 25,462 9.5 10.) Septicemia 30,949 11.3 10.) Septicemia 33,965 11.0
Diseases (1.1% ) (1.3%) (1.4%)

11.) KIdney 23,147 9.2 11.) Suicide 29,546 10.8 11.) Suicide 33,292 10.9
Diseases (1.0%) (1.2%) (1.4%)

12.) Septicemia 20,832 8.1 12.) LIver 18,072 9.6 12.) Liver 27,546 8.8
(0.9%) Diseases (1.1%) Diseases (1.1%)

13.) Alzheimer's 20,832 8.1 13.) Hypertension 18,072 6.6 13.) Hypertension 23,855 7.5
(0.9%) (0.8%) (1.0%)

14.) Homicide 20,832 7.9 14.) Pneumonitis 16,626 6.1 14.) Parkinson's 19,565 6.3
(0.9%) (0.8%) (0.9%)
15.) Arterio-
sclerosis 20,832 6.3 15.) Homicide 16,386 6.1 15.) Homicide 18,218 6..2
(0.7%) (0.8%) (0.8%
__________ _________ _________
^ TFK TOTALS: 1,969,488 1,999,992 1,976,058
(85.1%) (84.2%) (81.4)
** DCRDS TOTALS: 2,119,465 2,204,060 2,174,548
(84,3%) (84.0%) (81,2%)
NOTES:
+ This is the "Cancer Background Noise" of the estimated 50% of those who died of a Top Fifteen Killer (TFK)
other than Cancer
who upon autopsy were found to have also had Cancer. Accidents, Suicide and Homicide not included. Please see text.
* Dr. Barbara Starfield, MD., PhD. calculations for Iatrogenic Disease Deaths in July 26, 2000 Journal of the American Medical
Association (JAMA) article "Is US Health Really the best in the world?" were used to extrapolate its levels for 1996 and 2006.
** Dr. Andrew P. Wilper, M.D., M.P.H., et al calculations for Iatrogenic Poverty Deaths in American Journal of Public
Health (AJPH)_ online and print edition Vol. 99, Issue 12, December, 2009 article “Health Insurance and Mortality in
U.S. Adults” was used to extrapolate its levels for 1996 and 2006.
^ The TFK TOTAL does not include Accident and Homicide deaths but includes esoteric "Cancer Background Noise"
deaths, Iatrogenic Disease and Iatrogenic Poverty death estimates. Please see text.
^^ DCRDS Total refers to the Dietary Cholesterol and Related Diseases and Syndromes (DCRDS).
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” ____________________________________ p 8

IV. Etiology of Animal/Dietary Cholesterol and Related Diseases and Syndromes (DCRDS)

A. Animal/Dietary Cholesterol is not a Human Dietary Requirement

Magill’s Medical Guide, [Salem Press, Inc.] 2005 3 rd revised edition Volume I, pages 492-493
edited by Tracy Irons-Georges declares with emphasis added:

“The body can meet its needs for cholesterol through synthesis; there is no dietary requirement.
Cholesterol deficiency does not arise in humans even on a purely vegetarian [cholesterol free
(herbivore/vegan)] diet. …. The liver is the most important site for cholesterol synthesis within
the body …. Mammalian cells have the capacity to synthesize their own cholesterol.”

Yes, there is no scientific basis nor other valid nutritional need for humans to ingest animal flesh.
Esoterically human animal flesh ingestion is done from superficially hidden and demonically
dominated metaphysical and cultural socio-political economic reasons. To do so is a violation of
“The Great Law” presented in the Bible Genesis 1: 29 as the aboriginal human nutritional directive
to follow the herbivore/vegan diet based on the aboriginal knowledge that the human genome is
herbivore/vegan. Ironically, as the human body treats an organ transplant as foreign and rejects it
so it does with Dietary Cholesterol; i.e. the “great ramification of dietary cholesterol and bile acid
metabolism” is the “Omnivore’s Dilemma” and a priori does not occur in herbivore/vegan diets.

B. Stereoisomer Specificity & Organic Steroid Chemistry of Cholesterol

steroid molecule numbering Natural- Cholesterol (5 cholesten 3-beta-ol)

Above left is the stereoisomer steroid chemistry numbering used for the steroid molecule of Cholesterol
for both the Human Endogenous Cholesterol and its isomer Animal Dietary Cholesterol needed to
comprehend the primary etiological role of Dietary Cholesterol in chronic diseases and syndromes.
By convention the molecule lies on the plane of the paper and positions 18, 19 and 29 show a “solid cone”
or beta-configuration as they lie above the plane of the paper while positions 28 and 30 show the
“striated cone” or alpha-configuration below the paper plane. Take note that the cholesterol molecule
is a steroid with a weak “polycyclic aromatic (PA)” structure with an unsaturated, double carbon bond at
the C5-6 positions of Ring B. A PA structure is characteristic of mutagens and carcinogens.

Above right are shown indicated as circles the cholesterol molecule’s 8 stereocenters giving it “2 to
the 8th power” or 256 possible isomers. Each specific individual of each animal species on earth which
makes cholesterol including that of the mammalian vertebrate species of humans (homo sapiens) makes
cholesterol molecule isomers that are unique to that specific animal species individual. Endogenous
Natural - Cholesterol and its isomers have the following organic chemistry stereoisomer specificity:

1.) IT CAN NOT BE SUBSTITUTED with molecules of a different human’s Endogenous Cholesterol; and

2.) NOR CAN IT BE SUBSTITUTED by the Dietary Cholesterol from butchered, cooked animal meat or
rennet based dairy products ______ WITHOUT a varied and holistic full body immune system response;
i.e. symptoms analogous to “transplanted organ/tissue rejection” with inflammatory blood and white
cell tissue markers and Animal Dietary Cholesterol antibodies as associated with the autoimmune
diseases of atherosclerosis, diabetes and Alzheimer’s disease with a dementia produced by placques
from mutagenic clone white blood cells secreting amyloidal muco- fibroid-protein dominate.

The Human molecule Natural (Endogenous) Cholesterol (Nat-Cholesterol, 5 cholesten 3-beta-ol):

Nat-Cholesterol
(Nat-Cholesterol)
[5 cholesten 3-beta-ol]

It is theorized herein that Human Endogenous Nat-Cholesterol has “isomer twins” in the
Animal/ Dietary Cholesterol of the mammalian beef, pig, lamb and goat meat and dairy products
as well chicken and other avarian, fresh and salt water pseudo” foods that Omnivores and dairy
product Vegetarians are consuming. They will cause a cholesterol antibody immune reaction.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” ____________________________________ p 9

The major isomers of human nat-Cholesterol are 1.) ent-Cholesterol; 2.) epi-Cholesterol;
3.) Lathosterol and 4.) 7-Dehydrocholesterol and they are described below:

1.) The Nat-Cholesterol “Mirror image” isomer called enantiomer- (or) ent-Cholesterol (5 cholesten
3-alpha-ol) of exact chemical composition and properties does possess the same cell membrane
component electro-magnetic display in reverse, the same physical properties and similar biological
and chemical reactions as does Natural (Endogenous) Cholesterol.

It is theorized that Ent-Cholesterol is a major isomer component of Animal/Dietary Cholesterol


acquired from mammalian beef, pig, lamb and goat meat and dairy products as well chicken and
other avarian, fresh and salt water pseudo” foods that Omnivores and dairy products Vegetarians
are consuming. It will cause a cholesterol antibody immune reaction.

Ent-Cholesterol
[5 cholesten 3-alpha-ol]

Note: In vivo tissue culture research indicates that ent-Cholesterol can support cell growth during the first
generation. However, cell death results in generation two reflecting that the necessary mitosis
proteins and enzymes being enatiomerselective need the nat-Cholesterol stereochemistry
configuration. [F. 36]

2.) The Nat-Cholesterol “epimer isomer” called Epicholesterol [5 cholesten 3-alpha-ol] although of
exact chemical composition and properties does not possess the same cell membrane component
electro-magnetic display, physical properties and biological and chemical reactions as does Natural
(Endogenous) Cholesterol.

It is theorized that Epicholesterol is a major isomer component of Animal/Dietary Cholesterol


acquired from mammalian meat and dairy products as well chicken and other avarian, aquatic animal
“pseudo foods” that Omnivores and dairy products Vegetarians are consuming. It will cause a
cholesterol antibody immune reaction.

Epicholesterol
(3 alpha- isomer) epimer
[5 cholesten 3-alpha-ol]

Note: In vivo tissue culture research indicates that epicholesterol can not support cell growth during
the first Generation leading to cell death results reflecting that the necessary cell membrane
generation involving non-enatiomerselective lipids need the nat-Cholesterol stereochemistry
configuration. [E. 15]

3.) The Nat-Cholesterol “generic isomer” called Lathosterol [5 cholesten 3-beta –ol] was discovered
in 1951 and is hard to separate from Nat-Cholesterol. It is considered a precursor (cholesterol
biosynthetic pathway intermediary) in and a marker of whole body synthesis of cholesterol.

It is theorized that Lathosterol is a major isomer component of Animal/Dietary Cholesterol acquired


from mammalian meat and dairy products as well chicken and other avarian, aquatic animal “pseudo
foods” that Omnivores and dairy products Vegetarians are consuming. It will cause a cholesterol
antibody immune reaction.

Lathosterol
Cholesterol Isomer
[5 alpha cholest-7-en 3-beta–ol]
[7-cholsten-3-beta-ol]
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” ___________________________________ p 10

4.) The Nat-Cholesterol “hormonal isomer” called 7-Dehydrocholesterol (Pro-Vitamin D3) is a


metabolite from cholesterol by the mammalian liver found in the serum and tissues of all mammals.
It is in the skin further metabolized by UVB light into Vitamin D3.

It is theorized that 7-Dehydrocholesterol is a major isomer component of Animal/Dietary


Cholesterol acquired from mammalian meat and dairy products as well chicken and other avarian,
aquatic animal “pseudo foods” that Omnivores and dairy products Vegetarians are consuming. It
will cause a cholesterol antibody immune reaction.

7-Dehydrocholesterol
(Pro-Vitamin D3)
[3beta-Cholesta-5,7-dien-3-ol]
[cholesta-5,7-dien-3-beta-ol]

It is important to note herein that a distinction is made in the cancer etiological language used between
mutagenic agents and carcinogenic agents be they inorganic chemical, organic (hydrocarbon)
chemical, biochemical, viral, electromagnetic or radioactive in nature:

a.) “mutagenic agents” cause DNA chromosomal nucleotide base changes to a specific cell
producing various phenotype abnormalities including in the case of cancer neoplasm
appearance and behavior that is passed on in that cell’s gene meiosis and mitosis; and

b.) “carcinogenic agents” promote the growth, survival and spread of neoplasm cancer cells.

Note : 1.) That the polycyclic aromatic biochemical steroid Cholesterol and its Bile Acid
derivatives are suspect as and can be both mutagenic and/or carcinogenic agents.

2.) That the polycyclic aromatic hydrocarbon chemicals like benzpyrene can be both
or singularly mutagenic and/or carcinogenic agents.

C. Colorectal Cancer Cause Identified & Connected to America’s High Fat Diet

In 1974 the ground breaking article was published by T. Narisawa et al entitled “Promoting effect of bile
acids on colon carcinogenesis after intrarectal instillation of N-methyl-N'-nitro-N-nitrosoguanidine
in rats” in the Journal of the National Cancer Institute, V. 53, pp. 1093 funded by the Great Britain
National Institute of Health first connecting colorectal cancer to bile acid metabolism. Specifically,
this article was the first to document that the so-called secondary bile acid Lithocholic Acid (LCA)
promoted the known chemical mutagenic and carcinogenic agent called N-methyl-N'-nitro-N-
nitrosoguanidine. Thus by our definition and the authors T. Narisawa et al so cited LCA is a co-
carcinogenic agent. Note that this article was obviously missed by the definitive milestone findings of
the US Senate Select Committee on Human Nutrition and Human Needs convened by US Senator
George McGovern released 2 years earlier by the US. Government Printing Office (GPO) in 1972.

Fortunately, 25 years latter in 1999 Japanese medical scientists lead by Makoto Makishima, PhD.
Professor, Department of Biochemistry, Nihon University School of Medicine, Tokyo, Japan observed the
comparative epidemiological data of red meat ingestion between Japan and America and the higher
incidence of colorectal cancer in the latter. He was funded to do research at the University of Texas
Southwestern Medical Center in another area of cholesterol and bile acid metabolism, that of Vitamin
D3 which is made in the human body from a precursor from Endogenous Cholesterol. Makishima’s
work was reported in an article in the Science Magazine, May 17, 2002 issue entitled "Vitamin D
Receptor as an Intestinal Bile Acid Sensor."

Dr. Makoto Makishima's own research confirmed that Dietary Cholesterol was catabolized in the human
liver into the so-called primary bile acid Chenodeoxycholic acid (CDCA), and that CDCA was in turn
transformed by anaerobic pathogenic bacteria in the human colon into the so-called secondary bile
acid Lithocholic Acid (LCA). LCA's role in causing the number 2 death causing cancer site of
colorectal cancer in America cannot be denied. The University of Texas Southwestern Medical
Center Press Release on Makishima's article in the Science Magazine cited above and the article itself
are attached as Appendix C.

Consequently, since 1974 the secondary bile acid LCA has been identified as the most powerful
biochemical carcinogenic agent known to science. Although it is not mutagenic it is toxic to the liver
whose prime directives include detoxification of poisons; it is toxic to the pancreas, spleen, heart, lungs
and kidneys; and additionally holistically promotes the growth and spread of already existing cancer cells
(neoplasms) and thus is carcinogenic.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 11

With both humans and most domesticated animals being mammals, animal meat is similar to human
flesh. For a human who genetically is like the mouse a herbivore [not like the rat and pig who are
genetically omnivores] the biggest problems of eating mammalian animal meat are the ramifications
to the human body of "mammal cannibalism." The herbivore human body can not fully digest the
"pseudo" food of animal meat which is composed of but not limited to the following animal biochemical
elements that are human diet unnatural and antigenic in the body:

a.) muscle tissue made up of cell membranes of Animal/Dietary Cholesterol, fatty acids, the 20 protein
amino acids especially cystein, methionine, glycine and tryptophane and with myolin and actin fiber
proteins which allow it to contract and the neuroproteins of DNA and RNA of cellular nuclear encased
genetic material;

b.) muscle nerve tissues which is made up of cell membranes of Dietary Cholesterol, fatty acids, the 20
protein phospholipids and the neuroproteins of DNA and RNA of the nerve cell's nuclear encased
genetic material;

c.) blood vascular tissue made up of cell membranes of Dietary Cholesterol, fatty acids, the 20 protein
amino acids especially cystein, methionine and glycine and tryptophane; the neuroproteins of
DNA and RNA of the nerve cell's nuclear encased genetic material and red and white blood cells and
their components; and

d.) connective tissue and intracellular mucopolysaccharrides.

The Medical Sciences since Professor Makoto Makishima's 2002 Science Magazine article have
continued to try and avoid implicating Animal/Dietary Cholesterol in the etiology of colorectal cancer.
Predictably they have and are trying to apply therapeutic pharmacological techniques to control the
underlying chronic enteric toxemic infection producing the Secondary Bile Acids and their further
bacterial degradation to Tertiary Bile Acids. Especially of concern here are the anaerobic pathogenic
clostridium bacteria which are capable of Nuclear Dehydrogenation (HDH) of the” A-ring” of the
steroid bile acid structure to a “4-ene-3 one configuration.” As polycyclic aromatic hydrocarbons
this makes these transient Tertiary Bile Acids suspect as highly mutagenic and carcinogenic.

The quandary faced by colon cancer researchers in this cited environment of decades of special
interest medical institutional and industrial cancer etiological knowledge suppression of colorectal
cancer’s cause is epitomized by Bandaru S. Reddy, DVM, PhD. and Ernest L. Wynder, MD. In their
1977 astute article “Metabolic Epidemiology of Colon Cancer: Fecal Bile Acids and Neutral Sterols
in Colon Cancer Patients and Patients with Adenomatous Polyps” in the (British) Journal of
Cancer, 39, pp 2533-39, 1977 they analyze the quandary as follows:

“The increased enzyme activities of the fecal flora to produce secondary bile acids and cholesterol metabolites
coupled with increased fecal excretion of bile acids and cholesterol metabolites in colon cancer patients compared
to controls raises the intriguing possibility of their role in the etiology of colon cancer.”

“The possibility exists that fecal bacterial 7 alpha-dehydroxylase and fecal cholesterol and its metabolites, and
lithocholic acid and deoxycholic acid, could be utilized as metabolic indicators that will reflect high and low
risk populations as well as patients with colon cancer.”

“The question may be raised as to the extent to which the findings of this and other studies provide (to) causative
explanation to human large bowel [colon] cancer.”

“Although a specific carcinogen for the colon has not been identified in the feces, an association has been
established between colon cancer and fecal excretion of bile acids and cholesterol metabolites.”

“The questions that need to be answered are:

a.) whether carcinogens are present in the colonic lumen or whether they are synthesized by the
colonic mucosa, and
b.) how the bacterial metabolites act and/or interact.”

“In colon carcinogenesis, as is also likely in other forms of chemical carcinogenesis, factors that modify the action
of carcinogenesis may not only play a predominate role in intervention, but also have crucial preventative
significance.”

“From a prevention point of view, studies are required to investigate the dietary changes that can alter the
composition and concentration of intraluminal bile acids and/or cholesterol metabolites.”

“Investigations should be carried out to determine whether adenomatous polyps could be reduced if the
patients were placed on a low fat diet.”

“The data thus generated can significantly enhance our knowledge of the etiological factors that play a role in
cancer of the large bowel.”
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 12

Professor Izrael Hieger, D. Sc. of


London, England, Great Britain (GB)

As in 1977 and still to the present the majority of the leading colon cancer researchers like Professor
Reddy and Doctor Wynder are unaware of the outstanding ground breaking cancer research work
conducted from 1930 to 1965 by Professor Izrael Hieger, D. Sc. of London England, Great Britain (GB)
that identified a “specific carcinogen in the colon” __ cholesterol itself! From 1920 to 1930
Professor Izrael Hieger and his teacher Professor E. L. Kennaway at the Cancer Hospital Research
Institute, London, England, GB. pioneered the study of carcinogenic organic (hydrocarbon)
chemicals. They were the first to isolate and prove the main carcinogenic agent in coal tar and
cigarette smoke was the polycyclic aromatic (unsaturated carbon double bond) hydrocarbon
chemical 3:4-Benz(a)pyrene, which as part of coal tar and asbestos is a major occupational and
environmental cancer vector.

3:4-Benz(a)pyrene

Professor Izrael Hieger and his teacher Professor E. L. Kennaway discovered four attributes about
polycyclic aromatic (unsaturated carbon double bond) hydrocarbon chemical mutagenic
carcinogens as follows:

a.) the mutagenic carcinogenic chemicals are polycyclic aromatic hydrocarbons


made up of condensed or unsaturated double carbon bond rings;

b.) when many substances containing hydrocarbon chemicals are exposed to high
heat they become carcinogenic chemical tars and oils;

c.) when suspected mutagenic carcinogenic chemicals are exposed to ultra-violate


light they give off a fluorescent spectrum of 3 “fluted” bands at 4000, 4180 and
4800 Angstroms measurable with a spectroscope; and

d.) when a suspected carcinogenic chemical is tested by subcutaneous injection into


laboratory mice it produces sarcoma tumors (mostly sarcomatoid carcinomas) at the
point of injection with control groups tested without the substance being tested used.

Hieger and Kennaway’s search and test procedure for carcinogenic chemicals was as follows:

1.) high temperature heating various tars and oils and transforming other substances via high heat into a tar or oil;

2.) ultra-violate light fluorescent spectrum testing them for the 3 characteristic carcinogen “fluted” bands
at 4000, 4180 and 4800 Angstroms; and

3.) systematically testing suspect substances for their mutagenic and carcinogenic abilities by subcutaneously
injecting laboratory mice under stringent controls seeking confirmation by sarcoma tumor production.

In 1930 Professor Izrael Hieger published the results of his ongoing research for other carcinogenic
chemicals at the Cancer Hospital Research Institute in 2 scientific journal articles that tested over 60
tars, oils and other substances as follows:

i.) E. L., Kennaway and Izrael Hieger, I, “Carcinogenic Substances and their Fluorescence
Spectra,” British Medical Journal, pp. 1044 – 46, June 7, 1930; and

ii.) Izrael Hieger, “The Spectra of Cancer Producing Tars and Oils and Related Substances,”
Biochemical Journal, V. 24 (2) pp. 505- 61, 1930.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 13

Incredibly, Professor Izrael Hieger conclusively demonstrated in these 2 scientific journal articles that
Dietary Cholesterol Tar as well as Dietary Animal Meat Tar were mutagenic carcinogens. This does
not portend well for the subject of the carcinogenesis of cooked animal meats. Cooking animal meat is
the only way most human’s can stand to eat it and this is the aboriginal source of the origin of cooked
foods and meals in the first place. In particular the notorious mutagenic and carcinogenic Benz(a)pyrene
cited in Table III #40 permeates charcoal grilled animal meat and Amino-Imidazo Quinolines and
Quinoxalins permeates fried in oil animal meats cited in Table III #42. Clearly it would be safer but
insane to eat animal flesh raw.

It is not a coincidence that Dietary Cholesterol meets all of Professor Hieger and Professor E. L.
Kennaway’s observed characteristics of mutagenic/carcinogenic chemicals of: a.) being a weak
aromatic or cyclic biochemical made up of condensed or unsaturated double carbon bond ring; b.) that
the Dietary Cholesterol Tar gave off the ultra-violate light fluorescent spectrum of 3 bands at 4000,
4180 and 4800; and c.) produced sarcoma’s in laboratory mice.

After over 16 years of painstakingly careful basic research Professor Hieger [now at the Chester
Beatty Research Institute, Royal Cancer Hospital London, England, GB. partly funded by the US Public
Health Service] published 9 scientific journal articles starting in 1946 that conclusively demonstrate
that Dietary Cholesterol is both mutagenic as well as carcinogenic as follows:

1.) 1946 _ Izrael Hieger, “Carcinogenic Substances in Human Tissue,” Cancer Research, V 6, pp 657- 67

2.) 1947 _ Izrael Hieger, “Carcinogenic Activity of preparations rich in Cholesterol,” Nature, V. 160, pp 270- 71

3.) 1949_ Izrael Hieger, “Carcinogenic Activity of Lipoid Substances,” Bri. Journal of Cancer, V. 3, pp 123-39

4.) 1954 _ Izrael Hieger and S.F.D. Orr, “On the Carcinogenic Activity of Purified Cholesterol,”
Bri. Journal of Cancer, V. 8 (2), pp 274-90

5.) 1957 _ Izrael Hieger, “Cholesterol as a Carcinogen,” Proceedings of the Royal Society, B (Biological
Sciences), V. 147, pp 84-8

6.) 1958 _ Izrael Hieger, “Cholesterol Carcinogenesis,” Bri. Medical Bulletin, V. 14, pp 159-160

7.) 1959 _ Izrael Hieger, “Carcinogenesis of Cholesterol,” Bri. Journal of Cancer, V. 8 (3), pp 439-51
Note: The 1959 above cited Izrael Hieger British Journal of Cancer article is attached as Appendix D.

8.) 1960 _ Izrael Hieger, Acta Unio Internationalis Contra Cancrum, V. 15, p. 603, Geneva, Switzerland
Note: This article was so suppressed its “Title” is not retrievable on the Internet, its paper journal resides on
shelve in a few European University Libraries, the journal became defunct in 1964 and has not been
digitized and no abstract of the article exists.

9.) 1962 _ Izrael Hieger, “Cholesterol as Carcinogen_ I. Sarcoma Induction by Cholesterol in a Sensitive
Strain of Mice,” British Journal of Cancer, V 16 (4) pp 716-21

During this over 16 years of painstakingly careful basic research Professor Izrael Hieger, D. Sci. used
three formulated sources of human cholesterol utilized as dietary cholesterol when injected into mice
to study its simultaneous mutagenic and carcinogenic abilities; i.e. a.) an unsaponifiable 85% human
cholesterol liver extract from humans who had died of cancer or died of other diseases; b.) a
commercial human cholesterol source; and c.) a purified 100% human cholesterol preparation
provided by a pharmaceutical manufacturing company further purified.

Professor Izrael Hieger, D. Sci. under total environmental carcinogenic free laboratory conditions and
a controlled research model showed that 2 dietary cholesterol formulations were “slow acting” up
to 19 months latent mutagenic and carcinogenic agents as follows:

1.) mice subcutaneously injected with the unsaponifiable (where all fats have been
removed from the substance with the use of alcohol) basic solvent(s) used to make
soaps and no fatty acids, triglycerides or phospholipids remain 85% human
cholesterol liver extract produced sarcomas at rates as high as 6%; and

2.) mice subcutaneously injected with a purified 100% human cholesterol preparation
provided by a drug manufacturing company produced sarcomas at rates as high
as 14%. Observe that 2 strains of laboratory mice which are herbivore mammals
where injected with “mammalian human cholesterol.”

Thus Professor Hieger’s in vivo research mouse model using our cancer etiological language
distinctions presented above on page 9 was testing Dietary Cholesterol and not Endogenous
Cholesterol as a mutagen and a carcinogen; i.e. the mice as herbivore mammals were forced by
injection to be “mammal cannibals.”
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 14

Thus in 1977 unbeknownst to Professor Bandaru S. Reddy and Ernest L. Wynder, Animal/Dietary
Cholesterol a weak polycyclic aromatic had already been scientifically identified by Professor Izrael
Hieger, in 1959 as the “specific colonic carcinogenic chemical” not only in colon feces, but in the
blood stream and systemically in the entire human body of those humans eating an Omnivorous
Diet. The “association between colon cancer and fecal excretion of bile acids and cholesterol
metabolites” identified by Reddy and Wynder is now readily explainable with Animal/Dietary
Cholesterol scientifically shown by Professor Israel Hieger as mutagenic and carcinogenic with
immediate implications for those eating an Omnivorous Diet.

Predictably, Professor Izrael Hieger, S. Sci.’s research proving that Dietary Cholesterol is
mutagenic and carcinogenic has been suppressed. After his 1961 book review of cancer theories
Carcinogenesis (160 pages) published by Academic Press, Inc., London, England where he includes
dietary cholesterol as carcinogenic he is credited with one more journal research on carcinogens in
1965.

Esoterically, the ingestion of the “slow poison” of Animal/Dietary Cholesterol causes the Liver to
make the primary bile acid Chenodeoxycholic acid (CDCA) as a detoxification product. The Liver
detoxifies CDCA by conjugating it with the amino acid glycine or the sulfonic acid taurine and dumps
the resulting bile salts into the Gall Bladder as detoxed excretory products. Please take note that
although Dietary Cholesterol is predictably mutagenic and carcinogenic being a polycyclic
aromatic but that its detox excretory derivative made by the liver the Primary Bile Acid of CDCA and
its bacterial degradation product the so-called Secondary Bile Acids LCA are only partially detoxed
carcinogenics.

Fortunately, another cancer researcher in London, England bacteriologist Vivienne C. Aries, PhD.
(St. Mary’s Hospital Medical School) from 1969 through 1973 explored the association of
colorectal cancer with industrial countries again albeit Japan. This led her to explore in particular
the dietary cholesterol and bile acid metabolism of 1.) industrial urban English people compared
with rural people of Uganda; and 2.) humans on the Omnivore diet compared with those on strict
Vegetarian diet.

Characteristically, Omnivorous humans have unsanitary chronically infected colons reinforced


daily by their eating more animal meat flesh and organs containing the pathogenic anaerobic bacteria.
The resulting chronic colonic toxemic infections allow these pathogenic anaerobic bacteria to
deconjugate the bile salts neutralizing their Liver’s detoxing. Further bacterial putrefaction
degenerates the un-conjugated CDCA into the carcinogenic agent the secondary bile acid
Lithocholic Acid (LCA).

Professor Vivienne C. Aries verified that 3 major fecal pathogenic anaerobic bacteria the
Bactericides and the Enterobacteria especially E. Coli and Clostridia Bacteria for humans on the
Omnivore diet and on a strict Vegetarian diet possess and use the 7-dehydroxylase enzyme required
to degrade the Primary Bile Acids Cholic Acid (CA) and Chenodeoxycholic acid (CDCA) respectively
into the so-called Secondary Bile Acids Deoxycholic acid (DCA) a weak carcinogenic and into
Lithocholic acid (LCA) strongly carcinogenic.

Professor Aries also discovered [Aries, VC, and Hill, M.J. “Degradation of Steroids by Intestinal
Bacteria II,”, Biochem, Biophys Acta, V. 202, pp. 535, 1970 as reported in op cit, 1971] that the
Bacteriodes bacteria found in Omnivores’ degrade Bile acids greater than those found in Vegetarians;
i.e. where a.) the Bacteriodes spp. of Omnivores have 49% of the 7-dehydroxylase enzyme; and b.)
That Bacteriodes spp. of strict Vegetarians have only 20% 7-dehydroxylase enzyme.

TABLE TWO A below summarizes the pattern found by Professor Vivienne C. Aries [“The Effect of a
Strict Vegetarian Diet on the Faecal Flora and Faecal Steroid Concentration,” British Journal of
Pathology, V. 103, pp. 54-56, 1971] of the fecal neutral steroids (Dietary Cholesterol and its bacterial
metabolite coprostanol) and the primary and secondary bile acids where:

1.) Omnivores have 1.4 times more Dietary Cholesterol and 1.7 times more Total
Fecal Bile Acids including 1.4 times more Fecal CDCA and 2.7 times more Fecal
LCA than strict Vegetarians; and

2) Omnivores have 121 times more Dietary Cholesterol and 3.6 times more Total
Fecal Bile Acids including 26 times more Fecal CDCA and 27 times more Fecal
LCA than Vegans (Herbivores).
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in the Aboriginal Vegan Genotype Human Body ___ p 15-1
TABLE TWO A: FECAL ENDOGENOUS AND DIETARY CHOLESTEROL, COPROSTANAL, PRIMARY AND
SECONDARY BILE ACIDS AND SALTS IN OMINVORES, VEGETARIANS AND VEGANS
Fecal Neutral Steroids (FNS) Fecal Bile Acids and Salts (FBAS)
(mg/g dry weight feces) (mg/g dry weight feces)
Cholesterol Copostanol TOTAL Primary BA Secondary BA Primary BA Secondary BA TOTAL FECAL TOTAL TOTAL TOTAL
Diet FNS Cholonic Deoxycholic Chenodeoxycholic Lithocholic BILE ACIDS & ENDOGENOUS DIETARY CHOLESTEROL
Acid (CA) Acid (DCA) Acid (CDCA) Acid (LCA) SALTS (FBAS)
CHOLESTEROL CHOLESTEROL
[EC] [DC] [EC] [EC] [DC] [DC]
Omnivore 3.3 mg/g 6.8 mg/g 10.8 mg/g 0.5 mg/g 0.3 mg/g 2.6 mg/g 2.7 mg/g 6.1 mg/g 4.1 mg/g 12.1 mg/g 16.2 mg/g
(O) (31%) (69%) (8%) (5%) (43%) (44%)
Vegetarian 1.9 mg/g 5.9 mg/g 8.9 mg/g 0.7mg/g 1.0 mg/g 1.8 mg/g 1.0 mg/g 3.5 mg/g 3.6 mg/g 8.7 mg/g 12.3 mg/g
(V) (21%) (79%)
O/V Ratio 1.7 1.2 1.2 0.7 0.3 1.4 2.7 1.7 1.1 1.4 1.3
Vegan > 1.9 mg/g 0.1 (na) > 1.9 mg/g > 1.7 mg/g 0 0.1 (na) (0.1) na > 1.7 mg/g 3.6 mg/g 0.1 (na) 3.6 mg/g
(VG) - - - -
O/VG Ratio 1.7 68.0 (na) 5.7 0.3 3 26.0 (na) 27.0 (na) 3.6 1.1 121 (na) 4.5
Adapted from Aries, Vivienne C., et al, “The Effect of a Strict Vegetarian Diet on the Faecal Flora and Faecal Steroid Concentration.” British J. Pathology, V 103, pp 54-6, 1971.
KEY: EC _ Endogenous Cholesterol or derived there from, DC _ Dietary Cholesterol or derived there from, na _ Not Applicable.
NOTES: I. a.) Since Omnivores ingest animal meat and dairy and strict Western Vegetarians as used in this research ingest dairy products containing rennet (cow milk sack scrapings used to coagulate cheese],
about half of their ingested Dietary Cholesterol which is mutagenic and carcinogenic is made by the Liver into the so-called Primary Bile Acid Chenodeoxycholic Acid (CDCA) which is
still a weak carcinogenic;
b.) Then the Liver further detoxifies the Chenodeoxycholic Acid (CDCA) by conjugating it with either the amino acid glycine or with the sulfonic acid taurine making the CDCA Bile Acid Salts
where it is stored in the Bile of the Gall Bladder which will release it into the small intestine intended for excretion via the body feces.
I. c.) Unfortunately however, in Omnivores and in most Western Vegetarians when the Gall Bladder releases its Bile with the Primary Bile Acid Salts of Chenodeoxycholic Acid (CDCA) into the small
intestine food chime it is instead of fecal excrement is deconjugated from the amino acid or sulfonic acid detoxifier and further degraded in the Toxemic large intestine by Pathogenic Anaerobic
Bacteria transformed into the so-called Secondary Bile Acid Lithocholic Acid (LCA) an even stronger carcinogen than CDCA.
Furthermore the large intestine’s Toxemic condition allows for the Pathogenic Anaerobic Bacteria to further degrade LCA producing so-called Tertiary Bile Acids many of which are
cyclic aromatic biochemicals and thus potentially mutagenic and carcinogenic and highly transient. See text and Table Three for further detail.
II. Additionally in Omnivores and Vegetarians the other half of their Dietary Cholesterol is made by the Colonic Pathogenic Anaerobic Bacteria into the Neutral Steroids Coprostanol (Coprosterol)
and Coprostanone.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” ________________________________ p 15-2

The below Tables 1,2, 3 & 5 from van Faassen, Arendina, et al, ”Bile acids, neutral steroids, and bacteria in feces as
affected by a mixed, a lacto-ovovegetarian, and a vegan diet”, American Journal of Clinical Nutrition, V. 46, pp 962-7,
1987 show the same pattern as the Table from Aries above.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 16

TABLE THREE below inventories the scientifically confirmed mutagenic, carcinogenic, atherogenic,
cholelithiasis (gallstone formative) and cytotoxic agents in the etiology of colorectal and other cancers,
cardiovascular, stroke and other Dietary Cholesterol and Related Diseases and
Syndromes. Please take note there are 39 substances so inventoried which are Dietary Cholesterol
or derivatives produced from it in the body by various organs, spontaneously or by pathogenes!

Tertiary Bile Acids are short lived, hard to detect and are produced by the 3 major fecal pathogenic
anaerobic bacteria Bacteroides, Enterobacteria and Clostridia. Especially dangerous are the “NDH
(‘A ring’ Nuclear Dehydrogenating)” capable Clostridia [Lecithinase enzyme (-) negative] that form
aromatic (unsaturated) cyclic structured Tertiary Bile Acids that by definition are suspected as
mutagenic and carcinogenic. Thus in Toxemic colon conditions the Bacteroides Bacteria can degrade
Dietary Cholesterol to a 3-alpha, 6-alpha dihydroxyl bile acid which in turn can be further metabolized
by Lecithinase enzyme (+) positive Clostridia Bacteria to 6 alpha-hydroxl-5 beta cholan-3 Oxo-24 oic
acid and then converted by NDH capable Clostridia (Lecithinase enzyme (-) negative) into the known
mutagenic and carcinogenic Tertiary Bile Acid 6-Alpha Hydroxychol-4 ene-3 –none oic acid.

The free Endogenous Cholesterol that the Liver excretes into the gall bladder and released by it into the
small intestines is degraded in the Toxemic colonic conditions by pathogenic anaerobic bacteria
especially the 3 major fecal Bacteroides, Enterobacteria and Clostridia Bacteria in humans on the
Omnivore diet and on a strict Vegetarian diet resulting in the following non-mutagenic and non-
carcinogenic fecal Neutral Steroids:

a.) Endogenous Cholesterol (5 cholesten 3-beta- ol)


Note: Natural (Endogenous) Cholesterol by definition made in the host human body is not
mutagenic nor carcinogenic in that body.

b.) coprostanol (5 beta cholestan 3 beta- ol) __ the main fecal steroid

c.) coprostanone (5 beta cholestan 3 one)

d.) triol (cholestane – 3 beta, 5 alpha, 6 beta –triol) __ weakly carcinogenic and toxogenic

However, any remaining Dietary Cholesterol [that escapes being converted by the Human Liver to the
toxic Primary Bile Acids CA and CDCA and further detoxification mostly to their glycine and a taurine
conjugated Bile Salts] in the Toxemic colonic conditions [of the predominate 3 fecal pathogenic
anaerobic bacteria Bacteroides, Bifidobacteria and Clostridia in humans on the Omnivore diet and
strict Vegetarian diet] is catabalized into cholestenone (4 cholesten 3 - one). Predictably, since
Cholestenone (4 cholesten-3 - one) as the result of the degradation action of the NDH clostridium
Bacteria is a “4 ene - 3 one” class or aromatic cyclic steroid it is a suspected carcinogenic.
Indeed as indicated in TABLE THREE in vitro animal studies have confirmed that cholestenone is a
mutagenic and carcinogenic. [F. 17]

Please note that isomers of Animal/Dietary Cholesterol both “Natural_ 3 Beta” and “Enantiomer _
3 Alpha” are major mutagenic carcinogens in human colorectal cancers. The Medical Sciences
and Organic Steroid Chemistry are corrupted by promulgating that the human liver metabolizes
Endogenous Cholesterol into the C-24, 3-alpha Primary Bile Acid CDCA and 3-Beta-5-Cholenoic
acid when in fact only Dietary Cholesterol is the source of the C-24 3-Beta and 3-Alpha Bile Acids
and isomers of CA, CDCA with the intestinal Toxemic bacteria degrading them to DCA and LCA.

D. Secrets of Dietary Cholesterol and Bile Acid Metabolism

In 1976 two years after T. Narisawa’s ground breaking 1974 article associating the secondary bile acid
LCA with colon cancer, Professor D.P. Burkitt, PhD. an external staff of the British Medical Research
Council published another ground breaking article entitled “The Etiological Significance of Related
Diseases” in the Canadian Family Physician Journal, V. 22 (999) pp 64-71. He discloses that his 40
years of clinical medical experience and 3 year questionnaire investigation of hospital staff in developing
countries had lead to the hypothesis that the following diseases “among the prevalent complaints in
the western world today are closely associated with one another” and that they ”share some
common causative factor” as follows:

a.) Ischemic heart disease f.) Hemorrhoids

b.) Gallbladder disease g.) Varicose vein

c.) Appendicitis h.) Hiatus hernia

d.) Diverticular disease i.) Obesity

e.) Colorectal cancer j.) Diabetes Mellitus


THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 18

The common cause Professor Burkitt identified was the lack of dietary fiber in the modern
Western diet. Clearly, in hindsight he almost figured out the DCRDS and their common cause.
Surely the use of the refined carbohydrates we call the “5 white foods” of white flour, white sugar,
white table salt, white rice and rennet containing dairy products is a secondary factor with
constipation being the common symptom. Everyone knows animal meat is without any significant
fiber and constipating.

Please find attached the Dietary Cholesterol Related Diseases and Syndromes (DCRDS)
Systems Analysis Body Flow Chart for a composite relational and causative picture of the "great
pathophysiological ramifications of bile acid metabolism." The DCRDS Systems Analysis
Body Flow Chart is hand scribed and 5 color coded for ease of navigational reading and systems
synthesis simulation as follows:

* green for the 9 step Food Ingestion, Digestive and Elimination System;
* yellow for organs;
* red for the blood stream;
* blue for "bile acid metabolism;" and
* orange for a member of the Top Fifteen Killing Diseases of Americans (TFK’s) in 2006

For those reading a flow chart for the first time it is made up of Systems Analysis basic building
block the subsystem component itself composed of 3 elements a.) input arrow to b.) a process (like
an organ) and c.) an output arrow leaving the process. "Everything is everything" and so in the world
and universe anything can be accurately so described and simulated via Systems Analysis.

From the synthesis of in vitro and in vivo primary health research and epistemological/observational
research the simulation of the DCRDS Systems Analysis Body Flow Chart deduces that Thirteen
(13) of the Top Fifteen Killing (TFK) Diseases in America in 2006 can be identified as Dietary
Cholesterol and Related Diseases and Syndromes (DCRDS).

TABLE FOUR: Thirteen of Top Fifteen Killing (TFK) Diseases Identified as Dietary Cholesterol and
Related Diseases and Syndromes (DCRDS): Results of the DCRDS Systems Analysis Body Flow
Chart presents these synthesis simulation deduction results.

It is herein declared that it has been documented and simulated by the DCRDS Systems Analysis of
the Human Body Flow Chart that thirteen (13) of the Top Fifteen Killing (TFK) Diseases in America
in 2006 can be identified as Dietary Cholesterol and Related Diseases and Syndromes (DCRDS)
caused by Dietary Cholesterol and its associated Animal Protein and Animal Fat residues from
the American high fat/high protein modern refined food Omnivores Diet particularly from the fast
food venues as follows:

#1. Heart Diseases

#2. the Cancers

#3.' Iatrogenic Disease (physician/health care system caused)

#3. Stroke

#4. Asthma/Emphysema/Bronchitis

#6. Diabetes Mellitus

#7. Alzheimer's Disease

#8. Influenza/Pneumonia

#9. Kidney Diseases

#9.’ Iatrogenic Poverty

#10. Septicemia

#11. Suicide

#12. Liver Diseases

#13. Hypertension

#14. Parkinson's Disease


THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 19

TABLE FOUR:
Thirteen of the Top Fifteen Killing (TFK) Diseases Identified as Dietary Cholesterol and Related
Diseases and Syndromes (DCRDS): Results of the DCRDS Systems Analysis Body Flow Chart

Common Disease/Syndrome Name Dietary Cholesterol & LCA Bile Acid Implicated (C-B) Animal Lipoprotein
Implicated (L-P)
(Medical Science Name) [ Primary (P) Secondary (S) ] [ Primary (P) Secondary (S) ]

#1. Diseases of the Heart

a. Heart Attacks S P
(Myocardial Arrest and Infarction)

b. Heart Failure P
(Congestive Heart Failure)

c. Heart Block S P

#2. Cancers
[ 60% Obesity Associated
except Brain, Bladder,
Skin)

a. Lung P S

Excluding
Tobacco Smoking

b. Colorectal P S

c. Breast (Female) P S

d. Prostrate (Male) P S

e. Non-Hodgkin Lymphoma P S

f. Skin P
(Melanoma)

g. Kidney P S
(Kidney/Renal/Pelvic Area)

h. Urinary Bladder P

i. Leukemia P S

j. Ovary/Womb/Cervix P P

k. Thyroid (Female) S P

l. Others P

#3.' (Iatrogenic)
Doctor Caused P [Not Taught BA Metabolism S [Not Taught Proper
or Proper Human Diet] Human Enteric
Hygiene]

#3. Stroke S P

#4. Asthma/Emphysema/Bronchitis S P

#5. Accidents S S

#6. Diabetes Mellitus P P

#7. Alzheimer's Disease P S

#8. Influenza and Pneumonia S P

#9. KIdney Diseases S P

#10. Scepticemia S S

#11. Suicide S P

#12. Liver Disease and Cirrhosis P S

#13. High Blood Pressure P P

#14. Parkinson's Disease P S

#15. Assaults NOT APPLICABLE NOT APPLICABLE


THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 20

Note when "walking through" the DCRDS Systems Analysis Body Flow Chart remember that the
over 70 year old suppressed secrets of "dietary cholesterol and bile acid metabolism" is based
on the fact that humans are genetically herbivores like rabbits and mice and not omnivores like
rats and dogs; i.e. omnivore humans can only convert 1/3 of the Dietary Cholesterol they ingest
into bile acids and must excrete the other 2/3 as Dietary Cholesterol through the feces
compounding the Toxemic colonic cesspool environment there. The Omnivore dog and rat can
convert 2/3 of their ingested Dietary Cholesterol in comparison.

1.) Endogenous Cholesterol (nat-Cholesterol) is synthesized in the human body made


mostly by Liver and Small Intestinal Mucosal Cells where normally about half of it is
metabolized by the human Liver into the esoteric true or aboriginal natural primary bile
acid of Cholic Acid (CA) and stored in the Gall Bladder for fat emulsification and fecal
elimination from the body mostly conjugated with the amino acid Glycine and the “so-
called” amino acid Taurine as bile salts.

Cholic Acid
(CA)

Note: In the human body eating the aboriginal Vegan diet the bile acid Cholic Acid (CA) is the natural
primary bile acid derived from about half of the Endogenous Cholesterol and used by the body
to emulsify fats in the small intestine food chyme and is conjugated with endogenous amino
acid Glycine as a bile salt.
Note: In the human body eating the unnatural Dietary Cholesterol intense Omnivore diet in addition
to the liver making the primary bile acid Cholic Acid (CA) naturally derived from the liver
synthesized Endogenous Cholesterol [and used by the body to emulsify fats in the small
intestine food chime and is conjugated with endogenous amino acid Glycine as a bile salt]; the
human liver detoxes the “slow poison” of Dietary Cholesterol into the so-called primary bile acid
actually a detox product Chenodeoxycholic Acid (CDCA) which is conjugated with both the
endogenous and exogenous/dietary amino acid Glycine and dietary sulfonic acid Taurine as
bile salts
Note: It is no secret that where there is a failure of the body to provide enough Lecithinase to transform
all of the free Dietary Cholesterol in the blood that has accumulated in the body from the
unnatural Dietary Cholesterol intense Omnivore diet into LDL-cholesterol esterified to fatty
acids there will result clinical cases of anemia, high concentrations of putrefactive animal
derived proteins in the blood, urine tissues and organs (proteinuria, amyloidosis); renal
failure and corneal opacities.
The etiology of DCRDS whose symptoms include fibrous protein deposits and placque
formations are so linked; e.g. the heart diseases, Alzheimers, Diabetes Mellitis and the
lymphomas and leukemic cancers involving mutagenic immunological clone white blood cells.

2.) Normally about half of the Endogenous Cholesterol made by the human liver or small
intestinal cells is in turn synthesized by the liver into various precursors of vital human
steroid body products as follows:

a.) for making cell membranes throughout the body composed of polysaccharides
and fatty acids with Endogenous Cholesterol itself a crucial component.

b.) for making Vitamin D3 by the human skin with proper solar radiation.

c.) for making Adrenocortisone hormones by the Adrenal Glands including:


1.) the mineralocorticoids that help control the body’s water and electrolyte balance; and
2.) the glucocorticoids that help control the body’s glucose metabolism.

d.) for making male Androgen (male) and Estrogen (female) sex hormones by the
respective sex's testicles or ovaries and to lesser extent by the Adrenal Glands’ cortex portion.

3.) Dietary Cholesterol from eating mammal, non-mammal including fish and insect meat, dairy
products and eggs as “pseudo foods” is detoxified and broken down by the Human Liver via
the Cholesterol 7- alpha hydroxylase enzyme into the so-called (misnamed) primary bile acid
Chenodeoxycholic Acid (CDCA) and dumped into the Gall Bladder for fecal elimination from the
body mostly conjugated with the amino acid Glycine and the “so-called” amino acid Taurine in
bile salts or as the bile acid.

Chenodeoxycholic Acid
(CDCA)
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 21

4.) Additionally, Dietary Cholesterol from eating mammal, non-mammal including fish and
insect meat, dairy products and eggs as “pseudo foods” absorbed into the blood stream is
partly detoxified by the vascular and kidney endothelial cells via the Sterol27-hydroxylase
enzyme into various oxy-Cholesterols, and when absorbed into the liver are further detoxed
into the primary bile acid Chenodeoxycholic Acid (CDCA) and dumped into the Gall Bladder
for fecal elimination or urine elimination from the body.

5.) Dietary Cholesterol can not be properly made by the Human Liver into the various precursors
for making human cell membranes systemically, Vitamin D3 in the Skin, Adrenocortisone
hormones by the Adrenal Glands and the Male and Female Hormones by the respective sex
gonads and to a lesser extent by the Adrenal Glands.

6.) The so-called "Secondary Bile Acid" of Deoxycholic Acid (DCA) is actually not made by the
Human Liver but derived from the Primary Bile Acid of Cholic Acid (CA) by putrefactive
anaerobic pathological bacteria in the Human Colon. This results from an unsanitary
cesspool colonic environment which everyone eating animal meat and/or dairy or have eaten
animal meat and dairy have without exception allowing anaerobic bacterial Toxemic degradation
of the Primary Bile Acid CA intended as an excretory product by the Liver from Endogenous
Cholesterol.

Deoxycholic Acid
(DCA)

Note: The Primary Bile Acid of Cholic Acid (CA) is a natural excretory product made by the Liver from
Endogenous Cholesterol, and is found in its Bile Salt form conjugated with the amino acid Glycine
or the sulfonic acid Taurine in the Bile released by the Gall Bladder into the small intestinal tract.
Subsequently, the Primary Bile Acid of CA is bacterially degraded into the so-called "Secondary
Bile Acid (SBA)" called Deoxycholic Acid (DCA) in the Colonic Toxemic environment. DCA is not
strongly associated with the etiology of colorectal cancer; i.e. a weak co-carcinogen.

6’.) The so-called "Secondary Bile Acid (SBA)” of Lithocholic Acid (LCA) is derived from the so-
called Primary Bile Acid of Chenodeoxycholic Acid (CDCA) as a result of ingesting Dietary
Cholesterol from the Omnivore Diet and to a lesser extent from the Vegetarian Diet not in the
Human Liver but in the Human Colon by putrefactive anaerobic pathological bacteria. This
results from an unsanitary “cesspool” colonic environment which everyone eating animal meat
and/or dairy or who have eaten animal meat and/or dairy with the subsequent mucus waste
residues have without exception. This “cesspool” condition leads to further anaerobic bacterial
Toxemic degradation of the Primary Bile Acid CDCA itself a detox product derived by the Liver
from Dietary (Exogenous) Cholesterol.

Lithocholic Acid
(LCA)

Note: The Primary Bile Acid of Chenodeoxycholic Acid (CDCA) is a detox product derived by the
Liver from Dietary (Exogenous) Cholesterol and is found in its Bile Salt form conjugated with
the amino acid Glycine or the sulfonic acid Taurine in the Bile released by the Gall Bladder into
the intestinal tract. Chenodeoxycholic Acid (CDCA) is strongly associated with the etiology of
colorectal cancer.

Subsequently, the Primary Bile Acids of CDCA is bacterially degraded into the so-called
"Secondary Bile Acid (SBA)" called Lithocholic Acid (LCA) in the Colon (large Intestines) in
a Microbial Toxemic enteric environment. LCA is the most powerful biological carcinogenic
known in science inducing DNA strand breaks, forms DNA adducts, inhibits DNA repair enzymes
and promotes colon cancer in animals (rats). Lithocholic Acid (LCA is strongly associated with
colorectal cancer as a carcinogenic agent.

7.) The Microbial Toxemic enteric environment producing the so-called “Secondary Bile Acids”
DCA and LCA is populated by the pathogenic facultative anaerobic (fa) and obligate anaerobic
(oa) bacteria including the Escherichia. Coli (fa) Bacteroides (oa), Clostridium (oa) and
Eubacterium (oa) as the lead, deconjugating the Primary Bile Salts amino acid glycine and
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 22

sulfonic acid taurine to free Primary Bile Acids which allows for easier pathogenic degradation
to the "Secondary Bile Acids" DCA and LDCA.

Note: Vitamin D3 that prevents colorectal cancer deactivating LCA is made in human skin via UVB
solar Radiation is itself derived from a precursor made by the liver from Endogenous Cholesterol.
Note: Since it is found in high concentrations in humans with colorectal cancer LCA is deduced as
producing colorectal cancers and all the rest in most cases of the cancers where industrial,
agribusiness chemicals and cancer causing viruses are ruled out.
Note: Professor Jin Li Tong, PhD. of Yonsei University of Japan article entitled “Association between Fecal
Bile Acids and Colorectal Cancer: A Meta-analysis of Observational Studies”, Yonsei Med J.; V 49(5):
792–803, October 3, 2008 has confirmed that the Dietary Cholesterol derived Primary Bile Acid
CDCA and its anaerobic degradation product the Secondary Bile Acid Lithocholic Acid (LCA)
are significantly associated with colorectal cancer etiology as carcinogenic agents.

8.) The sudden appearance over the last 30 years of Metabolic Syndrome (Met S.) affecting over
20% of the Americans can involve simultaneously 9 risk factors for obesity, diabetes mellitus
Type II, hypertension, and cardiovascular heart disease. Etiological suspect are the coinciding
increased Dietary Cholesterol containing modern American high animal protein and fat fast food
diet, and the extensive use of blood cholesterol lowering prescription drugs most notably the
“statins” targeting decreasing the liver’s natural production of Endogenous Cholesterol.

9.) America’s deteriorated high Infant Mortality Rate is related to the “great ramifications of dietary
cholesterol and bile acid metabolism” and the proliferation of the high fat and protein fast food
diet. This is because the human is genetically programmed as a herbivore/vegan as discussed
in Appendix A-1. Ironically, under the unnatural environment of a maternal Omnivore diet the
liver and other organs of the human fetus processes Dietary Cholesterol as a “slow poison.”
To survive the fetus uniquely utilizes a “Third Bile Acid Metabolic Pathway” initiated by cellular
mitochondria. The DNA of mitochondria of mother and child are identical. This herbivore/
vegan genome dictated bile acid metabolism persists from conception up to about 4 years of age.
Thus human fetuses, neonatals and infants uniquely produce highly toxic bile acids as follows:

a.) as their primary bile acid the 3-beta-Hydroxy 5 Cholenoic acid [an at risk cholestatic
(gallstone producing) C-24 monohydroxy bile acid with an at risk mutagenic and
carcinogen (cancer promoting) aromatic (unsaturated) polycyclic structure];

b.) as their secondary bile acids the various isomers of Lithocholic Acid [also a
cholestasis at risk C-24 monohydroxy (saturated) bile acid produced by the liver
without as in adults the pathogenic anaerobic bacterial gut degradation]; and

c.) the tertiary bile acids the so-called normal bile acids CA and CDCA (C-24 3-alpha).

Environmental pollution of the nation’s urban and rural water ways with plastic packaging, containers,
cups, plates and other eating utensil generated litter leaches UV light degraded plastic mutagenic and
carcinogenic compounds into the water table endangering not only human fetuses, neonatal and infants
but adult human as they produce various C-24 mono- and poly- hydroxy bile acids many with aromatic
polycylic rings known to promote if not cause mutations, cancer and organ necrosis.

E. Obesity and the Occurrence of the Cancers and the Other DCRDS

Marine Biologist and Naturalist Rachel Carson (1907 -1964)

The book Silent Spring released in 1962 by marine biologist and naturalist writer Rachel Carson
(1907-1964) coined the concept of environmentalism by exposing the damage of pesticides especially
the polycyclic aromatic hydrocarbons (PAH) found again always as strong suspects for mutagenic
and carcinogenic effects in wildlife concentrating at the top of the food chain. It was Silent Spring’s
prophetic warning that alerted the government and the people to the systemic pollution that pesticides
were having deforming and killing the predator birds like the bald eagle.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 23

It was her Silent Spring that got the federal government to ban the use of the insecticide DDT
(Diclorodiphenyl Tricloroethane) in America although it is still used in Mexico to grow food produce
imported into America to this day.

DDT (Diclorodiphenyl Tricloroethane, PAH)

DDT collects in the adipose (fat) tissue of humans as that is what the liver does with poisons it can
not detoxify using the fat tissues of the body as a dumping ground where they have a cumulative effect.
This makes the US/Food and Drug Administration single chemical testing paradigm obsolete and
ineffective because it ignores this toxic waste dump role of adipose (fat) tissue in the human body. Fat
analysis as a diagnostic and preventive sickness tool is lacking in America as discovered by PBS
Investigative Journalist Bill Moyer who upon exposing the dangers of polyvinyl chlorides (PVC’s)
had over 148 different chemicals identified in his own fat tissue.

Note that obesity has been found 60% associated with the incidence of all cancers except brain,
skin and bladder cancer; because the Omnivore’s adipose tissue’s many dumped mutagens and
carcinogens are exploited by Dietary Cholesterol derived bile acids as further co-carcinogens.

Note that obesity has been shown associated with Diabetes Mellitus Type II; has been shown
associated with Hypertension (High Blood Pressure); has been associated with heart diseases and
is one of the 9 risk factors of Metabolic Syndrome.

The etiology of obesity and the related overweight condition is directly related to the ingestion
of animal flesh/organ and rennet containing dairy “pseudo” foods because dietary animal fat
can not be properly combusted by the human body for energy needs and is treated by the liver
as a waste dumped into the adipose tissues. The Vegan Diet relieves obesity and overweight
conditions by reversing them.

F. The “So-Called” Amino Acid Taurine and Bile Acid Metabolism

The Human Liver also is responsible for the deactivation and elimination of dead, damaged and used up
human cells all of which contain Endogenous Cholesterol in their cell membranes. Thus the Liver must
get rid of human cell membrane fatty acid esterified Endogenous Cholesterol which is broken down
into the primary bile acid CA and dumped into the Gall Bladder for fecal elimination from the body as a
bile acid or as a bile salt conjugated predominately with the amino acid Glycine and to a lesser extent
with the sulfonic acid Taurine.

A detailed study of the interrelationship of the “so-called” amino acid Taurine with the bile acids in terms
of their ingestion, synthesis and metabolism in the human body and in the domestic grazing animals that
Omnivore Diet humans eat is instructive on the ill effects of eating Dietary Cholesterol and associated
Animal Protein (Amino Acid) and Animal Fat residues. In so doing misconceptions of allopathic
medical sciences generated by the suppression of "the great pathophysiological ramifications of
dietary cholesterol and bile acid metabolism" appear.

The human body immune system requires the mineral element Sulfur (S) which is found in the vitamin
Biotin and in the following amino acids Methionine (Meth), Cysteine (Cys), Homocisteine (Hcy), the
di-peptide Cystine and the misclassified “amino acid” Taurine (Tau). In the human Omnivorous Diet
these Sulfur containing vitamins, amino acids and di-peptides are derived from Dietary Animal Sources,
Plant Sources and/or are in the case of Cys, Hcy and Cis synthesized by the Liver in the human body.

Taurine (TAU) is named after the Latin word “taurus” for bull/ox because it was first isolated from a bull’s
horn. It is plentifully found in the bull’s semen and urine. The allopathic biochemical science
suspiciously misclassifies Taurine as an “amino acid” as does the Stedman Medical Dictionary. Yet
Taurine actually is a “sulfonic organic acid” not having a carboxyl (-COOH) group which helps define
the biochemical nature of an “amino acid.” Taurine is derived in the human body from dietary animal
protein or dietary plant protein from the catabolism of the amino acid Cysteine which is a generic cell
membrane structural element in both animals and plants especially in the latter found in the grasses.
But Taurine is not essential for human health. No known plant or animal can metabolize it once it is made.
So in mammals like cows and humans Taurine is excreted in their urine and in their fecal eliminations
found conjugated with bile salts and bile acids.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 24

Esoterically, this Allopathic biochemical misclassification of Taurine as a so-called amino acid is a


reflection of the over 35 years of the suppression of "the great pathophysiological ramifications of
dietary cholesterol and bile acid metabolism" in this case suppressing the related “ramifications of
proteins and amino-acid metabolism.” Further proof of this is reflected in Taurine having no known
mRNA genetic coding in the human genome; yet it is allowed by the Food and Drug Administration
(FDA) to be added to energy drinks and used as a health supplement for various unproven benefits.

In the human being Taurine is made as a detox product in the liver from largely Dietary Animal Derived
Amino Acid Cystine itself made from the Dietary Animal Derived Di-Peptide Cysteine which are both
ingested as various tissue cellular components derived by the food industry largely from duck feathers.
Cysteine and Cystine are used by mammals including human hair, nails, skin and connective tissue as
part of the protein Keratin. The non-essential human amino acid Cysteine is synthesized in humans in
the Liver from the amino acid Homocisteine itself derived from Methianine. Cysteine is used by the skin
epidermal, vascular endothelial, respiratory and intestinal mucosal cells for making their cell membranes.

Cysteine is found extensively in the plant foods humans ingest. It is found plentifully in the grasses and
thus in the meat of domesticated grazing animals the cow, sheep and goats Omnivores eat. Sheep need
Taurine in their feed if grass is not available from drought for example. Domestic cats as carnivores need
Taurine in their feed, and wild animal feline species like lions and leopards eat the innards of their prey
first as the intestinal tract herbal contents contain the Cysteine they need. Thus It is no coincidence
that high serum levels of Homocystein which is formed from Dietary Cysteine from eating meat is
a degradation product of E. Coli in the toxemia of the colon is a risk factor for cardiovascular
disease and reflects a Vitamin B complex deficiency.

The human body synthesizes the amino acid Cysteine from Homocysteine and it is part of human hair,
skin and nails as the protein Keratin. Yet high levels of serum Homocysteine is a risk factor for
cardiovascular heart disease (CVHD). Is this excess Homocysteine made by the body or is it derived
from Exogenous (Dietary) animal cell membranes and connective tissue eaten as animal “pseudo”
foods? Esoterically, as with Dietary Cholesterol the related Dietary Animal Protein of Cysteine and
Cystine constitute dietary contaminants showing up as elevated levels of serum Homcycteine in
CVHD and Taurine showing in the urine and conjugated with Bile Acids as determined by the liver.

G. The Cholesterol Reducing Drugs and the Manifestation of Metabolic Syndrome

The sudden appearance over the last 30 years of Metabolic Syndrome (Met S.) affecting over 20%
of Americans can involve simultaneously 9 risk factors for obesity, diabetes mellitus Type II,
hypertension, and cardiovascular heart disease. Etiological suspect are the coinciding increased
Dietary Cholesterol containing modern American high animal protein and fat fast food diet, and the
extensive use of blood cholesterol lowering prescription drugs most notably the“statins” targeting
decreasing the liver’s natural production of Endogenous Cholesterol.

This is a dangerous etiological mixture as Dietary Cholesterol “down regulates” the synthesis of natural
Endogenous Cholesterol leading to: a.) a deficiency of the Vitamin D3 hormone of antioxidant,
anticancer and metabolic and growth functions as 7 Dehydoxycholesterol its precursor is made from
Endogenous Cholesterol; b.) deficiencies of mineralocorticoid hormones and c.) deficiencies of the
glucose metabolic control hormones the glucocorticoids (cortisone, hydrocortisone) made by the
adrenocortex glands as its precursors too are made from Endogenous Cholesterol.

Note: The Met S. 9 risk factors cited are a.) increased waist circumference (obesity and overweight conditions);
b.) elevated blood triglycerides;
c.) low blood HDL cholesterol;
d,) high blood LDL cholesterol;
e.) high blood uric acid;
f.) high blood pressure;
g.) fasting blood glucose;
h.) increased blood coagulation;
i.) in women high androgen levels; and
i’.) in men high estrogen levels.

The Omnivore diet eating individual has the following physiological “daily cholesterol dilemma”
on such a mixed diet ingesting Dietary Cholesterol and body making Endogenous Cholesterol:

1. The average Vegetarian diet eating adult’s liver makes about an average of 800 mgs/day
of Endogenous Cholesterol and this is an aboriginal standard for natural cholesterol
synthesis daily for the human body as a cholesterol deficiency is not clinically known or
observed in a human with a healthy liver.

2. The average Omnivore diet adult eating the typical high animal protein and fat fast food high
diet consumes 500 to 900 mg/day of Dietary Cholesterol.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 25

3. Thus the average Omnivore diet adult theoretically metabolizes a combined 1300 to 1700
mg/day of Endogenous and Dietary Cholesterol.

4. In the body of average Omnivore diet adult half of the ingested Dietary Cholesterol is used
to make the toxic bile acid CDCA. The other half remains in the body largely in the blood stream
as LDL-cholesterol.

Note: This potentially high concentration of serum/blood LDL is a risk factor for the Heart
Diseases, Hypertension, Liver Disease, Kidney Disease, Diabetes Mellitus and of
course Metabolic Syndrome.

5. Normally, in the body of an average Omnivore diet adult half of the synthesized Endogenous
Cholesterol would normally be transformed into the non-toxic primary bile acid Cholic Acid (CA)
which is stored in the Gall Bladder to act as a detergent to help break up dietary fats for digestion;
while the other half of the Endogenous Cholesterol is made into various body steroids by the Liver.

6. Abnormally however, Dietary Cholesterol ”down regulates” the liver from making Endogenous
Cholesterol and its steroid hormone precursors by:

a.) suppressing the making of the required cholesterol synthesis enzyme HMG Co-A Reductase;

b.) toxically inactivates the required cholesterol synthesis enzyme HMG Co-A Reductase the
enzyme already synthesized; and the corresponding decrease in Endogenous Cholesterol
translates into a corresponding decrease in its production of steroid hormone precursors; and

c.) as previously described the allopathic medical sciences and their pharmaceutical industry
funding and distribution allies are exploiting the knowledge of “cholesterol and bile acid
metabolism” with synthetic biochemical inhibitors of the liver’s natural synthesis of
Endogenous Cholesterol by targeting the blocking of the require enzyme HMG Co-A
Reductase (3-hydroxy-3-methylglutaryl-Coenzyme A reductase) with a variety of blood
cholesterol reduction drugs like HMG-CoA reductase inhibitors called the "statins."

Esoterically by targeting the enzyme HMG Co-A Reductase with the objective of lowering “bad” LDL
Cholesterol in the blood and raising “good” HDL Cholesterol the overall effect in the American
population is a shortage of the precursors made by the liver only from Endogenous Cholesterol with
the following “pathophysiological ramifications” of vital human hormone, vitamin deficiencies and
sub-clinical and clinical Metabolic Syndrome symptoms including:

i.) shortage of colon cancer preventing Vitamin D3 in youth and adults yielding higher blood glucose
levels higher blood pressure and free high cholesterol blood levels;

ii.) shortage of adrenocortisone hormones and resulting proliferation of Metabolic Syndrome with its 9 risk
factors [a.) increased waist circumference; b.) elevated blood triglycerides; c.) low blood HDL
cholesterol; d,) high blood LDL cholesterol; e.) high blood uric acid; f.) high blood pressure; h.) fasting
serum blood glucose; i.) higher blood coagulation; j.) in women high androgen levels and k.) in men high
estrogen levels];

iii.) a shortage of androgen male sex hormones and a proliferation of Penis Erectile Dysfunction (ED)
Syndrome of 50% of males over 50 years old ironically addressed by the pharmaceutical ED
treatment drugs Viagra and Cialis; and

iv.) shortage of estrogen female sex hormones and proliferation ovarian cancer, of Premenstrual Syndrome
(PMS) and menopausal and post menopausal complications of 50% of females over 50 years old.

Again of notable exception to allopathic physicians missing this problem is Dr. Dean Ornish, MD.,
Director of the Preventive Medicine Research Institute whose astute June, 2002 editorial in the
American Journal of Cardiology (AJC) “Statins and the soul of medicine”, V. 89, pp. 1286-1290, takes
issue with this questionable drug therapy.

In summary, it is hereby declared that the proliferation of America’s fast food high fat diet with
increased per capita daily Dietary Cholesterol over a period of time reduces the Human Liver's
production of Endogenous Cholesterol by suppressing the synthesis of the required enzyme HMG
Co-A Reductase and inactivating the existing enzyme. Thus proportionately the Liver's production
of the various precursors for making systemic cell membranes, Vitamin D3, the Adrenocortisone
hormones and the sex gonads Male and Female Sex Hormones is reduced.

Additionally, with the increase especially since 1985 of “statin” prescription cholesterol lowering
drugs an etiological association has appeared with Metabolic Syndrome affecting over 20% of
Americans with obesity, hypertension, cardiovascular heart disease and diabetes mellitus risk factors.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 26

H. The Sanitation of the Human Body Blood Stream is the Key to Health

The question here is: Why are so many chronic diseases and syndromes that annually kill
Americans associated with Animal/Dietary Cholesterol and its related Animal Protein and Animal
Fat residues?

The answer lies in the DCRDS Systems Analysis Body Flow Chart as 9 specific ramifications
from the ingestion of Animal Dietary Cholesterol, DNA, Protein and Fat residues as follows:

1.) Intestinal Anaerobic Pathogenic Bacteria Fermentation of Connective Tissue Carbohydrates and
Polysaccharides and the Putrefaction of Lipoprotein and Protein Mucus waste Toxemia;

2.) Systemic Vascular (blood vessel) Membrane Placque (as opposed to Oral Food Plaque) Deformations;

3.) Systemic Respiratory Tract and Alimentary Tract Mucous Membrane Infections and Deterioration;

4.) Toxic Necrosis of Digestive Organs (liver, gall bladder, pancreas, appendix) and Vascular Organs
(heart, spleen, bone marrow, kidneys and bladder);

5.) Deterioration of brain and nerve system from toxic chemical imbalances and resulting
increased risk of depression, schizophrenia and bi-polar mental illness susceptibility;

6.) Increase in the quantity of Adipose (Fat) Tissue and its storage of toxic elements;

7.) Suppression of Liver made hormones, vitamins and other biochemical products and their deficiencies;

8.) Suppression of intestinal and vascular cellular made hormones, vitamins and other biochemical
products and their deficiencies; and

9.) Systemic Mutagenic and Carcinogenic Generation.

The sickness treatment epistemological answer to this question is staring the allopathic medical
sciences in the “special interest eye” and for over 50 years of suppression it has tried not to “blink.”
Ironically, allopathic medicine has been successful in organ transplanting by learning how to
“artificially suppress” with synthetic biochemicals the organ recipient’s body immune system from
immune rejection of the donor (foreign) biological human tissue. So allopathic medicine is trying to
use this same pharmaceutical control approach with the whole spectrum of anti-cholesterol drugs
but clearly have failed as the heart diseases have not been significantly reduced beyond the effect of
the growing vegan/vegetarian conversions yearly.

Specifically, since the May, 2002 Makishima’s Science Magazine, May 17, 2002 "Vitamin D Receptor
as an Intestinal Bile Acid Sensor" allopathic medical complex has been trying to use antibiotic control
of the gut pathological anaerobic bacteria that produces the carcinogen Lithocholic Acid (LCA) from
Dietary Cholesterol. But the human body genome will refuse as it has for over 800,000 years to
accept the novel Omnivore Diet as natural; responding to domesticated mammalian flesh and organs
as a form of “mammal cannibalism” eating from one’s own mammal family group being toxic for the
homo sapien species. This modern civilization mistake is the foundation of the etiology of the Dietary
Cholesterol and Related Diseases and Syndrome.

"My dream is that people will come to view eating an animal as cannibalism."
Henry Spira (1927-98)

Specifically, the Human Body Blood Stream alkalinity (basic pH) and sanitary status free of food waste
being fed on by pathogenic microbes is the foundation of mental and physical health and long life free of
disease and dysfunctional syndromes. The DCRDS Systems Analysis Body Flow Chart identifies the
following contaminants and dysfunctions of the Human Body Blood Stream:

1.) Lithocholic Acid (LCA) ____ most powerful biological Carcinogen known to science.
(Bile Acid metabolism) ___ bile acid metabolism involving Dietary Cholesterol and
facultative anaerobic E. Coli and obligate anaerobic Clostridium,
Bacteriodes, Eubacteria and Vellonella bacteria leading other
pathogenic anaerobic bacterial putrefaction of Lipoproteins
and the Primary Bile Acids.

2.) Free Radicals ___________ most powerful cell membrane destructors known to science
(Bile Acid metabolism) opening cells to microbial infection and serum toxins.
____ bile acid metabolism involving Dietary Cholesterol
and anaerobic bacterial putrefaction.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 27

3.) Acid pH ________________ supports pathogenic microorganisms to grow


(Protein metabolism) resulting in Fermentation of muco-polysaccharides
based connective tissue producing gas and acid blood.
____ supports Carcinogenic reactions.

4.) Low Oxygen (O2) ________ supports anaerobic microbial Putrefaction (decay) of fats
Content and proteins.
(Bile Acid Metabolism) ___ supports Carcinogenic reactions.
___ supports Free Radical formation.

5.) High Urea Content ________ supports Heliocobactor Pylori colonization in Stomach and
(Protein Metabolism) Small Intestine's Duodenum transforming the urea into
a gastric acid buffer with increased ulcer and cancer risk
for these digestion organs.
____ contributes to Diabetes Mellitus- Adolescent onset Type I.
____ contributes to Kidney/Renal failure.

6.) High Uric Acid ___________ contributes to acid pH Blood.


Content ____ Carcinogenic.
(DNA/RNA, ____ contributes to Kidney/Renal failure and death there from.
Neuro-Protein Metabolism)

7.) Mucus Waste ___________ undigested Chylomicron and


(Lipoprotein Chylomicron Remnants composed of Dietary Cholesterol
Metabolism) and associated Animal Protein and Animal Fat residues
____ contributes to acid PH of blood.

Please note that exogenous “mucus” waste from partially and undigested animal “pseudo” and cooked
foods are confused in medical literature and observation with endogenous “mucous” secretions by
mucosal skin, intestinal, respiratory and connective tissue cells. These homonyms reflect the confusion
that reigns in understanding the “great ramifications of Dietary Cholesterol and bile acid metabolism.”

Referring to Appendixe J the culmination of these “ramifications is that the life stream of the Human
Body's cells the Blood Stream becomes polluted from the intestinal anaerobic pathogenic bacterial
enteric cesspool unsanitary conditions where the normal alkalinity (basic pH) of the blood
becomes acidic producing the most powerful biologic carcinogenic known to science Lithocholic Acid
(LCA) and its associated toxic Free Radicals. Consequently, allopathic medicine is hard pressed to
explain the etiology and to control the TKD #13 Hypertension (HTN, High Blood Pressure) as reflected
in its descriptive classification as follows:

1.) where 95% of the incidence is termed Essential HTN or “Idiopathogenic” HTN because it is of
unknown cause; and

Note: The black American has a 4 fold higher incidence than the white American with their disease course progressing
faster, more severe with a higher death rate.

2.) where 5% of the incidence is termed Nonessential HTN (Secondary) with known etiology
including endocrine gland diseases, kidney diseases and tumors (benign and cancerous).

It is hereby declared that the cause of 95% of Hypertension in America called Essential
(Idiopathogenic) HTN is Chronic “Nutritional Acidosis” whether from “metabolic acidosis” (from
increased nutritional acid metabolites) and/or “kidney acidosis” (from the kidney’s failure to excrete all
the blood nutritional acid metabolites into the urine) and the blood pH falls below 7.3. This chronic
acidic pH blood condition that all omnivore dieters suffer by definition develops largely from the
i.) “great ramifications of Dietary Cholesterol and bile acid metabolism;” ii.) animal protein
metabolism; iii.) animal fatty acid metabolism and iv.) the anaerobic pathogenic bacteria toxemic
condition of the large intestines producing the following toxins and acids in the human blood stream:

a.) free primary and secondary Bile Acids (CA, CDA, DCA and LCA);

b.) Uric Acid;

c.) Urea (neutral pH in water but when utilized by the pathogenic bacteria Helicobacter pylori in the
stomach which turns it into a buffer an acidic residue is a byproduct);

d.) free dietary Fatty acids; and

e.) free amino acid residues from dietary protein oxidative degeneration.

The aboriginal vegan genome genotype human body in Chronic “Nutritional Acidosis” increases
blood volume automatically diluting the blood with the addition of water raising the pH and simultaneously
increasing blood pressure.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 28

I. Great Britain's Prince of Wales Prince Charles Warning to Abu Dhabi,


United Arab Emiratis about Diabetes Mellitus

Modern allopathic medicine has identified no definitive cause for Diabetes Mellitus and at best consider
it an auto-immune disease but do not understand the etiology of this Metabolic disease phenomena.
This was seen in the 2008 National Institutes of Health (NIH) Low Blood Sugar National Field Tests
being called off because of a significant number of elder deaths that resulted.

Ironically, in February, 2007 the Great Britain Duke of Wales Prince Charles had already gone on record
in a speech in the Abu Dhabi capital of the United Arab Emiratis of which has the dubious distinction of
having the highest Type 1 (Juvenile) and Type 2 (Adult) Diabetes Mellitus incidence and death rates in
the world explaining the etiology. Prince Charles warned the Abu Dhabi government and its people to
avoid eating at the American imported MacDonald's Restaurants if they wanted to stop this "fast food"
caused nutritionally related plague. American medical authorities, MacDonald's Restaurant
spokespersons and American press were incredulous and mystified by Prince Charles's layman
etiological warning.

Yet it is clear upon research document synthesis based simulation of the Dietary Cholesterol and
Related Disease and Syndrome DCRDS Systems Analysis Body Flow Chart that Diabetes
Mellitus is a result of ingesting Animal/Dietary Cholesterol and its related Animal Protein and
Animal Fat residues that are the hallmark of American fast food restaurant's high protein and high fat
menu and is a DCRDS member.

A recent definitive study from Japan called the Hisayama Study published as the article by Matsuzaki,
T, et al, “Insulin Resistance is associated with the pathology of Alzheimer’s disease,” August 25,
2010 rendering of the Journal of Neurology-Online (American Academy of Neurology) has
confirmed an association between the formation of Neurotic Placques of Alzheimer’s Disease and
occurrence of Diabetes Mellitus Type II suspected since the 1980’s. This is not surprising since these
two syndromes are both considered by the allopathic medical sciences as auto-immune diseases.

According to our paradigm they are members of the Animal/Dietary Cholesterol, and Related Diseases
and Syndromes (DCRDS) as the result of ingesting Animal Dietary Cholesterol, Bile Acid, DNA,
Protein and Fat eliciting a holistic body antigen production and inflammatory immune reaction as
autoimmune syndromes as follows:

a.) Diabetes mellitus Type I _ daily killing by clone white blood cells of Pancreatic beta cells
resulting in little or no insulin production;

b.) Diabetes mellitus Type II _ daily damage by clone white blood cells of Pancreatic beta
cells resulting in small to moderate amounts of insulin; and

c.) Alzheimer’s Disease _ 1.) clone white blood cells deposit amyloid beta protein resulting
in Neuritic Placques between brain neuron cells; and, 2.) brain neuron cells which produce
Neural Fibrilary Tangles within its cytoplasm composed of the cytoskeleton microtubule
associated Tau protein conjugated with dietary inorganic aluminum from commercial table
salt which is derived from an aluminum by-product of bauxite refining that is sprayed on rock
salt to keep it from sticking.

Dr. Neal D. Barnard. MD. has done like Dr. Dean Ornish, MD. has done with cardiovascular disease and has
scientifically documented that the Vegan Diet will reverse Diabetes Mellitus and the associated symptoms of
Metabolic Syndrome presented in his Program for Reversing Diabetes: The Scientifically Proven System for
Reversing Diabetes without Drugs (2008).

V. The Human Body is Genome Genotype Vegan/Herbivore: Ramifications of Dietary


Cholesterol Down Regulation of the Liver

A. Overview of Scope and Impact

Because the human body is genome genotype vegan/herbivore despite the blood type the
daily unnatural ingestion of Dietary Cholesterol daily causes the human liver to “down regulate”
or fail to synthesize as much as 1/3 its normal amount of de nova or Endogenous
Cholesterol. This was definitively demonstrated by the Peter JH Jones, et al, “Dietary
Cholesterol Feeding Suppresses Human Cholesterol Synthesis Measured by Deuterium
Incorporation and Urinary Mevalonic Acid Levels” article in the Journal of
Arteriosclerosis,Thrombosis and Vascular Biology (American Heart Association) V 16, pp
1222-28, 1996. This article’s Table 2 with data summarized and extrapolated noting that Mevalonic
Acid is a precursor of the human liver made Endogenous Cholesterol shown below:
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 29

Endogenous Cholesterol FSR’s & Daily Mevalonic Acid Excretion of Subjects Consuming Diets
Differing in Dietary Cholesterol: (Jones Table 2)

Dietary Cholesterol Level


_______________________________________________________________________________
Low Medium High Low Medium High
FSR’s (50 mg) (350 mg) (650 mg) Mevalonic Acid Excretion micro-mol/d
Pools/d _______________________________________________________________________________
Hypo Total Total
Group (7) % %
Mean 0.0711 0.0585 0.0483 2.325 2.021 1.944
+SEM + 0.0153 + 0.0101 + 0.0070 + 0.139 + 0.123 + 0.192

% of 17% 17.4% 34.4% 13.1% 3.8% 16.9%


Down
Reg.
__________________________________________________________________________
Norm Total Total
Group (12) % %
Mean 0.0756 0.0659 0.0634 2.476 2.069 1.829
+SEM + 0.095 + 0.006 + 0.0104 + 0.280 + 0.222 + 0.189

% of 12.8% 3.8% 16.6% 16.4% 12.6% 29.0%


Down
Reg.
_________________________________________________________________________________
Hyper Total Total
Group (11) % %
Mean 0.0628 0.0507 0.0481 1.881 1.979 1.573
+SEM + 0.084 + 0.082 + 0.082 + 0.118 + 0.272 + 0.191

% of 11.7% 5.1% 16.8% [5.2%] 20.5% 15.3%


Down Up Reg.
Reg.

Again, normally about half of the Endogenous Cholesterol made by the human liver and small
intestinal cells is used for providing cell membrane cholesterol throughout the body composed of
polysaccharides and fatty acids with Endogenous Cholesterol itself a crucial component.

Again, normally about the other half of the Endogenous Cholesterol made by the human liver and
small intestinal cells is in turn synthesized by the liver into 4 precursor categories of vital human
steroid body products as follows:

1.) for making Vitamin D3 by the human skin with proper solar UVB radiation.

2.) for making Adrenocortisone hormones the glucocorticoids by the Adrenal Glands that help
control the body’s glucose metabolism and immune system response;

3.) for making the Adrenocortisone hormones the mineralocorticoids by the Adrenal Glands
that help control the body’s water and electrolyte balance; and

4.) for making Estrogen (female) and male Androgen (male) sex hormones by the respective
sex's ovaries or testicles and to lesser extent by the Adrenal Gland’s cortex portion.

Thus it is quite reasonable to assume that from the ramifications of any given specific human daily
ingestion of Dietary Cholesterol that specific human’s liver is down regulating its normal Endogenous
Cholesterol syntheses and there will be an equal corresponding down regulation of its cell membrane
cholesterol and these 4 precursor categories of vital human steroid body products each by as much
as 30%!

B. Membrane Cholesterol Depletion

Indeed, the research literature identifies a number of Membrane Cholesterol Depletion associated
problems. Many are attributed to the Statin prescription drugs prescribed by Cardiologist Physicians for
cardiovascular heart patients which target the cholesterol biosynthesis enzyme HMG-CoA
reductase which is found in cell Endoplasmic reticulum membrane walls and Mitochondrion
membrane walls. But in many such cases the Statin drug caused Membrane Cholesterol depletions
are etiologically indistinguishable from liver down regulation by Dietary Cholesterol where the requisite
cholesterol rich lipid rafts are depleted because of a shortage of de novo Endogenous Cholesterol
synthesis as follows:
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 30

1.) SNARE (protein) processes;

2.) Vesicle associated membrane protein (VAMP) processes;

3.) Exocytosis (process where contents of a cell vacuole are released to the exterior of a
cell by fusion of the vacuole membrane with the cell membrane)

a,) loss of pancreas insulin producing Beta Cells exocytosis capability and thus insulin
suppression

b.) decreased exocytosis of Agrin and LRP4 secretions at neuromuscular junctions with
neuromuscular junction disease symptoms similar to Myasthenia Gravis

c.) Invasive skin infections from loss of exocytotic excretions of Apolipoprotein B and its
Immunosuppresions

d.) failure of Cholesterol/Apo E/LDL supply for exocytosis of myelination by


oligodendnocytes and Schwann cells impairs neuron maintenance leading to dementia
through neuron loss such as in Alzheimer’s Disease

4.) Endocytosis (process where cells absorb molecules like proteins from outside the cell by
engulfing it with their cell membrane)

a.) depletion of liver CoQ10 levels

b.) dysfunctional neurological and synaptic secretions

5.) Ion Channels

6.) Cytoskeleton Membrane Cholesterol Depletion activates Stress Fibers (actin fibers)

7.) link between membrane cholesterol depletion and adverse cognitive and behavioral
Problems

Membrane Cholesterol Depletion is overlooked yet is one of the "great pathophysiological


ramifications of dietary cholesterol and bile acid metabolism."

C. Vitamin D3 Deficiency

In 1980 the association of Vitamin D3 with the incidence of colon cancer was identified by the
epidemiologist Frank C. Garland and his physician brother Cedric Garland in the brilliant article
"Do sunlight and Vitamin D reduce the likelihood of colon cancer?", International Journal of
Epidemiology, V. 9, pg. 277-231. The Garland Brothers had noticed in 1974 from US county colon
cancer incidence data that colon cancer incidences were significantly higher in northern counties in
America compared to southern counties closer to the equator and having more sunlight. They surmised
that more solar radiation and subsequent skin photosynthetic Vitamin D3 production in the southern
counties was the preventive factor in this comparative difference.

In July, 2009 Cedric Garland, MD, PhD. and his research team including his brother Frank Garland
at Moores Cancer Center, University of California in San Diego, CA. in the Annals of
Epidemiology, “Symposium on the Epidemiology of Vitamin D and Cancer, April, 2009”,
presented their hypothesis of cancer etiology model. Their model identifies the loss of cellular
adhesion as the first step in cancer development and not a DNA gene mutation. Dubbed the
DINOMIT model where “D” refers to disjunction, or loss of communication between cells; it is felt
this model is weak because of the predicted ignoring of the “ramifications of ingestion Dietary
Cholesterol and bile acid metabolism.”

Unfortunately, the August, 2010 tragic death of epidemiologist Frank Garland, PhD. from
esophageal junction cancer within 12 months of diagnosis brings attention to the fact that Vitamin D2
supplemental ingestion which he advocated and followed does not suffice for the endogenous
photosynthetic skin production of Vitamin D3 in the prevention of cancer. It is interpreted herein that this
is a manifestation that the unnatural ingestion of Dietary Cholesterol which down regulates the human
liver’s synthesis of Endogenous Cholesterol by yielding a deficient production of Endogenous
Vitamin D3 by as much as 33% can not be overcome by Vitamin D2 Supplementation alone if at all.

Vitamin D3 deficiency is implicated in the following chronic diseases and syndromes:

1.) Metabolic Syndrome

2.) diabetes mellitus

3.) heart disease


THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 31

4.) cancer

a.) colon
b.) breast
c.) kidney
d.) pancreatic
e.) ovarian
f.) prostate
g.) liver
h.) dermal/skin

5.) osteoporosis

6.) stroke

7.) hypertension (increases the enzyme rennin synthesis by kidneys)

8.) Alzheimer’s Disease

9.) Parkinson’s Disease

Specifically, Cedric Garland, MD, PhD not acknowledging the ramification of bile acid metabolic
mutagenic and carcinogenic derivatives from the ingestion of Dietary Cholesterol in his
hypothetical DINOMIT model of cancer etiology results in it identifying the loss of cellular adhesion as
the first step in cancer development and not a DNA mutation renders this model as incomplete.

After 30 years of the Garland Brother’s ground breaking research Endogenous Vitamin D3 Deficiency is
being clinically and epidemiologically observed associated with cancer and other chronic diseases and
syndromes. But manifestation of Endogenous Vitamin D3 Deficiency as the most significant of the "great
pathophysiological ramifications of dietary cholesterol and bile acid metabolism" from liver down
regulation by Dietary Cholesterol is being prevention of sickness ignored with catastrophic results
reflected by the premature death of the brilliant epidemiologist Frank C. Garland, PhD.

D. Glucocorticoid Hormone Deficiancy

Glucocorticoid hormones in a human are steroid hormones produced by the adrenal cortex glands
from Endogenous Cholesterol made by that person’s liver. Their role in the body include:

1.) regulation of the metabolism of glucose;

2.) suppression of the immune response in the body by up-regulation of


anti-inflammatory proteins in the cell nucleus (transactivation);

3.) repress the immune response in the body by limiting the expression of
pro-inflammatory proteins in the cell’s cytoplasm (protoplasm) by blocking
movement of other transcription factors from the cytosol into the cell nucleus
(transrepression); and

4.) interference in the abnormal functions of cancer cells.

Cortisol (Hydrocortosone)

Cortisol (Hydrocortosone) made in the outer adrenal cortex is the most important for humans and is
essential for human life being released upon stress and low levels of blood glucocorticoids. Its
secretion is controlled by the hypothalamus gland which secretes corticotrophin-releasing hormone
(CRH). CRH triggers the pituitary gland secretion of adrenocorticotropic hormone (ACTH) carried via
the blood to the adrenal cortex gland]. Its effects are expansive including cardiovascular, homeostatic as
well as metabolic and immunological functions as follows:

1.) increases blood sugar through stimulation of gluconeogenesis (hyperglycemia-causing hepatic


breakdown of protein and fat to provide metabolites for glucose conversion in the liver);

2.) counteracts insulin by inhibiting the peripheral utilization of glucose (insulin resistence) by
decreasing transporters (GLUT4) to the cell membrane;
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 32

3.) immune system suppression by “muting” the white blood cells (T-cells) preventing the release of
inflammatory substances;

4.) aids in fat, protein and carbohydrate metabolism;

5.) decreases bone formation;

6.) activates anti-stress pathway when released restoring homeostasis;

7.) activates anti-inflammatory pathways reducing histamine secretion and stabilizing lysosomal
membranes preventing their rupture;

8.) stimulates hepatic detoxification by inducing tryptophan oxygenase (reducing serotonin levels in
the brain), inducing glutamine synthase (reducing glutamate and ammonia levels in the brain); and

9.) in the 30-32 week fetus initiates production of lung surfactant to promote lung maturation.

Many diseases treated with synthetic glucocorticiods are suspected of being caused by a specific
patient having an overactive Immune system. However, esoterically many are caused by the down
regulation of that person’s liver making Endogenous Cholesterol from a deleterious level of Dietary
Cholesterol; including:

a.) asthma;

b.) allergies;

c.) autoimmune diseases including

1.) diabetes mellitus


2.) pernicious anemia
3.) multiple sclerosis
4.) lupis

d.) septicemia

Ironically, it should also be noted that highly potent synthetic glucocorticoids are being used to
suppress the human body’s immune system to allow organs, limbs and other tissues to be
“successfully” transplanted by muting the rejection reaction of the body. The irony resides in
those cases where Dietary Cholesterol is the deleterious antigenic source of the need to replace
autoimmune damaged body parts and Glucocorticoid Hormones Deficiency is the secondary
factor in the failure to suppress the body’s antibody and inflammatory reactions.

Glucocorticoid Hormones Deficiency is grossly overlooked clinically yet is one of the "great
pathophysiological ramifications of dietary cholesterol and bile acid metabolism."

E. Mineralocorticoid Hormone Deficiancy

Mineralocorticoid hormones in an individual human are steroid produced by the adrenal cortex
glands from Endogenous Cholesterol made by that person’s liver. Their role in the body include:

1.) water balance in the body; and

2.) electrolyte (salt) including Sodium (NA+) and Potassium (K+) balance in the body.

Aldosterone

Aldosterone is a steroid hormone that affects the kidney by increasing blood volume and therefore
increases blood pressure. It is yellow in color and produced by the adrenal cotex gland. It specifically
acts on the distal tubules and collecting ducts of the kidney’s functional unit called the nepron
causing it to increase ion reabsorption and water in the kidney:
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 33

i.) conserve sodium (Na+);

ii.) secrete potassium (K+);

iii.) increase water retention; and

iv.) increase blood pressure.

Aldosterone is implicated in the etiology of Secondary Hypertension which represents only 5% of high
blood pressure incidences. The etiology of Primary Hypertension remains unknown.

Note that blood acidosis will normally result in the increased synthesis of Aldosterone and thus
increased blood volume; i.e. acid blood conditions is associated with increased blood volume.

Additionally ironically, there does not appear to be in clinical ramifications from a deficiency of
Mineralcorticoids from Dietary Cholesterol down regulation of the Liver; i.e. there is no significant
clinical low blood pressure incidences.

F1. Male Hormone Deficiency in the Male : Male Menopause (“Manopause”)

Male hormone deficiency or hypogonadism stems from a deficiency in the male sex hormone
testesterone from a decline in the production by the gonads/testicles which also produce estradilo,
antimullerian hormone, progesterone, inhibin B and actiin as well as sperm. The resulting “male
menopause” is also in the aged male called Late-Onset Hypogonadism (LOH).

Male Physical Symptoms may include not all of the following:

* High serum Dietetic Cholesterol


* High serum dietary lipoproteins
* Erectile Dysfunction (ED) Note: 50% of males over age 50
* Shrinking of the testicles
* Decrease in testicle firmness
* Increasing abdominal fat Note: associated with Metabolic Syndrome
* Glucose intolerance (pre-diabetes)
* Loss of bone mass (osteoporosis)
* Fatigue
* Muscle loss
* Heart disease (+)
* Decrease in growth of, or loss of, beard and body hair
* Hot flashes
* Gynecomastia (excessive development of male breasts)
* Frequent urination (polyuria) without infection/waking at night to urinate
* Achy muscles
* Liquid stools
* Night sweat
* Dry skin and/or cracking nails

Male Mental and Emotional Symptoms may include not all of the following:

* Low sexual desire/anger


* Shyness
* Depression
* Anxiety
* Psychological and relationship problems
* Difficulty concentrating
* Memory loss _ difficulty choosing words in language
* Poor sleep
* Irritability/Aggressiveness
* Infertility
* Loss of or nonexistent sense of smell (+)

The implications of the unnatural ingestion of Dietary Cholesterol and its down regulation of the
human liver by as much as 33% from making Endogenous Cholesterol and thus a proportional
deficiency in male hormone production by the male gonads is significant looking at the possible
symptoms.
____________________________________________________________________________________________

Footnote: (+) __ homologiously exists in female condition not observed in male but should be present.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 34

F2. Female Hormone Deficiency in the Female : “Early Onset Menopause”

Female hormone deficiency or hypogonadism stems from a deficiency in the female sex hormone
estrogen from a decline in the production by the gonads/ovaries which also produce progesterone as
well as store, maintain and normally release monthly the egg(s) into the Fallopian Tube. The resulting
“female menopause” is by conventional medical science in the pre-50 year old aged female called
Early-Onset Hypogonadism (LOH) or “menopause” or other wise menopause.

Female Physical Symptoms may include not all of the following:

* High serum Dietetic Cholesterol (-)


* High serum dietary lipoproteins (-)
* Loss of, or failure to develop, menstruation

Note: Esoterically not to be confused with the vegan or vegetarian girl or


woman becoming amenses (natural loss of menstruation from
extended alkaline blood from abstinence from eating acid forming
animal meat).

* Increasing abdominal fat (-)

Note: associated with Metabolic Syndrome

* Glucose intolerance (pre-diabetes) (-)


* Loss of bone mass (osteoporosis)
* Shrinking breasts
* Heart disease (+)
* Fatigue (-)
* Muscle loss (-)
* Loss of body hair
* Hot flashes
* Urinary bladder discomfort like frequency, urgency, frequent bladder infections
* vaginal lack of lubrication and vagina discharge
* Achy muscles (-)
* Liquid stools (-)
* Night sweats (-)
* Dry skin and/or cracking nails (-)
* Loss of or nonexistent sense of smell (+)

Female Mental and Emotional Symptoms include not all of the following:

* Low sexual desire/anger/irritability


* Shyness (-)
* Depression (-)
* Anxiety (-)
* Psychological and relationship problems
* Difficulty concentrating (-)
* Memory loss _ difficulty choosing words in language (-)
* Sleep disturbance
* Infertility

The implications of unnatural ingestion of Dietary Cholesterol and its down regulation of the human
liver by as much as 33% from making Endogenous Cholesterol and thus a proportional deficiency in
female hormone production by the female gonads is significant looking at the possible symptoms.
______________________________________________________________________________

Footnote: (-) __ homologiously exists in male condition not observed in female but should be present.
(+) __ homologiously exists in female condition not observed in male but should be present.

Please note that the specific unnatural ingestion of Dietary Cholesterol resulting in a mandatory
down regulation of the human liver is not an option but a reality and the resulting deficiency in
Endogenous Cholesterol and the subsequent deficiency in the hormones made by the skin
keratinoctes (Vitamin D3), the adrenal cortex (glucocorticoids and mineralocoticoids) and the
male testicles (testosterone) and female ovaries (estrogen) constitutes a significant deleterious
health risk not found in any benefit of unnatural animal meat and rennit dairy product ingestion!
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 35

VI. Helicobacter Pylori Pathogen: First Formally Recognized (UN/WHO) Bacterial


Carcinogen and Gastro-Intestinal Pathogen
A. Bacterium Exploits the Animal Meat Ingesting Stomach with “Design from Hell”

The foundation of this e-Book The Purple Seal rests upon a 30 year analysis and synthesis of “state
of the art” human health sciences research, development and demonstration (RD & D)
documents. Thus it has already been shown that the international leaders in the generic health
sciences past and present corroborate the legitimacy of the The Great Law of Aboriginal
Human Vegan Diet as not ancient fiction but ancient perennial preventive sickness
knowledge. Prophet Moses expressed it in his “aboriginal vegan/herbivore diet directive” in the
Bible Genesis 1: 29 reflecting the reality the aboriginal human body is genome vegan/herbivore
genotyped. The mitochondria cell organelle with its own DNA maintains this!

The Biblically cited Mystery “School of On (Annu or God)” of Ancient Egypt/Kemit taught this basic human life
vegan nutritional premise not only to its student Prophet Moses (esoterically alias Pharaoh Akhenaten) but to
other famous students like Ancient Egyptians/Kemitians Vizier Imhotep (Father of Sickness Prevention and
Cure, Greek God of Healing), Pharaoh Khufu/Cheops (Giza Great Pyramid renovation), Pharaoh Menkaure
(Giza Second Pyramid), Pharaoh Amenemhet II (Labyrinth Mortuary Temple, Lake Moeris and Pyramid),
Pharaoh Thothmoses II (Giza HU/Sphinx Rock Sculpture sand clearance and renovation), Pharaoh-Queen
Hatshepsut (Thebes Amen-Re Temple Obelisk, Punt expedition); Ancient Greek Philosophers Solon,
Pythagoras, Plato, Socrates and Hippocrates; and Essene Hebrew Israelite Prophets Jeremiah, Daniel,
Samson, Samuel, John the Baptist, Jesus Christ and the Disciples of Jesus Christ the Apostles Mary
Magdalene, John, Matthew, Peter and James the Just (Christ’s brother).

Consequently, the 1983 “accidental” discovery of the then unknown Heliocobactor (H.) Pyori
bacteria and its subsequent identity as the cause of a lifelong horrendous infection of a majority
of the world’s humans is a sign. This discovery has lead to the identity of the H. Pylori bacteria
as one of the most successful pathogens on earth infecting over 50% of the planet’s humans.

This is a clear generic health science epistemological sign that the animal meat and dairy
product Dietary Cholesterol containing anthropologically novel Omnivore and Carnivore
Diets are in total opposition to The Great Law of Aboriginal Human Vegan Diet. This
should have been a “wake up call” to the recalcitrant to change allopathic medical sciences but
it has not been. The H. Pylor bacteria diabolically seizes upon every opportunity to further infect
its host resulting from the "great pathophysiological ramifications of dietary cholesterol and bile
acid metabolism" leading to more damage to the host.

In ironic fashion befitting violating The Great Law the H. Pylor bacteria pathogenically exploits
those human hosts who knowingly or unwittingly ingest unnatural “pseudo” food animal meat
and organs. The H. Pylor bacteria fiendishly and ingeniously devises a way to uniquely ingest
their human host’s HCl acid producing and protected flesh and incorporate it into their own
outer membrane in turn causing devastating autoimmune responses by the host’s confused
immune system weakening it further by attacking itself!

Micro-anaerobic (2% O2) Heliocobacter Pylori bacteria (Gram negative) utilizes its 2 to 6 flagella
and helix (spiral) body to move through its stomach mucus food waste niche (Wikipedia)

Wherein the Helicobacter (H.) Pylori bacterium does in the omnivore diet stomach the following:

1.) Fills the narrow niche in the less acidic unnatural sticky animal meat mucus food waste residue covering
of the stomach (gastric) lumen mucosa using it as its exclusive habitat where other bacteria are absent
because of the acidity of the Hydrogen Chloride (HCl) acid secretions of the gastric parietal cells. This
maintains the acid pH of the stomach lumen required by the pepsin digestive enzyme secreted by the
gastric zymogen cells to begin digestively breaking down ingested food proteins, sugars and fats.
Without this unnatural niche from the Omnivore Diet ingestion of animal flesh and dairy products there
would be no unnatural sticky animal meat mucus food waste residue covering the stomach (gastric)
lumen mucosa for the H. Pylori to be able to easily successfully infect humans as it does.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 36

Please note that the allopathic medical sciences are confused in not distinguishing the unnatural “mucus” from
old food waste residues from the natural “mucous” produced by the mucosa cells that protects and lubricates
the entire stomach (gastric) mucosa. “Mucus” and “mucous” are homonyms that have evolved from this
institutionalized ignorance meaning entirely different things as the former is an exogenous dietary “pseudo”
food derived waste and the latter the endogenous beneficial gastric cellular secretion.

2.) Uses its 2 to 6 flagella and helix shape to move around and drill through its less acidic and sticky animal meat
mucus food waste residue covering niche covering the inside (lumen) of the stomach (gastric) mucosa
which helps to shield it from the acidity of the stomach lumen.

3.) Uses its Urease Enzyme to transform by hydrolysis the stomach’s urea into an ammonia buffer that it uses to
neutralize the stomach’s HCl acid enabling it to infect and ingest human red blood cells and gastric cells.

(NH2)2CO + H2O CO2 + 2NH3


Urea + Water Carbon Dioxide + Ammonia

Structure of the Urease Enzyme gives the Heliocobactor Pylori bacterium its unique ability survive for
short periods of time in the stomach lumen’sHCl Acid environment by producing a Urea derived Buffer.

Ironically this excess stomach urea is derived from the dietary protein metabolism in the liver from animal
meat/dietary protein catabolism that then leaks back into the stomach from the blood stream because the
kidneys are unable to remove the excess urea. The H. Pylori bacterium misses no chance to better infect.

B. H. Pylori Diseased Esophageal, Stomach and Duodenal Etiologies

1.) Uniquely, the Heliocobactor pylori bacterium synthesizes 3 fatty acids as follows::

i.) 19-carbon cyclopropane fatty acid (19: O cyc) _____ 35% of its total fatty acids
ii.) 14-carbon tetradecanoic fatty acid (14: O) ________ 49% of its total fatty acids
iii.) 3-hydroxy octadecanoic fatty acid (3 OH: 18: O) ___ 14% of its total fatty ac

These 3 fatty acids have antisecretory (inhibitory) effects on the stomach parietal cells’
release of their production of HCl acid by:

1.) their blocking H+ and K+ ATPase; and


2.) their detergent effects.

Consequently, when a specific stomach parietal cell synthesizes HCl Acid it is stored in that cell but is
not properly secreted from the cell accumulating and causing its atropic death. Please note that this
antisecretory (inhibitory) effect on the stomach parietal cell production of HCL acid is the basis of
Atrophic Gastritis detailed further below.

Additionally, these 3 fatty acids have antisecretory (inhibitory) effect on the stomach parietal cell’s
production of Intrinsic Factor required for the body’s cells to absorb dietary and intrinsic Vitamin B-12
and thus involved in the auto-immune disease of pernicious anemia.

2.) Ironically, the Helicobacter pylori bacterium further exploits the unnatural Omnivore and Carnivore
diets of humans by synthesizing 6 cholesteryl glucoside isomers containing either Animal/Dietary
Cholesterol or Human Host Endogenous Cholesterol which it incorporates into its outer membrane
assisting its infection of the stomach respectively through chronic gastritis or atrophic gastritis.

a.) It synthesizes 3 isomers composed of ingested Animal/Dietary Cholesterol which cause antigen
inflammatory immune responses characterized by too much HCl acid production.

i.) Cholesteryl-6-O-Tetradecanoyl-Alpha-D-Glucopyranoside;
ii.) Cholesteryl Alpha-D-Glucopyranoside;
iii.) Cholesteryl-6-O-phosphatidyl Alpha-D Glucopyranoside;

1.) Significant etiological element in 30% incidence rate of dyspepsia (heart burn); and
2.) Results in 50% incidence rate of chronic gastritis in the esophagus, stomach and
duodenum.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 37

b.) It synthesizes 3 isomers composed of its Human Host’s Endogenous Cholesterol ingested by H. Pylori’s
scavenging infection with the killing via hemolysis of red blood cells producing the following isomers
which cause auto-immune reactions characterized by too little HCl acid production and gastric cells
changing their identity to avoid attack by the body’s immune system ___ intestinal metaplasia.

i.) Cholesteryl-6-O-Tetradecanoyl-Alpha-D-Glucopyranosides;
ii.) Cholesteryl Alpha-D-Glucopyranosides;
iii.) Cholesteryl-6-O-phosphatidyl Alpha-D Glucopyranosides; and

1.) Significant etiological element in the 50% incidence rate of atrophic gastritis; and
2.) Leads to intestinal metaplasia with gastric fibrosis and intestinal epithelium and can
cascade to gastric cancer.

Summarily causing general acute inflammation and acute gastritis that escalates to a chronic or atropic gastritis
from the body’s immune response to its infection of stomach (gastric) mucosa cells, the H. Pylori bacterium uses its
animal meat mucus waste residue covering niche to attack the gastric parietal cells. Their HCl Acid secretions
although causing H. Pylori the most resistance to its infection of the stomach (gastric) mucosa is neutralized with an
ammonia buffer made from excess urea from the Omnivore Diet.

Depending upon the severity of the H. Pylori bacterial infection the following deterioration of its human host can follow:

i.) gastric ulcers _ 10 to 20% of those infected


ii..) duodenal ulcers
iii.) gastric cancer _ 2% of those infected
iv.) esophageal cancer; and
v.) duodenal cancer.

With 50% of the world’s human population colonized by Helicobacter Pylori bacteria and inevitably
gastritis accompanying this infection the asymptomatic nature of this parasite and its still unsolved
human transmission vectors indicate that it should be eradicated in all cases where diagnosed
because of its exploitation of dietary cholesterol metabolism and its ingestion of human cells
scavenging Endogenous Cholesterol. Evidence that its liver colonizing Helicobacter hepaticus
bacterial relative is associated with liver cancer is indeed cause for alarm!!

C. Prevention and Eradication

Predictably, allopathic medicine as with the large intestinal toxemic anaerobic pathogenic bacterial
colonization is confused and divided about the Helicobacter pylori bacterial colonialization of the human
stomach approaching 80% of the human populations in non-industrialized countries and 50% of the people in
industrialized countries. This toleration of animal meat eaters being habitually bacterially infected is
manifested by H. Pylori’s “so-called” asymptomatic clinical nature although dyspepsia and/or chronic or
atrophic gastritis are inevitable consequences.

Thus predictably, the mode of human infection of the Helicobacter pylori is still “officially” a mystery,
although it can be cultured from the saliva, vomit and feces of humans. However, pregnancy to birth
infancy via the Mother’s womb is the obvious time of most human infection! Additionally, infancy
infection if not treated as a child, youth or adult is lifelong with dyspepsia, gastritis, ulcers and
cancer incidence certain as the omnivore and carnivore diets are risk factors.

Prevention strategies include the following:

1.) vegan diet;


2.) monthly high enemas using fresh garlic infusion in the water;
3.) monthly up to 9 day fasts with Mexican papaya;
4.) use of broccoli sprouts in salads which retard H. Pylori growth; and
5.) use of fresh garlic and cold pressed olive oil daily in salads.

Incredibly, allopathic medicine’s ignorance of "the great pathophysiological ramifications of dietary


cholesterol and bile acid metabolism" leads to a sickness prevention incompetence evidenced by a
confused state of toleration for dangerously pathogenic anaerobic bacteria as follows:

A. Life long Stomach Colonization Infection by Micro-anaerobic (2% O2) Heliocobacter Helicobacter Pylori Bacteria
of humans being seen somehow as beneficial; and if dyspepsia, gastritis, ulcers or cancer have not been discovered
somehow H. pylori infestation of humans is not a disease state; and

B. Life Long Colon/Ascending and Transverse Large Intestinal Colonization toxemic infection by several
anaerobic pathogenic bacteria predominately including Bacteroides, Enterobacteria and Clostridia in all
omnivore diet humans producing the secondary and tertiary Bile Acids which are mutagenic, carcinogenic,
atherogenic, lithocholegenic and cytotoxic is somehow ignored as a significant disease state!!
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 38

VII. The Implications for Caucasian Humans and for Other Omnivore Humans in the
Etiology and Prevention of Skin Cancer (or Melanoma)

Esoterically, opposition to the truth that there is but One Human Race or One Human Species
made up of various sub-races (breeds) or subspecies of Humans reflects the suppression of
the “great ramifications of the metabolism of Dietary Cholesterol and Bile Acids” by the
demonic “White Supremacists” who oppose the Great Law of the Vegan Human Diet and
coincidentally suppress how the Caucasian Peoples became “white” other than the myth of
being superior.

”The differences that exist between the major racial groups are such that races could be
called subspecies if we adopted for man a criterion suggested by Mayr (1963) for
systematic zoology.”

[Cavalli-Sforza, L.L. and W.F. Bodmer, The Genetics of Human Populations, (1977)]

“One of the biggest illusions and contradictions is ‘race’, which confounds people of all
colors and cultures. In particular it must be understood that culture not color is the
determinate factor in group dynamics in an ideal state of group consensus and action…
Cultural identity not skin color is the key. ‘Toleration for all …. For all are One’ is the rule.
…… That there is but ‘one race’ the human race is proven continuously by the mixture of
races and the human gene pool. Miscegenation results in offsprings being fully fertile. In
contrast the now extinct Tasmanian race was incapable of producing fertile offspring
upon race mixing with humans.”

[Quote by George W. Singleton August 15, 1990 [printed in The Egyptian Mystery
“School of On (God or Annu)”: Esoteric Atannuology, Egyptology and
Rastafariology, Vol. 1, 2005 page 39]

“You often hear people who have been conditioned by blending [miscegenation] saying
that ‘there is only one race, the human race.’ It's an absurd statement. There is no
human race. There is a human species. And then there are races, which are the
equivalent of breeds in dogs. Wouldn't you think it's absurd if someone said ‘there is
only one breed, the dog breed’?”

[BC Millard, Internet, 2007] (White Supremacist)

A. The Genetic Mutation Loss of the Prehistoric Caucasian Peoples’ Aboriginal Brown Skin Color

In 1922 the brilliant and courageous Caucasian German European nutritionist and physiologist Arnold
Ehret (1866-1922) declared the following “gigantic idea” in his iconoclastic nutritional herbology
classic book Mucusless Diet Healing System that the Caucasian people or sub-race's white skin
color is the manifestation of what is today designated an etiologically unexplained human genome
genetic mutation phenomena:

Arnold Ehret, circa 1914-15

"In my first published article I promulgated the ”gigantic idea” that the white race is an
unnatural, a sick, a pathological one.”

“First, the colored skin pigment is lacking, due to a lack of coloring mineral salts … second
the blood is continually over-filled by white blood corpuscles <and>”

"(Third) The skin pores of the white man are constipated by white dry mucus, his entire tissue
system is filled up and filled out with it…. waste with white color; thereafter the white
appearance of the entire body."
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 39

“No wonder he looks white and pale and anemic …. Everybody knows that an extreme case of
paleness is a 'bad sign’."

[from Arnold Ehret, Mucusless Diet Healing System, 1922, page 72, emphasis and
reformatting added]

Thus nearly 90 years ago Arnold Ehret was the first scientist to recognize and promulgate the
“gigantic idea” that the European Caucasian Peoples’ pale white skin color is an abnormal
phenomena associated with 3 elements of pathophysiology as follows:

1.) implied genetic lack of melanin the colored skin pigment;

2.) white blood cells over abundant in the blood stream__ whose white color is derived from
these cells’ phagocyte ingestion of the partially digested food waste called mucus; and

Note: The "white color" is from eating animal meat/dietary cholesterol as cholesterol in
its pure state is white in color reflecting the entire colored light electromagnetic
spectrum instead of absorbing part of it and reflecting the color spectrum for example
brown or yellow color.

3.) mucus waste composed of an unsanitary acidic pH residue from the ingestion of animal/
dietary cholesterol and other animal meat residues including animal/dietary DNA, animal/
dietary protein and animal/dietary fat from “pseudo foods” of animal derived body parts
and dairy products(milk, cheese and eggs) and to a lesser extent an unsanitary basic pH
residue from cooked plant foods.

Note: “Mucus” is not to be confused with the human connective tissue lubricant issuance
“mucous.”

The Caucasian German European nutritionist and physiologist Arnold Ehret was indeed courageous to
have deduced and promulgated his ”gigantic idea” because esoterically shortly after its republication
in 1922 the demonic “White Supremacist” forces including the Ku Klux Klan that controlled the White
House in America clandestinely carried out his murder to look like an “accident” on Olive Street in Los
Angeles, CA. as he “fell” on the street curb and crushed the back of his skull with no eye witnesses.

As early as 800,000 BC. the practice of “mammalian cannibalism” involving the invention of hunting
and eating of wild mammalian animals including other humanoids was in widespread practice in
Europe, the Mid-East and Asia from a survey of archeological studies of ancient homo sapiens and their
fecal remains. Appendixes A-1 and A-3 present detailed analysis of the esoteric metaphysics of the
novel and experimental Omnivore Diet and its technologically complementary invention animal
husbandry based agriculture by the Caucasian Peoples collectively comprising the Western
Civilization in Europe, Mid-East Asia and Asia. These biological inventions have origins in the current
Quaternary Ice Age beginning circa 3 M BC. and ongoing.

Please note that the following animal husbandry agricultural or farming invention elements were fully
developed by Western Civilization Caucasian Peoples circa 15,000 BC. to 10,000 B.C. in Europe:

1.) most of the domesticated grain plants of corn, wheat, rye, barley and oats via mono-crop farming;

2.) the domesticated animals of the horse, cow, pig, goat, sheep and chicken; and

3.) the dairy products of domesticated animal milk and cheese as a food staple.

These biological inventions allowed the Caucasian Peoples of Western Civilization to become
socially accepted, more civilized as humans and to be able to shun to extinction those homo sapiens
who continued to practice the socially ostracized practice of “mammalian cannibalism” of other
humanoids which a priori is evil and demonic. The Neanderthals were so shunned and had predictably
become extinct by circa 28,000 BC. hypothesized herein from human spongiform encephalopathy.

Please note in October, 2005 Keith Cheng, et al, in Science, V. 28, p. 601 announced that geneticists
studying the zebra fish by accident had identified the exact gene mutation SLC24A5 on the q (long)
arm of the human chromosome 15 (position 21.1 from base pair 64,200,461 to 46,221,881) that was
responsible for the prehistoric mutation in approximately 50,000 to 10,000 BC. causing the Caucasian
Peoples’ genome loss of their aboriginal brown skin color to white skin color. Their present white skin
color reflects a significant under producing of the human skin pigment Melanin.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 40

Using the General Human Systems Theory (GHST) paradigm generating Appendixes A-1 and A-3,
it is hereby declared that Arnold Ehret’s “gigantic idea” which he died trying to promulgate is
corroborated herein: That the catastrophic ramifications of the Caucasian Peoples’ breakage of the
Great Law of the Vegan Diet expressed in the Bible Genesis 1: 29 and their spreading the breakage of
the Great Law as normal have been historically and institutionally suppressed. Specifically, they
experimented initially with the invention of the Carnivorous Diet by eating exclusively cooked
domesticated animal meat and dairy product “pseudo foods” that resulted in their brown skin color
loss as Carnivores the “skin color mutation accident” circa 18,000 BC. The Caucasian Peoples’
then later adopted their related Asian Peoples’ invention of the Omnivorous Diet mixing cooked and
uncooked animal and dairy “pseudo” foods and plant derived foods which caused a different less severe
genetic skin color mutation. Please see Appendix A-3 for more details.

Caucasian Human Skin Cancer Melanoma Showing the Cancerous Melanocyte cells’ Chromosome
15 long arm genes SLC24A5 are now over producing the Melanin pigment. (Wikipedia)

The Epidermal/Skin Cancer of Melanoma that plagues the Caucasian Peoples involves cancerous
Melanocyte skin cells whose SLC24A5 genes are now appearing as over producing the Melanin
skin pigment is not coincidental; i.e. simultaneously UVB via proper human skin melanin can
produce Vitamin D3 and UVB via human skin melanin deficiency can cause DNA mutations and
if not repaired lesions.

Appendix A-3 presents the detail of this ”gigantic idea” hypothesis as to when, why and how this
European “Caucasian Skin Color Chromosome SLC24A5 Gene Mutation” took place. The conventional
explanation that temperate weather and reduced sunlight in the northern hemisphere climates was the
cause is clearly a secondary causation factor. Specifically, this conventional theory does not reflect the
knowledge of “the great ramifications of Dietary Cholesterol and Bile Acid metabolism” because of its
suppression as detailed above by the demonic “White Supremacists.” Thus hypothesized
is that the European “Caucasian Skin Color Chromosome SLC24A5 Gene Mutation” was not a
random genetic mutation but the result of their animal husbandry agriculture invention and
experimentation with Carnivore Diets; i.e. such Human unnatural diets are fast acting mutagenic,
carcinogenic and spongiform encephalopathogenic.

Consequently, the General Human Systems Theory (GHST) paradigm indicates that the now white
skin color European Caucasian Peoples’ adoption of the experimental Omnivore Diet and its
complementary invention of animal husbandry based agriculture as the core of Western Civilization
should after millenniums of breakage of the Great Law of Vegan Human Nutrition be observable. Such
“pathophysiological ramifications” amongst those Caucasian Peoples who have so exposed their
Vegan Diet programmed human genome chromosomes to the “slow poison” effects of the Omnivore
Diet. Accordingly appear above in the Section VI. Misconceptions of the Allopathic Medical Sciences
examples of these predicted pathophysiologies. The two syndromes of modern women __
menstruation and menopause are the most ubiquitous and ignored. Additionally, are the Caucasian
Peoples’ highest incidences of osteoporosis, gall bladder disease and low bone density of those
Peoples using the Omnivore Diet. This is directly related to the “slow poison” effects of Dietary
Cholesterol and its Related Animal Fat and Protein Residues. These of course are accepted as
normal by the allopathic medical sciences.

In summary, esoterically the European Caucasian Peoples suffered a catastrophic white skin color
mutation from their original brown color as the major ramification from breaking the Great Law of Vegan
Human Nutrition ingesting Animal/Dietary Cholesterol as Carnivores circa 50,000 to 10,000 BC.

B. The Etiology of Skin Cancer: DNA Nucleotide Bases & Pyrimidine Dimer DNA Mutations

Special significance must be given to the none coincidental “epidemiological flag” that the highest
cancer incidence type in humans of all types in the world __ 1 million incidences/year in America alone
___ is that of the 3 types of epidermal/skin cancers as follows:

1.) Basal Cell Carcinomas (BCC’s, 80%);

2.) Squamous Cell Carcinomas (SCC’s, 16%); and

3.) Melanocyte Carcinomas (Melanomas, 4%).


THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 41

Esoterically, again the Caucasian Peoples’ [white sub-species’] epidermal/skin cancer problems
are another ramification of the Omnivore diet and their earlier experimentation with the Carnivore
Diet leading to their prehistoric catastrophic “brown to white skin color mutation accident” as
they suffer more epidermal/skin cancer than all other human sub-races put together.

Both dark and white skin colored people will benefit from Arnold Ehret’s “gigantic idea” when
they understand its implications which he died courageously to promulgate to the world killed by
the demonic “White Supremacists.” The pathological epistemological understanding of the etiology
of epidermal/skin cancers will reveal much about the cause and prevention of all the other cancers.

The double helixes of the Deoxyribonucleic acid (DNA) molecule are connected by the specific dual
“Purine to Pyrimidine” bonding involving 4 Nucleotide Bases whose stereochemistry and bonding
options are as follows:

1.) Adenine (A) _ a Purine Nucleobase that bonds to the Pyrimidine Nucleobase Thymine (T).

Adenine (A)

Note a.: Purines are Hetero-Polycyclic Aromatics.

Note b.: Thus animal meat and dairy products provide Dietary DNA composed of
Dietary Adenine suspect of being strong mutagenic and carcinogenic.

2.) Guanine (G) _ a Purine Nucleobase that bonds to the Pyrimidine Nucleobase Cytosine (C).

Guanine (G)

Note a: Purines are Hetero-Polycyclic Aromatics.

Note b: Thus animal meat and dairy products provide Dietary DNA composed of
Dietary Guanine suspect of being strong mutagenic and carcinogenic.

3.) Thymine (T) _ a Pyrimidine Nucleobase that bonds to Purine Nucleobase Adenine (A).

Thymine (T)
Note a.: Pyrimidines are Monocyclic Aromatics.

Note b.: Thus animal meat and dairy products provide Dietary DNA composed of
Dietary Thymine suspect of being weak mutagenic and carcinogenic.

4.) Cytosine (C) _ a Pyrimidine Nucleobase that bonds to Purine Nucleobase Guanine (G).

Cytosine (C)

Note a.: Pyrimidines are Monocyclic Aromatics.

Note b.: Thus animal meat and dairy products provide Dietary DNA composed of
Dietary Cytosine suspect of being weak mutagenic and carcinogenic.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein
the Aboriginal Vegan Genotype Human Body” __________________________________ p 42

Again as part of this “gigantic idea” hypothesis is proposed that the following are not coincidences
but are elements of the complex etiology of epidermal/skin cancer which ironically appears to reverse
the European “Caucasian Skin Color Chromosome SLC24A5 Gene Mutation” in Melanoma cases:

a.) the highest type of cancer incidence in humans is that of epidermal/skin cancer; i.e. Basal Cell,
Squamous Cell and Melanocyte Carcinomas where the incidence of epidermal/skin cancer is
highest amongst Caucasians especially fairer white skinned members of Scandinavia Europe;

b.) the incidence of epidermal/skin cancer has a relationship with exposure to the Sun emitted Ultra Violet
(UV, with 100nm to 400 nm wavelength) portion of sunlight which produces cell DNA chromosomal
mutations where the incidence decreases with latitude or distance away from the earth’s equator
(zero degree latitude) where the sun shines the brightest and the longest;

c.) prolonged exposure to the Sun emitted Ultra Violet (UV) light __ UVA (> 320 nm), especially UVB (280
to 320 nm) and UVC (< 280 nm)__ may produce directly or indirectly several types of chromosome DNA
damage __ cell chromosomal DNA mutations including DNA lesions __ which if not repaired contribute
to the 3 types of epidermal/skin cancers BCC’s (80%), SCC’s (16%) and Melanomas (4%);

d.) the UVB (280 to 320 nm) range of sunlight photosynthetically produces in the human skin Vitamin D3
from human liver endogenous 7-hydroxycholesterol made from liver endogenous cholesterol AND
the UVB (280 to 320 nm) range of sunlight is the same sunlight spectrum producing the mutations
leading to the “signature” Pyrimidine lesions C to T and CC to TT including:

1.) Cyclobutane Pyrimidine Dimers (CPD’s) __ a direct photochemical reaction product constitutes
80% of human DNA lesions and is classified as a Pyrimidine Dimer DNA Mutation;

Cyclobutane Pyrimidine Dimer (CPD) [Generic]

2.) 6, 4 Pyrimidine – Pyrimidones (6,4 Photoproducts) __ a direct photochemical reaction product


constitutes 20% of the DNA lesions and is classified Pyrimidine Dimer DNA Mutation.

6, 4 Pyrimidine – Pyrimidones (6,4 Photoproducts) [Generic]

3.) DNA Single Strand Breaks (SSD’s)

4.) DNA Double Strand Breaks (DSB’s)

5.) Numerous Modified Nucleotide Bases

e.) the human skin pigment of melanin screens/blocks the harmful UV light and varies in its skin density
by so-called “race” factor (the darker colored the race the more melanin in their skin) and
environmental factors as diet, outdoor sun exposure and clothing.

f.) Endogenous 7-Dehydrocholesterol is the precursor of Endogenous Vitamin D3 and is produced by


the human liver from Endogenous Cholesterol and released into the blood stream. It is photosynthetic-
ally transformed in the skin by UV Sun Light into Vitamin D3 which is further activated in the kidney cells’
mitochondria or in the liver cells’ by their mitochondria or microsomes. Endogenous 7-
Dehydrocholesterol is of course not mutagenic and carcinogenic.

Endogenous 7-Dehydrocholesterol [the precursor of Endogenous Vitamin D3]


THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 43

g.) Animal Dietary 7-Dehydrocholesterol sourced from the ingestion of Animal “pseudo” food is as
expected mutagenic and carcinogenic as cited in Table III #5.

h.) Plant Dietary 7-Dehydrocholesterol sourced from the ingestion of plant derived food however
compared to g.) is not mutagenic and carcinogenic.

i.) Uric Acid is the metabolic detox by the human liver of Animal/Dietary DNA derived nucleotide Purine
bases Adenine (A) and Guanine (G) as animal derived DNA can not be incorporated into human DNA.
Uric Acid is mutagenic, carcinogenic, cytotoxic and cause of gout an especially painful form of
arthritis by those eating high red meat diets. The liver and kidneys prioritize the elimination of Uric Acid
and thus a major component in the body’s urine and sweat excretions is cited in Table III # 35.

Uric Acid

C. The Analogy and Lesson To Be Learned From the Origin of the Polar Bear

Analogously, it is further hypothesized that what happened to the Caucasian Peoples in the genetic
mutation loss of their aboriginal brown skin color from eating the novel Carnivore Diet in temperate
climates is what happened to the Omnivorous Diet eating Alaskan Grizzly (Kodiak species of Brown)
Bears that became trapped on ice sheets some 200,000 to 150,000 BC and adapted to eating an exclusive
Carnivorous Diet of baby seals. They mutated to today’s Polar Bears devoid of fur color but black skin.
As large as 1700 pounds Polar Bears along with the Kodiak Bear are the earth’s largest land carnivores.
The Polar Bears are the most carnivorous of all bears with the other bears being omnivores.

D. Prevention of Skin Cancer:: Inner Cleanliness and Natural Sun Tans

Arnold Ehret who first identified the Caucasian Peoples’ white skin color as a physiopathogenicity in
his 1922 classic nutritional herbology book Mucusless Diet Healing System; goes on and explains how
he reversed his own white color back to its original brown color and everyone thought he was a Native
American or Asian Indian via a “natural sun tan” regime. He achieved this by following his own
Mucusless Diet Healing System; i.e. a Herbivore/Vegan diet using foods that remove the undigested
animal residues he calls "mucus" that gives the white blood cells their characteristic white color from
their phagocytosis of Animal/Dietary Cholesterol in their “house cleaning” sanitary body maintenance
duties. Obviously carcinogenic tanning salons are unnecessary by those whites who utilize this solution.

E. Treatment of Skin Cancer:: Increase Endogenous Vitamin D Photosynthesis

From the above holistic analysis in any specific case of skin cancer it should be clear that the use of
chemotherapy, radiation and/or surgery are second best treatment modalities compared to the following
intervention regime implemented under medical supervision which would reduce the initial morbidity rate,
the death rate and reoccurrence morbidity rate of skin cancer regardless the race of the patient:

1.) vegan diet;

2.) internal body cleansing using 9 day monthly Mexican papaya fasts;

3.) internal body cleansing using high enemas/colonics;

4.) otherwise daily raw sunflower and pumpkin seed milk drinks; and

5.) otherwise daily freshly juiced carrot/spinach/beet/celery/garlic juice.

This biggest enigma of allopathic MD Dermatologists is why the same Ultra-Violet B Spectrum (UVB)
of sunlight simultaneously photosynthetically produces endogenous vitamin D3 in the human skin
and that same UVB sunlight spectrum can produce in that same human skin photosynthetic DNA
genetic damage lesions that if not repaired leads to dermal/skin cancers. This is one of the most
significant of “the great pathophysiological ramifications of dietary cholesterol and bile acids
metabolism” because the answer spans eons of time and is at the core of the errant “white
supremacy” dogma and the origin of the European Caucasian Race’s white skin color. It is of interest
to all races because of racial intermixing and the deleterious effects of the omnivore and carnivore
diets.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 44

The answer summarily is that the above interconversion reactions of Lathosterol to/from 7-
Dehydroxycholesterol or Pro-Vitamin D3 to/from Cholesterol are generic for all mammalian animals
and thus contained in their flesh. “Mammal Cannibalism” or Mammalian Animal Meat Ingestion by
vegan genome human beings violates the Great Law as expressed in the Bible Genesis 1:29. This
is the core reason for the above described Ultra-Violet B light mutagenic and carcinogenic
ramifications of ingesting Animal Lathosterol, Animal 7-Dehydroxycholesterol (Pro-Vitamin D3)
and Animal Cholesterol including:

1.) prehistoric Caucasian Peoples’ white skin color accident from Carnivore Diet melanin
DNA gene damage leaves their skin UVB unprotected from melanin deficiency; and

2.) every day Omnivore Diet ingestion associated epidermal/skin cancer incidence reoccurs
with the “ramification of Dietary Cholesterol and bile acid metabolism.”

VIII. Addressing the Genocidal Level of Infant and Maternal Mortality in America

In March and April, 2010, Amnesty International, Inc. and a United Nations sanctioned epidemiological
scholastic study identified the level of maternal and infant death rates in America as genocidal and
hard to explain given a.) the high level of per capita health care expenditures being spent; and b.) while
the rates over the past 10 years in most of the developing countries in the world have decreased the rates
in America have increased. Please see Appendices I-1 and I-2.

Esoterically as documented above and in Appendix A-1 the human genome was aboriginally
encoded genetically as herbivore/vegan. Thus the human liver of the fetus, neonate and infant
processes all Dietary Cholesterol from the Mother’s shared blood system and amniotic fluid without
exception as a “slow poison.” Using an allusive Third Bile Acid Biosynthesis Pathway (other than
the “Neutral” and “Acidic” Adult Pathways) a “unique mix of bile acids” inventoried below in TABLE V
are produced. This “unique mix of bile acids” pattern persists from human embryonic conception through
about the human infant’s 4th year of age being slowly transformed after birth by the development of a
pathogenic dominated intestinal flora from feeding upon solid animal meat food until the Omnivore
diet adult pattern of cholesterol and bile acid metabolism dominates.

It is very clear from research and development work under great public knowledge suppression
that unborn human babies in the womb are at risk from the immense co-mutagenic, co-carcinogenic,
atherogenic, lithogenic and toxogenic effects of Dietary Cholesterol and its over 25 Bile Acids and
other derivatives inventoried in TABLE III adversely affecting the fetus including its liver, heart, brain,
lungs, kidneys and pancreas. Especially pathogenic are the mono-hydroxy-bile acids; i.e. 3-beta-
hydroxy 5 cholenoic acid, Lithocholic acid (LCA, 3-alpha hydroxyl 5-beta cholenoate) and its
isomers Iso-LCA (3-beta hydroxyl 5-beta cholenoate) and allo-LCA (3-alpha hydroxyl 5-alpha
cholenoate).

Esoterically, the tradition of amenses women living upon the Vegan diet has been associated since
ancient times with painless and no-risk child birth. This is because the aboriginal Vegan diet produces
a sanitary maternal blood status and avoids the animal food derived mucus waste body deposits; the
latter which encumber the female pelvis preventing it as designed from disassembling and
allowing a natural pain free child birth.

Consequently, the Omnivore diet by necessity has been associated with Caesarian births since
ancient Rome and constitutes approximately 20% of America’s infant deliveries and encompasses the
bottom line of maternal mortality risk.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 45

Specifically, the “great pathophysiological ramifications of dietary cholesterol and bile acid
metabolism” is highlighted no better than in the suppression via ignoring the “repercussions of
Intrahepatic Cholestasis in Pregnancy (ICP) in “fetal complications” affecting the placenta and
fetal liver.

Quoting from the astute review article by Spanish scientists Jose G. Marin, et al entitled ”Molecular
basis of fetal bile acids and pigments through the fetal liver-placenta-maternal liver pathway”
published in the Journal of Hepatology, V. 4, No. 2, pages 70-76, 2005:

“The excretory pathway for COA’s [Cholephillic Organic Anions of bile acids and biliary
blood pigments] …….. is of great importance because when it is impaired [as in
cholestasis] the repercussions on the normal development of the fetus or even on the
fate of gestation may be dramatic.

Intrahepatic Cholestasis of Pregnancy [ICP] is a reversible form of cholestasis (stoppage


of bile flow) that may develop during late pregnancy and usually resolves soon after
delivery.

For the Mother, this condition is usually benign since it is only associated with certain
discomfort due to pruritis [itching].

However, ICP is frequently the cause of premature delivery and increased risk of fetal
mortality during the third trimester of pregnancy in patients suffering from this disease.

Moreover, the severity of fetal complications is proportional to the magnitude of


maternal hypercholanemia.” [emphasis added]

Appendix I-3 presents the ground breaking prospective study by Swedish scientist Anna Glantz, et al,
in the article “Intrahepatic Cholestasis of Pregnancy (ICP): Relationship between Bile Acid levels
and Fetal Complication Rates,” Journal of Hepatology, V. 40, No. 2, pp 467-74, 2004 details her
“state of the art” in vivo prospective cohort study of ICP. In this study ICP is defined as “otherwise
unexplained pruritis (itching) of pregnancy in combination with fasting serum bile acid level
greater than or equal to 10 micro-mol/liter.” Her study is the first to establish the relationship of
maternal serum bile acids and ICP.

The “fetal complications” from “Intrahepatic Cholestasis of Pregnancy (ICP)” are detailed in this
Swedish study as follows:

i.) spontaneous preterm deliveries,


ii.) asphyxial events; and

iii.) passage of meconium and its green staining of amniotic fluid, placenta and membranes.

Swedish scientist Anna Glantz further elucidates on ICP and its treatment from her “state of the
art” in vivo prospective cohort study conducted between 2/01/1999 and 1/31/2002 involving
45,485 pregnancies that identified 693 ICP diagnosed women where 81% had mild ICP (10-39
micro-mol/liter of serum bile acid) and 19% had severe ICP (serum bile acid greater or equal to
40 micro-mol/liter):

Simple logistic regression analysis showed that the probability of fetal complications
increased by 1 to 2% per additional micro-mol/liter of serum bile acids.

Complementary analysis showed that fetal complications did not arise until bile acid levels
were greater than or equal 40 micro-mol/liter.

Gallstone disease and a family history of ICP were significantly (P< .001) more prevalent in
the group of ICP patients with higher bile acid levels.

No increased fetal risk was detected in ICP patients with bile acid levels less than 40 micro- mol/liter.

Unfortunately, allopathic physicians are not trained that acid blood conditions which inevitably result
from the ingestion of animal “pseudo” foods can cause the symptoms of itching (purites) of the vagina and
anus of pregnant women.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body _____________________________________________________________________________________________________________ p 19-1
TABLE FOUR: Thirteen of the Top Fifteen Killing (TFK) Diseases Identified as Dietary Cholesterol and Related Diseases and Syndromes (DCRDS):
Comprehensive Results of the DCRDS Systems Analysis Body Flow Chart
Common Disease/Syndrome Name Dietary Cholesterol & Animal Lipoprotein Auto-Immune Disease/Syndrome Disease/Syndrome Conventional Holistic Vegan Diet
Implicated (L-P) LCA Bile Acid Implicated (C-B) Etiology Etiological Pathology Physiology Treatment Treatment Preventab
(Medical Science Name) Etiology Primary (P) Secondary (S) ] Element S- Surgical (xxx %)
[Primary (P) Secondary (S) C- Chemotherapy
R- Radiation
#1. DISEASES OF THE HEART 100%
a. Heart Attacks S P Vitamin D3 Triglyceride High LDL __ chemicals
(Myocardial Arrest/Infarction) Deficiency Esterified High VLDL __ surgery
From Dietary Low HDL
Dietary Cholesterol
Cholesterol in Blood serum High Homocystene
Acid Blood pH Low Blood O2
b. Congestive Heart Failure S P Vitamin D3 100%
Deficiency
From
Dietary
Cholesterol
c. Heart Block S P pace maker 100%
implant
#2. CANCERS Epithelial Cell Legally restricted Illegal 100%
[60% Obesity Associated Mutated Clones ___ Surgery
except Brain, Bladder, Skin) ___ Chemotherapy
___ Nuclear Radiation
a. Lung P S
Excluding
Tobacco Smoking
b. Stomach
1.) Heart Burn (Dyspepsia) (30%) P P High Gastric Acid Antiacids
1.) Ulcer S P Heliobactor High Serum Urea __ chemicals
Pylori Bacteria (20%) High Gastric Acid __ surgery
2.) Pernicious Anemia S P Parietal Cells killed Heliobactor Low Vitamin B-12 __ chemicals Probiotics
Intrinsic factor Pylori Bacteria __ supplements
3.) Gastric Cancer P S Heliobactor High Serum Urea
Pylori Bacteria High Gastric Acid
Neoplastic Tumors
High White Blood Cell
Animal Meat Ingestion
Response
c. Colorectal P S Vitamin D3 Triglyceride Lithocholic Bile Acid
Deficiency Esterified Coprostanol
from Dietary Anaerobic Pathogenic
Dietary Cholesterol Bacteria __ Clostridium
Cholesterol In Feces Animal Protein Putrefaction
Constipation Animal Carbohydrates Fermentation
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body _____________________________________________________________________________________________________________ p 19-2
TABLE FOUR: Thirteen of the Top Fifteen Killing (TFK) Diseases Identified as Dietary Cholesterol and Related Diseases and Syndromes (DCRDS):
Comprehensive Results of the DCRDS Systems Analysis Body Flow Chart
Common Disease/Syndrome Name Dietary Cholesterol & Animal Lipoprotein Auto-Immune Disease/Syndrome Disease/Syndrome Conventional Holistic Vegan Diet
Implicated (L-P) LCA Bile Acid Implicated (C-B) Etiology Etiological Pathology Physiology Treatment Treatment Preventable
(Medical Science Name) Etiology Primary (P) Secondary (S) ] Element S- Surgical (xxx %)
[Primary (P) Secondary (S) C- Chemotherapy
R- Radiation
#2. Cancers (continued)
d. Breast (Female) P S
e. Prostrate (Male) P S Constipation
Colonic Anaerobic
f. Non-Hodgkin Lymphoma P S Bacteria
g. Skin P Melanocyte
(Melanoma) Mutated Clones
h. Kidney P S
(Kidney/Renal/Pelvic Area)
i. Urinary Bladder P
j. 1.) Leukemia P S T Cell
2.) Myeloma P Plasma Cell Amyloid Deposits
3.) Lymphoma P B-Cell Amyloid Deposits
B-Cells
k. Ovary/Womb/Cervix P P Human Papiloma Virus
l. Thyroid (Female) S P
m. Pancreatic P P High Diabetes 99% Exocrine
Mellitus Incidence Pancreatic Related
#3.' Iatrogenic
[Doctor Caused] P S
[Health Care Professionals [Health Care Professionals
are Not Taught BA Metabolism are Not Taught Proper Human
or Proper Human Diet] Enteric (Intestinal) Hygiene]
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body _____________________________________________________________________________________________________________ p 19-3
TABLE FOUR: Thirteen of the Top Fifteen Killing (TFK) Diseases Identified as Dietary Cholesterol and Related Diseases and Syndromes (DCRDS):
Comprehensive Results of the DCRDS Systems Analysis Body Flow Chart
Common Disease/Syndrome Name Dietary Cholesterol & Animal Lipoprotein Auto-Immune Disease/Syndrome Disease/Syndrome Conventional Holistic Vegan Diet
Implicated (L-P) LCA Bile Acid Implicated (C-B) Etiology Etiological Pathology Physiology Treatment Treatment Preventable
(Medical Science Name) Etiology Primary (P) Secondary (S) Element (xxx %)
[Primary (P) Secondary (S}
#3. Stroke S P Blood/Brain Triglyceride Atherosclerotic 100%
Barrier Esterified Placques
Breached Dietary
Cholesterol Vitamin D
in Blood serum Deficiency
from Dietary
Metabolic Cholesterol
Syndrome Down regulation
#4 a. Asthma S P Thick mucus Breathing distress 100%
#4. b Emhysema S P Lung Tissue Breathing distress 100%
waste
#4 c. Bronchitis S P Cilia loss Thick mucus 100%
#5. Accidents Not Applicable Not applicable
#6. Diabetes Mellitus P P Yes_ Daily White Blood Cell Insulin Producing 100%
Vitamin D3 Mutated Clones
Deficiency
from
Dietary
Cholesterol
a. TI _ adolescent P P Beta cell death Islet Cells attacked TI _ thin
daily
b. T2 _ adult P P T2 _ obese
75% Metabolic
Syndrome: Fasting
Glucose Intolerance
#7. Alzheimer's Disease P S Yes White Blood Cell Amyloid & Tau Protein Fibrils 100%
Placques Mutated Clones Deposit Placque
Blood/Brain Diabetes Associated High Aluminum
Barrier breached
#8. a. Influenza S P Pathogenic virus High Body Temp. 100%
#8. b. Pneumonia S P Pathogenic bacteria 100%
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body _____________________________________________________________________________________________________________ p 19-4
TABLE FOUR: Thirteen of the Top Fifteen Killing (TFK) Diseases Identified as Dietary Cholesterol and Related Diseases and Syndromes (DCRDS):
Comprehensive Results of the DCRDS Systems Analysis Body Flow Chart
Common Disease/Syndrome Name Dietary Cholesterol & Animal Lipoprotein Auto-Immune Disease/Syndrome Disease/Syndrome Conventional Holistic Vegan Diet
Implicated (L-P) LCA Bile Acid Implicated (C-B) Etiology Etiological Pathology Physiology Treatment Treatment Preventable
(Medical Science Name) Etiology Primary (P) Secondary (S) Element (xxx %)
[Primary (P) Secondary (S}
#9. KIdney Diseases S P Triglyceride Stones block Urine Calcitonin absorbs calium 100%
Esterified Flow to Urinary Bladder
Dietary and made 80% from
Cholesterol Dietary Cholesterol
in Blood serum and 20% Calcium.
Free Dietary
Cholesterol ,
Ureas, Uric Acid
In Blood serum
#10. Scepticemia S S Triglyceride High Urea 100%
[Blood Poisoning] Esterified Anerobic Enteric Pathogens
Dietary High Uric Acid
Cholesterol
in Blood serum Acid pH Blood
Anerobic Low Serum O2
Serum Pathogens
#11. Suicide S P Yes Low Vitamin B Depression 100%
Complex
Low Melatonin
Low Melatonin
#12. Liver Cirrhosis & Other P S Triglyceride Stones block Bile 1 pint cold pressed 100%
Diseases and Gall Bladder Esterified Flow to Gall Bladder & Olive Oil on 2 nights
(GB) Stones Dietary Its constriction ability. consecutively
Cholesterol to expel Stones causes Gall Bladder to
in Blood serum and made 80% from expel stones into
Dietary Cholesterol and small intestines.
Free Dietary and 20% Calcium.
Cholesterol in
GB Bile High Lithocholic Acid
High Animal
Protein
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body _____________________________________________________________________________________________________________ p 19-5
TABLE FOUR: Thirteen of the Top Fifteen Killing (TFK) Diseases Identified as Dietary Cholesterol and Related Diseases and Syndromes (DCRDS):
Comprehensive Results of the DCRDS Systems Analysis Body Flow Chart
Common Disease/Syndrome Name Dietary Cholesterol & Animal Lipoprotein Auto-Immune Disease/Syndrome Disease/Syndrome Conventional Holistic Vegan Diet
Implicated (L-P) LCA Bile Acid Implicated (C-B) Etiology Etiological Pathology Physiology Treatment Treatment Preventable
(Medical Science Name) Etiology Primary (P) Secondary (S) Element (xxx %)
[Primary (P) Secondary (S}
#13. High Blood Pressure P P Vitamin D3 High Serum Sugar Foam Cells 100%
[Hypertension] Deficiency High Serum (Cholesterol
from Cholesterol Filled Mast
Dietary Cells)
Cholesterol
Atherosclerotic
Placques
#14. Parkinson's Disease P S Mid-Brain White Blood Cells Low Dopamine 100%
[Shaking Palsy] Substantia Nigra Mutated Clones Neurotransmitter
Neurons killed
#15. Atherosclerosis Vitamin D3
Deficiency
Dietary
Cholesterol
a.) cardiovascular P P Placques Triglyceride High LDH 100%
With Calcium Esterified Low HDH
Foam Cells Dietary High Homocystene
Cholesterol High BP
in Blood Serum High Serum CA
50% Metabolic
Syndrome
b.) peripheral vascular disease P P 100%
#16. Metabolic Syndrome P P C-reaction 50% Metabolic MS 9 Risk Factors: 100%
Protein Syndrome
Fibrinogen a.) increased waist
Interleukin 6 circumference
Tumor Necrosis (overweight & obesity)
Factor –Alpha b.) elevated blood triglycerides
c.) low blood HDL cholesterol
d.) high blood LDL cholesterol
e.) high blood uric acid
f.) high blood pressure
g.) fasting blood glucose
h.) increased blood coagulation
i.) in women high androgen levels
j.) in men high estrogen levels
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body _____________________________________________________________________________________________________________ p 19-6
TABLE FOUR: Thirteen of the Top Fifteen Killing (TFK) Diseases Identified as Dietary Cholesterol and Related Diseases and Syndromes (DCRDS):
Comprehensive Results of the DCRDS Systems Analysis Body Flow Chart
Common Disease/Syndrome Name Dietary Cholesterol & Animal Lipoprotein Auto-Immune Disease/Syndrome Disease/Syndrome Conventional Holistic Vegan Diet
Implicated (L-P) LCA Bile Acid Implicated (C-B) Etiology Etiological Pathology Physiology Treatment Treatment Preventable
(Medical Science Name) Etiology Primary (P) Secondary (S) Element (xxx %)
[Primary (P) Secondary (S}
#17. Obesity P P High Serum Fatty Acids _LDL 100%
Associaited with all cancers High Serum Cholesterol
but bladder, brain and skin
#18. Lupis S P red blood cells collogen 100%
dysfunction
#18. Assaults NOT APPLICABLE NOT APPLICABLE
#19. Multiple Sclerosis neuron myelon Steroids 100%
sheath cells
#20. Shizophrenia 32% Metabolic 70% women
Syndrome
#21. Depression
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 47

Now with the passage of Health Care Reform Legislation America can properly implement an
innovative infant and maternal mortality amelioration initiative that if it includes the 7 elements
specified below would within 24 months show a significant lowering of the genocidal level of maternal
and infant death that exists all over America especially in its inner cities amongst Afro-Americans.

a.) Recommend that participating doctors and other health practitioners implement a no Dietary
Cholesterol regimen with no more than 5 mg/day for women who are:

1.) preparing for pregnancy;

2.) pregnant;

3.) overweight or obese at risk for maternal and/or infant mortality; and

4.) residing in America's inner cities at risk for subclinical malnutrition, birth defects
and alcohol/drug syndromes.

b.) Monitor pregnant women with serum bile acids at or greater than 10 micro-grams/liter as
potential candidates for Intrahepatic Cholestasis in Pregnancy (ICP) noting that 40 micro-
mol/liter is a biomarker for ICP fetal complications.

c.) Identify Metabolic Syndrome as a maternal and infant death risk factor targeting especially
over weight and obese pregnant women.

d.) Adding the monthly 2 quart “high enema” as a pregnancy preparation and pregnancy
gestation regimen especially targeting those with ICP.

e.) Follow a Dietary Cholesterol detox dietary regimen daily especially including:

1.) fresh Mexican Papaya, berry (straw, black, rasp, blue) and freshly squeezed orange juice.

2.) fresh squeezed carrot juice with spinach, celery, beet and elephant garlic.

3.) spinach and Romaine salads with “cold pressed” olive oil, avocado and garlic.

4.) raw sunflower seed and pumpkin seed drink or milk.

5.) Cell Tech, Inc. Klamath Lake, Oregon “Super Blue Green Algae.”

6.) Solgar, Inc. a.) Horse Tail; b.) “Oceanic” and c.) probiotic acidoplis and bifida

7.) fresh squeezed Concord grape juice.

f.) Encourage the US Federal Executive Branch to empower the Environmental Protection
Agency to create green job grants to non-profits and governmental units targeting cleaning
the urban areas of litter __ especially zeroing in on plastics, as their UV light deterioration
pollutes the water table and drinking water with low levels of hydrocarbon mutagens, carcinogens
and cytotoxins showing up in Mother’s milk and allows for the bile acids and other TABLE III
identified co-mutant, co-carcinogen and co-toxin derivatives to promote.

g.) admit the truth of science that the human is a genotype vegan/herbivore and proceed to feed
Mother and baby accordingly in all federal fund receiving hospitals and health care centers.

h.) recognize that the human infant is infected in the maternal womb by pathogenic anaerobic
bacteria and that prevention is the effective and cost efficient strategy easily accomplished
via nutritional herbology regimes as maternal pregnancy preparation and during pregnancy
without any danger to mother or infant occurring using 1.) the vegan diet; 2.) the Dietary
Cholesterol detox dietary regimen daily; and 3.) the intestinal anaerobic pathogenic bacterial
cleansing regimen targeting a.) gastric colonizing Helicobacter pylori; b.) small intestines and
liver enterohepatic colonizing Helicobacter hepatica bacteria; and c.) the anaerobic toxemia
bacteria colonizing the large intestines.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 48

IX. The American Cancer Society, American National Cancer Institute’s AARP
and European Longitudinal Studies of “Meat Intake and Mortality

In summary the 70 year suppression of "the great pathophysiological ramifications of dietary


cholesterol and bile acid metabolism” knowledge in question that the Makishima’s May, 2002
Science Magazine article made visible is:

a.) that the human liver metabolizes Dietary Cholesterol into the detoxified excretory product the "so-
called" Primary Bile Acid of Chenodeoxycholic acid (CDA) and its glycine and taurine Bile Salts;

b.) that in turn pathological anaerobic bacteria in toxemic colon conditions degrade the CDA and its Bile
Salts into the so-called Secondary Bile Acid Lithocholic Acid (LCA) and transient other Tertiary Bile
Acids metabolites; and

c.) that Dietary Cholesterol, CDA and LCA are the mutagenic and carcinogenic causes of
colorectal cancer in those susceptible humans.

Three landmark epidemiological/observational longitudinal (multiyear) studies of the connection


of the Omnivore diet and cancer have been published since Makishima’s May, 2002 Science
Magazine article found a significant statistical association of the eating of animal meat with the
occurrence of colorectal cancer as follows:

1.) the January, 2005 JAMA published American Cancer Institute study [D 7];

2.) the July, 2005 Journal of the British National Cancer Institute published
European Prospective Investigation [D 8]; and

3.) the March, 2009 Archives of Internal Medicine published American


National Cancer Institute (NCI) study [12]. All 3 studies involving totally
nearly 2,000,000 participants.

The latest and largest of these three landmark epidemiological/observational longitudinal studies
sponsored by the American NCI illustrates best the continued suppression of bile acid metabolism
knowledge in question. The American NCI study recruited over 500,000 participants from the
American Association of Retired Persons (AARP) AARP the senior citizen lobbying non-profit
organization being healthier than most senior citizen groups in America.

The March 24, 2009 AP review article of the National Cancer Institute (NCI)’s AARP entitled "Study
tallies risks of eating meat" by the Associated Press (AP) journalist Carla K. Johnson from the
Indianapolis Star newspaper reviews the above cited NCI longitudinal study journal citation is Sinha,
Rashmi, et al, “Meat Intake and Mortality”, Archives of Internal Medicine, V. 169, No. 6, March 23, 2009.

Please note that the newspaper article nor the journal article reflect the etiological knowledge of
"the great pathophysiological ramifications of dietary cholesterol and bile acid metabolism" by
the researchers officially or the journalist released the first 3 months of the Obama administration at
the beginning of the National Health Care Reform Legislation public debate.

Further illustrative that the Health Care Reform Legislation public debate was and continues to be
oblivious to "the great pathophysiological ramifications of dietary cholesterol and bile acid
metabolism" is the September 7, 2009 Los Angeles Times article by Journalist Janet Hooks entitled
"Health-care reform: Could a smaller dose work?" The article includes quotes by the AARP leadership
and was carried by the Indianapolis Star newspaper. The AARP Legislative Director John Rother's
response to whether the proposed Health Care Reform Bill should be legislatively enacted as a whole
or in increments being too far reaching and costly in a recession follows:

"You can't just do half the bill .... It is an interconnected set of policies."

Nowhere does he cite the sickness prevention implications of the March, 2009 released 10 Year
Longitudinal Study of “Meat Intake and Mortality” which used ARRP Members as its participants
pointing to the great savings in health care expenditures that could be derived from a properly
implemented Health Care Reform with vegan and vegetarian dietary lifestyle change incentives. It is
clear that the AARP leadership nor any other consumer lobbyist is aware of why the study in question
found a "modest risk increase" in contracting cancer by ingesting the most dangerous of Dietary
Cholesterol sources mammalian red meat. This National Security issue omission is a result of the
70 years of suppression of "the great pathophysiological ramifications of dietary cholesterol and
bile acid metabolism."
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein
in the Aboriginal Vegan Genotype Human Body” ______________________________ p 49

X. Misconceptions of the Allopathic Medical Sciences

Consequently, as a result of over 70 years of suppressing "the great pathophysiological


ramifications of cholesterol and bile acid metabolism" the allopathic and osteopathic medical
sciences of biochemistry, physiology, pathology, dietetics and microbiology and secondarily the others
have been found corrupted before and since the suppression of the 1946 through 1966 journal article
publications of the finding by Izrael Hieger, D. Sc. that Animal/Dietary Cholesterol is a mutagen and
carcinogen. This suppression continued with the 1974 published ground breaking article by T. Narisawa
connecting the cause of colorectal cancer with the Animal/Dietary Cholesterol liver detox product the
primary bile acid Chenodeoxychoic acid and its colonic pathogenic anaerobic bacterial degradation the
secondary bile acid Lithocholic acid as a carcinogen must end. Try acquiring this article to
experience suppression of science in effect now.

Although it will take decades for these misconceptions to be properly resolved it is time to expose the
most important ones noting that many are in the process of being properly resolved now.

A.) Human Nutrition Misconceptions

1.) The aboriginal diet of human beings (homo sapiens) is the Omnivores Diet; instead of the truth that
the aboriginal human diet was the Vegan Diet and that this aboriginal Omnivores Diet misconception
derives from the socio-political economic bias of those using and profiting from the Omnivores Diet
upon which Western Culture is based.

NOTE: Multidisciplinary analyses presented herein as Appendixes A-1 and A-3 clearly documents that the
aboriginal human diet was and by definition still is the Vegan Diet. This is by no coincidence identified
in the Bible Genesis 1: 29 as the “vegan directive for human nutrition.” Appendix A-2 clearly shows that
the Essene Hebrews who raised John the Baptist and his cousin Jesus Christ, his key Apostles and
the aboriginal Christians (Gnostic) were all vegans.

2.) The molecular components of animal flesh and organs are naturally assimilated into the human
body; instead of the truth that the human liver which over sees food digestion and body poison
detoxification reacts to Dietary Cholesterol and its related animal protein and fat residues as foreign
bodies and initiates the antigen immune system and inflammatory response whose white blood
phagocytes ingest the Dietary Cholesterol and white blood lymphocytes make antibodies against
analogous to the body’s rejection of organ transplants which must be countered with strong adrenocortex
hormone mimicking drugs least they rot and kill the recipient.

B.) Human Biochemistry Misconceptions

1.) The homo sapiens sapiens genome is genetically set up for accommodating the Omnivore Diet;
instead of the truth that the human genome of modern humans as reflected in the “Biblical Human
Nutritional Directive” of the Bible Genesis 1: 29 is set up for a Vegan/Herbivore Diet supported most
uniquely by the matrilineal inherited Mitochondria cellular organelle that has its own DNA where a.)
in the adult lung reacts to Oxycholesterol 27 a oxidative decomposed stage of Dietary Cholesterol in a
series of acid bile acid metabolic reactions that detoxifies it so when it reaches the liver it is further
detoxified to Chenodeoxycholic Acid (CDCA); and b.) during human gestation of an infant the
human fetus reacts to Oxycholesterol 27 the oxidative decomposed stage of Dietary Cholesterol in
an even broader series of acid bile acid metabolic reactions that protect it from a toxic death.

1.) Although the human lungs absorb (fix) Oxygen (O2) through the use of the enzyme Oxygenase present
in red blood cells it does not similarly use the ample enzyme Nitrogenase present in red blood cells to
fix Nitrogen (N2) and make amino acids thus there is a high dietary protein need; instead of the
truth that a healthy human on a proper Vegan Diet fixes both O2 and N2 into the blood stream during
each breathe to be used by the body cells for O2 and N2 based energy production and synthesis of
human body elements of amino acids/proteins, carbohydrates/polysaccharides, fats/steroids, vitamins,
enzymes and coenzymes and hormones.

2.) Vitamin B12 can only be obtained from an Omnivorous Diet specifically from animal meat, instead of
the truth that Vitamin B12 and the entire Vitamin B Complex are made by natural probiotic bacteria
Acidophilus and Bifidus in the small and large intestines. The charge such beneficial bacterial’s B-12 is
not absorbed because they are not in the small intestine is a reflection of the pathological Toxemic
conditions of the colon which is easily redressed via “high enemas” and probiotic recolonization. Oral
B-12 capsules and reinforced foods are readily available.

3.) Vitamin B12 needs an absorption element Intrinsic Factor made in the stomach of the Omnivorous
human which allows the vitamin to be absorbed into the blood stream from the Gastro-Intestinal (GI)
tract, instead of the truth that Intrinsic Factor is made simultaneously along with Vitamin B12 by
natural probiotic bacteria Acidophilus and Bifidus in the small and large intestines.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 50

4.) the 20 human amino acids are composed of the 11 non-essential amino acids (which can be
synthesized by the liver) and the 9 essential amino acids (which must be obtained from dietary
sources) and requires a high protein animal based Omnivorous Diet; instead of the truth that a
healthy person capable of Nitrogen fixation in the lungs can best obtain all 20 human amino acids
through a.) synthesis by the small and large intestinal mucosa cells; b.) synthesis by the liver’s hepatic
cells, and c.) sourced from the aboriginal low protein plant based Vegan Diet.

5.) Originally, in the 1950’s the Secondary Bile Acids were so named as it was thought they were made by
the liver and as result of normal physiology, instead of the truth that they were found in the 1980’s to be
the result of a chronic interconnected “vicious circle” toxemia of the colon and blood stream involving
a.) undigested animal pseudo” food residues; b.) an acid pH blood stream and colon from a gas and acid
producing polysaccharide anaerobic bacterial fermentation and c.) generation of carcinogenic toxins
from a fat and protein anaerobic bacterial putrefaction from the Omnivorous Diet including the
production from the “so-called” Primary Bile Acid CDCA of the Secondary Bile Acid named
Lithocholic Acid (LCA) which induces colorectal cancer.

C.) Physiological Misconceptions

1.) The Primary Bile Acid named Cholic Acid (CA) is primarily produced as an emulsifier of the digestion
of dietary fat in the small intestinal food chyme; instead of the truth that Cholic Acid (CA) is largely a
detoxification and excretement product from Endogenous Cholesterol derived from damaged and worn
out human cells of all types by the Liver’s hepatic cells using 7-Alpha Dehydoxylase enzyme that are
dumped in the Gall Bladder for fecal expulsion from the body and that the pharyngeal lipase, gastric
steapsin and pancreatic lipase digestive enzymes digests the food chime fat with or without primary bile
acid CA emulsification.

2.) The “so-called” Primary Bile Acid named Chenodeoxycholic Acid (CDCA) is primarily produced as an
emulsifier of the digestion of dietary fat in the small intestinal food chyme; instead of the truth that
Chenodeoxycholic Acid (CDCA) occurs only in Omnivores and Vegetarians as a detox product of
Dietary (Exogenous or Animal) Cholesterol by:

a.) the Liver’s hepatic cells using 7-Alpha Dehydoxylase enzyme derived from the enterohepatic
circulation that is dumped in the Gall Bladder for fecal expulsion from the body; and

b.) by blood stream vascular endothelial cells and other body epithelium and endothelial
cells using a mitochondrial enzyme 27-Sterol Dehydroxylase.

3.) The secondary bile acids named Deoxycholic acid (DCA) and Lithocholic acid (LCA) are fat emulsifies
instead of the truth they are colonic pathogenic anaerobic bacteria toxins and co-carcinogenic agents
promoting mutagenic neoplasms further degraded into transient tertiary bile acids many also mutagenic
and carcinogenic.

.4.) That the female human menstruation is normal with its Premenstrual Syndrome complications and
hysterectomy surgical interventions of excessive vaginal bleeding; instead of the truth that
menstruation is a preventable syndrome caused by the acid pH blood condition that is generated by
the Omnivorous Diet because conception of a fertilized egg via sperm can not happen with an acid pH
blood stream, vagina and womb placenta.

NOTE: Esoterically menstruation is hemorrhage purging of acid blood and womb placenta through the
vagina occurring monthly to prepare for conception next month from meat eating.

5.) That a natural lack of female menstruation (amenses) from basic pH blood is an abnormal condition
of women on a Vegan Diet or anorexic or a hormonal pituitary gland problem of amenorrhea; instead
of the truth that the amenses condition is a natural result of the Vegan Diet reflecting the inner sanitation
revered by ancient Native American and Eastern Cultures including the Essene Hebrew Priestess Mary
who bore Jesus Christ in an “immaculate” amenses body “conception.”

6.) That the female human menopause is a natural condition of female human aging; instead of the truth
that menopause is a preventable syndrome from years of menstruation based malnutrition and from the
improper ingestion of Dietary Cholesterol containing “pseudo foods” of animal and dairy.

7.) That the normal healthy human average life span is 80 years of age instead of 130 years of age as
computer simulations including the Oracle AZ. Biosphere Project and declared in the Bible Genesis.

8.) That the heart is the pump of the blood circulatory system instead of the heart is the valve and the
atmospheric connected lungs being the real pump of the blood stream and thus air pollution by
industrial, petroleum internal combustion engine powered vehicles and litter can no longer be tolerated.

9.) That although the mouth cavity and teeth are analogously washed daily that the ancient wisdom of 3
days a month use of “high enemas” is unnecessary instead of the truth a monthly water irrigation
targeting cleansing the colon and rectum of Omnivore food wastes generically called “mucus” is the
basis of an effective sickness prevention regime dating back to Ancient Egypt/Kemit.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 51

D.) Pathology Misconceptions

1.) The intestinal bacterial flora should be dominated by E. coli, Bacteriodes and other anaerobic pathogenic
bacteria which are continually recolonized from the daily ingestion of more “slow poison animal flesh
“pseudo” foods instead of the truth that pro-biotic technology of introducing and maintaining Vitamin
B-12 and the other Vitamin B complex synthesizing Acidophilis and Bifidus beneficial bacteria sustained
by plant derived steroids.

2.) That ”Heart burn” is caused by an over production of gastric (HCL) acid instead of the meat eating
generated pathology of too much blood (serum) urea which leaks into the stomach allowing colonization
by heliocobactor pylori bacteria associated with hiatus hernias, gastric and duodenal ulcer and cancer.

3.) That pathogenic bacteria and viruses are the cause of infectious diseases instead of the insanitation
from eating animal flesh resulting in putrefaction of proteins and fats and fermentation of connective
tissue polysaccharides resulting in acid blood and gas formation.

4.) That the normal food passage time through a healthy human is 65 hours instead of 24 hours meaning
most of their patients are chronically constipated and hosts to colonic pathogenic, mutagenic and
carcinogenic toxemia.

XI. The Solution of Prevention of Sickness Education and Practice Incentives

A. The Aboriginal Human Diet

During the last 50 years since the publication of the 1959 article by Hieger, Izrael, D. Sci.,
“Carcinogenesis of Cholesterol” (British Journal of Cancer, V. 8 (3), pp 439-51) the allopathic
medical sciences of dietetics, biochemistry, physiology, pathology, microbiology, and secondarily the
others have further ignored definitive evidence of the connection of animal meat derived cholesterol and
bile acids and colon cancer by suppressing "the great pathophysiological ramifications of dietary
cholesterol and bile acid metabolism."

It is easy to understand that Human Nutritional Science is still holding onto the misconception that the
aboriginal diet of human beings (homo sapiens) is the Omnivores Diet; instead of embracing the
truth that the aboriginal human diet was and still is the Vegan Diet. This misconception derives from the
socio-political economic bias of those scientists who were born into Omnivores Diet using families and
are encouraged to continue this misconception from the special interests which are profiting from the
Omnivores Diet upon which Western Culture is based.

However, Appendix A-1 based on an exhaustive multidisciplinary analyses of documents listed in


Bibliography B. indicates that the aboriginal human diet was and by definition still is the Vegan Diet.
Thus it is no coincidence that the Vegan Diet is identified in the Bible Genesis 1: 29 as the “directive
for human nutrition.” Quoting from Hilton Hotema’s The Great Law (1962) page 13 [emphasis added]:

“There was never a time in the history of humanity when the question of diet, in its relation to
health and disease, has received the earnest attention that it is receiving now. But each worker
has his own pet theory, and his prejudice will not permit him to consider anything that fails to
support his theory ...”

“The Law of Diet is simple and sure as the Law of Gravitation. It was understood by early man,
just as it is understood today by the beasts of the field and the fowls of the air. But flood and famine
diverted man from the true course, and it appears that knowledge of diet was lost.… [Bible
Genesis 1:29] foods that come from the soil …. Its discovery means the dawn of a new era in
human life. It will furnish a foundation which future generations will create a new civilization.”

Is America going to rise to the international metaphysical occasion and lead the world into the Golden
Age of peace, artistic and craft creativity and prosperity, sans hunger and poverty, pollution and war
and civil war? No if it continues to deny the scientific evidence that the Omnivore Diet is novel and
experimental and has been found from multidisciplinary to be:

1.) a “slow poison” to the human body causing blood poisoning, cancer, chronic infection and toxemia of the
intestinal tract and organ necrosis (including brain, heart, liver, pancreas and kidneys);

2.) fosters a non-sustainable animal husbandry based agriculture polluting air, water and soil; and

3.) is ineffective and inefficient in person hours and resources in feeding the people.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 52

B. USDA Food Group Pyramid Needs to


Reflect “Bile Acid Metabolism
Ramifications”

2010 United States Department of Agriculture (USDA) Food Group Pyramid & Food Guidelines

The 2005 USDA Food Group Pyramid has been getting progressively better from the “Food Group
Square” of the 1980’s for example incorporating many of the Asian and Mediterranean Diet elements.
But the just released in January 2010 and shown below USDA Food Group Pyramid and Food
Guidelines continues to omit "the great pathophysiological ramifications of dietary cholesterol and
bile acid metabolism." The following improvements are suggested incorporating "the great
pathophysiological ramifications of bile acid metabolism" and the basis of aboriginal “nutritional
herbology:”

a.) The GRAINS GROUP (Bread, Cereal, Rice and Pasta) is excellent.

Note: All grain products should be recommended 100% whole grain breads, cereals
and pastas and brown, wild or Indian Basmati rice.

b.) The VEGETABLE GROUP is excellent.

Note: The 100% vegetable juices should be added and emphasized to help adults and
the youth to get their minimum RDA’s which they are not now getting.

c.) The FRUIT GROUP is excellent.

Note: The 100% fruit juices should be added and emphasized to help adults and the
youth to get their minimum RDA’s which they are not now getting.

d.) The MILK GROUP needs these improvements:

#1. require this Group does not contain any Dietary Cholesterol by requiring cow milking
machines and other techniques that do not suck milk sack cells and by not using rennet
as a cheese coagulant using instead other natural plant derived coagulants like citric acid.

#2. require this Group add the vegetable, seed, beans, grain made milks and cheeses; e.g.
made from rice, soy beans, sunflower, almonds and other seeds, nuts and grains.

e.) The MEAT AND BEAN GROUP __ including Mammalian, Poultry, Fish, Dry Beans, Eggs,
Nuts and Seeds ____ needs the following change improvements:

#1. Change Title to NUT MEAT, SEED, BEAN AND LEGUME GROUP.

#2. to avoid Dietary Cholesterol it is suggested changing the elements Animal Meat,
Poultry, Fish and Eggs to a sparing and abstinence option.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 53

#3. explain the utility of adding and/or increasing the most superior protein sources of nature the
tree nut meats ; e.g. pecan, pinion, almond, walnut, hazel nut, coconut and the seed food
elements; e.g. sunflower seeds, pumpkin seeds, sesame seeds, caraway seeds to the
remaining Dried Beans and Nuts Group.

Note: Clearly fresh unroasted and unsalted fresh nut and seed meats are
superior to roasted and salted “processed” ones.

#4. “Peanuts” should be clearly clarified as being misnomer as they are beans.

#5. Cooked Beans and legumes should be emphasized as second best to fresh
nuts and seeds.

f.) Advise the use of the Monounsaturated and Polyunsaturated Vegetable Fats and Oils __
noting their health benefits in preventing cardiovascular and other atherosclerotic diseases.

#1. cold pressed olive oil, avocado oil, flax seed and sunflower oils should be used daily.

#2. fried vegetable oil foods should be used sparingly.

#3. fried animal oils should be avoided.

#4. The special case of coconut oil must be refrigerated at all times.

#5, The special case of bean oils like peanut and soybean oils must be stressed

$6. The danger of heating oils especially frying and Chinese style Wok cooking with them
must be emphasized should be sparingly used and best avoided.

g.) The ancient wisdom of using spices many which are antioxidant as Turmeric, Cinnamon,
Basil, Black Pepper, sea salt.

h.) danger of common table salt sprayed with aluminum bauxite refining by product instead
using iodine sea and rock salt.

i.) wisdom of using dehydrated sugar cane, honey and grade A maple syrup and avoiding
fructose and chemical processed sugar cane and beet sugar.

j.) wisdom of using apple cider vinegar and avoid other vinegars and alcohol extracted
condiments and spices.

The synthesis of in vitro, in vivo and observational/epidemiological scientific research evidence


iconoclastically shows that the Omnivore Diet produces the chronic diseases and syndromes that are
debilitating and killing Americans and consuming America’s health care expenditures.

C. Some Examples of Appropriate Diets that Limit, Avoid and Cleanse


Dietary Cholesterol and Related Residues

The allopathic medical establishment’s biased criticism of the aboriginal Vegan Diet and the later
accommodating Vegetarian Diet as deficient for example in complete amino acids, Vitamin B-12 and
its Intrinsic Factor, iron and zinc are unscientific allopathic medicine mythologies. This is shown
by these diets’ use of the complete amino acid containing soy bean, peanut and sunflower seed and
combination legume and whole grains food products; their use of probiotic beneficial bacteria
Acidophilus and Bifida (which naturally make vitamin B-12 and its intrinsic factor in the human
intestinal tract) and the use of the fresh green vegetables like spinach, fresh fruit like grapes and dried
fruits like raisins (dried seedless grapes) have abundant iron, and whole wheat bread and better yet
fresh pumpkin seeds and the “stone fruits” like fresh plums and dried fruit like prunes (dried plums)
have abundant zinc.

Clearly, a modified Mediterranean Diet based on Italian, Greek, Southern France and/or North African
cuisines which avoids animal meat and has already been proven palatable to Americans with whole
seeded grape juice substituted for wine, adding non-dairy cheeses and milks made from soy bean
and rice for variety and expanded with the modern food science “mock meats” made of soy bean,
wheat gluten or other beans/legumes and of course the avocado and olive and olive oil would be one of
the suggested dietary life style changes of the proposed Health Care Reform Legislation's proper
sickness prevention education and practice implementation.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 54

The Asian Diet relying on the Macrobiotic brown rice foundation and Mexican and other popular
international cuisines can be easily modified with non-dairy cheeses and milks, “mock meats” and of
course the nuts, seeds, legumes and whole grains in combination to replace the chronic disease
and syndrome generating animal meat and dairy product Dietary Cholesterol and saturated fats.

The Cardiovascular Disease Reversal Diet designed by Dr. Dean Ornish, MD., CEO of the
Preventive Medical Research Institute, Inc. [Programme for Reversing Heart Disease, Ivy Books,
U.S. (Jan 1996)] and his other less rigorous Prevention Diets should be one of the suggested dietary
life style changes of the Health Care Reform Legislation's proper implementation of sickness
prevention education and practice.

Finally, the “Daniel 365 Diet” of my design based on Bible Genesis 1: 29 and Book of Daniel will
reverse the ”Nutritional” or Dietary Cholesterol and Related Diseases and Syndromes (DCRDS),
and removes years of Dietary Cholesterol and its related Animal Protein and Animal Fat residues.
Appendix F is based on this paradigm available for free in the Original Prevention of Sickness
Pamphlet downloadable at http://www.theuniversityofgod.org/Page8.html.

D. Global Warming, Environmental and Food Production Benefits

Appendix A-1 and Appendix A-3 reveal that circa 3,000,000 BCE the European Caucasian and Asian
sub-races set into motion the Quaternary Ice Age with its catastrophic changes to earth’s
astrophysics (upside down & off axis), climate and ecology dominated by sand and ice deserts by:

a.) the invention of hunting wild animals;

b.) the disastrous experimenting with the Carnivore Diet;

c.) the adoption of the novel Omnivore Diet; and

d.) the unnecessary invention of domesticated animal husbandry based agriculture as opposed to
the continued use of the Bible Genesis documented aboriginal Vegan Diet and complementary
aboriginal sustainable horticultural forestry (agri-forestry) gardening the legendary Garden of Eden.

Appendix E presents the courageous and “state of the art” editorial by Doctor Dean Ornish, MD in
the May, 2009 American Journal of Cardiology entitled “Mostly Plants” where he argues elegantly
the following:

a.) the Vegan and Vegetarian Diets should be recognized by the allopathic medical community as
the inevitable sickness prevention life style change that is superior to the Omnivores Diet;

b.) the Vegan and Vegetarian diets would eliminate the $20 Billion a year use of the “statin”
Dietary Cholesterol reduction drug for a health reform savings of $200 Billion over 10 years; and

c.) the Vegan and Vegetarian diets have the secondary benefits of significant environmental
pollution and poverty abatement where properly used.

Specifically, Dr. Dean Ornish, MD. states in “Mostly Plants”:

“Also, what’s good for you is also good for our planet. Animal agribusiness generates more
greenhouse gases than all transportation combined [Food and Agriculture Organization of the
United Nations. Livestock’s Long Shadow: Environmental Issues and Options. Available at:
http://www.fao.org/docrep/010/a0701e/a0701e00.HTM. Accessed June 9, 2009].”

“The livestock sector generates more greenhouse gas emissions as measured in carbon dioxide
equivalent than transportation (18% vs. 13,5%). Also it accounts for 9% of the carbon dioxide
derived from human-related activities. It generates 65% of the human-related nitrous oxide,
which has 296 times the global warming potential of carbon dioxide. Nitrous oxide and methane
mostly come from manure, and 56 billion “food animals” produce a lot of manure each day.”

“Also, livestock now use 30% of the earth’s entire land surface, mostly for permanent pasture but
also including 33% of global arable land to produce food for them. As forests are cleared to create
new pastures, it is a major driver of deforestation; some 70% of forests in the Amazon have been
turned over to grazing.”
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 55

“Finally, eating lower on the food chain is a more efficient way to produce protein. It takes
significantly more resources to produce meat-based protein than plant based protein. As the
earth’s population continues to increase and resources decrease, choosing to eat plant-
based foods frees up more resources to help feed others. Knowing that the food choices we
make each day not only help ourselves and our familys but also our planet often brings a
sense of meaning for many people, this is a powerful motivator.” (emphasis added)

The above Table 3 from F.R. Ellis, et al, “The Nutritional Status of vegans and vegetarians”
Symposium Proceedings of the Nutritional Society, V. 26, pp 205-11, 1967 adopted from the work
of Christenson, 1943 clearly shows that producing adequate food for a vegan population is more
efficient and effective than for a omnivore population. Yes, meat eating is inherently wasteful
being counter to the Great Law expressed in the Bible Genesis 1: 29 and thus is unnatural and
holds the key to ending the perpetual hunger and starvation that grips ½ of humanity!!!

XII. Projection of American Health Care Expenditure and Leading Causes of Death Reductions
in the World’s Costliest Health Care

A. Predicted Growth of Sub-Group D: Avoidance of Dietary Cholesterol Life Style Change

It is firmly believed that the US government and the American people themselves have the ability and
more importantly the "grit and integrity" to conceptualize the "big picture" now if they were properly
presented the “the great pathophysiological ramifications of cholesterol and bile acid
metabolism" as an unaddressed “Health National Security Issue.” America is predominately
Christian in religious faith and many Americans already practice during Easter Lent observation
abstinence from Dietary Cholesterol foods.

Multicultural based diets properly designed within the implemented sickness prevention education
and practices incentives program using menus based for example on the modified Mediterranean
Diet and the brown rice based Asian Diet would be ideal. Dr. Dean Ornan, MD’s brilliant coronary
vascular disease Reversal Diet and Prevention Diets as a model for those with DCRDS would be
very effective. Subsequently, the projected Sub-Group D would appear and the projected savings
crudely estimated below would accrue during 2012.

Specifically, it is projected that the American population's response to the proposed Health Care
Reform Legislation's proper implementation of sickness prevention education and practice
incentives including the suppressed "dietary cholesterol and bile acid metabolism ramifications"
and how to individually reverse their effects via body detox regimens for example the above cited Dr.
Dean Ornan, MD’s brilliant coronary vascular disease Reversal Diet or the “Daniel 365 Diet” will
produce 4 Sub-Groups by 2012 as follows:
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 56

Sub-Group A. 1/4 will ignore the knowledge as a "cultural" and economic attack on American traditions

Sub-Group B. 1/4 will experiment moderately with less animal based "cultural food" ingestion

Sub-Group C. 1/4 will experiment with being vegetarian and significantly lower red meat ingestion

Sub-Group D. 1/4 will embrace the vegan lifestyle and personal detox of body regimen

Consequently, with this knowledge of the "great pathophysiological ramifications of bile acid
metabolism" properly placed within the requisite prevention of sickness health education and
practices incentives activities of the proposed Health Care System Reform Legislation's
implementation; it is projected that Sub-Group D of 1/4 (25%) of the American people will decide to
avoid the ingestion of Dietary Cholesterol and allow their own livers to provide this vital body element
as Endogenous Cholesterol: By 2012 the Nation's Health Care Industry Expenditures would be
reduced by approximately 1/4 (25%) with the requisite body detoxing of Dietary Cholesterol and
its associated animal protein and animal fat residues saving $600 billion annually in America’s
health care costs!

B. Projected Reduction in Health Care Expenditures and Leading Causes of Death

Please study below the TABLE VI: American Projections: DCRDS Prevention Education
and Leading Causes of Death Averted and Money Saved Annually which presents the benefits
to Americans from implementing the National Health Care Reform Legislation with a properly designed
sickness prevention education program including avoiding the "great pathophysiological
ramifications of dietary cholesterol and bile acid metabolism."

Specifically, TABLE VI projects that under the just passed Health Care Reform Legislation if
the American population were appropriately educated about the ramifications of "bile acid
metabolism"; they would form the theorized target Sub-Group D and by 2012 there would be:

1.) annually a prevention of 466,895 American lives loss to the TFK's;

2.) annually health care cost savings of $3,128,196,500 in treating TFK incidences;

3.) by the end of 2022 over 10 years 4,668,950 American lives and $31,281,965,000
in American health care expenses would be saved from TFK deaths; and

4.) an annual $600 Billion total health care expenditure savings from sickness prevention
education and practices incentives.

C. Vegan and Vegetarian Diet and Body Detoxification Practice Incentives

It is can be clearly shown that the Top Fifeteen Killers (TFK’s) of Americans have a significantly lower
incidence amongst those following a Vegan diet and a “strict” Vegetarian Diet the latter avoiding rennet
dairy products and eggs with no more daily than 5 mg of Dietary Cholesterol. Ideally, those people
making the vegan & vegetarian lifestyle change should receive significantly discounted health
Insurance Premiums in any Health Care Reform Legislation that includes the cholesterol and bile
acid metabolism issues herein.

Consequently, it is projected that if 1/4 (25%) of the American people identified as Sub-Group
D were to decide to avoid the ingestion of Dietary Cholesterol and allow their own livers to
provide this vital body element; by 2012 the Nation's Health Care Industry Expenditures would be
reduced by approximately 1/4 (25%) with the requisite body detoxing of dietary cholesterol and its
associated animal protein and animal fat residues.estimated as follows:

$2.5 Trillion Dollars ($2,500,000,000,000) annual health care industry expenditure reduced 1/4
(25%) within Sub-Group D 1/4 (25%) or by $600 Billion Dollars a year starting in 2012!

In summary the Health Care Reform Legislation implemented with proper sickness prevention
education and practice incentives would beginning in 2012 annually result in a minimal $600 Billion
total health care expenditure savings. The Health Care Reform Legislation with an annual price tag
of approximately $100 Billion would continue to annually generate minimally a savings of $600 Billion IF
this knowledge of "the great pathophysiological ramifications of dietary cholesterol and bile acid
metabolism” is placed within the requisite Legislation's prevention of sickness education and
practice incentives implementation.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 57

TABLE VI

America Projections: DCRDS Prevention Education and Leading Causes of


Death Averted and Money Saved Annually

Disease Rate US Death Projected Projected Sub-Group D


(Common Name) Rate 2006 Sub-Group D Per Capita Health Costs
# of 2006 Deaths American Saved in America by 2012
Lives Saved ('06 per capita rate
by 2012 $6,700 used)

1.) Heart Disease 167,613 $1,123,007,100


671,250

2.) Cancers 139,950 $937,665,000


559,801

3.) Stokes 34,244 $229,434,800


136,976

4.) Asthma/ 31,137 $208,617,900


Emphysema/
Bronchitis
124,549

5.) Accidents Not Applicable na na


120,395

6.) Diabetes 18,106


$121,310,200
72,422

7.) Alzheimer's 18,103 $121,290,100


72,412

8.) Influenza/ 14,015 $93,900,500


Pneumonia
56,060

9.) Kidney 11,296 $75,683,200


Disease
45,182

10.) Scepticemia 8,366 $56,052,200


33,465

11.) Suicide 8,323 $55,764,100


33,292

12.) Chronic 6,887 $46,142,900


Liver Disease/
Cirrhosis
27,546

13.) Hypertension 5,964 $39,958,800


23,855

14.) Parkinson's 4,891 $32,769,700


19,565

15.Homicide Not Applicable


____________
_______________
TOTALS: 466,895 $3,128,196,500
LIves Saved Money Saved
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 58

XIII. Ideal Need to Convene a 2010 US Senate Select Committee on Human Nutrition and Human
Needs and/or US House of Representatives/Ways and Means Committee Hearing

It had been previously requested in the 2009-2010 health policy analysis and synthesis series called
the White/Blue/Red and Green Papers that the US Congressional Senate and House unpredictably
back the President’s lead in the health care reform effort by convening the necessary Hearings to
investigate and verify this dietary cholesterol and bile acid metabolism omitted issue suppressed by
the Special Interests targeting bipartisan implementation. The federal executive branch agencies
with the responsibility in this “Health National Security Issue Omission” are the US/Department of
Agriculture (USDA) establishing dietary standard guidelines and the US/Department of Health and
Human Services including its Food and Drug Administration (FDA) regulating food labeling and
vitamin and mineral RDA’s.

Consequently, the Purple Seal proposes that since the previously requested convening of a Select
Committee on Human Nutrition and Human Needs and/or US House of Representative/Ways and
Means Committee Hearing is politically impossible now that the National Republican Party has
made the US Congress passing of the Health Care Reform Bill a November, 2010 national election
issue and repeal target; that the White House Office of Health Care Reform hold a Forum on
American Maternal and Infant Mortality Etiology and Possible Solutions moderated ideally by Dean
Ornish, MD., Director, Prevention Health Research Center to address the complicated and
controversial etiological roles of Dietary Cholesterol and Bile Acid Metabolism.

The USDA and FDA are in need of help from the US Congress in properly addressing this issue as
follows:

a.) the USDA excellent 2010 Nutrition Guidelines although reflecting plant protein sources in the
“Food Pyramid” and accommodating the Vegetarian Diet, fails to reflect "the great pathophysiological
ramifications of bile acid metabolism” of the Omnivorous Diet;

b.) although the USDA in 2006 tried to end the federal government monetary subsidies to the
meat and restaurant industries in their annual spending of $60 Billion in media advertisements to consume their
Omnivorous Diet products, they failed to win the US Supreme Court suit against it brought by these industries
calling such subsidy curtailment as “unconstitutional”; and

c.) the FDA requires cholesterol, saturated fat and trans-fat ingredient quantification on
labels but has totally ignored "the great pathophysiological ramifications of bile acid metabolism” and the
research that indicates Dietary Cholesterol is treated as a poison by the human liver and itself is mutagenic and
carcinogenic.

The US Congressional Budget Office (CBO) of course to date is also in the dark as Congress about
this "National Security Health Issue Omission." As the US House of Representative Speaker Nancy
Pelosi (D, CA) has properly complained the CBO has failed to quantify a sickness prevention health
education and practice incentives cost saving which could help pay for at least 25% of the $2.5 Trillion
health bill projected for 2009 and the entire cost of Health Care Reform.

Thus the $600 Billion herein crudely estimated that could be saved annually by 2012 if the public were
told the truth about the "mysterious" and inexplicable annual continual rising of health expenditures in
America, and the truth about the continued less than average performance of the best outfitted and
instructed health professionals in the world; the health care crisis here in America would be addressed
by a Legislation that is self funding.

In this approach of assessing and valuing the health care expenditure savings to accrue annually in
America with a sickness prevention education and practice incentive program properly implemented
acknowledging "the great ramifications of dietary cholesterol and bile acid metabolism" the
Legislation would be self funding the first decade beyond the $190 billion in savings the CBO
acknowledges in the second decade.

It is contended that If the CBO had such sickness prevention health education and practice
incentives cost savings knowledge and figures then wise and humanitarian US Senators like my US
Senate representative US Senator Richard Lugar (R, IN.) and other humanitarian US Congresspersons
who presently oppose this health care reform movement would be in support of the need to end this
suppressed health care crisis. The November 2, 2009 New York Times newspaper article entitled
“Obama Strategy on Health Legislation Appears to Pay Off” states the following on the lack of
bipartisan support:
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications” of the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 59

“The No. 3 Republican in the Senate, Lamar Alexander of Tennessee, who attended one session with the
president, recalled that in the 1960s, when he was a Congressional aide, Democrats and Republicans worked
together on civil rights. He said he saw no possibility of a bipartisan health bill. ‘White House officials don’t
want one or don’t know how to do one,’ Mr. Alexander said.’”

Ideally, in order to enroll bipartisan support that is essential in properly implementing the just passed
Legislation spanning 10 years it had been suggested that as soon as possible a bipartisan US Select
Committee on Human Nutrition and Human Needs (Committee) be convened and/or a US House of
Representative Hearing; e.g. of the House Ways and Means Committee, behind closed doors to allow
for full candid professional and economic freedom to address this complicated and controversial issue of
"the great pathophysiological ramifications of dietary cholesterol and bile acid metabolism" and
shame the opponents of the 2010 Health Care Reform Legislation.

Minimally two weeks would be needed for the now proposed White House Office of Health Care
Reform to hold a Forum on American Maternal and Infant Mortality Etiology and Possible
Solutions initial session using audio-video conferencing with 1 week for planning and the second week
for testimonies. Besides confirming "the great pathophysiological ramifications of bile acid
metabolism" and its role in the resulting Dietary Cholesterol and Related Diseases and Syndromes
(DCRDS), the objectives of the Forum would be to establish the existence of the cited issue omission
and the savings from a sickness prevention education and practice incentive program in the nation’s
health expenditures.

Such a Forum by definition must have staff consultation that is balanced in its medical epistemological
makeup because of the allopathic medical complex's suppression of "the great pathophysiological
ramifications of dietary cholesterol and bile acid metabolism" and the great power of the health care
industry corporate members who have so suppressed this medical iconoclastic knowledge for over 70
years as follows:
a.) Allopathic Medical Doctors (MD's)
b.) Osteopathic Physicians
c.) Chiropractors
d.) Naturopaths
e.) Medicinal Herbologists
f.) Nutritional Herbologists
g.) Homeopaths

International leaders in the medical sciences and health advocates who are aware of "the great
pathophysiological ramifications of dietary cholesterol and bile acid metabolism" must be identified
and enrolled to testify in the suggested Committee and /or Hearing's deliberations; e.g. including:

1.) Makoto Makishima, PhD., Professor, Department of Biochemistry, Nihon University School of Medicine,
Tokyo, Japan cited above;
2.) Dr. Barbara Starfield, MD., DPH. Professor of Public Health, Johns Hopkins School of Hygiene and
Public Health in Baltimore, MD cited above;
3.) Dr. Dean Ornish, MD., CEO of the Preventive Health Research Institute, Inc., Sausalito, CA. cited above;
4.) Dr. Andrew P. Wilper, MD., MPH, University of Washington Medical School, Seattle WA. cited above;
5.) Dr. Steffie Woolhandler, MD. Professor of Medicine at Harvard University, Cambridge, MS. cited above;
6.) Arthur Ullian, CEO, National Center for Spinal Cord Injuries cited abov
7.) Dr. J. H. Weisburger, PhD.; and
8.) Dr. Neal D. Barnard. MD.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications” of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” ___________________________________ p 60

This Purple Seal invalidates the belief historically held by the Congressional Budget Office (CBO) and
many health care industry and news media economic analysts like distinguished economic journalist
David Hogberg of Investor’s Business Daily whose 10/16/09 article “Preventive Medicine Unlikely
To Curb Health Care Spending” concludes that any proposed Health Care Reform Legislation’s
prevention medical component would not generate the expected health care expenditure savings but
instead would lead to further deficits. These medical economic analysts are confused by failing to make
the health care distinction between:

1.) the relatively expensive allopathic medical strategy of "preventive medical services delivered by health
care providers based on costly tests and screenings targeting identifying diseases in their early stages; and

2.) the relatively inexpensive public health strategy of "sickness prevention education & practice incentives"
targeting the dietary life style changes that prevent the cited chronic diseases and syndromes from ever
starting.

Consequently, the 10/16/2009 Investor’s Business Daily article by the astute economist journalist David
Hogberg entitled “Preventive Medicine Unlikely To Curb Health Care Spending” quotes the CBO and
others who predict that the “preventive medicine” features of the Legislation will end up costing more
money than it saves. Clearly, they are confused about the distinction and differences between the
relatively expensive allopathic medicine “preventive health” strategy of tests and screenings and the more
cost effective and the cost efficient public health “preventive sickness” strategy of “sickness prevention
education and practice” toward the objective of avoiding the etiologic ingestion of Dietary Cholesterol
and associated Animal Fat and Animal Protein foods and the body cleansing of their pathogenic
supporting residues.

The former “preventive health” strategy of tests and screenings can indeed generate significant service
delivery expenses, while the latter “preventive sickness” strategy of “sickness American prevention
education and practice” is dependent on voluntary life style changes in diet and personal hygiene and
is cost efficient and cost effective.

Again, instead of the previously requested US Senate Committee and/or US House of Representative
Hearing this Purple Seal now proposes that the White House Office of Health Care Reform hold a
Forum on American Maternal and Infant Mortality Etiology and Possible Solutions moderated ideally
by Dean Ornish, MD., Director, Prevention Health Research Center or physician with his knowledge of
the cited issue omission to address the complicated and controversial etiological roles of Dietary
Cholesterol and Bile Acid Metabolism. As shown above the proper implementation of the Legislation
with an appropriate “sickness prevention education and practice incentive” component that reflects the 70
year suppression of the Health National Security Issue” of "the great pathophysiological ramifications
of dietary cholesterol and bile acid metabolism" is projected to be able to deliver $600 billion in health
care expenditure savings annually.

XIV. Conclusion

The human body's life expectancy potential of 130 years is referred to in the Bible Genesis 6, it is simulated
by computers as in the 1980's Tucson Arizona Biosphere Projections and it has been esoterically enjoyed for
over two millennium by the people of Hunza Province, Pakistan whose lifestyle is summarized in
Appendix G and detailed on http://www.theuniversityofgod.org/Page12.org.

As the legendary fitness trainer Jack Lalanne (1914-20110 who died at 96 has shown on TV for
decades Centurion healthy and active lives can be attainable by those Americans rich and poor who
can transcend the Western civilization's cultural diet of “meat and potatoes” properly recognizing and acting
upon this suppressed knowledge of "the great pathophysiological ramifications of dietary cholesterol
and bile acid metabolism." His use of freshly juiced fruits and vegetables is the cornerstone of
“nutritional herbology” and longevity. His failure to cleanse his past Omnivore diet residues mostly
fish and eggs lead to heart surgery 4 years ago and then finally death by pneumonia.

It is no coincidence that the Ancient Egyptian/Kemitian School of On (Annu), the Hebrew and proto-Christian
Bible Genesis 1: 29 on the aboriginal "Human Dietary Instructions" and the Jain and Hindu religions of Asia
India present the vegan/vegetarian diet as the standard for ideal human dietetics.

The Japanese society already enjoying an 92 year average life span compared to the 78 years of America
are targeting this goal of increasing their longevity further having fostered the May, 16, 2002 Science
Magazine article "Vitamin D receptor As an Intestinal Bile Acid Sensor" and societal taking actions
to curb any further the penetration of the American high fat diet into Japan. However, Japan will not
achieve an increase in LE unless it curbs its ingestion of ocean and fresh water aquatic sourced Dietary
Cholesterol which is the cause of its high heart disease rates.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications” of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” ___________________________________ p 61

AARP Legislative Director John Rother in the above cited September 7, 2009 Los Angeles Times article
by Journalist Janet Hooks entitled "Health-care reform: Could a smaller dose work?" carried by the
Indianapolis Star and is quoted about the US. Senate health care reform bipartisan leadership with the
August 25, 2009 death from brain cancer of Senator Edward Kennedy (D, MA):

"It is hard to look at the Senate and see anyone who has the same ability to
conceptualize the big picture. But we hope someone will step forward and take the role."

“Universal health insurance” for all Americans via private insurance plans and a “public option” is
more than “affordable (deficit neutral)” when "the great pathophysiological ramifications of dietary
cholesterol and bile acid metabolism" are properly addressed and the resulting health cost reduction
from proper sickness prevention health education and incentive practice; the savings of lives is
extrapolated for increased income; tax payments of a healthier, productive longer living and increased
population are manifested and factored in.

In this regard the October 24, 2009 New York Times ongoing series Prescription: Making Sense of the
Health Care Debate featured a brilliant interview of Mr. Arthur Ullian, President of the Boston, MA. based
National Council on Spinal Cord Injuries, Inc. entitled “Universal Coverage: A Revenue Windfall?” by
freelance journalist Anne Underwood. It highlights his upcoming analysis in the Proceedings of the
National Academy of the Sciences on the economic benefits of the proposed Health Care Reform
Legislation which by 2020 his R & D team projects would such increase the Nation’s tax revenues by
$312 Billion a year and generate $242 Billion in Medicare expense savings annually for a total
$1.457 Trillion by 2030! The threat of future deficits from the perennial rising costs of the federal
Medicare and Medicaid would be ameliorated permanently.

It is possible that the best health care system in terms of training, diagnostic, emergency, reconstructive
and surgical parameters and definitely the most expensive medical complex in the world in America could
produce for all its people from rich to poor a health status of reduced maternal and infant mortality,
decreased chronic diseases and syndromes of the Dietary Cholesterol and Related Diseases and
Syndromes (DCRDS) and extended life expectancy for far less money than being spent presently and
projected to be spent in the future? Yes, if the Purple Seal is broken and the truth about the the Great
Law of Vegan Human Nutrition reflecting the human vegan genetic genome is promulgated to all.

Again the National Security of America’s socio-political economic leadership it now enjoys in the world
is being threatened not by terrorism or a nuclear or conventional military threat but from within as the
ancient Roman Empire and Great Britain’s 20 th Century hegemony fell from within in large part from
ignoring the "the great pathophysiological ramifications of dietary cholesterol and bile acid
metabolism.”

Specifically, the combined effects of the sudden appearance over the last 30 years of Metabolic
Syndrome affecting 24% of Americans involving simultaneously 9 risk factors for obesity, diabetes
mellitus, hypertension, and coronary vascular heart disease [increased waist circumference, elevated
blood triglycerides, low blood HDL cholesterol, high blood LDL cholesterol, high blood uric acid,
high blood pressure, fasting blood glucose, increased blood coagulation and in women high
androgen levels and in me high estrogen levels] and the proliferation of the Dietary Cholesterol and
Related Diseases and Syndromes (DCRDS) are already visible with 75% of the nations youth unfit for
military service and 65% of Americans overweight or obese.

The free lance journalist Andrea Stone recently reported 11/03/2009 on www.sphere.com that America’s
military recruiters have declared that 75% of the American youth are unfit for military service because of
overweight and obesity, mental neurosis including drug and alcohol abuse and prison records. It is clear
that the Omnivore Diet generating the chronic diseases and syndromes including the latest
manifestation of Metabolic Syndrome is the cause of this Health National Security crisis.

“Tell me what you eat and I will tell you what you are … The destiny of a people depends on the
nature of their diet”
18 th Century French Political Economist Brillat-Savarin

To continue to allow Special Interest profiteering to cover up the real cause of the chronic diseases
and syndromes that have gripped the American people with obesity and sickness and consume 65% of
America’s annual health care expenditures in 2009 estimated at $2.5 Trillion by the daily ingestion of
dietary cholesterol and its related animal fat and protein residues is not only unpatriotic and
immoral but is biomedically insanitary and societally insane and clearly a National Security threat.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications” of the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 62

Ideally, the just passed “nearly universal insurance coverage” based Health Care Reform Bill will be
implemented:

1.) with proper provision for a sickness prevention education and practice incentives implementation
with priority insurance premium discounts for those documenting they are on a vegan diet and with a
lesser premium discount for those documenting they are on a vegetarian diet; and

2.) with bipartisan US Senate and US House of Representative support as opponents are educated
and shamed on their ignorance of the cited effects of the “health national security issue omission.”

Only such federal government investigation and federal health care system implementation will end
the literal “blood sucking” of the American people and "legal theft" of its tax dollars paying for an overpriced,
inefficient and ineffective and thus over rated national health care system.

XV. DEDICATION and CERTIFICATION

Let it be resolved that this Purple Seal is dedicated to my mother Sarah Louise Ervin Hall (Indianapolis,
IN.) who died of Iatrogenic Disease and in Iatrogenic Poverty on my last birthday 1/13/2010.

1997 Paulownia "supertrees" after 3 month's growth at the Indianapolis, IN. PrototypeSAF Garden
Site with Project Benefactor Louise Ervin. Hall and her son Project Director George W. Singleton III.

Sarah Louise Ervin Hall was a major BRCA, Inc. financial backer for over 20 years. This and her
motivational advice “not to give up” resulted in this “state of the art” socio-political economic, chronic
disease and syndrome etiological RD & D document analysis and synthesis, using proprietary General
Human Systems Theory (GHST) and Nutritional Herbology multidisciplinary investigative analysis.

Since my Mother died a victim of Iatrogenic disease and Iatrogenic poverty and it is the goal of the
series of White/Blue/Red/Green Papers and now the Purple Seal to end the grip of chronic diseases
and syndromes on America and the world identified herein as the preventable “Dietary Cholesterol
and Related Diseases and Syndromes (DCRDS);” it is appropriate that the suppressed “great
ramifications of dietary cholesterol and bile acid metabolism” and their etiological role be finally
exposed and documented.

Whereas it took approximately $540,000 in BRCA, Inc. resources earmarked from the 2007 European
Union Humanitarian Grant to research synthesize, develop and publish this Purple Seal begun over a
year ago on January 15, 2009 in support of the “universal health insurance” and health care reform
legislative initiative of the US President Barack Obama’s Administration in the US Congress.

This work has been conducted from a tent publishing HDQ under a bridge in Indianapolis, IN.
because of the demonically inspired Special Interests who since before Jesus Christ oppose
and persecute the Rastafarian knowledge and technology of the Ancient Egypt/Kemit “School of
On (Annu or God).” Since March 14, 2007 reception of the 2.3 M Euros 2007 European Union
Humanitarian Grant (EUHG) gift to pay the fee and award letter these funds have been blocked by
reactionary American and Great Britain public and private elements officially protested to the
Geneva, Switzerland located United Nations Office of the High Commissioner for Human Rights
on November 5, 2010 documented on http://www.theuniversityofgod.org/Page22.html that follow.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications” of the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 63

Consequently, the over $540,000 in resources to produce the Purple Seal have been “negatively
financed” and the level of suffering accommodated because my physical wife BRCA, Inc. High
Priestess Elizabeth Mensah Singleton of Ghana encourages me to endure with her love, prayers,
meditations and words of encouragement.

Date: 6/07/2011

State of the World Forum Member # 20827


2007 and 2009 European Union Humanitarian Grantee

http://www.theuniversityofgod.org/Page18.html
gws@theuniversityofgod.org

Nora Public Library


Indianapolis, IN. USA
(Franz Lewis, 2009)

Copyright: This Purple Seal and previous White Paper, Blue Paper, Red Paper and Green Paper are
copyrighted and allows for up to 9 authorized copies by the user to be made and requiring proper citation to it
and its references to be non- violated by the user.

The White/Blue/Red/Green Papers are the precursors to the BRCA/Enlightenment Publications, Inc. e-book THE
PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological Ramifications of
the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in the Aboriginal Vegan Genotype Human Body.

Acknowledgement: Documentation and images from www.wikipedia.org.


Acknowledgement: Documentation from Encyclopedia Britannica.
Acknowledgement: Documentation citations go to The Cancer Project, Inc. at www.cancerproject.org.

A Complementary copy of the Purple Seal precursor Green Paper is available for download from
http://www.theuniversityofgod.org/Page8.html.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” _________________________________ p 64

XVI. Bibliography
A. Synthesis of Research & Development Methodology

1.) Singleton, George W., et al, Evaluation of Rural Health Research, Vol. I, II, & III; 1975.
Funded by the US Department of Agriculture, Office of the Secretary.
Retrievable from the U.S. Department of Commerce’s National Technical
Information System (NTIS) and the National Education Association (NEA)
Education Research Information Center (ERIC)

2.) Singleton, George W., General Human Systems Theory (GHST): Detailed Chronic Poverty Systems Analysis
[Flow Chart #1] 12/09/2004 linked on http://www.theuniversityofgod.org/Page7.html

B. Religious, Spirituality and General Human Systems Theory Texts


(by last name alphabetical)
1.) Blavatsky, Madame, Isis Unveiled, 1972

2.) Blavatsky, Madame, Secret Doctrine, 1972

3.) Budge, E. Wallis, Chapters of Coming Forth By Day, The Full Theban Recension of Egyptian Book
of the Dead, 1898

4.) Campbell, T. Colin; Campbell II, Thomas M.; Lyman, Howard, The China Study: The Most Comprehensive
Study of Nutrition Ever Conducted and the
Startling Implications for Diet, Weight Loss
and Long-Term Health, 2006

5.) Diop, Chek Anka, African Origin of Civilization: Myth or Realty, 1974

6.) Eisler, Riane, The Chalice and the Blade: Our History, Our Future, 1988

7.) Daniel, Bible: Book of Daniel (King James Version)

8.) Freud, Sigmund, Moses and Monotheism, 1939

9.) Hamaker, John and Weaver, Donald, The Survival of Civilization, 1982

10.) Hancock, Graham and Bauval, Robert, The Message of the Sphinx:
A Quest for the Hidden Legacy of Mankind, 1996

11.) Herodotus, The History of Herodotus, Bk. I & II, 1956

12.) Hoffman, Jay Milton., Hunza: 15 Secrets of the World's Healthiest and Oldest Living People, 1985
[synopsis extract of as Appendix G]

13.) Hotema, Hilton, The Great Law, 1962

14.) James. George, Stolen Legacy, 1976.

15.) Kellogg, John Harvey, The Natural Diet of Man, 1923

16.) Kulvinskas, Viktoras H., Survival in the Twenty First Century: Planetary Healers Manual, 1975

17.) Macko, SA, et al, FASEB J, V. 13 (3), pp_559-62, 1999

18.) Manetho, History of Egypt/Pharonic List, 1954

19.) Moses, Bible: Genesis (King James Version)

20.) Osman, Ahmed, Moses and Akhenaten, 1990

21.) Petrie, Flinder, Abydos II, 1903

22.) Petrie, Flinder, Prehistoric Egypt, 1920

23.) Plato, Timaeus, 1954.

24.) Ravenscroft, Trevor, Spear of Destiny, 1974

25.) Reed, Douglas, The Controversy of Zion, 1954


THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” _________________________________ p 65

XIII. Bibliography (continued)


26.) Robinson, Editor, Nagamaddi Bible, 1976

27.) Saunders, Kerrie A., The Vegan Diet As Chronic Disease_Prevention:


Evidence Supporting the New Four Food Groups, 2003

28.) Schoch, Robert, “A Modern Riddle of the Sphinx, “ Omni, Aug. 1992, 14:46-48

29.) Shanks, Hershel, Understanding the Dead Sea Scrolls, 1993

30.) Singh, Kirpal, Crown of Life, 1961

31.) Sominer, A. Dupont, The Essene Writings from Qumran, 1959

32.) Szekely, Edmond, Essene Gospel of Peace, Bk. I. International Biogenic Society. 1981.

33.) Szekely, Edmond, Essene Gospel of Peace, Bk. IV. International Biogenic Society. 1981.

34.) Szekely, Edmond, The Essenes by Josephus and His Contemporaries, Academic Books, 1976.

35.) Szekely, Edmond, The Essene Way: Biogenic Living, International Biogenic Society. 1986

36.) Tompkins. Peter, Secrets of the Great Pyramid, 1978

36.) Tompkins, P. and Bird. C., Secret Life of Plants, 1989

38.) Tompkins, P. and Bird. C., Secrets of the Soil: New Solutions for Restoring Our Planet, 1998

39.) West, John A., "Civilization Rethought” in Conde Nast, February, 1993

40.) Singleton, George W., The Egyptian Mystery “School of On (God or Annu)”: Esoteric Atannuology,
Egyptology & Rastafariology, Vol. 1, 2005 __ free 2 part e-Book download link on
http://www.theuniversityofon.org/Page3c.html

C. Nutritional Herbology Texts and Treatises


(by last name alphabetical)
1.) Ehret, Arnold, Mucusless Diet Healing System, 1934

2.) Ehret, Arnold, Rational Fasting, 1930

3.) Fathman, George and Doris, Live Foods, 1973

4.) Kadans, Joseph M., Encyclopedia of Fruits, Vegetables, Nuts and Seeds for Healthful Living, 1975

5.) Kellogg, John Harvey, The Natural Diet of Man, 1923

6.) Kloss, Jetro, Back to Eden, 1939

7.) Walker, Norman Wardhaugh (N.W.), The Vegetarian Guide to Diet and Salad, 1971

8.) Walker, N.W., Colon Health: The Key to a Vibrant Life, 1977

9.) Walker, N.W., Fresh Vegetable and Fruit Juices: What’s Missing in Your Body, 1978

10.) Walker, N.W., Become Younger, 1949


Note: N.W. Walker lived to be 99 ½ years just missing his Centurion goal.

11.) Stephan Walsh, Plant Based Nutrition and Health, 2003

12.) Young, D. Gary, People’s Desk Reference for Essential Oils, First Edition, 1999 [Appendixe J]

13.) Singleton, George W, Original Prevention of Sickness: General Nutrition Instructions, 1997, rev. 2005
[Appendixes H-1, H-2] __ free e-Book download link on http://www.theuniversityofgod.org/Page8.html

D. Public Health, Epistemology and Epidemiology


(by earliest to recent publishing date)

1.) Ellis, F.R. et al, “The Nutritional Status of vegans and vegetarians”
Symposium Proceedings of the Nutritional Society, V. 26, pp 205-11, 1967
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” _________________________________ p 66

XIII. Bibliography (continued)


2.) Burkitt, DP, “The Etiological Significance of Related Diseases”
Canadian Family Physician, V. 22 pp 63-71, 1976

3.) Starfield, Barbara, "Is US Health Really the best in the world?"
Journal of the American Medical Association (JAMA), July 26, 2000

4.) Stoneham M, et al, “Olive oil, diet and colorectal cancer: an ecological study and a hypothesis”,
J Epidemiology of Community Health. 54(10) pp. 756-60, October, 2000

5.) Meessen, Bruno, et al, “Iatrogenic Poverty” editorial


in Tropical Medicine and International Health Journal, 8 (7) pp. 581- 4, July, 2003

6.) Chao, Ann, et al, “Meat Consumption and Risk of Colorectal Cancer,
JAMA, V. 293, pp 172-82, January, 2005

7.) Norat, Teresa, et al, “Meat, Fish and Colorectal Cancer Risk: The European Prospective Investigation into
Cancer and Nutrition,” Journal of the (British) National Cancer Institute, V. 97 (12),
pp. 906-16, June, 2005

8.) Beliveau, Richard and Gingras, Denis, “Role of Nutrition in Preventing Cancer”,
Canadian Family Physician, V. 53 (11), pp 1950-11, 2007

9.) Ornish, D., et al, ”Intensive lifestyle changes for reversal of coronary heart disease”
JAMA, 1998, 280: 2001- 2007

10.) Barnard, Neal D., et al, Program for Reversing Diabetes: The Scientifically Proven System fo Reversing
Diabetes without Drugs, 2008

11.) Reis, JP, et al, “Low vitamin D levels associated with several risk factors in teenagers”
presented at American Heart Association 49 th Conference, March 11, 2009

12.) Sinha, Rashmi, et al, “Meat Intake and Mortality”


Archives of Internal Medicine, V. 169, No. 6, March 23, 2009

13.) Craig, W. J., et al, “Health Effects of Vegan Diet”


American Journal of Clinical Nutrition, V. 89, No. 5 May 2009

14.) Ornish, Dean, “Mostly Plants” editorial in


[Appendix E] American Journal of Cardiology (AJC), May, 2009

15.) Kleiner, Susan M. “Is it Hip and Healthy to be Vegan?”


Fitness Rx Magazine linked at
http://www.powereating.com/topic-of-the-month/index.php, 2009

16.) Wilper, Andrew P., et al, “Health Insurance and Mortality in U.S. Adults”
published on line and to be printed in the American Journal of Public Health,
Vol. 99, Issue 12, December, 2009

E. Cholesterol Metabolism Research


(by earliest to recent publishing date)
1.) Kennaway, E. L. and Hieger, I, “Carcinogenic Substances and their Fluorescence Spectra,”
British Medical Journal, V. 1 (3662), 1930, pp. 1044 - 46

2.) Hieger, Izrael “The Spectra of Cancer Producing Tars and Oils and Related Substances,”
Biochemical Journal, V. 24 (2), pp. 505-61, 1930

3.) Hieger, Izrael, “Carcinogenic Substances in Human Tissue,”


Cancer Research, V 6, pp 657- 67, 1946

4.) Hieger, Izrael, “Carcinogenic Activity of preparations rich in Cholesterol,”


Nature, V. 160, pp 270- 71, 1947

5.) Hieger, Izrael, “Carcinogenic Activity of Lipoid Substances,”


British Journal of Cancer, V. 3, pp 123-39, 1949

6.) Fieser, Louis Frederick and Fieser, Mary, Natural Products Related to Phenanthrene,
(American Chemical Society Monograph No. 70),
Reinhold Publishing, NY., 1949
Note: Cited by A. Lacassagne in Nature magazine, 1966 V 209 p 1026
on his and others research on female sex hormone Estrogen being carcinogenic.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” _________________________________ p 67

XIII. Bibliography (continued)

7.) Fieser, Louis Frederick and Fieser, Mary, excerpts from the Natural Products Related to Phenanthrene,
(American Chemical Society Monograph No. 70),
The Journal of the American Medical Association, V. 142, No. 11,
pp 858, March 18, 1959

8.) Fieser, Louis Frederick, “Some Aspects of the Chemistry and Biocjemistry of Cholesterol,”
Science, V. 119, pp 710, 1951

9.) Hieger Izrael, and Orr, S.F.D., “On the Carcinogenic Activity of Purified Cholesterol,”
British Journal of Cancer, V. 8 (2), pp 274-90, 1954

10.) Hieger, Izrael, “Cholesterol as a Carcinogen,”


Proceedings of the Royal Society, B (Biological Sciences), V. 147, pp 84-89, 1957

11.) Hieger, Izrael, “Cholesterol Carcinogenesis,”


British Medical Bulletin, V. 14, pp 159-160, 1958

12.) Hieger, Izrael, “Carcinogenesis of Cholesterol,”


British Journal of Cancer, V. 8 (3), pp 439-51, 1959

13.) Hieger, Izrael, (Unknown article title)


Acta Unio Internationalis Contra Cancrum, V. 15, p. 603, Geneva, Switzerland, 1960

14.) Hieger, Izrael, Carcinogenesis,


Academic Press, London, England, 1961

15.) Mercer, EI and Glover, J, “The Interconversion of Cholesterol, 7-Dehydrocholesterol and Lathosterol in the Rat,”
Biochem J., V. 80, pp 552-, 1961

16.) Hieger, Izrael, “Cholesterol as Carcinogen_ I. Sarcoma Induction by Cholesterol in a


Sensitive Strain of Mice,” British Journal of Cancer, V 16 (4) pp 716-21, 1962

17.) Nair, Padmanabhan P., “Role of Bile Acids and Neutral Sterols in Carcinogenesis,
American Journal of Clinical Nutrition, V 48 (3), pp 768-74, 1988

18.) Westover, EJ and Covey, DF, “The Enantiomer of Cholesterol,


J Membrane Biol., V 202, pp 61-72

19.) Xu, Fang, et al, “Dual Roles for Cholesterol in mammalian cells,”
Proceedings of the National Academy of Sciences, V 102 (41), pp 14551-56, 2005

F. Bile Acid Metabolism Research: Adult Human


(by earliest to recent publishing date)

1.) Cook, JW, Kennaway, EC, Kennaway, NM, “Production of tumors in mice by deoxycholic acid”,
Nature, 145, pp 627, 1940

2.) Samuelsson, B. “Bile Acids and Steroids: On the mechanism of the


biological formation of deoxycholic acid from Cholic Acid,”
Journal of Biological Chemistry, V. 235, 361, No. 2, February, 1960

3.) Lacassagne, A., Buu-Hoi, NP, Zajeda, F. “Carcinogenic activity of apolcholic acid”,
Nature, 190, pp1007-8, 1961

4.) Gustafsson, B., E., et al, “Isolated fecal microorganisms capable of 7-alpha dehydroxylating bile acids,”
Journal of Experimental Medicine, 123: 413, 1966

5.) Sauter, G. et al, ”Formation of cholic acid and chenodeoxycholic acid from 7-alpha hydroxycholesterol
and 27- hydroxycholesterol by primary cultures of human hepatocytes,”
Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Matabolism,
V. 1300, Issue 1 pp 25-29, March, 1966

6.) Hill, MJ, et al, “Degradation of bile salts by human intestinal bacteria,”
Gut Journal, V. 9, pp 22-27, September, 1968

7.) Aries, Vivienne C., et al, “Degradation of bile salts by human intestinal bacteria,”
Gut Journal, V. 10, pp 575-76, 1969

8.) Aries, Vivienne C., et al, “Bacteria and aetiology of cancer of the large bowel,”
Gut Journal, V. 10, pp 334-35, 1969
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 68

XIII. Bibliography (continued)


9.) Aries, Vivienne C. and MJ. Hill, “The formation of Unsaturated Bile Acids by Intestinal Bacteria,”
Proceedings of the Biochemical Society, V. 119, pp37-38, 1970

10.) Aries, Vivienne, C. and Hill, M.J. “Degradation of Sterods by Intestinal Bacteria II,”
Biochem, Biophys Acta, V. 202, pp. 535, 1970

11.) Aries, Vivienne, C., et al, “The effect of a strict vegetarian diet on the faecal flora and faecal steroid concentration,”
British Journal of Pathology, V. 103, pp 54-56, 1971

12.) Hill, MJ et al, “Bacteria and aetiology of cancer of large bowl”,


Lancet, 1: 95, 1971

13.) Midtvedt, Tore,MD., “Microbial bile acid transformation”,


The American Journal of Clinical Nutrition, V. 27, pp 1341- 1347, November, 1974

14.) Lavy, U., et al, “Bile acid synthesis in man: II. Determination of 7-alpha-hydroxycholesterol, (22R)-22-
hydroxycholesterol, and 26-hydroxycholesterol in human meconium,”
J. of Lipid Research, V. 18, pp 232-238, 1977

15.) Uchida, K. et al, “Effect of dietary cholesterol on cholesterol and bile acid metabolism in rats,”
Japanese Journal of Pharmacology, 27 pp 193-204, 1977

16.) Fedorowski, T, et al, “Transformation of chenodeoxycholic acid and ursodeoxycholic acid by


human intestinal bacteria”, Gastroenterology J., 77 (5) pp. 1068-73, November, 1979

17.) Ayaki, Y. et al, “Role of endogenous and exogenous cholesterol in liver as the precursor for bile acids in rats,”
Steroids, 38 (5) pages 495-509, November, 1981

18.) Hirano, S, et al, “In vitro transformation of chenodeoxycholic acid and ursodeoxycholic acid by human
intestinal flora, with particular reference to the mutual conversion between the two bile acids”,
Journal of Lipid Research, V. 22, pp. 735-743, 1981

19.) Kaul, HK, et al, “Genotoxicity of 2 fecal steroids in murine colonic epithelium assessed by sister chromatid
exchange technique, “ Mutagenesis, V 2 (6) pp 441-44, 1987

20.) Owen, RW et al, “Biological transformations of Bile acids by Clostridium”


Journal of Microbiology, V 30., pp 233-38, 1985

21.) Sylvestor, PW, et al, “Comparative effects of different animal and vegetable fats fed before and during
carcinogen administration on mammary tumorigenesis, sexual maturation, and
endocrine function in rats”, J. Cancer Research, 46 (2) pp 757-62, Feb, 1986

22.) Owen, R.W. et al, “Fecal steroids and colorectal cancer”,


Journal of Nutrition and Cancer, 9 (2-3), pp. 73-80, 1987

23.) Korpela, JT, et al, “Fecal free and conjugated bile acids and neutral sterols in vegetarians, omnivores, and
patients with colorectal cancer”, Scandinavian J. Gastroenterology, 23 (3) pp 277-83, April, 1988

24.) Nair, Padmanabhan, P., “Role of bile acids and neutral sterols in carcinogenesis”,
American Journal of Clinical Nutrition, 48, pp 768-74, 1988

25.) Rao, AV, et al “The role of dietary phytosterols in colon carcinogenesis”,


J. Nutrition and Cancer, 18 (1) pp. 43-52, January, 1992

26.) Bayerdorffer, Ekkehard, et al, “Decreased High-Density Lipoprotein Cholesterol and Increased Low-Density
Cholesterol Levels in Patients with Colorectal Adenomas”,
Annuals of International Medicine, V. 118 (7), pp. 481-487, April 1, 1993

27.) Reiss, AR, et al, “Sterol 27-hydroxylase: high levels of activity in vascular epithelium,”
J. of Lipid Research, V. 35, pp. 1026-1030, 1994

28.) Hamada, K, et al, “In vitro formation of DNA adducts with bile acids”,
Carcinogenesis, V 15 (9) pp. 1911-1915, 1994

29.) Javett, Norman B. “Bile Acid Synthesis from Cholesterol: Regulatory and Auxiliary Pathways,”
NY University Medical Center, NYC, NY, 1994

30.) Nagengast, F.M., et al, “Role of bile acids in colorectal carcinogenesis,”


European Journal of Cancer, V. 31, Issue 7, pp. 1067-1070, April, 1995
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” _________________________________ p 69

XIII. Bibliography (continued)

31.) Peter JH Jones, et al, “Dietary Cholesterol Feeding Suppresses Human Cholesterol Synthesis Measured by
Deuterium Incorporation and Urinary Mevalonic Acid Levels”
Journal of Arteriosclerosis,Thrombosis and Vascular Biology
(American Heart Association) V 16, pp 1222-28, 1996

32.) Kishida, T, et al, “Analysis of bile acids in colon residual liquid or fecal material in patients with colorectal
neoplasms and control subjects,” J. Gastroenterology, 32 (3), pp 306-11, June, 1997

33.) Ogawa, A. et al, “Lithocholic Acid, a Putative Tumor Promoter Inhibits Mammalian DNA Polymerase Beta”,
Japanese Journal of Cancer research, V. 84, Issue 11, pp. 1154-1159, November, 1998

34.) Baijal, PK, et al, “Comparative effects of secondary bile acids, deoxycholic and lithocholic acids, on aberrant
crypt foci growth in the postinitiation phases of colon carcinogenesis,”
J Nutri. & Cancer, 31(2), pp 81-9, February, 1998

35.) Kozoni, V., et al, “The effect of lithocholic acid on proliferation and apoptosis during the early stages of colon
carcinogenesis: differential effect on apoptosis in the presence of a colon carcinogen,”
J. of Carcinogenesis, V. 21, No 5 pp 999-1005, May, 2000

36.) Makishima, Makoto, PhD, et al, “Vitamin D Receptor as an Intestinal Bile Acid Sensor,”
[Appendix C] Science, May 17, 2002

37.) Ornish, D. “Statins and the soul of medicine”, editorial,


Am Journal of Cardiology, V. 89, pp. 1286-1290, June, 2002.

38.) Tabas, Ira, “The Pathophysiology of Cholesterol”, in Cholesterol in Health and Disease Issue,
J. Clin. Investigation, V. 110, pp 583-90, 2002

39.) Debruyne, PR, et al, “Bile Acids stimulate invasion and hapatotaxis in human colorectal cancer cells through
activation of multiple oncogenic signaling pathways,” Oncogene, 21 pp. 6740-50, 2002

40.) van Faassen, A, et al, “Serum bile acids and risk factors for colorectal cancer,”
British Journal of Cancer, V. 90, pp 632-34, 2004

41.) Soma, T., et al, “Chenodeoxycholic acid stimulates the progression of human esophageal cancer cells: A
possible mechanism of angiogenesis in patients with esophageal cancer,”
Cancer, 15 (4), pp 771-82, 200641.) Shea, Heidi C, et al, “Analysis of HSD3B7 knockout
mice reveals that 3 alpha-hydroxyl stereochemistry is required for bile acid function,”
Proc. National Academy of Sciences, V. 104(28), pp 11526-33, 2007

42.) Skjelbred, CF, et al, “Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and
adenomas,” BMC Cancer. 7: 228, Dec 19, 2007

43.) Tong, Jin Lu, et al, “Association between Fecal Bile Acids and Colorectal Cancer: A Meta-analysis of
Observational Studies”, Yonsei Med J.; 49 (5): 792–803, October 3, 2008

G. Bile Acid Metabolism Research: Fetus, Neonatal, Infant, Child Human


(by earliest to recent publishing date)
1.) Marin, Jose, JG, et al, “Molecular basis of the excretion of fetal bile acids and pigments through the fetal liver-
placenta-maternal liver pathway,” Annals of Hepatology, V. 4 No. 5, pp 70-6, 2004

2.) Glantz, Anna, et al, “Intrahepatic Cholestasis in Pregnancy: Relationships Between Bile Acid Levels and Fetal
Complication Rates”, Hepatology J, V 40, No. 2, pp 467-74, 2004

3.) Glantz, Anna, et al, “Intrahepatic Cholestasis of Pregnancy: Amelioration of Puritis by UDCA is Associated with
decreased Progesterone Disulphates in Urine, Hepatology J, V 47, No. 2, 2008 pp 544-51

H. DNA and RNA Metabolism and Skin Color Mutations


(by earliest to recent publishing date)

1.) Cavalli-Sforza, Luigi Luca and W.F. Bodmer, The Genetics of Human Populations, 1977

2.) Valverde, P et al, “Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and
fair skin in humans”, Nat. genet, V 11, No. 3 pp 328-30, 1995

3.) Cavalli-Sforza, Luigi Luca, Genes, Peoples and Languages, ISBN 0140296026, 2001

4.) Wilford, John Nobel, “First Europeans bring a Mystery to New York,” New York Times, January, 10, 2003
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 70

XIII. Bibliography (continued)

5.) Cheng, Keith, et al, Science, V. 28, October, p. 601, 2005

6.) Lamason, RI, Cheng, KC, et al, “SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and
humans”, Science, 310, No. 5755, pp. 1782-6, December, 2005

7.) Norton, Heather L., et al, “Genetic Evidence for Convergent Evolution of Light Skin in Europeans & East Asians”
Oxford Journals [4] December 11, 2006
Mol. Biol. Evol. 24, 710-22, 2006

8.) Gibbons, Ann “European Skin Turned Pale Only Recently, Gene suggests”, American Association of Physical
Anthropologists Meetings, Science, V. 316, No. 5823, p. 364, April 20, 2007

9.) Myles, S. et al, Hum Genet., V 120, pp 613-21, 2007

10.) Ginger, RS, et al, “SLC24A5 encodes a trans-Golgi network protein with potassium-dependent sodium-
calcium exchange activity that regulates human epidermal melanogenesis”,
J. Biol. Chem., V. 283, No. 9, pp 5486-95

I. VITAMIN D3 RESEARCH AND DEVELOPMENT

1.) Garland F.C., "Do sunlight and Vitamin D reduce the likelihood of colon cancer?",
International Journal of Epidemiology, 1980; 9:277-231

2.) Garland F.C., "Serum 25-hydroxyvitamin D and colon cancer: 8-year prospective study",
Lancet, 1989; 2:1176-1178.

3.) Garland F.C., "Geographic variation in breast cancer mortality in the United States",
Preventive Medicine, 1990; 19:614-622

4.) Ainsleigh HG. "Beneficial effects of sun exposure on cancer mortality."


Preventive Medicine, 1993; 22;132-140.

5.) Garland F.C., E. Gorham "Biologic Effects of Light", 1993,


in E.G.Jung and M.F.Hollick eds. Walter de Gruyter, New York 1994, pp.509-516

6.) E.M.John, G.G.Schwartz and D.M.Dreon "Vitamin D and Breast Cancer Risk," Northern California Cancer Center,
'Era of Hope' Conference, Oct.31-Nov.4, 1997

7.) Fitzpatrick, James, John Aeling. "Dermatology Secrets in Color" Hanley & Belfus, 2001.

8.) Bikle, Daniel D. “UV radiation, Vitamin D and Epidermal Carcinogenesis”


from Expert Review of Dermatology posted 12/18/2009 www.medscape.com

J. Heliocobactor Pylori Bacteria

1.) Warren,J. Robin and Marshall, Barry J., “Unidentified curved bacilli on gastric epithelium in active
gastritis,” Lancet i: 1273-1275, 1983

2.) Marshall, B.J., et al, “Attempt to fulfill Koch’s postulates for pyloric Campylobacter,”
Med. J. Aust., V. 142 pp 436-39

3.) Marshall, B.J. et al, “Antibacterialaction of bismuth in relation to Campylobactor pyloridis colonization
and gastritis,” Digestion, V. 37,(Suppl.2):pp 16-30, 1987

4.) Hiral, Yoshhikazu, et al, “Unique Cholesteryl Glucosides in Heliocobactor pylori: Composition and
Structural Analysis”, J of Bacteriology, V. 177, No. 18, pp 5327-33, 1995

5.) Haque, Mahmudul, et al, “Lipid Profile of Heliocobactor spp.: Presence of Cholesteryl Glucosides as a
Characteristic Feature,” J of Bacteriology, V. 178, No. 7, pp 2065-70, 1996

6.) Kusters, Johannes G., et al, “Pathogenesis of Heliocobactor pylori Infection”,


Clinical Microbiology Reviews, V. 19, #3, pp 449-490, 2006
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolism of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in
the Aboriginal Vegan Genotype Human Body” __________________________________ p 71

XIII. Bibliography (continued)

K. Estrogen Metabolism

1.) Fieser, Louis F. and Fieser, Mary, “Influence of Estrogen on Carcinogenesis,” Natural Products Related
to Phenanthrene, pp 330-31, Reinhold Publishing, NYC, NY, Third Edition, 1949

2.) Lacassagne, American Journal of Cancer, V. 37, pp 414, 1939

3.) Loeb, Leo, “Estrogenic Hormones and Carcinogenesis,” J. Am. Med. Assoc., V. 104, pp. 1597, 1935
APPENDIXE A-1. The Aboriginal Diet of Humans (Homo Sapiens)

I. Ancient African, Eastern and Middle Eastern Cultures and Civilizations: “Golden Age”
[Vegan (No Animal Meat, Dairy Products or Meat) Diet]
II. Ancient European and North Asian Culture and Civilizations: “Mammal Cannibalism”
[Omnivore/Mixed Diet]
III. Origin of the Vegetarian Diets of Africa and Asia: “Accommodation”
[Lacto-Vegetarian (Dairy Products) Diet and Ovo-Lacto (Eggs and Dairy Products) Vegetarian Diet]
IV. Mitochondrial Eve, the Evolution of Homo Sapien and Great Law of Vegan Human Diet
PURPLE SEAL: BRCA, INC. MEMBERS AND DESIGNATED NETWORK
THE PURPLE SEAL:: Breaking the Animal Dietary Cholesterol and DNA Related Diseases and
Syndromes: “The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary
Cholesterol, Bile Acid, DNA & Protein in the Aboriginal Vegan Genotype Human Body

Appendix A-1: The Aboriginal Diet of Humans (Homo Sapiens)

ABSTRACT

A synthesis of multidisciplinary analyses documents listed in the Bibliography B. on the identity of the aboriginal
human diet clearly indicates that the aboriginal human diet was and by definition still is the Herbivore/Vegan Diet.
Thus it is no coincidence that the Herbivore/Vegan Diet is identified in the Bible Genesis 1: 29 as the “directive for
human nutrition” __ “food from the soil” and is part of the “Great Law” of General Human Systems Theory.

I. Ancient African, Eastern and Middle Eastern Cultures and Civilizations: “Golden Age”
[Vegan (No Animal Meat, Dairy Products or Meat) Diet]

Recent paleontology and archeological circumstantial evidence supports the premise that the Herbivore/Vegan Diet is
aboriginal is based on the new technique of hair analysis. SA Macko, et al in the article “The Ice Man’s diet as
reflected by the stable nitrogen and carbon isotopic composition of his hair” in FASEB Journal, V 13 (3), pp 559-
62, 1999 states that:

“We have also recognized a primary vegetarian component in the diet of the Neolithic Ice Man

of the Oetztaler Alps (5200 BP).“

Please note that in 5,000 BC. the “primary vegetarian component” was the herbivore/vegan diet.

The Herbivore/Vegan Diet of eating “foods from the soil” was aboriginally established by the African Culture in the
Nile River Valley theocracy of Ancient Egypt/Kemit lead by the priests of the esoteric “School of On (Annu or God)”
circa 100,000 BC. This dating is based on the genetic dating of the human genus homo sapiens female mitochondria
genome originating in Africa at circa 350,000 BC. The human mitochondria of hepatic (liver), vascular (blood vessel)
and kidney endothelial cells have the enzyme 27 Sterol Hydroxylase to detox Dietary Cholesterol metaphysically
designed from within a Vegan Diet genotype environment.

The Vegan Diet was and is characteristically founded upon the sustainable economic development technology of
Horticulture implemented by the esoteric “School of On (Annu or God)” based on integrated deep bed gardens and
forests using earthworm production and conservation of humus top soil without using animal husbandry to produce
its tree and plant sourced food stuffs.

The Vegan Diet was in ancient times and still is used by the Eastern Culture of the Ganges and Indus River Valley
Jain and Hindu civilizations of the Asian Sub-Continent of India and the Buddhist civilizations of China and South East
Asia which were in communication with the African Culture of the Nile River Valley theocracy of Ancient Egypt/Kemit
lead by the priests of the esoteric “School of On (Annu or God).”

The Vegan Diet was adopted by the ancient Ionian Greek Philosopher Pythagoras who was trained at the “School
of On (Annu or God)” of Ancient Egypt/Kemit. Pythagoras’ subsequent teachings influenced upper classes of the
ancient Greek and later Roman societies’ of the Mediterranean Sea.

“For as long as men massacre animals, they will kill each other. Indeed, he who sows
the seed of murder and pain cannot reap joy and love.”

Pythagoras (6th century BC)

The aboriginal Hippocratic Oath of ancient physicians is traceable to Pythagoras and the esoteric “School of On
(Annu or God).” It is notable the various modern Hippocratic Oaths taken by allopathic MD. physicians today are
significantly modified versions of the original oath.

The Vegan Diet was adopted by the ancient Hebrews, as their Patriarchs Joseph and Moses (alias esoterically
Pharaoh Akhenaton) were also trained at the “School of On (Annu or God)” of Ancient Egypt/Kemit. The Vegan Diet
was practiced by the Essene Hebrews who wrote the Dead Sea Scrolls. As proto-Christians the Essenes raised the
Nazarene Prophet John the Baptist who initiated the Christian Master Jesus Christ.

A. Quoting from the Encyclopedia Britannica on the Essene(s) {Hebrews/Jews}:

“According to Clement of Alexandria (200 A.D.) the Essenes were strict abstainers from flesh foods.”
“As a result of the ascetic training of the Essenes, and their temperate diet, it is said that they lived to a great
age, and were superior to pain and fear.”
“… they had in many respects reached the highest moral elevation attained by the ancient world, they were
just, humane, benevolent and spiritually-minded; the sick and the aged were the objects of a special
affectionate regard; they condemned slavery . . . as an impious violation of natural brotherhood of man.”
“Josephus says that the Essenes lived the same kind of life as did the Pythagoreans….. they entirely addict
themselves to husbandry... they are long lived also in so much that many of them live above a hundred years!”
PURPLE SEAL: BRCA, Inc. MEMBERS AND DESIGNATED NETWORK
THE PURPLE SEAL:: Breaking the Animal Dietary Cholesterol and DNA Related Diseases and Syndromes:
“The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA & Protein in the Aboriginal Vegan Genotype Human Body

Appendix A-1: The Aboriginal Diet of Humans (Homo Sapiens) _ page 2

B. “Dean Stanley points out certain evidence that St. John was an adherent of the Essenian philosophy....
Thus from the above St. John by inference was a vegetarian too.”
“The Homilies of Clement, according to Howard Williams”... assure us ‘that St. Matthew‘ lived upon seeds
and hard shell fruits and other vegetables, without touching flesh.”
“The Homilies of Clement, according to Howard Williams, represent St. Peter as a strict flesh-abstainer,
living upon bread and olives only, with the addition rarely of kitchen herbs. This information it is claimed was
given by St. Peter himself to Clement of Rome.”
“Eusebius states that St. James never ate any animal food.”
NOTE: St. James is St. James the Just, Jesus Christ’s brother and known Essene Nazarite.
“According to St. Augustine, he lived upon seeds and vegetables, never tasting flesh or wine.”

(from John Harvey Kellogg’s The Natural Diet of Man, 1923, pg. 77)

The Vegan Diet was adopted by the ancient Sebean civilization of Sheba in Asia Minor who also studied at the
“School of On (Annu or God)” of Ancient Egypt/Kemit. Their successors were the proto-Muslim Sufi Mystics who
initiated the founding Muslim Prophet Muhammad in the cave of Hira. Thus the Vegan Diet was introduced to the initial
Muslim societies of the Middle East.

Consequently, the Vegan Diet can be seen today reflected in the modern Mediterranean Diets of southern European
Mediterranean societies of southern France, Spain and Italy albeit using fish and wine instead of nuts, seeds and
unfermented grape and other fruit juices; and can also be seen today reflected in the modern Mediterranean Diets of
Muslim North African and Middle Eastern societies using for example Garbanzo bean based hummus, cous cous,
tabouli and goat dairy.

II. Ancient European and North Asian Culture and Civilizations : “Mammal Cannibalism”
[Omnivore/Mixed Diet]

The Western Culture of Europe and North Asia which invented Agriculture based upon domesticated grain and
legume “field plants” and based upon the animal husbandry of domesticated mostly mammalian animals was founded
by people who used the novel and experimental Omnivores Diet. This diet’s novel and experimental aspects stem from
the adaptation to the inclement weather of 90 to 120 day growing seasons in post Ice Age Europe and Northern Asia
spread around the world from the metaphysically militaristic cultures which used this aggressive behavior generating
Omnivores Diet. Dairy Products were fully established in Europe by 10,000 BC. and then taken to India by Rama
Krishna by 8,000 BC. in the Indo-European political and cultural merger.

In these temperate areas of Europe and Asia the mythical King Osiris and Queen Isis invented the new applied
science of agricultural around 10,000 BC. as opposed to the aboriginal applied science of horticulture. It was
needed to replace the heinous ritual and practice of cannibalism which was obviously socially despised and
ostracized and the often ineffective hunting of wild animals which was sporadic and caused their rapid
disappearance in Europe and Asia. This new applied science of agricultural had as its components
a.) domesticated animals mostly mammals; b.) animal husbandry; c.) animal manure based fertilizing; d.)
domesticated grains and legumes; e.) animal powered field plows; f.) farming of plots with ploughed parallel
fields and g.) Omnivorous diet which negated the perennial food shortage from the winter shortened growing seasons
in the temperate areas of Europe and Asia.

Note that the Omnivores Diet of these humans being mammals feeding from their own mammalian family group via
domesticated mammal animals initially constituted and still constitutes a form of “mammal cannibalism.” Sickness
treatment epistemologically this “pseudo” food generates in the human body autoimmune responses including
white blood cell’s production of antibodies and amyloid protein excretion and the liver’s detox conjugation with
glucose, the amino acid glycine and sulfonic acid taurine.

Unfortunately, this characteristically pastoral lifestyle using domesticated mostly mammalian animals sets into motion
the environmentally destructive interconnected vectors of pastoral overgrazing, the loss of humus top soil, the change
of local rain patterns from the progressive loss of shrub and trees breaking their provided ground water to atmospheric
water cycle and eventually the regional systemic death of trees resulting in large scale desertification and deforestation
wherever it is used.

The appearance of chronic diseases and syndromes herein called the Dietary Cholesterol and Related Diseases
and Syndromes (DCRDS) naturally manifests within any culture’s people soon after they adopt the novel and
experimental Omnivores Diet. This is because the human body can not properly utilize Dietary Cholesterol from
another mammal or human of which consumption results in immune system rejection as seen in Diabetes Mellitus,
fermentation and putrefaction microbial intestinal insanitation problems and/or initiation of serious prion infections.

The Great Britain Empire was based on the novel Omnivores Diet but its Royal Navy soon learned the bitter lessons
of the need for “foods from the soil” with scurvy, beriberi and pellagra caused vitamin deficiencies. During the Victorian
Age the tradition of fruit as the days first meal was replaced with “breakfast” or “break the fast of dinner” was instituted
avoiding fruits and vegetables and substituting with a heavy meat and carbohydrate morning meal.

Historically, the novel Omnivores Diet is still characteristically associated with 1.) environmental pollution with its over
grazing animal husbandry agriculture producing soil erosion and animal feces and urine runoff into surface water and
ground water tables; 2.) environmental destruction of desertification and deforestation ; 3.) unsustainable economics with
the ineffective use of grains and seeds to feed domesticated animals for food instead of feeding people; 4.) the chronic
diseases and syndromes better termed the Dietary Cholesterol and Related Diseases and Syndromes (DCRDS)
PURPLE SEAL: BRCA, Inc. MEMBERS AND DESIGNATED NETWORK
THE PURPLE SEAL:: Breaking the Animal Dietary Cholesterol and DNA Related Diseases and Syndromes:
“The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA & Protein in the Aboriginal Vegan Genotype Human Body

Appendix A-1: The Aboriginal Diet of Humans (Homo Sapiens) _ page 3

caused by the inevitable immune system rejection of its “pseudo food” elements and intestinal microbial toxemia; and 5.)
the continued militaristic endeavors and unhumanitarian “mean” culture this diet spawns/generates. Medieval Europe’s
constant wars, killing plagues originating from the chronic enteric anaerobic bacterial toxemic infections of all those
who eat animal meat and colonialization of militarily weaker people in the name of Jesus Christ were predictable
outgrowths of the experimental, novel and environmentally destructive and internally unsanitary Omnivores Diet.

Today the Omnivores Diet is still novel and experimental because the human genome will not accept it without exception.
This is seen in “industrialized countries” and in urbanized areas of “developing countries” where it is imported for example
by America’s MacDonald Restaurants; results in millions of people being malnourished, going hungry and being sickness
ridden from the chronic disease and syndromes based iatrogenic poverty and economic poverty generated by the
Omnivores Diet.

As recently reported by free lance journalist Andrea Stone 11/03/2009 on www.sphere.com America’s military recruiters
have declared that 75% of the American youth are unfit for military service because of overweight and obesity, mental
neurosis including drug and alcohol abuse and prison records. It is clear that the Omnivore Diet generating the chronic
diseases and syndromes including latest manifestation of Metabolic Syndrome is the cause of this Health National
Security crisis.

III. Origin of the Vegetarian Diets of Africa and Asia: “Accommodation”


[Lacto-Vegetarian (Dairy Products) Diet and Ovo-Lacto (Eggs and Dairy Products) Vegetarian Diet]

The Vegetarian Diet is related to the Vegan Diet but was developed later as a modification and socio-political
economic cultural accommodation of the invading peoples from Europe and North Asia who brought the Omnivores
Diet into Africa and Southern Asia who aboriginally used the Vegan Diet. By using the less cholesterol dense dairy
products of domesticated mammalian animals and eating little or no animal flesh “foods”, they attempted to ameliorate
Omnivores Diet’s deforestation and desertification vectors needing fewer Agricultural animal husbandry raised
domesticated mostly mammalian animals feeding themselves and their animals domesticated grains, legume and seed
producing plants.

Proof of this is that the domesticated mammalian animals the cow, goat, sheep and horse are not native to
Africa and were imported in by invader and migrant peoples.

This accommodation occurred in Ancient Egypt/Kemit with the defeat of the Pre-Dynastic invasion of the Dynastic
Race starting the 1 st Dynasty of the Dynastic Race esoterically mixed Caucasian and Asian Dravidian peoples. By
the 3 rd Dynasty diabetes mellitus was being described medically and being treated by the physicians of Ancient
Egypt/Kemit. The Omnivores Diet was later reintroduced during the Hyksos invasion and occupation from the
13 th to the 17 th Dynasties. This accommodation ended with the environmental and socio-political economic
destruction of this multi-millennium surviving civilization by successive invasions and occupations by the Omnivores
Diet based Persian, Greek and Roman civilizations.

The Greek City states were based mostly on the Omnivores Diet. However, take note that the vegan/vegetarian
teachings of Pythagoras had caused the upper classes in Athens to adopt the Vegetarian Diet as seen in the
personal dietary choice of the Philosopher Socrates.

The Roman Republic and later the Roman Empire was based on the Omnivores Diet. Yet take note that then
General Julius Caesar in his Memoirs relates that he had to change the diet of his army fighting against the
Vegetarian Diet using Gallic Tribes in his Gallic Wars as the Gallic women were killing his troops in hand to hand
combat.

This accommodation occurred in Ancient India with the invasion of the Europeans lead by Rama and subsequent
invasions of the Omnivores Diet Scythians. The later invasion attempt by the Omnivores Diet using Macedonian
Greek lead by Alexander the Great ended in his mortal wounding. Likewise the later attempt by the Omnivores
Diet using Roman Empire invasion of India was repulsed with the Roman Emperor himself killed in battle largely
from the hand to hand combat superiority of the Vegetarian Diet using Indian army.

The later successful invasion and occupation by the Omnivores Diet based Great Britain Empire of India ended with
the environmental and the socio-political economic destruction of mega-India now split into the nations of Pakistan,
Bangladesh and India. All these nations are struggling with various forms of socio-political economic problems
stemming from the Vegetarian Diet and requisite Agricultural technology base.

The ultimate defeat of the Nazi Germany World War II military was due to the comparative inferiority of its food stuffs
forced by the British and American Naval blockade from getting the importation of phosphate, phosphorus, animal
manure and other natural organic fertilizers. The Nazi’s turned to the novel and experimental “organic chemistry” to
use for the first time on a large scale N-P-K chemical fertilizers derived oil petroleum to produce its domesticated
animals and vegetable, grain and food products.

The differences of animal husbandry practices of the western civilization and the eastern civilization in the raising of
cattle and the production of dairy products is reflected in the former’s use of these animals as animal meat sources and
the latter’s forbidding such use as violating a sacred animal. Thus the western civilization animal husbandry practice
has dairy products with high levels of cholesterol derived from using the cows milk sac lining or rennet in dairy products
and the eastern civilization animal husbandry practices having dairy products practically devoid of cholesterol.
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Appendix A-1: The Aboriginal Diet of Humans (Homo Sapiens) _ page 4

T. Colin Campbell, Ph.D., of Cornell University, director of a study of 6,500 Chinese found a close correlation
between meat consumption and the incidence of heart disease and cancer.

"Usually, the first thing a country does in the course of economic development is to introduce a lot of livestock.
Our data are showing that this is not a very smart move and the Chinese are listening. They are realizing that
animal-based agriculture is not the way to go.... We are basically a vegetarian species and should be eating a
wide variety of plant food and minimizing our intake of animal foods.... Once people start introducing animal
products into their diet, that's when the mischief starts."

IV. Mitochondrial Eve, the Evolution of Homo Sapien and Great Law of Vegan Human Diet

Front Cover of the January 11, 1988 Newsweek


presenting the Mitochondrial Eve Hypothesis
Sold a record number of copies [Wikipedia]

The Human Genetics article by RL Cann, et al “Mitochondrial DNA and human evolution”, Nature, V. 325 No. 6099,
pp 31- 6, 1987 was reported in Newsweek in January 11, 1988 under the title article “The Search for Adam and Eve:
Scientists Explore a Controversial Theory About Man’s Origin.” Commonly known as the Mitochondrial Eve
Hypothesis it was initially intensely resisted by the world of science but has been accepted because of the scientific truth
that DNA analysis has brought to the world. It is based on the distinct uniqueness of the cellular organelle of the
mitochondria which is the major energy producing element in the human body from food that is eaten; i.e. the
mitochondria has its own DNA in addition to that of the cellular nucleus DNA and that mitochondrial DNA
(mtDNA) is passed down from human mothers to their sons and daughters.

Consequently, it has been determined by Human Genetics that there existed a woman Mitochondrial Eve from whom
all living humans are descended who lived most likely in East Africa next to the Central African Great Lakes in circa
200,000 B.C. Thus the evolution of humanity began in the Quaternary/Pleistocene Period 2.5 million years ago to the
present age from a single, continuous human species Homo sapiens evolving worldwide to the modern Homo sapien
sapiens. Please refer to Appendice A-3 on the detail of the hominid struggle between competing archaic humans of
various dietary practices including Vegan Diet, Omnivore Diet and Carnivore Diet which produced the Quaternary
Ice Age still on going. In turn the Out of Africa Hypothesis for the origin of all living humans known as Homo Sapien
Sapien states that all the human races originated in Africa circa 200,000 BC and that about 60,000 BC. they migrated out
of Africa to populate Europe and Asia and the Western hemisphere of North and South America.

The Mitochondrial Eve Hypothesis with her living circa 200,000 and the Out of Africa Hypothesis of homo sapiens
sapiens appearing in 200,000 BC in East Africa and migrating world wide circa 60,000 BC. are totally in line with the
Ancient Egyptian/Kemitian “School of On (Annu or God)” documentation of the founding of Ancient Egypt/Kemit by
“human gods” the Anu Peoples who followed the Vegan Diet, built the engineering marvels of the Great Pyramids and
Sphinx Rock Sculpture Complex at Giza and practiced mediation on the cosmic light and sound of the “Big Bang” source
the Most High God Annu. Full detail of the “School of On” is presented on http://www.theuniversityofgod.org/.

This is why all other archaic Homo species see Appendice A-3 Table I competing with Homo sapiens
became extinct because of their breaking the Great Law of Vegan Human Diet as Homo sapiens were the
offspring of the Vegan Diet eating Hominids Australopitheus and Paranthropus. Although their brains were small
their cerebral frontal lobes were adequate to be smart enough to walk on 2 feet and follow the Vegan Diet.

The Rastafarian Priests and Priestesses of the Ancient Egyptian/Kemitian “School of On (Annu or God)” were the
source of the Bible Genesis 1: 29 declaration of the Great Law of Vegan Human Diet as Moses who wrote Genesis
had been trained at the “School of On.”

Consequently, It is not a coincidence that cellular mitochondria:

a.) are the foundation of the Mitochondria Hypothesis;

b.) biochemically reject animal derivative fat, protein and carbohydrates as energy sources;
and

c.) begin in the lungs and arteries the Bile Acid detoxification of Oxycholesterol 27 the Dietary
Cholesterol rotting waste residue from ingesting meat in the fetus, child, youth and adult
human body as it is Vegan Genotype Genome endowed and this can not be changed.
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Appendix A-2: Aboriginal Christians Were Vegans

This document is based on one originally entitled “Are Christians Vegetarians?” by Keith Akers of the
Denver, Colorado, Vegetarian Society and a former North American Regional Secretary for IVU.
He wrote it in association with Richard Shorter of London, England. It has been modified herein by
George W. Singleton, 2007 and 2009 European Union Humanitarian Grantee in support of the
Green Paper:: Appendix A-1: The Aboriginal Diet of Humans. Most Christians today probably eat
animal meat without giving it a second thought. But many early Christians were vegan not even dairy
product partaking vegetarians including Clement of Alexandria, Origen, John Chrysostom, and Basil
the Great.

I. Writings on the Jesus Christ Disciples as Vegans

According to some early church writings the Apostles Matthew, Peter and James (the brother of
Jesus and first leader of the Jerusalem church) were vegans.

a.) “It is far better to be happy than to have your bodies act as graveyards for animals. The
Apostle Matthew partook of seeds and nuts and vegetables without flesh.”

Clement of Alexandria, The Instructor, book 2, chapter 1

Note: Clement of Alexander was the second leader of the Catechetical School of Alexander, Egypt [later
named in the Roman Catholic Church the Bishop of the aboriginal Christian Gnostic Church]
created by the Disciples of Jesus Christ’s fully 200 years before it was co-opted by the omnivore
Emperor Constantine of omnivore Roman Empire. Quite naturally for “empire security” and animal meat
industry reasons the vegan and gardening lifestyle of Jesus Christ a Hebrew Essene was changed
to meat eating fisherman.

b.) “Apostle Peter said, "I live on olives and bread to which I rarely only add vegetables."

Pseudo-Clementine Homolies 12, 6; also Recognitions 7,6.

c.) “Apostle James (the Just), the brother of the Lord ... was holy from his mothers womb;
and he drank no wine nor strong drink, nor did he eat flesh.”

Hegesippus, quoted in The Church History of Eusebius, book 2, chapter 23.

II. Early Christian Clergy and Saints Testimony

a.) “Sacrifices were invented by men to be a pretext for eating flesh.”

Clement of Alexandria (150 – 215 AD)

Note: Please note that it is not a coincidence that:

1.) Clement of Alexander the Bishop of the aboriginal Christian (Gnostic) Church
was a vegan and his student Origen (c. 185-254 AD) who became the next Bishop
of Alexandria and First Theologian of the Christian Church too was vegan;

2.) Clement of Alexander was the last to have seen and given a detailed description
of the now missing 42 Books of Thoth;

3.) these text books of the Ancient Egypt/Kemit “School of On (God or Annu) were
based on the Great Law of humans as herbivores and the vegan diet;

4.) the “School of On” trained Hebrew Patriarchs Joseph and Moses (esoterically
Ancient Egyptian Pharaoh Akhenaton), and Moses writing about the creation of
earth dictates clearly the Bible Genesis 1: 29 vegan human diet directive; and

5.) the “School of On” trained Greek Philosopher Pythagoras (c 570- 495 BC) who
introduced the vegan lifestyle to the Greek civilizations surviving as the
Mediterranean Diet.
2.
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Appendix A-2: Aboriginal Christians Were Vegans

b.) “The eating of meat was unknown up to the big flood, but since the flood they
have the strings and stinking juices of animal meat into our mouths, just as
they threw in front of the grumbling sensual people in the desert.”
“Jesus Christ, who appeared when the time had been fulfilled, has again joined
the end with the beginning, so that it is no longer allowed for us to eat animal meat.”

St Jerome (347- 420 AD)

c.) “The steam of meat meals darkens the spirit. One can hardly have virtue if one
enjoys meat meals and feasts. In the earthly paradise there was no wine, no one
sacrificed animals, and no one ate meat.”

St Basil (330 – 379 AD)

d.) “Not to hurt our humble brethren is our first duty to them, but to stop there is not enough.
All things of creation are children of the Father and thus brothers of man ...”
“God wants us to help animals, if they need help. Every creature in distress has the
same right to be protected.”
“If you have men who will exclude any of god's creatures from the shelter of compassion
and pity, you will have men who will deal likewise with their fellow men.”

St Francis of Assisi (1181- 1226 AD)

e.) “If man wants freedom why keep birds and animals in cages? Truly man is the king of beasts,
for his brutality exceeds them. We live by the death of others. We are burial places! I have
from an early age abjured the use of meat, and the time will come when men such as I look
upon the murder of animals as they now look upon the murder of men.”

Leonardo da Vinci (1452-1519 AD)

Note: This would explain his monumental masterpiece the Last Supper with Jesus Christ,
his Disciples including Mary Magdalene painted seated at a table set as a vegan
dinner with no animal meat in sight.

III. Bible References: Vegananism: Original Ideal and Ultimate Hope

a.) And God said, "Behold, I have given you every plant yielding seed which is upon the face
of all the earth, and every tree with seed in its fruit; you shall have them for food. And to
every beast of the earth, and to everything that creeps on the earth, everything that has
the breath of life, I have given every green plant for food."

Bible Genesis 1:29-30

b.) The wolf shall dwell with the lamb,


and the leopard shall lie down with the kid,
and the calf and the lion and the fatling together,
and a little child shall lead them.
The cow and the bear shall feed;
their young shall lie down together;
and the lion shall eat straw like the ox.
The suckling child shall play over the hole of the asp,
and the weaned child shall put his hand on the adders den.
They shall not hurt or destroy in all my holy mountain;
for the earth shall be full of the knowledge of the Lord
as the waters cover the sea.

Bible Isaiah 11:6-9


3.
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Appendix A-2: Aboriginal Christians Were Vegans

c.) Then I will make a covenant on behalf of Israel with the wild beasts, the birds of the air,
and the things that creep on the earth, and I will break bow and sword and weapon of
war and sweep them off the earth so that all living creatures may lie down without fear.

Bible Hosea 2:18

d.) He shall wipe away every tear from their eyes, and death shall be no more, neither shall
there be mourning nor crying nor pain any more, for the former things have passed away.

Bible Revelations 21:4

e.) I said in mine heart concerning the estate of the sons of men, that God might manifest them,
and that they might see that they themselves are beasts. For that which befalleth the sons of
men befalleth beasts; even one thing befalleth them: as the one dieth, so dieth the other; yea
they have one breath; so that a man hath no preeminence above a beast for all is vanity. Yea.

Bible Ecclesiastes

f.) Children in whom was no blemish, but well-favored, and skillful in all wisdom, and cunning in
knowledge, and understanding science...and the King appointed them a daily provision of the
King’s meat, and of the wine which he drank... But Daniel proposed in his heart that he would
not defile himself with the portion of the King’s meat, nor with the wine which he drank…
Therefore he requested that he might not defile himself. Prove thy servants, I beseech thee,
ten days; and let them give us pulse (vegetable legumes) to eat, and water to drink. Then let
our countenances be looked upon before thee, and the Countenance of the children that eat
of the portion of the King’s meat: And as thou seest, deal with thy servants. And at the end of
ten days their countenance appeared fairer and fatter in flesh than all the children which did
eat the portion of the King’s meat. Thus Meizar took away the portion of their meat, and the wine
that they should drink; and give them pulse. As for these Children, God gave them knowledge
and skill in all learning and wisdom: and had understanding in all visions and dreams.

Bible Daniel 1:4-17 (excerpts thereof)

IV. Bible References: God Cares About Animals and Wants Us To Care About Animals

a.) The Lord is good to all men, and his tender care rests upon all his creatures.

Bible Psalms 145:9

b.) Look at the birds of the air; they do not sow and reap and store in barns,
yet your heavenly Father feeds them.

Bible Matthew 6:26

c.) A righteous man cares for his beast.

Bible Proverbs 12:10

d.) When you see the ass of someone who hates you lying helpless under its load,
however unwilling you may be to help it, you must give him a hand with it.

Bible Exodus 23:5

e.) When you see your fellow countryman’s ass or ox lying on the road, do not ignore it;
you must help him to lift it to its feet again.

Bible Deuteronomy 22:4


4.
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Appendix A-2: Aboriginal Christians Were Vegans

f.) He who slaughters an ox is like him who kills a man.

Bible Isaiah 66:3

V. Bible References: Animal Sacrifices Are Rejected by God

a.) Your countless sacrifices, what are they to me? says the Lord. I am sated with
whole-offerings of rams and the fat of buffaloes; I have no desire for the blood of
bulls, of sheep and of he-goats. Whenever you come into my presence - who asked
you for this? No more shall you trample my courts. The offer of your gifts is useless,
the reek of sacrifice is abhorrent to me.

Bible Isaiah 1:11-12

b.) There is blood on your hands; wash yourselves and be clean.

Bible Isaiah 1:16

c.) For a desire steadfast love and not sacrifice, the knowledge of God, rather than
burnt offerings.

Bible Hosea 6:6

d.) Because Ephraim has made many alters for sin, they have become for him alters for sinning.
I have written for him the great things of my law (Genesis 1:29) but they were considered a
strange thing for the sacrifices of my offerings. They sacrifice flesh and eat it. But the lord
does not accept them. Now He will remember their iniquity and punish their sins.

Bible Hosea 8:11-13

e.) If you had known what that text means, "I require mercy, not sacrifice", you would not have
condemned the innocent.

Bible Matthew 12:7

VII. Past and Present Notable Philosophers, Scientists and Authors Testimony

a.) “But for the sake of some little mouthful of flesh we deprive a soul of the sun and light, and of
that proportion of life and time it had been born into the world to enjoy.”

Plutarch (c. 46- c.120 AD)

b.) "The animals you eat are not those who devour others; you do not eat the carnivorous beasts
you, take them as your pattern. You only hunger after sweet and gentle creatures who harm
no one, which follow you, serve you, and are devoured by you as the reward of their service."

John-Jacques Rousseau (1712-1778 AD)

c.) “Flesh eating is unprovoked murder.”

Benjamin Franklin (1706-1790 AD)

d.) “I have no doubt that it is part of the destiny of the human race in its gradual improvement
to leave off eating animals.”

Henry David Thoreau (1817-1862 AD)


5.
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e.) “Nothing more strongly arouses our disgust than cannibalism, yet we make the same
impression on Buddhists and vegetarians, for we feed on babies, though not our own.”

Robert Louis Stevenson (1850-1894 AD)

f.) “Let no one regard as light the burden of his responsibility. While so much ill-treatment
of animals goes on, while the moans of thirsty animals in railway trucks sound unheard,
while so much brutality prevails in our slaughterhouses ... we all bear guilt. Everything
that lives has value as a living thing, as one of the manifestations of the mystery that is life.”

“Until he extends the circle of compassion to all living things, man will not himself find peace.”

Albert Schweitzer (1875-1965 AD)

g.) “A man can live and be healthy without killing animals for food; therefore, if he eats meat, he
participates in taking animal life merely for the sake of his appetite. And to act so is immoral.”

“Flesh eating is simply immoral, as it involves the performance of an act, which is contrary
to moral feeling: killing. By killing, man suppresses in himself, unnecessarily, the highest
spiritual capacity, that of sympathy and pity towards living creatures like himself and by
violating his own feelings becomes cruel.”

Leo Tolstoy (1828- 1910 AD)

f.) “My situation is a solemn one. Life is offered to me on condition of eating beefsteaks.
But death is better than cannibalism. My will contains directions for my funeral, which
will be followed not by mourning coaches, but by oxen, sheep, flocks of poultry, and a
small traveling aquarium of live fish, all wearing white scarfs in honor of the man who
perished rather than eat his fellow creatures.”

George Bernard Shaw (1850 -1956 AD)

g.) ”Nothing will benefit human health and increase chances for survival of life on earth as
much as the evolution to a vegetarian diet.”

Albert Einstein (1879-1955 AD)

h.) “In every respect, vegans appear to enjoy equal or better health in comparison to both
vegetarians and non-vegetarians.”

T. Colin Campbell, PhD Professor of Nutrition, Cornell University (letter dated 3/29/98)

i.) "There will come a time...when civilized people will look back in horror on our generation and the
ones that preceded it: the idea that we should eat other living things running around on four legs,
that we should raise them just for the purpose of killing them! The people of the future will say
‘meat-eaters!’ in disgust and regard us in the same way we regard cannibals and cannibalism."

Dennis Weaver

j.) “Your choice of diet can influence your long term health prospects more than any other action you
might take.

Former Surgeon General C. Everett Koop

k.) "The beef industry has contributed to more American deaths than all the wars of this century, all
natural disasters, and all automobile accidents combined. If beef is your idea of `real food for real
people,' you'd better live real close to a real good hospital."

Neal D. Barnard, M.D.,


President, Physicians Committee for Responsible Medicine, Washington, D.C.
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l.) "All red meat contains saturated fat. There is no such thing as truly lean meat. Trimming away the
edge ring of fat around a steak really does not lower the fat content significantly. People who have
red meat (trimmed or untrimmed) as a regular feature of their diets suffer in far greater numbers
from heart attacks and strokes."

Michael Klaper, M.D.,


Medical Director, Earth Save Foundation, Santa Cruz, California

m.) "If you step back and look at the data, the optimum amount of red meat you eat should be zero."

Walter Willett, M.D., Professor at Harvard School of Public Health (Departments of


Epidemiology and Nutrition), wrote editorial “Diet and Cancer” in the January 12, 2005,
Journal of American Medical Association (JAMA), V. 293, pp 234-4 in support of the
American Cancer Society study [Chao, Ann, et al, “Meat Consumption and Risk of
Colorectal Cancer,” JAMA, V. 293, pp 172-182] that found a close correlation between
red meat consumption and colon cancer.

n.) "Usually, the first thing a country does in the course of economic development is to introduce a lot
of livestock. Our data are showing that this is not a very smart move and the Chinese are
listening. They are realizing that animal-based agriculture is not the way to go.... We are basically
a vegetarian species and should be eating a wide variety of plant food and minimizing our intake
of animal foods.... "Once people start introducing animal products into their diet, that's when the
mischief starts."

T. Colin Campbell, Ph.D., of Cornell University, director of a study of 6,500 Chinese that
found a close correlation between meat consumption and the incidence of heart disease
and cancer. [Campbell, T. Colin; Campbell II, Thomas M.; Lyman, Howard, The China Study:
The Most Comprehensive Study of Nutrition Ever Conducted and the Startling Implications
for Diet, Weight Loss and Long-Term Health, 2006]
APPENDIXE A-3. The Ramifications of the Invention of Hunting, Animal Husbandry
Agriculture and Novel & Experimental Carnivore and Omnivore Diets

A. Preface : The origin of Animal Meat Eating Spawns The White Race and
The Myth of White Supremacy

B. Introduction: The Aboriginal Human Condition of Diet, Habitat and


Occupation

C. Deleterious Ramifications

I.) Decrease in Atmospheric CO2 and Beginning of Present


Quaternary Ice Age [circa 3,000,000 BC to present]

Table I. Inventory Table of Ancient Hominids: Plant Food


Gatherers, Dead Animal Meat Scavengers and
Alive Animal Hunters

Table II. Inventory Table of Anthropogenic Extinct European


and Asian Mega-Fauna

A. World Off Axis

B. World Flips Upside Down

II.) Loss of Humus Top Soil Desertification and Deforestation

III.) Loss of Black Skin Color to Brown and Yellow Color By Those
European and Asian Peoples Following the Novel Omnivore Diet

IV.) Loss of Brown Skin Color to White Skin Color by those following
the Demonic Carnivore Diet

A. Neanderthal Mutation of Pale White Skin [circa 200,000 BC.]

B. European Homo Sapiens Sapiens Mutation From Brown to


White Skin [circa 18,000 BC]
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Appendix A-3: The Ramifications of the Inventions of Hunting, Animal


Husbandry Agriculture and the Novel and Experimental
Carnivore and Omnivore Diets

PREFACE: THE ORIGIN OF ANIMAL MEAT EATING SPAWNS THE WHITE RACE
AND THE MYTH OF WHITE SUPREMACY

The twin poles of the Devil ___ Lucifer (ego or “I am better than everyone and everything is for me”
and Ahriman (id or “I want to be wicked and do everything that is demonically abnormal”)] and
their Sorcery Priest and Priestess lead followers made the demonic eating of animal meat ritual
appear as “normal.” They obviously recognized the deleterious ramifications to “normalcy” that subsequently
manifested on the Earth and its inhabitants as they are in a permanent state of denial. To this day they do not
want it revealed that what seems “natural” their invention of hunting, their invention of domesticated animal
based agriculture and their invention of the Carnivore Diet and adoption of the novel Omnivore Diet is what
started the present on-going 3,000,000 (M) year old Quaternary Ice Age. Its huge glaciers still dominate the
planet and the planet is in an unnatural upside down and off axis orbital status requiring leap year every 4
years to resolve the annual solar calendar error.

The Devil has the entire planet in a “scarcity chaos” illusion with 3% of the people controlling 95% of
conventional economic productive resources while 45% of the world’s people live on $3 or less a day. After
3,000,000 years glaciers still today dominate Earth and global warming is looming threatening to flood the
international coastlines with a rise of the sea. With the Earth’s land being 4/5 ice and sand deserts the human
right of sustainable economic development opportunities are not accessible to the majority of Earth’s
people living in poverty or living in marginal “middle class” economic survival stasis a few paychecks removed
from poverty.

The majority of the Earth’s people live just 3/5 their possible life spans being victimized by a chronic disease
and syndrome plague from the ignorant daily eating of the “slow poison” of animal meat and rennet
containing dairy products. Shamelessly, the health care industry makes tremendous money from treating the
resulting preventable largely autoimmune Dietary Cholesterol and Related Diseases and Syndromes in 2010
$2.5 trillion dollars for health care expenses were spent in America alone largely on symptom manipulating
pharmaceutical drugs. Iatrogenic poverty looms above rich and poor like a vulture.

Esoterically, the Devil wants humankind addicted to ingesting animal flesh and organ residues including
rennet dairy products because it calcifies and makes dysfunctional the "third eye" or pineal
endocrine gland embedded in the middle of the brain of any given human who a priori possesses a vegan
human genetic genome producing the following deleterious human biological ramifications:

1.) Their brain can not properly access their spirit which is the only part of the human entity
that can differentiate "right from wrong;" "truth from non-truth" and "real from the
unreal" preferences and choices of temptation the Devil and its agents have concocted
in the name of civilization; and

2.) Reduces the body’s melanogenesis production of the black and brown skin color
pigment melanin not only lightening the skin color but increasing the chance of skin
cancer from sunlight UV radiation.

Esoterically, it must be noted that the Pineal endocrine gland’s main produced hormone is melatonin
derived from the amino acid tryptophan. Melatonin in turn activates the also embedded within the brain
Pituitary endocrine gland whose anterior lobe produces the hormone Melanocyte Stimulating Hormone
(MSH). MSH as its name infers stimulates the human body’s melanocytes to produce the skin color pigment and
light energy storing melanin.

Consequently, the white colored ice and snow was a portent of the Quaternary Ice Age’s cold temperate
weather and inverse solar radiation from the Equator bearing witness to the bizarre phenomena of a series
of genetic mutations generating white human skin color ultimately creating the European White Race
from the experimental, novel and abnormal for human consumption Carnivore Diet motivated by the illogical
mythology of White Supremacy that insanely fueled the hunt killing of Europe’s Megafauna to extinction
and yielding the colonization of the entire world’s humanity at its height in the mid-Twentieth Century leading to
World War II and now the colonial free 190 nations of the United Nations.

Thus as a consequence of the 3 M year Quaternary Ice Age ironically its causation is as “big as day” but
metaphysically the modern humans and their technologically advanced sciences and social religions can not
discern it as being the breakage of the Great Law of Vegan Human Diet.
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Appendix A-3: The Ramifications of the Invention of Hunting, Animal Husbandry


Agriculture and the Novel and Experimental Carnivore and
Omnivore Diets _ page 2

INTRODUCTION: THE ABORIGINAL HUMAN CONDITION OF DIET, HABITAT AND


OCCUPATION

Consequently, the General Human Systems Theory (GHST) Paradigm’s Analysis and
Synthesis Mode has been applied to the multidisciplinary documents listed in the Bibliography B.
Religious, Spirituality and General Human Systems Theory Texts and the results represented in
Flow Chart #1. General Human Systems Theory (GHST) Poverty Systems Analysis--Detailed established that:

A.) the aboriginal human diet is the Vegan/Herbivore Diet as reflected in the Great Law of the
Vegan Human Diet expressed in the Bible Genesis 1: 29 “directive for human nutrition;” and

B.) the aboriginal human habitat being the legendary Garden(s) of Eden in Ancient Egypt/Kemit
with the aboriginal human occupation of Sustainable Horticulture Forestry growing “organic
food from the soil” dominates the Bible Genesis.

In contrast the General Human Systems Theory predicts the existence of serious ramifications from the
Western Civilization Caucasian Peoples and the Eastern Civilization Asian Peoples breaking the Great
Law of the Vegan Human Diet by their fabricating the following novel and experimental biological
inventions of:
1.) Hunting and eating wild animals where as A priori hunting by Hominids is an invention
because without the conceptualization and fabrication of tools of hunting made out of
stone, leather and wood Hominids are not naturally equipped for hunting, killing, cooking
and eating other animals and other Hominids;

2.) Animal Husbandry Agriculture utilizing the inventions of a.) domesticated animals, b.) dairy
products and c.) cereal grains;

3.) Carnivore Diet an initial invention of the European Hominids as evidenced the
Neanderthals (Homo erectus) who suffered a white skin color MC1R genetic mutation
and European Homo sapien who suffered a white skin color SLC24A5 mutation;

4.) Omnivorous Diet an initial invention of the Asian Peoples and later adopted by the
European Peoples; and

5.) Chemical Medicines to ameliorate the symptoms from the proliferating chronic diseases and
syndromes caused by the eating of animal flesh and dairy product “Pseudo” food as animal/dietary
cholesterol and animal DNA, protein and fats are mutagenic, carcinogenic, atherogenic,
cholestogenic and cytotoxic.

DELETERIOUS RAMIFICATIONS

The GHST identified ramifications have been devastating for the Inventors, for the planetary animals, the
Earth environment and for all the other planetary Peoples beginning in 3,000,000 BC. for the Quaternary
Ice Age are as follows:

I.) Atmospheric carbon dioxide (CO2) decreases and the lowered temperature
world wide leads to catastrophic glaciation wherein the earth adjusts by:

A.) Rotating off axis up to 24 degrees initiating 4 seasons, continual


global glaciations and water, wind and snow and ice storms; and

B.) world flips over 3 times and presently upside down with global
flooding each time;

II.) Loss of humus top soil to the ocean and lake floors and desertification and deforestation;

III.) Loss of black skin color to brown and yellow skin color by those European and Asian
Peoples following the novel Omnivore Diet;

IV.) Loss of brown skin color to white skin color by users of the demonic Carnivore Diet
THE PURPLE SEAL:: Breaking the Animal Dietary Cholesterol and DNA Related Diseases and Syndromes:
“The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA & Protein in the Aboriginal Vegan Genotype Human Body

Appendix A-3: The Ramifications of the Invention of Hunting, Animal Husbandry


Agriculture and the Novel and Experimental Carnivore and
Omnivore Diets _ page 3

V.) Starting of the human chronic diseases and syndromes and the lowering of human life
expectancy from 130 years to 80 years characterized by autoimmune diseases and
dietary cholesterol and animal flesh related diseases and syndromes including Vitamin D
deficiency and subclinical malnutrition from over processed foods and “pseudo” foods;

VI.) Starting of the infectious diseases and syndromes from pathogenic viruses, bacteria,
fungus, mold, protozoa and insects feeding on unsanitary blood and body condition,
Not unsanitary urban environment and environmental health imbalances;
Addressed
In VII.) Female menstruation ensues from eating animal flesh foods; demonic instituted female
This clitoral surgical removal and male penis foreskin circumcision; and sex hormone
Appendix deficiency from Dietary Cholesterol ingestion has created a dysfunctional human
A-3 sexuality dominated by a clandestine bi-sexuality, male infidelity and fornication and
female “rape by consent” (coitus intercourse devoid of female orgasm);

VIII.) Initiating violent sexual rape and other violent crimes from subclinical malnutrition and
Iatrogenic poverty; and “white collar” non-violent crimes; and

IX.) Initiating historically European and Asian colonializing invasions world wide; and modern
civil, terrorist and national wars in national societies where 3% of the population controls
98% of the means of production leaving 45% of the population living on $3 or less a day.

I.) DECREASE IN ATMOSPHERIC CO2 AND BEGINNING OF PRESENT ICE AGE

Quaternary Glaciation in Northern Hemisphere showing


Glaciers in light blue [Wikipedia]

The biggest mystery that modern science has is what caused the present Quaternary Ice Age of
a continual glacial period that started 3 Million years ago? No one has causally figured it out. The
symptomatic question everyone is confused by is why was there a 10 fold decrease in the amount
of carbon dioxide (CO2) the green house gas that keeps heat on the planet like a blanket just
before and during this 3 M year ice age? This 10 fold decrease has been documented in the
Greenland Glacial ice core studies.

As well known CO2 or carbon dioxide is the “greenhouse gas” made primarily by the respiration of
the planet’s oxygen breathing fauna animals while symbiotically the planetary flora of ocean
plankton and sea weeds, aquatic algae and land plants and trees turn CO2 into oxygen via
photosynthesis making food from sunlight and water: 6 CO2 + 12 H2O ĺ C6H12O6 + 6 O2 + 6 H2O
THE PURPLE SEAL:: Breaking the Animal Dietary Cholesterol and DNA Related Diseases and Syndromes:
“The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA & Protein in the Aboriginal Vegan Genotype Human Body

Appendix A-3: The Ramifications of the Invention of Hunting, Animal Husbandry


Agriculture and the Novel and Experimental Carnivore and
Omnivore Diets _ page 4

The present Quaternary Glacial Period has not stopped as evidenced by the glacier at Antarctica
not ceasing for 3 Million years. We are in an interglacial period that began at circa 15,000 BC. The
previous Karoo Glacial Period was 300 Million years ago and the weather between those
glaciation periods was calm and temperately perfect.

Antarctica Glaciation, Southern Hemisphere [Wikipedia]

In circa 3,000,000 BC the ancient Earth’s peoples who were of the species homo but not sapiens but
their ancestors first invented hunting to satisfy a demonic whim to make things easier instead of
foraging the “Gardens of Eden” forests for fruits, seed, nuts, tubers and herbs. The devil took some
of them over and they began systematically killing the wild animals we are talking about in mostly
Europe and Asia this began. So by killing so many animals for food and dismissing being vegans
this is what started the decrease in carbon dioxide.

Conventional anthropology teaches us that hunting is “natural” but it is not it had to be invented
because the ancient humans were vegans/herbivore in genome and behavior until the “devil of
invention” unleashed another way to live humans as unnatural carnivore hunters. The invention of
hunting tools is interpreted by anthropology as progress instead of its metaphysical reality as a
developmental degeneration as seen by its consequences the 3 M year old Quaternary Glacial
Period. This would help explain why many homo subspecies H. erectus (Africa, Eurasia); H.
antecessor (Spain), H. cepranensis (Italy); H. georgicus (Georgia); H. neanderthalensis (Europe,
Western Asia) disappeared because of their failure to discern and follow the Great Law of the
Vegan Human Diet.

The Purple Seal calls this "mammal cannibalism" as most of the wild animals were mammals.
When the concentration of CO2 went down in the atmosphere and the earth got colder the
glaciation started with the earth going upside down and rotating off axis up to 24 degrees so it is
dark at the north pole in the Northern Hemisphere winter and dark at the south pole in the
Northern Hemisphere summer. Glaciers formed that were several miles thick.

Consequently what appears as just a simple mistake of breaking the Great Law of the Vegan
Human Diet causes such a gigantic disaster. This made hunting even more necessary as the
Garden of Eden was partly destroyed by the glaciers and the Northern and Southern Hemisphere
growing seasons shortened to as little as 90 days.

Esoterically, the following I. Inventory Table of Ancient Hominids: Plant Food Gatherers,
Dead Animal Meat Carrion Scavengers and Alive Animal Hunters documents the
evolutionary struggle between the Vegan Diet hominids Australopithecus and Paranthropus with the
Carnivore Diet and Omnivore Diet hominids Homo leading to in 200,000 BCE the Homo Sapien
Sapien from their interracial mixing.

The II. Inventory Table of Anthropogenic Extinct European and Asian Mega-Fauna records
the incredible “mega-fauna” animal extinctions at the hands of the hunting inventing Homo hominids
leading to the significant reduction in atmospheric CO2 and the onset of the Quaternary Ice Age.
THE PURPLE SEAL:: Breaking the Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in the
Aboriginal Vegan Genotype Human Body

Appendix A-3: The Ramifications of the Inventions of Hunting, Animal


Husbandry Agriculture and the Novel and Experimental
Carnivore and Omnivore Diets _ page 5-1

I. Inventory Table of Ancient Hominids: Plant Food Gatherers, Dead Animal


Meat Carrion Scavengers and Alive Animal Hunters

Hominid Dates Area Statue Weight Cranial Fossil Stone Tools Year
Species (x 106 BC (feet) (lbs.) Size Record Found Discovered
M years ) (cm3)

1. Australopithecus 3.8 -- Tanzania Many no 1974/2000


(A.) afarensis 3.0 Ethiopia Gatherer

2. A. 2.8- South Many yes 1924/1947


africanus 2.5 Africa Gatherer

3. Paranthropus 2.5 Kenya no 1985


(P.) aethiopicus Gatherer

4. Homo (H.)
Gauten- 2.5 – South 3.3 ft 110 1 skull Gatherer, 1977/2010
gensis 0.6 Africa lbs. yes-[O]

5. H. 2.3 - Tanzania, 3.3 - 73-120 510- Many Scavenger, 1960/64


habilis 1.4 Kenya 4.9 ft lbs. 660 Gatherer
yes-[O]
6. P. 2.0 South 1938
robustus Africa

7. H.
rudolfensis 1.9 Kenya 1 skull Gatherer 1972/86
no

8. H. 1.9- Eastern & 6.2 ft 700- Many Hunter 1975


ergaster 1.4 Southern 850 yes- [O] [A]
Africa

9. H.
georgicus 1.8 Georgia 600 4 Hunter 1999/02
individuals yes- [O]

10. H. 1.5- Africa 850 - Many Hunter 1891/92


erectus 0.2 Eurasia* 5.9 ft 130 lbs. 1,100 [O]

11. H. 1.2- Spain 5.7 ft 200 lbs. 1,000 2 sites Hunter 1997
antecessor 0.8 England [O] 2010

12. H.
cepranensis 0.9- Italy 1,000 1 skull 1994/03
0.8? cap

13. H.
heidelber- 0.6- Europe 5.9 ft. 130 ibs. 1,100- Many Hunter 1908
gensis 0.35 Africa 1,400 [A]
China

14. H. 0.35- Europe 5.2 ft 120- 1.200- Many Hunter (1829)/64


neanderthals 0.03 Western Asia 150 lbs. 1,900 [A]

15. H. 0.3-
rhodesiensis 0.12 Zambia 1,300 Very few 1921

16. H. 0.16- Ethiopia 1,450 3 craniums 1997/03


sapiens idaitu 0.15

17. H. 0.2- World wide 4.6- 110- 1,000- still living /1758
sapiens sapiens present 6.2 ft. 220 lbs. 1,850

* Eurasia Java, China, India, Caucasus Oldawom Phase I stone tools [O]
Cannibalism Acheulean Phase II stone tools [A]
Fire use 1 to 1.5 M BCE [Wikipedia]
THE PURPLE SEAL:: Breaking the Chronic Diseases and Syndromes: “The Great Pathophysiological
Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid, DNA & Protein in the
Aboriginal Vegan Genotype Human Body

Appendix A-3: The Ramifications of the Inventions of Hunting, Animal


Husbandry Agriculture and the Novel and Experimental
Carnivore and Omnivore Diets _ page 5-2

II. Inventory Table of Anthropogenic Extinct European and Asian Mega-Fauna

a.) Wooly Mammoth (Mammuthus primigenius) Europe circa 11,000 to 2,500 BCE

b.) Hairy Rhinoceros (Coelodonata antiquities) northern steppes of Eurasia circa 10,000 BCE

c.) Saber Tooth Tiger (Dinofelis diastemata) circa 1.2 M BCE

d.) Straight Tusked Elephant (Elephas Palaeoloxodon antiquus) circa 48,000 BCE

e.) Cave bear (Ursus spelaeus) Europe circa Pleistocene

f.) Cave Hyena (Crocuta crocuta spelaea) circa Pleistocene

g.) Cave Lion (Panthera leo spelaea) circa Pleistocene

h.) European Hippopotamus (Hippopotamus antiquus) Europe circa 40,000 BCE

i.) Dwarf Hippopotamus (Hippopotamus minor) Cyprus circa Pleistocene

j.) Dwarf Hippopotamus (Hippopotamus creutzburgi) Crete, Greece circa Pleistocene

k.) Giant rhinocerous (Elasmotherium sibiricum) East. Europe & Central Asia circa 126,000 BCE

l.) Narrow-Nosed Rhinoceros (Dicerorhinus hemitoechus) northern Eurasia circa 40,000 BCE

m.) Merck’s rhinocerous (Stepnaorhinus kirchbergensis/) Europe (Britain to Russia) circa 40,000 BCE

n.) Steppe Wisent Bison Asia circa 6,000 BCE

o.) Giant Deer/Irish Elk (Megaloceros giganteus) Ireland, Ural Mountains circa 6,000 BCE

p.) Dwarf Elephants in the Mediterranean (Elephas Palaeoloxodon) Tilos Island (Mediterranean)
Several species on different Mediterranean islands circa 4,000 BCE

q.) Cave Goat (Myotragus balearicus) Balearic (Majorca and Minorca) Islands circa 3,000 BCE

r.) Giant Rabbit Balearic (Minorcan) Island circa Pilocene?

s.) Scimitar Cat (Homotherium) North Africa, Europe, Asia, North America 30,000 BCE

t.) Elephants North Africa circa ?

u.) Dwarf Elephant Europe circa 2000 BCE

v.) Elephant Syria circa 100 BCE

w.) Aurochs (Wild cattle) (Bos primigenius primigenius) Poland, Europe, Eurasia circa 1627 CE

x.) Stellers’s Sea Cow (Sirenians) Commander Islands circa 1768 CE

y.) Wild Horse/Tarpan (Equus ferus ferus) Eurasia circa 1909

z.) Giraffe Europe circa ?

[Wikipedia]
THE PURPLE SEAL:: Breaking the Chronic Diseases and Syndromes:
“The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA & Protein in the Aboriginal Vegan Genotype Human Body

Appendix A-3: The Ramifications of the Invention of Hunting, Animal Husbandry


Agriculture and the Novel and Experimental Carnivore and
Omnivore Diets _ page 6

A.) WORLD OFF AXIS

Conventional science acknowledges that the earth magnetic poles do not coincide with its
rotational poles by a varying up to 24 degrees and thus wobbles but rejects the scenario put
forward by the Ancient Egypt/Kemit School of On (Annu or God) teachings that earth has
flipped over 3 times and is negatively charged as the positive end of a compass points north. An
analysis of the north pole charges of the other 8 Sun solar system planets is presented in detail on
http://www,theuniversityofgod.org/Page2.html confirmed by NASA analysis.

B.) WORLD FLIPS UPSIDE DOWN

Conventional sciences and technologies now acknowledges that the earth poles have made several
magnetic polar shifts but totally rejects the Ancient Egypt/Kemit School of On (Annu or God)
teachings that earth has flipped over 3 times as presented in detail on
http://www,theuniversityofgod.org/Page2.html. This was written by the Greek Father of History
Herodotus who studied there, recorded in the Bible consolidated as one flood and part of Ancient
Mesopotamia’s mythology. This rejection and skepticism of aboriginal knowledge is suspicious as
the Ancient Egypt/Kemit School of On (Annu or God) which followed and taught the Great Law
of Vegan Human Diet constructed the 1.) Sphinx and Temples and 2.) the Great Pyramids at Giza
which served as its main campus. These two ancient engineering marvels modern conventional
science and engineering technology can not explain nor copy yet those who built them were very
aware of the cause of the Quaternary Ice Age.

II.) LOSS OF HUMUS TOP SOIL DESERTIFICATION AND DEFORESTATION

There has been a second source of the decrease in CO2 revealed in the course of the Quaternary
Ice Age. That was when smart Europeans invented domesticated animals and agriculture based
on them. They had hunted the wild animals to extinction in Europe but not in Africa where the
blacks were following the vegan life style still. So by being smart and inventing domesticated
animals they would eat as the center of their growing vegetables, grains and fruit. This invention
has also taken over the world eclipsing the Garden of Eden earthworm based Sustainable
Horticulture Forestry model detailed on http://www.theunoiversityofgod.org/Page5.html.

But the domesticated animals destroy the top soil by pulling the plants out of the soil and trampling
what plants are left. The resulting top soil erosion means it runs off into the sea and fresh water
lakes. The micro-plants in the ocean the plankton and the larger sea weeds have all this nitrogen
rich top soil at the bottom of the oceans and they reproduce at a greater rate than they should or
would otherwise. They need CO2 to survive being plants and this is the second source for the
decrease in CO2 which has been going on for 3 million years and the clever Europeans and those
following their hunting and meat eating lifestyle can not figure out what has gone wrong.

The biological invention of domesticated animals and animal husbandry agriculture has
significantly contributed to 4/5 of the earth’s land being a ice and sand desert simply because the
cud chewing domesticated cows, goats and sheep destroy the top soil holding plants while grazing.
This process continues in America and all other planetary countries because of the insistence of
following the non-sustainable Omnovore Diet and Animal Husbandry based Agriculture that now
uses Agri-Chemical fertilizers instead of animal manures and producing humus top soil as an
unnecessary expensive hindrance to profit making.

III.) LOSS OF BLACK SKIN COLOR TO BROWN AND YELLOW SKIN COLOR BY THOSE
EUROPEAN AND ASIAN PEOPLES FOLLOWING THE NOVEL OMNIVORE DIET

Esoterically, it has been shown that the world’s modern humans of the species Homo Sapiens Sapiens
have maternal mitochondrial DNA traceable to somewhere in Eastern Africa at about 200,000 BC. It is
accepted that their aboriginal skin color was black from the Melanin skin pigmentation protection from the
Equatorial sun Ultra-Violet damage.

About 50,000 BC. there was a major migration of the world’s modern humans of the species Homo Sapiens
Sapiens out from Africa north into Europe and Asia eventually replacing the established hominids there
including Homo-erectus, Homo sapien, Cro-Magum and Neantherthal the later extinct by 28,000 BC.
THE PURPLE SEAL:: Breaking the Chronic Diseases and Syndromes:
“The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA & Protein in the Aboriginal Vegan Genotype Human Body

Appendix A-3: The Ramifications of the Invention of Hunting, Animal Husbandry


Agriculture and the Novel and Experimental Carnivore and
Omnivore Diets _ page 7

Esoterically, because of the decreasing Ultra-Violet radiation from the Equatorial sun it is theorized that
these Hominids in Europe and Asia having invented the novel Omnivorous Diet in turn developed a
lighter brown skin color from their aboriginal black skin color coming out of Africa being further away
than closer to the primary skin color determinate the Equatorial sun and its Ultra-Violet radiation producing
the nutritionally vital Vitamin E and Melanin as protection.

IV.) LOSS OF BROWN SKIN COLOR TO WHITE SKIN COLOR BY THOSE FOLLOWING
THE DEMONIC CARNIVORE DIET

It is crucial to understand that in the early Quaternary Period in Europe and West Asia the demonic Priestly
proponents of the novel Carnivore Diet were convinced that by inventing and following the new lifestyle of
“human as carnivore hunters” as opposed to the aboriginal lifestyle of “human as vegan/herbivore
gatherers” in the Garden of Eden forests it would propel them to be Supreme Human Beings. This
originated in the early Quaternary Period phenomena of hominid mutations that resulted from
experimentation with the Carnivore Diet that resulted in the novel phenomena of white skin colored
hominids.

A. NEANDERTHAL MUTATION OF PALE WHITE SKIN

It has been established from fecal analysis that the Homo Neanderthals were notorious “mammalian
cannibals” including ingesting other hominids including its own species “human cannibals.” Recent
discovery has established that Homo Neanderthals a sub-species of Homo Erectus had lighter than brown
skin color including pale white skin and red hair color from Melanocortin 1 Receptor Allele
[MC1R or melanocyte-stimulating hormone receptor (MSHR)] gene mutations.

The 1995 landmark study by P. Valverdie, et al, “Variants of the melanocyte-stimulating hormone
receptor gene are associated with red hair and fair skin in humans”, Nat. Genet. V. 11, N. 3, pp 328-
30, 1995 demonstrated that 80% of the people with red hair or fair skin have a dysfunctional variant of
the MC1R gene that is unusually predominant in northern populations specifically from Britain and
Ireland. There is no reasonable theory for this phenomena.

MC1R is located on the plasma membrane of the skin melanocytes and is the key protein in regulating
black and brown eumelanin and if activated generates the yellow or red phaeomelanin.

The recent 2010 Neanderthal Genome Mapping Project results showing humans shared at
least 20% of their genes would explain the British and Irish people today with the dysfunctional
variant of the MC1R gene. Consequently, it is hypothesized that Homo Neanderthals’ breakage of
the Great Law of Vegan Human Diet that applied to all hominids inheriting the maternal
mitochrondrian DNA genome biologicals as did Homo Neanderthals lead to the mutation of their skin
color genes including the MC1R Gene Allele.

B. EUROPEAN HOMO SAPIEN SAPIEN MUTATION FROM BROWN TO WHITE SKIN


From the hypothesis herein of The Purple Seal text Section VII page 31 “Mammalian
Cannibalism” including other hominids was practiced via the extreme Carnivore Diet by the
Homo Sapien Sapiens European sub-species as pioneered by their older cousins the Homo
Neanderthals that produced the latter’s unique white skin color and red hair. But the Homo
Sapien Sapiens European sub-species went a step further by experimenting and improving upon
the Carnivore Diet with the invention of Animal Husbandry Based Agriculture with its tbi-fold
biological inventions of a.) domesticated animals; b.) dairy products and c.) cereal grains.
THE PURPLE SEAL:: Breaking the Animal Dietary Cholesterol and DNA Related Diseases and Syndromes:
“The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA & Protein in the Aboriginal Vegan Genotype Human Body

Appendix A-3: The Ramifications of the Invention of Hunting, Animal Husbandry


Agriculture and the Novel and Experimental Carnivore and
Omnivore Diets _ page 8

THE FOLLOWING ARE “SLC24A5 Gene” NOTES from Wikipedia with emphasis added:

“Sodium/potassium/calcium exchanger 5 (NCKX5) also known as solute carrier family 24 member 5 (SLC24A5)
[1]
is a protein that in humans is encoded by the SLC24A5 gene that has a major influence on natural skin colour variation. The
NCKX5 protein is a member of the potassium-dependent sodium/calcium exchanger family. Sequence variation in
theSLC24A5 gene, particularly a non-synomyous SNP changing the amino acid at position 111 in NCKX5
from alanine to threonine, has been associated with differences in skin pigmentation.[2] “

GENE

The SLC24A5 gene, in humans, is located on the long (q) arm of chromosome 15 on position 21.1, from
base pair 46,200,461 to base pair 46,221,881.[1]
PROTEIN

NCKX5 is 43 kDa protein that is partially localized to the trans-Golgi network in melanocytes. Removal of the NCKX5 protein
disrupts melanogenesis in human and mouse melanocytes, causing a significant reduction in melanin pigment

production. Site-directed mutagenesis corresponding to a non-synonymous single nucleotide polymorphism in SLC24A5 alters a
[2]
residue in NCKX5 (A111T) that is important for NCKX5 sodium-calcium exchanger activity.

EFFECT ON SKIN COLOR


SLC24A5 appears to have played a key role in the evolution of light skin in humans of European ancestry. The gene's function in
pigmentation was discovered in zebrafish as a result of the positional cloning of the gene responsible for the "golden" variety of this

common pet store fish. In this work, cancer geneticist Keith Cheng used electron microscopy to characterize the cellular mechanism
underlying the lighter color of golden zebrafish, and noted a striking similarity between the changes of melanocytes (pigment

cells) in those lighter-skinned fish and lighter-skinned humans (in particular, Europeans). This led Cheng to ask his Pennsylvania

State University colleague, anthropologist Mark D. Shriver, whether he had human DNA linked to skin color measurements. Shriver,
who collaborates internationally to study the basis of variation in human skin color and other features in human populations, pointed
to the then-*new International HapMap Project database of genetic variation in human populations, and found that the gene has a
single "coding" polymorphism - one that changes an amino acid. The two primary alleles differ in only one nucleotide,

changing the 111th amino acid from alanine to threonine, abbreviated "A111T".[1][3][4]

The threonine allele was present in 98.7 to 100% among several European samples, while the alanine form was found in 93 to

100% of samples of Africans, East Asians and Indigenous Americans. The variation is a SNP polymorphism rs1426654, which had
been previously shown to be second among 3011 tabulated SNPs ranked as ancestry-informative markers. Collaborator Victor

Canfield plotted the human data to estimate that this single change in SLC24A5 explains between 25 and
38% of the difference in skin melanin index between peoples of West African vs. European Ancestry.

The discovery of this gene has interesting social implications because the "derived" European allele was

derived by mutation from the ancestral gene sequence. As noted by Penn State's Victor Canfield, the ancestral
alanine is conserved in all vertebrates sequenced to date, mutant only in the European allele, but only rarely in West African or

East Asian (primarily Chinese, Japanese and Korean) populations (presumably by admixture). Furthermore, the European

mutation is associated with the largest region of diminished genetic variation in the CEU HapMap population, suggesting the
possibility that the A111Tmutation may be the subject of the single largest degree of selection in human populations of

European ancestry. Selection for the derived allele is based on the need for sunlight to produce the essential nutrient vitamin D.

In northerly latitudes, there is less sun, greater requirement for body coverage due to colder climate, and frequently, diets poor in
vitamin D, making lighter skin necessary for survival. Tests for this variation has obvious application to forensic science.

It has been estimated that the threonine allele became predominant amongst Europeans 5,300 to

12,000 years ago.[5 ] Alanine is a non-essential amino acid while threonine is a essential amino acid and both

are abundant in animal “pseudo” food and dairy proteins.


THE PURPLE SEAL:: Breaking the Animal Dietary Cholesterol and DNA Related Diseases and Syndromes:
“The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol, Bile Acid,
DNA & Protein in the Aboriginal Vegan Genotype Human Body

Appendix A-3: The Ramifications of the Invention of Hunting, Animal Husbandry


Agriculture and the Novel and Experimental Carnivore and
Omnivore Diets _ page 9

The above “SLC24A5 Gene NOTES” from Wikipedia are consistent with the
hypothesis presented herein that the European Caucasian sub-species’ white
skin color mutation was associated with the novel and experimental Carnivore
Diet; i.e. the invention of domesticated animals is believed to have occurred
circa 10,000 years ago or 8,000 BCE.

Specifically, it is the abnormal human ingestion of mammal animal DNA that leads to white
skin mutations from an aboriginal black or brown skin color as sunlight ultra violet radiations
will lead to several nucleic base mutations as follows:

1.) purine base mutagens; and

2.) pyrimidine base mutagens.

both with the ability to change the following Alanine to Threonine amino acid codons of
Guanine to Adenine as follows:
RNA DNA

Alanine codons are GCU GCT GC_ Guanine (G, Purine)

GCA GC_

GCC GC_

GCG GC_

Threonine codons are ACU ACT AC_ Adenine (A, Purine)

ACA AC_

ACC AC_

ACG AC_

Esoterically, the creation of the European White Race was spawned by a demonic
White Supremacy mythology. This errant mythology had its origin in the older evil
human cannibal Homo Neanderthales who appeared circa 350,000 BCE and died out at
circa 28,000 BCE. In circa 200,000 BCE their aboriginal brown skin color was changed to
the novel white skin color from a melanocyte MC1R gene mutation from their
experimentation with the Carnivore Diet. Evidently in order to live with this accident it was
necessary for the Sorcerer Priest and Priestess proponents of the Carnivore Diet to
rationalize their “mark of the breast” white skin color as a White Supremacy mythology.

Consequently, it is not a coincidence that the later circa 60,000 BCE appearing Homo
sapien sapien European sub-species were also aboriginally brown skin colored and from a
different melanocyte SLC24A5 gene mutation to white skin circa 3,300 to 10,000 BCE
experimenting with the Carnivore Diet and the novel invention of domesticated animals
circa 8,000 BCE. The white skin Homo sapien sapien European sub-species karma from
this mutation is the continued predilection and significant incidence to skin cancer
especially melanoma. The Vegan Diet coupled to internal cleansings as outlined in the
Purple Seal Section VII will reverse this white skin Homo sapien sapien European sub-
species karma.
Tropical Medicine and International Health

volume 8 no 7 pp 581–584 july 2003

Editorial: Iatrogenic poverty


Bruno Meessen1, Zhang Zhenzhong2, Wim Van Damme1, Narayanan Devadasan1, Bart Criel1 and Gerald Bloom3

1 Institute of Tropical Medicine, Antwerp, Belgium


2 Chinese Health Economics Institute, Beijing, China
3 Institute of Development Studies, Brighton, UK

keywords poverty, iatrogenesis, catastrophic health care expenditure, health insurance, social
assistance, Asia, transition

Poverty and illness are intertwined. It is a well-documented worries (Milimo et al. 2002). Economists and experts in
fact that poverty leads to ill-health. In every society, poverty analysis have raised the issue. The WHO, the
morbidity and mortality are higher among the poor World Bank and the ILO are trying to put it higher on the
(Wagstaff 2002). Determinants of lower health status agenda by referring to it as catastrophic health care
include nutrition, environment, education, lifestyle and expenditure. But the issue is still little recognized by the
access to health care. Less is known about how illness itself political, scientific and, most of all, the medical commu-
can lead to poverty in developing countries. There are two nities. Doctors are trained to assess the outcome of their
major pathways. The first is through the death or disability interventions in terms of health status, it is high time to
of a household income earner. This reduces future income consider them in terms of welfare.
generation and may jeopardize household consumption. Let us have a look at the world outside the health sector.
After a household has depleted its wealth it may have less What has been the major change for humanity these last
capacity to invest in the education of their children. This two decades? The average reader of this journal might
transmits poverty to the next generation. identify globalization. But for 1.7 billion people, the major
The second is through the treatment itself, or more change has another name: transition. The transition from a
exactly its cost. The chain of events is as follows: when planned economy to a market economy has concerned
someone falls ill, the household faces several different costs China, most of South East Asia, Eastern Europe and the
(opportunity cost of care giving, transportation, treat- Republics of the former Soviet Union. What has this
ment), and to cope with them, it follows diverse strategies. transition meant for the citizens of these countries?
Sometimes the costs are limited, and the household is able Economic growth in some countries, but also a reshaping
to buffer them by making a short-term adjustment (such as of the pattern of entitlements (Sen 1981). While education,
consuming precautionary saving, calling on assistance from jobs, income and welfare services used to be taken for
informal support networks, temporarily reducing its con- granted, today they are determined by a combination of
sumption of other goods). Yet, sometimes, the costs are at, market forces and political commitment to provide bene-
or increase to, a level where these coping mechanisms are fits. One can find a job and earn an income according to
not sufficient anymore. The household then adopts the one’s skills and the demand in the labour market. Access to
riskier strategies of selling or mortgaging its productive education and health care are no longer universal, but are
assets (Ensor & Bich San 1996; Bloom & Lucas 2000; influenced by the ability to pay.
Meessen & Criel 2003). Some households recover from the Most governments fail to fund their health sector
financial shock, but others do not (Wilkes et al. 1997). The adequately because of limited budgets, excessive faith in
next time when they have to deal with an illness, a crop market forces or other priorities. Consequently, many
failure or another problem, they may be tipped into public health care facilities are run down or they generate
poverty. Chambers (1983) has called this process a poverty revenue by charging patients. At the same time, rural
ratchet. households in many countries have a new opportunity to
mortgage or sell their land and other productive assets.
ÔMarketizationÕ is indeed ubiquitous. Today, more than
Iatrogenic poverty
ever, the Cambodian or Chinese farmer is able to
Poor people are well aware of that cycle. Surveys have match his ability to pay for health care with his willing-
found that they identify sickness as one of their greatest ness to pay. Credit and land markets, i.e. usurious

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B. Meessen et al. Iatrogenic poverty

moneylenders and resourceful neighbouring farmers, are ineffective therapies, consumption of savings, indebted-
there to ÔhelpÕ. ness, sale of productive assets and eventually poverty. The
Is this problem limited to transitional countries? Cer- disease does not have to be a complex one; dengue in
tainly not. The problem is also important in Asian Cambodia can be enough (Van Leemput & Van Damme
countries with less dramatic changes, such as India or 2002). There, health care costs are reported today as the
Indonesia (Gertler & Gruber 2002). Many years ago single most important reason for households to fall into
Chambers (1983) suggested that the development of poverty (Kassie 2000). China’s policy-makers also
modern hospitals was a major source of difficulties for the acknowledge that illness of a family member has become
rural poor, who have been made to choose between letting one of the most important causes of household poverty
a sick parent die without care on the one hand and (Zhang 2002). Poverty induced by medicine – Ôiatrogenic
impoverishment because of high health care costs on the povertyÕ!
other (G. Bloom personal communication). The AIDS
epidemic has made these choices even more agonizing.
The search for solutions
The whole problem cannot be explained by the rising
liquidity of household assets alone. Willingness to pay is The main recommendation for protecting people against
also increasing. Because of economic growth, epidemiolo- the high cost of illness is social insurance (Kawabata et al.
gical transition, the ageing of the population and access to 2002). Disease is a lottery and households can insure their
information, there is an emerging demand in low- and welfare by pooling their risks and resources. Everyone
middle-income countries for treatments similar to those shares the cost of the unlucky ones who fall ill. The benefits
delivered in rich countries. Many are ready to try out are obvious: people can insure against health care expen-
anything for their loved ones. diture (social health insurance) and also the loss of income
The supply side follows demand: medical progress – because of death or invalidity (widow, orphan and
mainly drugs and imaging technology – penetrates liber- disablement benefits). Several generations of citizens of the
alizing markets easily. In a country like China, the health advanced market economies have enjoyed the blessings of
staff are understandably eager to increase their income and social security. In some low- and middle-income countries,
keep themselves in line with the other dynamic sectors of statutory social health insurance exists but often only for a
the economy. They face few regulatory constraints. This minority of the population: those working in the formal
unique convergence of factors is creating a real business in sector. Hence, there is a growing interest in voluntary
health care. Health is one of the fast growing sectors in health insurance schemes targeting households that live on
transition economies. For example, since 1996, the annual agriculture or make a living in the informal sector (Criel &
growth rate of health expenditure in China has been more Kegels 1997; Bennett et al. 1998; Carrin 2002; Ranson
than 13%, significantly exceeding the already fast-growing 2002).
economic growth rate (Zhao 2002). Yet, we must not be lured into complacency. It will
Is this impressive growth justified by needs? Only partly. probably take years, if not decades, for these voluntary
A major feature of the health care market is asymmetry of health insurance schemes to consolidate and go to scale
information: as far as diagnosis and treatments are (Meessen et al. 2002a). Moreover, if they are not well-
concerned, the patient is at the mercy of his agent, the designed, for instance in terms of provider payment
health worker. Many health workers get their knowledge modalities, they will contribute to rapid cost escalation.
from the people who sell them drugs. To control the risk of Other strategies are needed to keep costs under control.
provider-induced consumption, a full toolbox of institu- A lot can be done with some basic measures to eliminate the
tions has been developed over the ages, ranging from worst prescription practices. Some forms of rationing by
market regulation to what we can club together under the defining of packages of basic services is also unavoidable.
term ÔprofessionalismÕ. Many Asian countries in transition A full array of measures exists to change the behaviour of
lack these set of mechanisms. Traditionally, providers were providers. It has to do with empowering actors (e.g.
only accountable to the state which had a ubiquitous patients, through health care education, formulation of
presence (as an owner, supplier, employer, manager and patient rights and the emergence of family medicine), with
payer). With transition, the grip of these mechanisms is new institutional arrangements (e.g. registration, accredi-
losening. Unprotected by checks and balances, the patients tation, professional bodies, and enforcement of rules
are today at the mercy of health workers who, for against inappropriate behaviour), and also with the inter-
historical reasons, often have very limited medical know- nalization of new norms by practitioners (medical ethics).
ledge. This fuels a vicious circle: distress caused by disease, Once we recognize the harm that bad medical practice does,
the quest for treatment – often through a succession of the need for health sector reforms becomes apparent.

582 ª 2003 Blackwell Publishing Ltd


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B. Meessen et al. Iatrogenic poverty

Is the combination of ambitious social health insurance increasingly important that the poverty dimension is
programmes and reforms of health care provision sufficient integrated into health policies and in the medical practice.
to address the problems of health care-induced poverty? In 1975, Ivan Illich put iatrogenic disease on the profes-
We do not think so. Health insurance is an option for those sion’s agenda (Wright 2003). Now shortly after his death,
able to pay the insurance premiums, but what about the it is time to recognize a new form of iatrogenic suffering:
poor? poverty induced by doctors. This is not only a matter of
There is a need for a straightforward transfer of human rights, but also of public health. When someone
resources to the poor. European history has shown that falls ill it may bankrupt an entire household and expose its
even the affluent can gain from such income redistribution members to an increased risk of further ill-health. Poor
(de Swaan 1988). If social security is the option for the medical practice and the lack of financial protection
majority, the poor need a targeted transfer – social increases the negative impact of ill-health. This is a real
assistance (Norton et al. 2001). The creation of effective vicious circle. We need to do something about it.
safety nets is not simple in terms of institutional arrange-
ments. It entails addressing the following challenges:
References
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beneficiaries and delivering services that answer the specific Bennett S, Creese A & Monasch R (1998) Health Insurance
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Ensor T & Bich San P (1996) Access and payment for health care:
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initiatives and they have many problems to solve. But they The American Economic Review 92, 51–70.
deserve attention from the scientific and donor community. Kassie A (2000) Credit and Landlessness: Impact of Credit Access
Fighting iatrogenic poverty calls for more than just on Landlessness in Cheung Prey and Battambang Districts,
establishing some kind of social health insurance. It should Cambodia. Center for Advanced Studies, Phnom Penh.
be strongly emphasized that the solution lies to a large Kawabata K, Xu K & Carrin G (2002) Preventing impoverishment
extent within the health sector; however, a wide coalition through protection against catastrophic health expenditure.
Bulletin of the World Health Organization 80, 612.
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Meessen B & Criel B (2003) Quelles stratégies de couverture face
ments, such as Ministries of Social Affairs, must be
aux risques liés à la santé? Quelques points de repère micro-
involved. Civil societies have a role to play. Programmes of économiques pour la réflexion sur les stratégies disponibles dans
social assistance will require a massive support by the les sociétés africaines et asiatiques. In: Financer la santé dans les
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with a better understanding of the exact relationship Meessen B, Criel B & Kegels G (2002a) Les arrangements
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Authors
Bruno Meessen, Dr Wim Van Damme, Dr Narayanan Devadasan and Dr Bart Criel, Institute of Tropical Medicine, Nationalestraat
155, 2000 Antwerp, Belgium. E-mail bmeessen@itg.be
Zhang Zhenzhong, Chinese Health Economics Institute, Peking University Medical Science Center, P.O. Box 218, 38 Xueyuan Road,
Haidian District, 100083, Beijing, China. E-mail zhangzzc@public3.bta.net.in
Gerald Bloom, Institute of Development Studies, University of Sussex, Brighton BN1 9RE, UK. E-mail G.Bloom@ids.ac.uk

584 ª 2003 Blackwell Publishing Ltd


APPENDIXE C.

Press Release and the Science Magazine, May 17, 2002 article by Makoto Makishima, PhD, et al,
“Vitamin D Receptor as an Intestinal Bile Acid Sensor.”
RESEARCHERS UNCOVER BIOCHEMICAL CONNECTION BETWEEN HIGH-FAT
DIETS AND INCREASED COLON-CANCER RISK

DALLAS – May 17, 2002 – Researchers at UT Southwestern Medical Center at Dallas have
uncovered what could be a key clue in tracing the connection between high-fat diets and
increased colon-cancer risk.

Their findings, published in today’s edition of Science, reveal that the body’s natural mechanisms
aren’t built to handle lithocholic acid, a toxic byproduct of dietary fat, in the volume generated
by high-fat diets.

Dr. David Mangelsdorf, professor of pharmacology and investigator in the Howard Hughes
Medical Institute (HHMI) at UT Southwestern, said observational evidence established a
strong association between high-fat diets and colorectal cancer, but scientists could not
explain the biological and biochemical mechanisms that formed the link.

“The rate of colorectal cancer is much higher in the United States - where a high-fat diet is
common - than in Japan, where people don’t eat a lot of fat and colorectal cancer is almost
nonexistent. But no one has understood why that is,” he said.

The new findings show that at least part of the answer lies in the body’s inability to cope with
large amounts of lithocholic acid, produced when the body processes cholesterol. The body
produces bile acids when it breaks down cholesterol, part and parcel of dietary fat. Those
bile acids go to the small intestine and are broken down into secondary bile acids, one of
which is lithocholic acid.

Most secondary bile acids circulate to the liver, but only a little bit of lithocholic acid does
so. Much of it remains in the small intestine, then moves into the colon, or large intestine.

“Lithocholic acid is highly toxic, and it builds up in a high-fat diet,” Mangelsdorf said. “We
don’t know how it causes cancer; but it is known to cause cancer in mice, and people with
colon cancer have high concentrations of it.”
Scientists knew that a certain receptor controlled the small amount of lithocholic acid
in the liver. Receptors are proteins that bind to certain substances to help the body
absorb or get rid of them. The lithocholic acid-controlling receptor also is present in
the colon. But there isn’t enough of it to cope with large volumes of lithocholic acid.

However, the lithocholic acid-controlling receptor is similar in structure to another receptor,


which binds to vitamin D to help the body absorb calcium. Mangelsdorf’s team wondered if the
vitamin D receptor might also help eliminate lithocholic acid.

The researchers discovered that the vitamin D receptor actually plays a major role in eliminating
lithocholic acid. Like the receptor that works in the liver, the vitamin D receptor binds to
lithocholic acid, then binds to a specific gene, called CYP3A that triggers production of an
enzyme that breaks down the toxic acid. Those findings were made using assays, which are
small, flat panels used to study genetic activity outside living organisms.

Next, the researchers used tissue cultures to show that the process is replicated in living cells.
Then, the team fed vitamin D and lithocholic acid to mouse models. The lithocholic acid
activated the animals’ CYP3A genes, as well as other genes that the vitamin D receptor is
known to bind to after binding with vitamin D.

“It turned out that in vivo, the vitamin D receptor appeared to play a large role in breaking down
lithocholic acid,” Mangelsdorf said.

While the research identifies a possible target for helping the body eliminate excess lithocholic
acid, exploiting the research might not be so simple. Taking extra vitamin D would stimulate
more activity in the vitamin D receptors, but that also would cause the body to absorb more
calcium. Ingesting too much vitamin D can lead to hypercalcemia, a toxic condition that
occurs with excessive calcium buildup.

Mangelsdorf said the body’s natural lithocholic acid-response mechanism simply wasn’t built
to handle the amount of fat in the modern American diet.

“Our bodies can handle slight changes in lithocholic acid that come from a normal diet, but
not a high-fat diet,” he said. “The current American diet can provide more fat on a daily
basis than a human being was ever meant to handle.”

Dr. Makoto Makishima, a former research associate in the HHMI at UT Southwestern, was lead
author of the study. Other UT Southwestern researchers who contributed were Timothy T. Lu,
an M.D./Ph.D. student in pharmacology, and Dr. Hideharu Domoto, a postdoctoral fellow in
pharmacology.

Other institutions contributing to the study were the Salk Institute for Biological Studies and
the University of Arizona College of Medicine. The study was supported by the Howard
Hughes Medical Institute, the National Institutes of Health, the Robert A. Welch
Foundation and the Human Frontier Science Program.
------------------------------------------------------------------------
© 2003 The University of Texas Southwestern Medical Center at Dallas Page maintained by:
Office of News and Publications. Last update: May 16, 2002
APPENDIXE D. Izrael Hieger, D. Sc., Research Articles and Book Extracts on
Dietary Cholesterol as Carcinogen, 1930-62

1.) 1930 E. L., Kennaway and Izrael Hieger, I, “Carcinogenic Substances and their Fluorescence Spectra,”
British Medical Journal, pp. 1044 – 46, June 7,

2.) 1930 Izrael Hieger, “The Spectra of Cancer Producing Tars and Oils and Related Substances,”
Biochemical Journal, V. 24 (2) pp. 505- 61,

3.) 1946 Izrael Hieger, “Carcinogenic Substances in Human Tissue,”


Cancer Research, V 6, pp 657- 67

4.) 1947 Izrael Hieger, “Carcinogenic Activity of preparations rich in Cholesterol,”


Nature, V. 160, pp 270- 71

5.) 1949 Izrael Hieger, “Carcinogenic Activity of Lipoid Substances,”


Bri. Journal of Cancer, V. 3, pp 123-39

6.) 1954 Izrael Hieger and S.F.D. Orr, “On the Carcinogenic Activity of Purified Cholesterol,”
Bri. Journal of Cancer, V. 8 (2), pp 274-90

7.) 1957 Izrael Hieger, “Cholesterol as a Carcinogen,”


Proceedings of the Royal Society, B (Biological Sciences), V. 147, pp 84-8

8.) 1958 Izrael Hieger, “Cholesterol Carcinogenesis,”


Bri. Medical Bulletin, V. 14, pp 159-160

9.) 1959 Izrael Hieger, “Carcinogenesis of Cholesterol,”


Bri. Journal of Cancer, V. 8 (3), pp 439-51

10.) 1960 Izrael Hieger, [Unknown article title]


Acta Unio Internationalis Contra Cancrum, V. 15, p. 603, Geneva, Switzerland

Note: This article was so suppressed its “Title” is not retrievable on the Internet, its paper journal resides on
shelve in a few European University Libraries, the journal became defunct in 1964 and has not been
digitized and no abstract of the article exists.

11.) 1961 __ Extract from book by Hieger, Izrael, Carcinogenesis,


Academic Press, London, England, 1961

12.) 1962 Izrael Hieger, “Cholesterol as Carcinogen I. Sarcoma Induction by Cholesterol in a Sensitive
Strain of Mice,” British Journal of Cancer, V 16 (4) pp 716-21
APPENDIXE E.

Dean Ornish, MD. editorial “Mostly Plants” in Journal of American Cardiology, May, 2009
Mostly Plants
Dean Ornish, MDa,b,*

Eat food. Mostly plants. Not too much. based diet), they often feel so much better, so quickly, that
1
—Michael Pollan, The Omnivore’s Dilemma it reframes the reason for making these changes from fear of
dying, which usually is not sustainable, to joy of living,
There is a growing convergence of scientific evidence which often is.
that an optimal diet is mostly plant based, consisting pre- Evidence suggests that a plant-based diet is beneficial for
dominantly of fruits, vegetables, whole grains, legumes, and preventing and treating a variety of chronic diseases. In
soy products. A healthful diet is also low in refined carbo- addition to the effects of a plant-based diet on hypercholes-
hydrates, saturated fat, and trans fats and high in complex terolemia, these include coronary artery disease, diabetes,
carbohydrates with adequate omega-3 fatty acids.2 hypertension, obesity, prostate cancer, breast cancer, and
In this issue, Kottler et al3 review studies indicating that other conditions. In other words, it is not 1 diet for heart
a plant-based diet combined with nuts, soy, and/or fiber disease, another for diabetes, and another for hypercholes-
reduces low-density lipoprotein (LDL) cholesterol by an terolemia. A reason that these conditions are often associ-
average of 25% to 30%. This is comparable to what can be ated is that they often share common diet and lifestyle
achieved with statin drugs but without the costs and poten- origins.
tial side effects. Last year, almost $20 billion was spent on The National Institutes of Health and AARP study of
statin drugs in the United States. At a time when health care 500,000 subjects reported that the consumption of red meat
reform is at center stage, the potential cost savings of re- was significantly associated with increases in total mortal-
ducing the need for statin drugs by changing diet and life- ity, cardiovascular mortality, and cancer mortality.7 Mea-
style is of great interest. sures of cardiovascular disease such as flow-mediated va-
When most patients are diagnosed with hypercholester- sodilation as well as LDL cholesterol and inflammation
olemia, they are usually advised to follow the dietary guide- worsened on a typical Atkins diet but improved significantly
lines of the American Heart Association or the National on a low-fat, whole-foods, plant-based diet.8
Cholesterol Education Program. However, these moderate What we include in our diet is as important as what we
changes in diet usually result in only modest reductions in exclude. Plant-based foods contain ⱖ100,000 disease-pre-
LDL cholesterol levels,4 at which point lipid-lowering drugs venting nutrients, such as phytochemicals, bioflavonoids,
are usually prescribed. Most patients are not given the carotenoids, retinols, isoflavones, genistein, lycopene, poly-
option of making more intensive changes in diet and life- phenols, sulforaphanes, and so on.9 They are also low in
style such as a plant-based diet, because of the belief that disease-promoting constituents such as saturated fats, trans
they will not follow them.5 fatty acids, dietary cholesterol, and sugar.
This belief often becomes self-fulfilling. “Mr. Jones, For example, blueberries contain phytochemicals called
your LDL cholesterol level is elevated. I know you wouldn’t anthocyanins that may improve memory. Tomatoes are rich
follow a plant-based diet or even a modified plant-based in lycopene, an antioxidant that may help reduce the risk for
diet, and why would you want to when I can give you a coronary artery disease, breast cancer, lung cancer, and
statin drug and that will do it?” So the patient takes the drug, prostate cancer. Ginger contains a compound called gin-
does not change his diet, and the doctor says, “See, I knew gerol that may lower blood pressure and increase circula-
he couldn’t change his diet.” tion. Pomegranates are rich in phytochemicals that may help
The idea that taking a pill is easy and that most patients prevent prostate cancer by reducing deoxyribonucleic acid
will adhere whereas changing diet and lifestyle is difficult if damage and may increase myocardial perfusion in those
not impossible is not supported by most studies. In fact, with ischemic heart disease.10 Kale contains luting, an an-
research shows that up to 60% of patients prescribed lipid- tioxidant that protects against macular degeneration.
lowering drugs are not taking them only 6 months after Studies are showing that although isolated vitamins may
initiating treatment.6 Why? Because patients are asked to not be beneficial, plant-based foods that contain these vita-
take a pill that does not make them feel better in the hope of mins often are protective. For example, ␤-carotene supple-
preventing something frightening, such as a myocardial ments were found to increase the risk for lung cancer in
infarction or stroke, which most people do not want to think smokers, whereas foods such as carrots that are rich in
about, so they usually do not. ␤-carotene were found to lower the risk.11
However, when people make comprehensive lifestyle In our studies, my colleagues and I at the nonprofit
changes, including a plant-based diet (or a modified plant- Preventive Medicine Research Institute, in collaboration
with other institutions, found that a plant-based diet (along
a with moderate exercise, such as walking 30 minutes/day,
Preventive Medicine Research Institute, Sausalito, California; and
b
University of California, San Francisco, San Francisco, California. Manu-
stress management techniques such as meditation and yoga,
script received April 20, 2009; revised manuscript received and accepted and increased social support) was able to stop or reverse the
May 13, 2009. progression of even severe coronary artery disease as mea-
*Corresponding author: Tel: 415-332-2525; fax: 415-332-5730 sured by exercise thallium scintigraphy,12 radionuclide ven-
E-mail address: dean.ornish@pmri.org (D. Ornish). triculography,13 cardiac positron emission tomography,14

0002-9149/09/$ – see front matter © 2009 Published by Elsevier Inc. www.AJConline.org


doi:10.1016/j.amjcard.2009.05.031
958 The American Journal of Cardiology (www.AJConline.org)

and quantitative coronary arteriography.15 There was even 2. Ornish D. The Spectrum. New York: Ballantine, 2008:386.
more improvement after 5 years than after 1 year, and there 3. Kottler BM, Ferdowsian HR, Barnard ND. Effects of plant-based diets
on plasma lipids. Am J Cardiol 2009;104:947–956.
was a direct correlation between the degree of change in diet 4. Hunninghake DB, Stein EA, Dujovne CA, Harris WS, Feldman EB,
and lifestyle and the degree of improvement in percentage Miller VT, Tobert JA, Laskarzewski PM, Quiter E, Held J, Taylor AM,
diameter stenosis. Also, we found 2.5 times fewer cardiac Hopper S, Leonard SB, Brewer BK. The efficacy of intensive dietary
events.16 We conducted a randomized controlled trial indi- therapy alone or combined with lovastatin in outpatients with hyper-
cating that the progression of early-stage prostate cancer cholesterolemia. N Engl J Med 1993;328:1213–1219.
5. Ornish D. Statins and the soul of medicine. Am J Cardiol 2002;89:
was slowed, stopped, or reversed in patients who followed
1286 –1290.
a plant-based diet and lifestyle intervention.17 6. Liberopoulos EN, Florentin M, Mikhailidis DP, Elisaf MS. Compli-
We are gaining a greater understanding of some of the ance with lipid-lowering therapy and its impact on cardiovascular
genetic mechanisms by which these diet and lifestyle morbidity and mortality. Expert Opin Drug Saf 2008;7:717–725.
changes are beneficial. For example, we found that this 7. Sinha R, Cross AJ, Graubard BI, Leitzmann MF, Schatzkin A. Meat
intervention caused beneficial changes in gene expression in intake and mortality: a prospective study of over half a million people.
Arch Intern Med 2009;169:562–571.
⬎500 genes in only 3 months, upregulating disease-pre- 8. Miller M, Beach V, Sorkin JD, Mangano C, Dobmeier C, Novacic D,
venting genes and downregulating oncogenes that promote Rhyne J, Vogel RA. Comparative effects of three popular diets on
breast cancer and prostate cancer and also downregulating lipids, endothelial function, and C-reactive protein during weight
genes that promote inflammation and oxidative stress, maintenance. J Am Diet Assoc 2009;109:713–717.
which often contribute to the cause and progression of 9. Dewell A, Weidner G, Sumner MD, Chi CS, Ornish D. A very low-fat
vegan diet increases intake of protective dietary factors and decreases
coronary artery disease.18 We also found that these lifestyle intake of pathogenic dietary factors. J Am Diet Assoc 2008;108:347–
changes increased telomerase, the enzyme that lengthens 356.
telomeres, the ends of our chromosomes that affect longev- 10. Sumner MD, Elliott-Eller M, Weidner G, Daubenmier JJ, Chew MH,
ity.19 Even drugs have not been shown to do this. Marlin R, Raisin CJ, Ornish D. Effects of pomegranate juice consump-
Also, what’s good for you is also good for our planet. tion on myocardial perfusion in patients with coronary heart disease.
Animal agribusiness generates more greenhouse gases than Am J Cardiol 2005;96:810 – 814.
11. Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR,
all transportation combined.20 The livestock sector gener- Glass A, Keogh JP, Meyskens FL, Valanis B, Williams JH, Barnhart
ates more greenhouse gas emissions as measured in carbon S, Hammar S. Effects of a combination of beta carotene and vitamin
dioxide equivalent than transportation (18% vs 13.5%). A on lung cancer and cardiovascular disease. N Engl J Med 1996;334:
Also, it accounts for 9% of the carbon dioxide derived from 1150 –1155.
human-related activities. It generates 65% of the human- 12. Ornish DM, Gotto AM, Miller RR, Rochelle D, McAllister GK.
Effects of a vegetarian diet and selected yoga techniques in the treat-
related nitrous oxide, which has 296 times the global warm- ment of coronary heart disease. Clin Res 1979;27:720A.
ing potential of carbon dioxide. It is also responsible for 13. Ornish DM, Scherwitz LW, Doody RS, Kesten D, McLanahan SM,
37% of all the human-induced methane, which is 23 times Brown SE, DePuey E, Sonnemaker R, Haynes C, Lester J, McAllister
more warming than carbon dioxide. Nitrous oxide and GK, Hall RJ, Burdine JA, Gotto AM Jr. Effects of stress management
methane mostly come from manure, and 56 billion “food training and dietary changes in treating ischemic heart disease. JAMA
animals” produce a lot of manure each day. Also, livestock 1983;249:54 –59.
14. Gould KL, Ornish D, Scherwitz L, Brown S, Edens RP, Hess MJ,
now use 30% of the earth’s entire land surface, mostly for Mullani N, Bolomey L, Dobbs F, Armstrong WT, Merritt T, Ports T,
permanent pasture but also including 33% of global arable Sparler S, Billings J. Changes in myocardial perfusion abnormalities
land to produce feed for them. As forests are cleared to by positron emission tomography after long-term, intense risk factor
create new pastures, it is a major driver of deforestation: modification. JAMA 1995;274:894 –901.
some 70% of forests in the Amazon have been turned over 15. Ornish DM, Brown SE, Scherwitz LW, Billings JH, Armstrong WT,
Ports TA, McLanahan SM, Kirkeeide RL, Brand RJ, Gould KL. Can
to grazing. lifestyle changes reverse coronary heart disease? The Lifestyle Heart
Finally, eating lower on the food chain is a more efficient Trial. Lancet 1990;336:129 –133.
way to produce protein. It takes significantly more resources 16. Ornish D, Scherwitz LW, Billings JH, Brown SE, Gould KL, Merritt
to produce meat-based protein than plant-based protein. As TA, Sparler S, Armstrong WT, Ports TA, Kirkeeide RL, Hogeboom C,
the earth’s population continues to increase and resources Brand RJ. Intensive lifestyle changes for reversal of coronary heart
disease. JAMA 1998;280:2001–2007.
decrease, choosing to eat more plant-based foods frees up
17. Ornish D, Weidner G, Fair WR, Marlin R, Pettengill EB, Raisin CJ,
more resources to help feed others. Knowing that the food Dunn-Emke S, Crutchfield L, Jacobs FN, Barnard RJ, Aronson WJ,
choices we make each day not only help ourselves and our McCormac P, McKnight DJ, Fein JD, Dnistrian AM, Weinstein J, Ngo
family but also our planet often brings a sense of meaning; TH, Mendell NR, Carroll PR. Intensive lifestyle changes may affect
for many people, this is a powerful motivator. the progression of prostate cancer. J Urol 2005;174:1065–1070.
Many people tend to think of breakthroughs in medicine 18. Ornish D, Magbanua MJ, Weidner G, Weinberg V, Kemp C, Green C,
Mattie MD, Marlin R, Simko J, Shinohara K, Haqq CM, Carroll PR.
as new drugs, lasers, or high-tech surgical procedures. They Changes in prostate gene expression in men undergoing an intensive
often have a hard time believing that the simple choices that nutrition and lifestyle intervention. Proc Natl Acad Sci U S A 2008;
we make in our lifestyles—what we eat, how we respond to 105:8369 – 8374.
stress, whether or not we smoke cigarettes, how much 19. Ornish D, Lin J, Daubenmier J, Weidner G, Epel E, Kemp C, Mag-
exercise we get, and the quality of our relationships and banua MJ, Marlin R, Yglecias L, Carroll PR, Blackburn EH. Increased
telomerase activity and comprehensive lifestyle changes: a pilot study.
social support— can be as powerful as drugs and surgery, Lancet Oncol 2008;9:1048 –1057.
but they often are. Sometimes, even better. 20. Food and Agriculture Organization of the United Nations. Livestock’s
Long Shadow: Environmental Issues and Options. Available at: http://
1. Pollan M. The Omnivore’s Dilemma: A Natural History of Four www.fao.org/docrep/010/a0701e/a0701e00.HTM. Accessed June 9,
Meals. New York, New York: Penguin, 1996. 2009.
APPENDIXE F.

George W. Singleton, HD. Holistic Reversal of Alzheimer’s Disease and Parkington’s Disease Dementia
PURPLE SEAL: BRCA, INC. MEMBERS AND DESIGNATED NETWORK
THE PURPLE SEAL:: Breaking the Animal Dietary Cholesterol and DNA Related Diseases and Syndromes:
“The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary Cholesterol,
Bile Acid, DNA & Protein in the Aboriginal Vegan Genotype Human Body

Appendix F
The Reversal of Alzheimer's Disease (AD), Parkington's Disease (PD) and Other Dementia

I. The Cause

One could wait a few more years until the allopathic and osteopathic medical communities admit they now know the
cause of the various manifestations of Dementia, or one could gain from the observational evidence that clearly points to
the ingestion of mammalian animal "pseudo-foods" (red meat) or "Mammal Cannibalism" as the culprit.
The aboriginal diet of humans beings (homo sapiens) is part of the Great Law called "General Human Systems
Theory (GHST)" which was written by Moses [alias Egyptian “School of On (Annu or God)” 18 th Dynasty
Egyptian/Kemitian Pharaoh Akhenaten] in the Book of Genesis 1:29 of the Hebrew Old Testament and Christian
Bible. Hereditary forms of Dementia simply means those with familial genomes that are more sensitive to red meat
"pseudo-food" ingestion and its “slow poisoning” effects than the rest of earth's human population.

II. The Proof

One has only to do comparative study of the Prion Protein Infectious Diseases to see the extreme results of "Mammal
Cannibalism;" i.e. as humans are mammals the possible consequences from eating from ones own family group the
domesticated or wild mammals. The Prion Protein Infectious Diseases include the following spongiform
encephalopathys (SE) amongst humans:
1.) Kuru from cannibalizing human flesh
2.) CJD (Creutzfeldt-Jacob Disease)
3.) GSS (Gerstmann-Strausler-Schewke Syndrome)
4.) fatal familial insomnia
5.) Iatrogenic CJD from failed surgeries of brain tissue, cornea grafts, administration of human growth hormone
6.) variant CJD from ingesting Bovine Spongiform Encephalopathy (BSE) contaminated cow meat

The Prion Protein Infectious Diseases include the following SE’s amongst the mammalian animals other than humans:
1.) BSE affecting cows (Bovine Spongiform Encephalopathy, "mad cow disease")
2.) Scrapie affecting sheep
3.) spongiform encephalopathys affecting wild moose and wild sheep

The SE’s are all “slow infectious diseases” taking a long time period to manifest into the symptoms of a.) dementia
and/or b.) "spongiform" holes in the brain tissue and/or c.) serious brain placque formations. They are all fatal
with no reversal possible using the conventional allopathic or osteopathic medical paradigm.

One simply has to comparatively look at the etiology of Kuru amongst the Fore people of New Guinea who were
cannibals of other humans; and add that to the Great Britain meat industry's mistake of feeding vegan cattle the ground
up bodies of sheep and other dead cows which resulted in BSE to understand that the human brain can not be exposed
to any amount of brain tissue or Central Nervous System nerve tissue as Prion Protein Infection Disease is a risk.

There is no such thing as eating bacon, hamburger, baloney, ribs or steak and not ingesting minute amounts of
mammalian animal brain or nerve tissue!!!

The human brain dementia diseases of Alzheimer's Disease (AD) which includes placque development and
Parkington's Disease (PD) have proliferated from being almost unknown 30 years ago to being in the top 10 killers of
Americans and main sources of dementia which fill the nursing homes in America. Their proliferation is associated with
the increased animal mammalian meat per capita ingestion by Americans via the modern fast food high fat and protein
diet. AD and PD are simply lower level intensity Prion Protein Infectious Diseases. They too will lead to death of the
patient. However, they are stoppable and even reversible if the remedial regimen is begun and carried out properly.

III. The Reversible Dementia Diet and Cleansing Regimen

Immediately begin a TOTAL vegan diet a vegetarian diet will not yield a reversal result any lapses
here will not bring fruitful results do you allow babies to eat poison?

1.) For breakfast 2 cups minimal of Mexican Papaya for breakfast fresh cut up or in smoothies with other fresh berries
especially blueberries using evaporated sugar if desired.

2.) For lunch 2 cups minimal unroasted sprouted sunflower seeds and pumpkin seeds with pecans and/or walnuts in
"seed drinks" with evaporated sugar. "Seed drink" directions are in Original Prevention of Sickness Pamphlet
(Pamphlet) freely downloadable from http://www.theuniversityofgod.org/Page8.html.

3.) follow Dr. Dean Ornin, MD.'s Cardiovascular Disease Reversal Diet in his book The Spectrum.

4.) follow the Mediterranean Diet by a.) cutting out fish, sea animals and dairy substituting "mock meat", whole grains,
legumes, seeds and nuts and seed/nut milk and cheeses; and b.) cutting out wine and substituting plenty of freshly
squeezed vegetable juices especially “organic (Whole Food ‘365 Brand)” carrot, spinach, beet, celery and garlic
and fruit juices especially seeded grape and blueberry juice mixed with Mexican Papaya as a smoothie.

5.) use any other vegan diet menus or create entrees by substituting the "mock meats" for animal meat in menus.

6.) each month preferably in the beginning of the month do a 9 day fast on Mexican Papaya you do it along
with dementia patient each day doing a “seed drink” just before bed and a high enema the instructions in Pamphlet.

7.) Prepare daily 12 ounce drink of Southern Mexico Yam Tea made by the Infusion method instructions in Pamphlet.

8.) optionally monthly series of colonics administered by a certified Physical Therapist or Colonic Specialist.

It takes years for AD and PD and the more severe Prion Protein Infection Diseases to manifest symptoms so give
this regimen at least 9 months to show reversal signs.
Gws 5/06/2010
APPENDIXE G.

Jay M. Hoffman, PhD.’s Hunza: 15 Secrets of World's Healthiest and Oldest Living People, 1985 synopsis
Hunza: 15 Secrets of the World’s Healthiest and Oldest People, By Dr. Jay M. Hoffman

1. Biological Horticultural Gardens


and Orchards _________________ Chapter 20: Fantastic Irrigation & Trenches
Mineral Rich Glacial Water Irrigated

2. Healthy Natural Humus Top Soil __ Chapter 21: Soil and Health

3. Peaceful Home Environment _____ Chapter 22: Relaxation in Hunza

4. Clean Air & Deep Breathing ______ Chapter 23: Climate and Air in Hunza

5. Natural Exercise:
Walking and Gardening__________Chapter 24: Exercise the Natural Way

6. Plenty of Sleep _________________ Chapter 25: Sunset to Sunrise Sleep

7. Plenty of Pure Water ____________ Chapter 26: Drinking Habits

8. Rock Resin Tea ________________ Chapter 27: Rock Resin Tea

9. Stress Less Living ______________ Chapter 28: Free From Worry

10. Mineral Rich Foods _____________ Chapter 29: Nutritious Foods

11 a. No Refined, Simple
Carbohydrates _________________ Chapter 30: No Empty Calories in Hunza
No White Sugar, Flours and Rice
Instead Use Whole, Complex and
Unadulterated Carbohydrates

11 b. No Alcohol Drinks _______________Chapter 30: No Empty Calories in Hunza

11 c. No Caffeine Foods or Drinks ______ Chapter 30: No Empty Calories in Hunza


No Chocolate Foods or Drinks
No Coffee and Caffeine Tea
No Caffeine Soda Pops
No Caffeine Energy Supplements

12. Low Fat Diet


No Oils, Fat or Grease ____________Chapter 31: The Low Fat Diet in Hunza

13. Daily Bowel Movements


1 to 4 BM’s per day _____________ Chapter 32: No Constipation in Hunza

14. Vegetarian Diet _________________ Chapter 33: The Hunza Diet


No Animal Flesh or Dairy Foods

15. No Spices and Condiments _______ Chapter 34: No Degenerative Diseases in


No Salt, Pepper, Vinegar and other
Irritating Condiments and Spices
APPENDIXE H-1.

George W. Singleton, HD “Avoid the White Foods” extract from Original Prevention of Sickness:
General Nutrition Instructions (OPS), 1997, rev. 2005
THE ORIGINAL PREVENTION
OF SICKNESS: GENERAL
NUTRITIONAL HERBOLOGY
INSTRUCTIONS

• PREVENTIVE SICKNESS HYGIENE & NUTRITION

• STOMACH AND INTESTINAL CLEANSING

• RELIEF OF CONSTIPATION

• PREVENTION OF CANCER

• PREVENTION OF NUTRITIONALLY RELATED DISEASES

BRCA/SYNERGISTIC RESEARCH AND DEVELOPMENT, INC.

GEORGE W. SINGLETON III


B.A. - General Biology
HD. - Doctor of Herbology
317-293-1519

2005 edition ©
1.
THE ORIGINAL PREVENTION OF SICKNESS: GENERAL NUTRITIONAL INSTRUCTIONS

I. AVOID THE 5 “WHITE FOODS”

a. White Flour/Bread
- substitute 100% whole wheat and other whole grain flours and bread

- without preservatives and without enriched white flour

- “flourless” (sprouting transforms starch to sugar) whole grain breads are best

b. White Rice
- substitute Brown Rice, Wild Rice or Basmati Rice, rinse and soak
overnight or at least 20 minutes

- baking is best

c. White Salt (VIP)


- substitute the “real” rock salt or sea salt and ideally use ground kelp

- “normal” table salt like “Morton’s” is really a by-product from the refining of
bauxite to aluminum which is sprayed on rock salt so it pours

- aluminized salt causes high blood pressure and suspiciously aluminum


shows up in Alzheimer Syndrome victims’ brains and should be avoided

d. White Sugar
- substitute dehydrated “organic” sugar, 100% “organic” maple syrup,
unsulphured black molasses, “organic” honey (moderately)

- avoid white sugar (sucrose), brown sugar, turbinado sugar, fructose produce
acid blood condition from 100% white sugar blood stream absorption

- imitation sugars are carcinogenic

e. White Milk and Dairy


- getting “rennetless” (without the inner cells of the cow’s milk sack)
milk and cheese thereof without hormones is nearly impossible the
vegetarians eating dairy are at risk of TB, polio & “mad cow” disease

- substitute the original dairy from plants ___ soy, rice, nut and inexpensive
seed milks and cheeses

See Section XII for instructions on making seed/nut milk in your blender

NOTE: With the exception of white milk which naturally comes from seeds and nuts, we are
the “victims” of eating unknowingly racist created refined “white colored” foods.”
instead of their natural unrefined ”brown colored” original food counterparts.
7.
THE ORIGINAL PREVENTION OF SICKNESS: GENERAL NUTRITIONAL INSTRUCTIONS

XII. INSTRUCTIONS ON MAKING SPROUTED SEED/NUT MILKS AND DRINKS

This recipe will result in a seed/nut “milk” substitute for cow’s milk or a complete and
easily digested liquid meal seed/nut “drink” with all the nutrients needed for a complete
day’s activities ideal for a vegan or vegetarian on the go and concerned about getting
proper nutrition.

Ingredients: ½ cup raw hulled “organic” sunflower seeds

¼ cup raw hulled “organic” pumpkin seeds

¼ cup raw unhulled “organic” sesame seeds

¼ cup “organic” dehydrated sugar or 100% Grade A Maple syrup

4 cups of filtered, spring or distilled water (do not use tap


water as the chlorine gas used to decontaminate it is
carcinogenic)

Instructions: 1.) put seeds in Blender and cover with 1 cup of the water
and put lid on and let sit at least 12 hours as the seeds will
sprout turning their starch to digestible sugar;

2.) drain and then rinse with 1 cup of the water;

3.) drain and add the final 2 cups of water and the dehydrated
sugar or Maple syrup and blend until liquefied.

4.) Enjoy as a Seed/Nut Milk ___ strain solid material out and drink or use
in recipes as you would cow’s milk.

5.) Enjoy as a Seed/Nut Drink __ drink without starining for a complete


liquid meal.

NOTE: You can substitute other seeds and nuts in place of the
Pumpkin seeds and sesame seeds, but the sunflower
seeds are necessary for they are a complete and easily digestible
food that everyone should eat every day.
APPENDIXE H-2.

George W. Singleton, HD. “The 12 Causes and Prevention of Cancer” extract from OPS, 1997, rev. 2005
THE ORIGINAL PREVENTION
OF SICKNESS: GENERAL
NUTRITIONAL HERBOLOGY
INSTRUCTIONS

• PREVENTIVE SICKNESS HYGIENE & NUTRITION

• STOMACH AND INTESTINAL CLEANSING

• RELIEF OF CONSTIPATION

• PREVENTION OF CANCER

• PREVENTION OF NUTRITIONALLY RELATED DISEASES

BRCA/SYNERGISTIC RESEARCH AND DEVELOPMENT, INC.

GEORGE W. SINGLETON III


B.A. - General Biology
HD. - Doctor of Herbology
317-293-1519

2005 edition ©
11.
THE ORIGINAL PREVENTION OF SICKNESS: GENERAL NUTRITIONAL INSTRUCTIONS

XIV. THE 12 CAUSES OF CANCER AND HOW TO PREVENT IT

This message is dedicated to my Mother and Step Father who have been staunch supporters of
my work over the years and both suffered from cancer. I am reminded I have been warning my
family and friends for 30 years now what I had learned in my medical pathology and "nutritional
herbology" studies starting with my pre-med undergraduate education at the University of
Chicago from 1966 to 1970 (BA in General Biology) and culminating in my Doctor of Herbology
(HD) Degree in 1986 ___ that 50% of the American people will contract preventable cancer. Of
course not having an MD degree and warning so early in the “cancer pandemic” very few have
listened to me seriously.

In addition to my Mother and Step Father contracting cancer, my mother's brother and sister
died of cancer within 6 months of diagnosis in 1998, my Step Father's sister died of cancer in
2002 and his brother died from cancer in 2003. A score of other people in my family and network
have it or have died of it. Several years ago I heard a frustrated and frightened Reverend Jessie
Jackson on his CNN cable show ask desperately what was the cause of the cancer epidemic in
America?

Here is a list of the 12 leading causes of the cancer epidemic known 30 years ago remembering
that cancer cells are one's own cells who mutate and decide to break the "body plan" and revolt
growing on their "own plan" and satisfying their own needs without regard to the body's needs,
overall safety and well being:

#1.) animal organ and flesh foods __ animal protein digestion unlike plant protein
digestion leads directly to the heavy production of the carcinogen uric acid, unnatural animal
manure containing bacteria and fungi which is allowed into the meat from the dead animal's
intestinal tract during the "curing process" of hanging butchered meat caucuses to tenderize the
meat, and these microbes excrete carcinogens (mycotoxins) into the ingester's body; and leads
to ingesting agri-chemicals from the grains these farm animals are fed ___ creates the cancer
cell producing environment of a thick acid pH blood condition with a low level of oxygen;

NOTE: a.) The human body in its normal cellular death maintenance metabolism produces uric
acid that is excreted by the kidneys, and is additionally overloaded from the unnatural addition of
animal organ and flesh foods adding additional uric acid for the body to eliminate.

b.) Dairy products that are rennetless are alright to eat and prevent cancer but are
extremely hard to get. Thus substituting and switching completely to dairyless cheeses (soy) and
soy; and other seed and nut milks is ideal. Refer to Section I above.

c.) Please study Appendix H for the shocking discovery announced in May 2002 on
in Science Magazine that the cause of Colon Cancer has been identified as Lithocholic Acid
which means it is a factor in all cancers being made by the Liver in fatty animal flesh digestion
and stored in the fat tissues by the Liver throughout the body.
12.
THE ORIGINAL PREVENTION OF SICKNESS: GENERAL NUTRITIONAL INSTRUCTIONS

XIV. THE 12 CAUSES OF CANCER AND HOW TO PREVENT IT (continued)

#2.) improper internal hygiene __ people are taught to brush, and floss their teeth
and antiseptically wash their mouth; i.e. the beginning of the digestive/alimentary tract but have
not been told and in fact are encouraged not to conduct enemas thus washing the tail end
segment of their digestive/alimentary tract the colon; the colon being the part of the
intestinal tract that not only withdraws water from the feces but helps purify the blood
along with the kidneys by filtering sold wastes from the blood stream into the large
intestine for elimination in the stools ___ thus leading to a further compounding of the
Cancer Epidemic cause #1 problem above by causing a build up old undigested putrefactive
acid forming mucus waste material amounting to a dangerous anaerobic (oxygen deficient)
cesspool environment teaming with microbes and their carcinogenic toxic excretments;

NOTE: Colon and stomach cancers are the top 2 killing cancers and obviously
are connected to what we eat and drink and the relative internal hygiene of these two key food
digestive organs.

#3.) parasitic tape worms, flukes, protozoa, viruses, bacteria and fungi ___
usually animal manure, organs and flesh food originated but also in contaminated and spoiled
vegetable, fruit, nuts, legumes and grains as well as in the air from other infected people and
animals ___ tapeworms, flukes and protozoa getting the nutrients before the host, viruses
entering cells and mutating their genetic (DNA and or RNA) material carcinogenic, and bacteria
and fungi feeding on undigested food residues ___ with them all excreting carcinogenic wastes
into the core of the body carried every heart beat by the blood stream throughout the body;

#4.) conventionally grown vegetables, fruits and grains contaminated with agri-
chemicals from artificial fertilizers, pesticides, herbicides, growth hormones and fungicides;

#5.) refined, adulterated and preserved foods ___ from farm and garden humus
topsoil erosion and failure to soil remineralize producing especially since World War II and the
onset of chemical agriculture empty caloried food products devoid of biogenic energy and
natural micro-nutrients needed to detoxify carcinogenic wastes and chemicals and fight cancer
cells abound ___ producing in the general population a "subclinical malnutrition" devoid of the
natural fresh fruit, vegetable, nut, seed and grain cancer fighting cytosomes, vitamins,
minerals and enzymes; with additionally chemical preservatives, artificial colors and additives
including propyl alcohol;

#6.) improper beverages and damaged disinfected drinking water ___ alcoholic
beverages including wines and beers overwork the cancer fighting organ the liver while
stimulating briefly increased blood flow by thinning the otherwise average meat eater's thick
acid pH blood condition with a low level of oxygen, as well as the use of the chemical poisons
chlorine gas, fluoride, calcium carbonate and aluminum to name a few to disinfect and treat
sewer utilized water to produce public drinking water which is high pressurized in municipal
water systems damaging its molecular structure and oxygenation ability;
13.
THE ORIGINAL PREVENTION OF SICKNESS: GENERAL NUTRITIONAL INSTRUCTIONS

XIV. THE 12 CAUSES OF CANCER AND HOW TO PREVENT IT (continued)

#7.) loss of 50% of the Oxygen in the Air since 1900 ___ by the continued
deforestation of the planet and environmental chemical pollution killing the oxygen producing
trees, water and soil algae and ocean plankton and seaweed__ which alone explains the Ozone
Holes since Ozone (O3) is produced naturally from Oxygen (O2) and if the former is reduced so
will the later be reduce ___ causing the increased need for nutritional anti-oxidant vitamins and
micronutrients;

#8.) ultraviolet light from the sun ___ can mutate cellular genetic material
carcinogenic is normally filtered out by the atmosphere but allowed through the atmospheric
Ozone Holes ultimately caused by the loss of trees and other oxygen producing plants and thus
loss of oxygen in the atmosphere produces skin cancers;

#9.) industrial chemicals in commercial products, manufacturing work sites and


as environmental pollutants in the air, water, earth, food plants and animals;

#10.) natural and man made radiation ___ from substances as natural radon, from
nuclear power plants, radioactive wastes used to produce "irradiated preserved" foods, nuclear
weapon testing and uses thereof ;

#11.) stress at home, work or extracurricular activities ___ usually from a dislike of
one's livelihood or one's interpersonal relationships blocks the bodies daily detoxing of free
radicals, cancer cells and other carcinogenic toxins; and

#12.) Over indulgence in sexual intercourse, prescription & illicit drugs and greed.

Obviously, it is a wiser lifestyle and economically expedient to prevent the onset of cancer in
one's life before it starts or to cure it in its early stages. You can afford to look like an "extremist
health nut" if you can avoid the cancer epidemic, since the majority of America's people are
content in allowing this cancer epidemic to consume them for the sake of progress, too confident
in their health insurance and hoping for a "magic" cure. Even the first stages of a particular
cancer can benefit from an avoidance of the 12 cancer causes no matter what treatment one
chooses to take ___ the conventional legal chemical, surgery and radiation treatments or an
alternative cure.

Finally, there are so-called "genetically associated cancers" but it is maintained here that
avoiding the 12 cancer causes outlined above will prevent even "so-called " hereditary cancers"
from manifesting which comprise only 5% of all cancer incidents.
14.
THE ORIGINAL PREVENTION OF SICKNESS: GENERAL NUTRITIONAL INSTRUCTIONS

XIV. THE 12 CAUSES OF CANCER AND HOW TO PREVENT IT (continued)

For those needing guidance as to how to deal with Cancer Causes #1, 2 and 3:

1.) the vegan/vegetarian diet is highly recommended for you immediately;

2.) with corresponding "high enemas" every 4 days for at least a year reduced to once a month
there after when all one's sickness symptoms have disappeared targeting the "unseen"
intestinal tract unsanitary mucus food wastes;

3.) please refer to this Original Prevention of Disease: General Nutritional Instructions
Pamphlet which we encourage you to copy and spread through your network for free for
diet, high enema and ridding oneself of tape worms and internal intestinal mucus filth.

For those needing guidance as to how to deal with Cancer Causes #4, 5, 6 and 7:

1.) invest in your health and start buying "organic" food produce and food products from your
local natural food store, market or farmers' market;

2.) invest and plant your own deep bed garden that will produce 4 times as much food with half
the water ___ for faxed deep bed installation instructions call 317-251-0414;

3.) invest and increase the number of oxygen producing landscape trees and ornamental
plants inside and outside your residence;

4.) invest in a Champion quality triturating juicer and prepare your own fresh vegetable and
fruit juices which are rich in oxygen;

5.) avoid drinking tap or well water directly and wasting money on bottled water not in
polycarbonate plastic as any other plastic bottle will leach plastic polymers into the water, and
invest in a mobile Nikken PiMag (Fliptop or Sport) Water Bottle on sale this month at half price
($29 or 4 pack for $88) and Magna Tote ($95) or stationary residential faucet installed Nikken
PiMag Water System ( $850) and purify and naturally energize your potable tap, well or camp
site water to oxygen rich, pH balanced PiMag.

Please feel free to feedback upon this message or ask for specific help with your and any of
your family or network member's situation at 317-251-0414.
APPENDIXE I-1.

Amnesty International USA Citation of American Genocidal Maternal and Infant Mortality Rates, 3/2010
In the United States, women are more likely to die in pregnancy or childbirth than in
40 other countries.
Prevent women from dying in childbirth.

Dear Basheer,

Today we're blowing the lid off the shameful way


that many pregnant women are treated in the United
States.

We've released an unflinching report that details the


disgraceful facts, tragic stories and poor policies
behind maternal death rates among American
women. The results show this country ranks 41st
in the world for risk of dying from pregnancy-
related complications.

It's not just the low ranking that concerns me; it's
that in a country that spends far more on health
care than any other country in the world - and
more on pregnancy and childbirth hospitalization
costs than any other area of medicine - at least half
of these deaths could have been prevented!

Ensure that pregnant women in the United


States get the care that they deserve.

It comes down to a few key areas where a woman's right to a safe childbirth is neglected:

• Women aren't receiving enough information about the signs of complications and the risks of
medical interventions, such as inducing labor or c-sections.
• Unlike in other countries, most women in the U.S. do not receive home visits following
childbirth, even though more than half of all maternal deaths occur within 42 days of giving birth.
• The cost for maternal care is just too high for many women to pay and many women find that
they cannot obtain insurance after becoming pregnant.
• Far too many barriers are preventing pregnant women from getting proper care before, during
and after their delivery.
• African American women are four times as likely to die in pregnancy and childbirth than
white women. Disparities have not improved in more than 20 years.
• Few systems are in place to analyze existing problems and propose possible solutions to
improve maternal health standards.

Here are 2 things we can do right now to combat preventable maternal deaths:

1. Urge the Department of Health and Human Services (HHS) to improve timely access to
quality maternal care. As the principal agency for protecting health in this country, this department
must be at the heart of efforts to change the system. We are asking Kathleen Sebelius, the
Secretary of this department, to work with President Obama in setting up an Office of Maternal
Health within HHS dedicated to providing the much-needed oversight for preventing, recognizing
and responding to the leading complications that cause pregnancy-related deaths.
2. Volunteer to meet with Senators and Representatives in your local district to inform them
about this tragedy. Amnesty supporters will be spreading the word to elected officials March 29 -
April 9th and engaging them to prevent maternal deaths. We will train you and give you the support
you need to educate and enlist your representatives in the effort to reduce maternal deaths.

The more I learn about the women and families whose lives have been affected by this devastating crisis,
the more convinced I am that we must do something about it.

Help us protect women's health. Help us deliver the message that maternal health is a human right.
In Solidarity,

Larry Cox
Executive Director
Amnesty International USA

Kathleen Sebelius 3/23/2010


Secretary
US/Department of Health and Human Services (HHS)
Washington, DC.

Your Honor US/HHS Secretary Katheleen Sebelius:

As the 2007 and 2009 European Union Humanitarian Grantee we are hopeful that the Amnesty International, Inc.
citing the disturbing situation uncovered in 2008 by the Center for Disease Control on the status of the high infant
mortality rates in America compared to international community especially in the inner cities at 14% which is clearly
genocidal will lead to definitive action to eradicate this problem.

Please find attached the Red Paper: Interrogatory of the American Health Care Issue Omission: The Great
Ramifications of Dietary Cholesterol and Bile Acid Metabolism: The Chronic Diseases and Syndromes
delivered already to the White House/Office of Health Care Reform, Office of the First Lady and the Vice President as
well as leaders in the US Congress which on page 4 states:

"2.) US Infant Mortality Rate (IMR) at 6.9% as reported in 2008 by the US Center for Disease
Control and Prevention (CDC) places America 29th in industrialized countries compared
with Japan's IMR of 3.1% and 3 rd amongst industrialized nations. The IMR amongst
African Americans at 16.7% is genocidal!

Note a: The CDC in its 2008 Annual Report on the nation's Infant Mortality Rates
pointed to the lack of progress in infant mortality prevention from 2000 to 2006
__ a lack of progress in this vital health index not seen since the 1960's.
America could once boast about its IMR but has steadily lost its health status
advantage internationally the last 30 years since passage of the Civil Rights Bill.

Note b: This period from 2000 to 2006 coincides with: i.) the proliferation of the high fat and
high protein fast food restaurants in America; ii.) the unannounced substitution of
the federally subsidized production of the higher caloric high fructose corn syrup for
the lower caloric sugar cane and sugar beet sucrose as a sweetener by America's
refined food industry; iii.) an attempt to corrupt medical science further with federal
research using statistical manipulation of death rates to give overweight and obese
individuals’ longer life spans than normal and underweight individuals; iv.) the
appearance of the “Metabolic Syndrome” [the cluster of cardiovascular and
diabetic risk factors including visceral (waist) obesity, high blood pressure, insulin
resistance, elevated triglycerides and low HDL cholesterol]; and the manifestation of
the Metabolic Syndrome as a major dysfunction of the people.

Note c: In a disturbing finding the infant merconum (first bowel movement after birth) as
well as neonatal newly born infant bile and infant blood contains high amounts of 22-
Hydroxy Cholesterol, C-24 mono-hydroxy bile acids called 3-beta-hydroxy cholenoic acid
and Lithocholic acid which are dangerous co-mutagenic, co-carcinogenic, atherogenic and
toxogenic linked to liver cholestasis (gall stone blockage of the gall bladder) and the
Oxysterols (24, 25 and 27 Hydroxycholesterols). In particular Premature babies are
associated with the at risk of high concentration of C-24 monohydroxy bile acids and high
Dietary Cholesterol maternal diets. [F14]

Esoterically as documented above and in Appendix A-1 because the human genome is
encoded as a herbivore/vegan genetically, the human liver of the pre-natal, neonatal and
infant processes any Dietary Cholesterol from the Mother’s shared blood system or
amniotic fluid as a “slow poison” through a “Third Bile Acid Metabolic Pathway” producing

a unique mix of bile acids that persists from conception but is slowly transformed after birth
by the development of intestinal flora until about 4 years of age when the adult pattern of
dietary cholesterol and bile acid metabolism dominates."
Page 2_ US/Department of Health and Human Services (HHS Secretary Kathleen Sebelius

It is very clear from research and development work under great suppression that
unborn babies in the womb are at risk from the immense co-mutagenic, co-carcinogenic,
cholestatic and the toxogenic effects on the liver, heart, brain, kidneys, pancreas of Dietary
Cholesterol and the over 20 of its derivatives inventoried in Table 3 of the Red Paper
especially the mono-hydroxy-bile acids specifically Lithocholic acid and its isomers and 3-
beta 5 Cholenoic acid.

It is clear that now with the passage of the Health Care Reform Legislation that the US/HHS
can lead an innovative infant mortality amelioration implementation that if it included the
following 2 elements would in 24 months show significant lowering of this problem
especially in the nation's inner cities:

a.) recommend that participating doctors and other health practitioners


implement a no dietary cholesterol regimen on women at risk for infant
mortality especially those in America's inner cities; and

b.) encourage the relevant Executive Branch agencies to channel green job
monies into cleaning the urban areas of litter __especially zeroing in on
plastics as their UV light deterioration pollutes the water table and
drinking water with low levels of hydrocarbon mutagens, carcinogins
and cytotoxins that the bile acids and other Table 3 identified
derivatives promote as co-mutants, cocarcinogen and co-toxogens; e.g.
pvc's and other aromatic polycyclic hydrocarbons are found in Mothers'
milk.

As the 2007 EUHG recipient I am available for assisting you in such an endeavor
at no cost.

Sincerely and yours in service,

State of the World Forum Member # 20827


2007 and 2009 European Union Humanitarian Grantee
APPENDIXE I-2.

Global Maternal and Infant Death Rates Decrease while American Rates Genocidally Increase, 4/2010
APPENDIXE I-3.

Glantz, Anna, et al, article “Intrahepatic Cholestasis in Pregnancy: Relationships Between Bile Acid
Levels and Fetal Complication Rates” in Hepatology J, V 40, No. 2,
pp 467-74, 2004
Intrahepatic Cholestasis of Pregnancy: Relationships
Between Bile Acid Levels and Fetal Complication
Rates
Anna Glantz,1 Hanns-Ulrich Marschall,2 and Lars-Åke Mattsson1

Intrahepatic cholestasis of pregnancy (ICP), characterized by pruritus in the second half of


pregnancy, entails an increased risk to the fetus. This study was designed to determine the
incidence and fetal complication rates in ICP, and to define groups at increased risk. In an
prospective cohort study conducted between February 1, 1999, and January 31, 2002, all
45,485 pregnancies in a defined region of Sweden (Västra Götaland) were screened for ICP,
defined as otherwise unexplained pruritus of pregnancy in combination with fasting serum
bile acid levels >10 ␮mol/L. Pruritus was reported by 937 (2.1%) women, and ICP was
diagnosed in 693 (1.5%). Simple logistic regression analyses showed that the probability of
fetal complications (spontaneous preterm deliveries, asphyxial events, and meconium stain-
ing of amniotic fluid, placenta, and membranes) increased by 1%–2% per additional
␮mol/L of serum bile acids. Complementary analyses showed that fetal complications did
not arise until bile acid levels were >40 ␮mol/L. Gallstone disease and a family history of
ICP were significantly (P < .001) more prevalent in the group of ICP patients with higher
bile acid levels. In conclusion, we found an incidence of ICP in our population of 1.5%.
From complication rates recorded prospectively, we could define a mild (81%) and a severe
(19%) form of ICP, the latter with bile acid levels >40 ␮mol/L. No increase in fetal risk was
detected in ICP patients with bile acid levels < 40 ␮mol/L, and we propose that these women
be managed expectantly, which would significantly reduce the costs of medical care.
(HEPATOLOGY 2004;40:467– 474.)

I
ntrahepatic cholestasis of pregnancy (ICP) is a condition complication rates difficult to compare. When, in addition
characterized by pruritus in the second half of preg- to pruritus, clinical jaundice was used to define ICP, higher
nancy. It persists until delivery, after which it ceases fetal complication rates were reported than when diagnosis
promptly. A genetic background is suggested by family clus- was based only on elevated bile acid and transaminase lev-
tering and demographic variations, with the highest inci- els.2,3,6 – 8 The Swedish ICP incidence figure is taken from a
dences reported from Chile-Bolivia (6%–27%) and Sweden study using only pruritus in pregnancy as the inclusion cri-
(1–1.5%).1 ICP is associated with an increased risk of pre- terion, and that study did not report increased fetal risk as-
term delivery in 19%– 60%,2–5 intrapartum fetal distress in sociated with ICP.9
22%– 41%, and intrauterine fetal death (IUFD) in 0.75%– Nowadays, elevation of serum bile acids is considered to
1.6% of the affected pregnancies.3– 6 The diagnostic criteria be the most appropriate laboratory parameter for diagnosis
for ICP have varied over time in different reports, making of the condition.8,10 –12 It is reasonable to believe that ICP
constitutes a continuum, ranging from light to severe forms,
but there has been an absence of algorithms to identify preg-
Abbreviations: ICP, intrahepatic cholestasis of pregnancy; IUFD, intrauterine
fetal death; CTG, cardiotocography.
nancies entailing increased fetal risk. The aims of this pro-
From the 1Department of Obstetrics and Gynaecology, Sahlgrenska University spective cohort study were to determine the incidences of
Hospital/East, Göteborg, Sweden, and 2Karolinska Institutet, Department of Med- pruritus of pregnancy and ICP, and to investigate whether
icine, Huddinge University Hospital, Stockholm, Sweden.
Received January 5, 2004; accepted April 23, 2004.
fetal complication rates correlated to the severity of the dis-
Supported by grants from FOU, Västra Götaland region. ease, measured by bile acid levels in maternal serum.
Address reprint requests to: Anna Glantz, M.D., Dept. of Obstetrics/Gynaecol-
ogy, Sahlgrenska University Hospital/East, 416 85 Göteborg, Sweden. E-mail:
anna.glantz@vgregion.se; fax: ⫹46 31 25 43 87. Patients and Methods
Copyright © 2004 by the American Association for the Study of Liver Diseases.
Published online in Wiley InterScience (www.interscience.wiley.com). The incidences of pruritus in pregnancy and ICP were
DOI 10.1002/hep.20336 studied prospectively in the Västra Götaland region of
467
468 GLANTZ, MARSCHALL, AND MATTSSON HEPATOLOGY, August 2004

Sweden between February 1, 1999, and January 31,


2002. The area had 1,500,462 inhabitants in February,
2001, and all women with pregnancies leading to delivery
in the region during the study period were screened for
ICP.
In Sweden, all normal pregnancies are monitored by
midwives at local antenatal clinics. If pregnancy compli-
cations occur, the women are referred to an obstetrician at
the nearest department of obstetrics. All 106 local ante-
natal clinics and the 6 departments of obstetrics with de-
livery wards in the region participated in the study.
Pruritus in pregnancy without any obvious dermato-
logical explanation was the inclusion criterion. Women
were consecutively included in the study. Verbal and writ-
ten informed consent was obtained from all participants.
Each participant received a study protocol and was
instructed to bring it to every appointment during preg-
nancy, including the stay at the delivery ward. A medical
history, including heredity for pruritus in pregnancy, out-
come of prior pregnancies, skin disorders, atopic and al-
lergic conditions, liver/gallbladder disorders, and other
relevant illnesses, was taken. At weekly visits until partu-
Fig. 1. Total number of deliveries in women with pruritus of pregnancy
rition, a fasting blood sample for analysis of total bile acids in a defined area. Women in the observational study were categorized
was drawn from an antecubital vein, and the patient was according to bile acid levels in serum.
instructed to estimate her pruritus on a 100-mm-long
visual analogue scale with the endpoints “no pruritus at
all” (0 mm) and “worst possible pruritus” (100 mm). If Participants who did not attend the weekly visits or
the total bile acid levels were normal (⬍10 ␮mol/L), the who did not return their study protocol to the delivery
patient was scheduled for checkups at the local antenatal ward were considered as “lost to follow-up.” Of the 937
clinic. If the total bile acid level was ⱖ10 ␮mol/L at any women registered, 820 women completed the study, and
time, the patient was referred to the nearest department of 117 were lost to follow-up (12.5%). Data from these
obstetrics for further care. The study protocol instructed women were included in the calculation of the incidences
the managing obstetricians to take fasting blood samples of pruritus in pregnancy and ICP but were excluded from
for analysis of bile acids, aminotransferases, and bilirubin the analyses of patient history and outcome of the present
in serum once a week until delivery, to ask the patients to pregnancy (Fig. 1).
estimate their pruritus on a visual analogue scale, and to All women with ICP at a gestational age less than 37
monitor fetal well-being by cardiotocography (CTG) at weeks were invited to participate in a double-blind, pla-
the same appointments. No other specific instructions cebo-controlled intervention study comparing treatment
were given to the obstetricians regarding how to manage effects of dexamethasone and ursodeoxycholic acid. Data
the pregnancies or whether to time the deliveries. Data from the 130 women enrolled were analyzed regarding
recorded at delivery included gestational age, mode of incidence of pruritus and ICP, and patient history, but
delivery, spontaneous or induced labor, blood loss, fre- they were not included in the calculations concerning the
quency of asphyxial events (operative delivery due to as- outcome of the present pregnancy.
phyxia; Apgar score ⬍7 at 5 minutes; postpartum pH Total serum bile acids were analysed with an enzy-
⬍7.05 in umbilical arterial blood), and meconium stain- matic, colorimetric method (Enzabile, Biostat Diagnostic
ing of amniotic fluid or green staining of placenta and Systems, Stockport, UK). Aminotransferases were ana-
membranes, indicating a longer period since meconium lyzed with standard laboratory methods.
passage. All data concerning patient history, laboratory The study protocol was conformed to the ethical
results, and estimation of pruritus on the visual analogue guidelines of the Helsinki Declaration, and the study
scale as well as delivery data were recorded in the study was approved by the Swedish Medical Products Agency
protocol. and the local Ethics Committee of the Faculty of Med-
HEPATOLOGY, Vol. 40, No. 2, 2004 GLANTZ, MARSCHALL, AND MATTSSON 469

icine at the University of Göteborg, Göteborg, Swe-


den.
Statistical Analyses and Stratification. In a first
step, the relationship between serum bile acid levels and
fetal complications was analyzed with logistic regression
analyses. In the next step, logistic regression was com-
bined with spline functions. This approach resulted in
smooth curves with a higher degree of freedom, allowing
a piecewise analysis of subintervals in the curves. It was
thus possible to estimate the relationship between serum
bile acid levels and fetal risk in each subinterval. This Fig. 2. Frequencies of pruritus, preterm deliveries and IUFD in previ-
approach allowed stratification of the patient material ous pregnancies categorized according to severity of ICP in the present
into three groups: “no ICP” (bile acid levels ⬍10 ␮mol/ pregnancy. White bar indicates no ICP (serum bile acids ⬍ 10 ␮mol/L);
gray bar indicates mild ICP (bile acids 10 –39 ␮mol/L); and black bar
L), “mild ICP” (maximum bile acid levels of 10-39 indicates severe ICP (bile acids ⱖ 40 ␮mol/L).
␮mol), and “severe ICP”(bile acid levels ⱖ40 ␮mol/L at
any time) (Fig. 1). The stratified groups were used when
data regarding the patient’s history was analysed and for Of these, 365 were nulliparas, 280 were primiparas,
presentation of fetal complication rates. Differences be- and 175 were multiparas. The parous women (n ⫽ 455)
tween groups were calculated according to the chi-square had a total of 684 pregnancies leading to delivery in their
method. P-values ⬍.05 were considered to be statistically histories. The frequencies of pruritus, preterm deliveries,
significant. and IUFD in previous pregnancies varied, as shown in
Correlation between bile acid and alanine transami- Figure 2. Four percent of the no ICP group had a history
nase levels was estimated using Pearson’s correlation test. of preterm delivery, compared to 25% of the severe ICP
Correlation between bile acid levels and pruritus was cal- group (P ⬍ .001). IUFD had occurred in 1 previous
culated using Kendall’s ␶_b. pregnancy in the no ICP group (0.6%) and had not been
associated with pruritus of pregnancy. However, a history
Results of previous IUFD was found in 4.1% of women in the
severe ICP group (P ⬍ .001). In this group, all prior cases
All 45,485 pregnancies leading to delivery in the region of IUFD had been associated with pruritus of pregnancy.
during the study period were screened for ICP. A total of The prevalence of gallstone disease (defined as prior
937 women, comprising 2.1% of the pregnant popula- cholecystectomy or ultrasound-verified gallstones) and
tion, complained of pruritus in pregnancy and were in- heredity for pruritus of pregnancy also varied among the
cluded in the study. ICP, defined as pruritus in pregnancy groups. Gallstone disease was reported by 24 women
in combination with serum bile acids ⱖ10 ␮mol/L, was (2.9%). The prevalence in the different groups were: no
found in 693 women (1.5%). The distribution of maxi- ICP 0.5%, mild ICP 2.3%, and severe ICP 7.4%, respec-
mum bile acids during pregnancy is illustrated in Fig- tively (no ICP vs. severe ICP, P ⬍ .001). Heredity for
ure 1. pruritus of pregnancy was reported by 173 women
The 117 women lost to follow-up stated that sponta- (21%), of which 13% did not have ICP, 21% had mild
neous relief of pruritus (n ⫽ 45), discomfort from re- ICP, and 30% had severe ICP (no ICP vs. severe ICP, P ⬍
peated venous punctures (n ⫽ 18), or the long distance .001).
between home and hospital (n ⫽ 11) were major reasons Previous allergic reactions with skin manifestations
for discontinuation. Thirty-eight women did not explain had occurred in a total of 25% and did not vary among
why they stopped attending, and 5 women moved to the groups. The total frequency of other atopic conditions
another region of Sweden. Some patients lost to follow-up such as asthma and eczema was 8.8%, but a variation
were tested for total bile acids only once, while others were among the groups was noticed. In the no ICP group, 15%
tested as many as 8 times. Of the women lost to follow-up, of the patients reported atopy, while 8% in the mild ICP
58 had bile acid levels ⬍10 ␮mol/L, and 59 had bile acid group and 3% in the severe ICP group had this condition
levels 10 –29 ␮mol/L. (no ICP vs. severe ICP, P ⬍ .001). The frequency of
psoriasis was 1.2%, with no difference among the groups.
Patient History A total of 733 women were ever-users of oral contra-
Medical histories were taken from all 820 women who ceptives, of which 14 women (1.7%) had experienced
completed the study (Fig. 1). pruritus during use.
470 GLANTZ, MARSCHALL, AND MATTSSON HEPATOLOGY, August 2004

Table 1. Bile Acid Level-Correlated Probability of Fetal Complications


Odds Ratio*
Variable ␤ SE (95% CI) P Value

Preterm delivery Constant ⫺3.7836 0.2631


Bile acids 0.0209 0.0041 1.02 (1.01–1.03) ⬍.001
Asphyxial events Constant ⫺2.8940 0.1916
Bile acids 0.0117 0.0037 1.01 (1.00–1.02) .0016
Meconium passage Constant ⫺1.5962 0.1245
Bile acids 0.0159 0.0032 1.02 (1.01–1.02) ⬍.001
Green staining of placenta/membranes Constant ⫺2.4675 0.1612
Bile acids 0.0148 0.0034 1.01 (1.01–1.02) ⬍.001

*The odds ratio corresponds to the comparisons of risk between two levels of bile acids, where the second value is one unit (␮mol/L) higher than the first. The odds
ratio 1.02 states that the risk of an event increases by 2% for each additional unit of bile acid.

Present Pregnancy nium staining of amniotic fluid, placenta, and mem-


Data concerning the present pregnancy were collected branes, P ⬍ 0.001; asphyxial events, P ⬍ .01).
from the 690 women completing the observational study The total prematurity rate was 11.7%, including pre-
(Fig. 1). term birth in multiple pregnancies and iatrogenic prema-
Fetal Complications. The frequency of spontaneous, ture deliveries due to the severity of complications or
preterm birth in singleton pregnancies was 4.3%, and symptoms. The total prematurity rate was higher in the
asphyxial events occurred in 7.1%. Meconium staining of severe ICP group (P ⬍ .001) than in the other groups.
amniotic fluid was noted in 24.8% of the deliveries, and The total planned delivery rate in term pregnancies was
green staining of placenta and/or membranes was ob- 25%, of which 18% were planned inductions of labor and
served in 12.2%. 7% were elective cesarean sections. The planned delivery
A correlation was found between bile acid levels and rate in term pregnancies was 21% in the no ICP group,
fetal complication rates. Analysis with simple logistic re- 24% in the mild ICP group, and 32% in the severe ICP
gression showed that the probability of preterm delivery, group (Fig. 5).
asphyxial events, meconium staining of amniotic fluid, IUFDs. Three IUFDs occurred during the observa-
and green-staining of placenta and membranes increased tion period (3/690, or 0.4%). One was a singleton preg-
by 1%–2% for each additional ␮mol/L of bile acid. Anal- nancy with onset of pruritus in the 34th week of gestation.
ysis by a combination of spline functions and logistic Bile acids were 94 ␮mol/L at inclusion in the 36th week,
regression revealed that the probability of preterm deliv- and IUFD was discovered when labor started spontane-
ery, asphyxial events, and green staining of placenta and ously a few days later. The second IUFD occurred in a
membranes did not increase until bile acid levels exceeded twin pregnancy, with onset of pruritus in the 24th week of
40 ␮mol/L, while the probability of meconium staining gestation. At inclusion in the 25th week of gestation, bile
of amniotic fluid started to rise when bile acid levels ex- acids were 130 ␮mol/L. At the next checkup, 4 days later,
ceeded 20 ␮mol/L (Table 1 and Fig. 3A-D ). 1 twin was dead, and the patient spontaneously gave birth
The relationship between fetal complication rates and to a vital albeit premature baby in the 28th week of ges-
bile acid levels could also be demonstrated by analyzing tation. The third case was also a twin pregnancy, with
the differences in complication rates among the stratified onset of pruritus in the 36th week of gestation. Bile acids
groups, as demonstrated in Figure 4 . Spontaneous pre- were 27 ␮mol/L. At a routine checkup a few days later,
term delivery occurred in 2.7% of the no ICP group and the second twin was found to be dead. Spontaneous onset
in 2.2% of the mild ICP group, and the corresponding of labor started in the 39th week of gestation, but the
figure was 16.7% in the severe ICP group. Asphyxial patient was delivered by an acute cesarean section. A tight
events occurred in 5.4% of the no ICP group, 6.3% of the knot on the umbilical cord of the dead twin was found,
mild ICP group, and 13.5% of the severe ICP group. The while the other twin was healthy.
occurrence of meconium staining of amniotic fluid was CTG. CTG-surveillance of the fetuses was performed
21% in the no ICP group, compared to 44% in the severe on 1,479 occasions at scheduled checkups before onset of
ICP group. Green staining of placenta and membranes labor. In 52 cases, the CTG registration was assessed as
also differed among the no ICP group (8%), the mild ICP pathological and required prolonged or repeated registra-
group (11%), and the severe ICP group (25%). The rates tions. In all but 2 cases, the CTG registrations normalized
of all complications differed between the severe ICP spontaneously. These 2 patients were referred to the de-
group and the other groups (preterm delivery, and meco- livery ward for induction of labor and gave birth vaginally
HEPATOLOGY, Vol. 40, No. 2, 2004 GLANTZ, MARSCHALL, AND MATTSSON 471

Fig. 3. Probability of (A) preterm deliveries, (B) asphyxial events, (C) meconium staining of amniotic fluid, and (D) green staining of placenta and
membranes in relation to serum bile acid levels (␮mol/L) analyzed with simple logistic regression (thick line) and spline functions (medium line),
the latter with 95% CI (thin line).

to healthy infants without asphyxial events. No CTG ab- pregnancy in this study was 1/63 pregnancies, compared
normalities requiring immediate operative delivery were to an expected frequency of 1/130 –1/300.13,14
recorded.
Age, Parity, Onset of Pruritus and Blood Loss. Discussion
There was no difference among the stratified groups re-
garding age and parity. The median gestational age at In this prospective study, more than 45,000 pregnant
onset of pruritus was in the 31st week. A trend, not reach- women were screened for ICP, and the incidence of fetal
ing statistical significance, toward later onset of pruritus complications in these pregnancies was investigated. The
in more severe ICP forms was recorded (no ICP, 27th data were comprehensively collected, according to Swed-
week of gestation; mild ICP, 31st week of gestation; and ish health care system routines.
severe ICP, 33rd week of gestation, respectively). Esti- In our experience, women with severe pruritus in
mated blood loss in vaginal deliveries did not differ pregnancy seek help and are willing to cooperate to
among the groups (median, 400 mL for all groups; mean, attain relief of symptoms. It is therefore unlikely that
423– 484 mL). there were many nonparticipating women with pruri-
Correlation Coefficients, Twin Pregnancies, and tus and elevated bile acid levels during the study pe-
Pruritic Urticarial Papules and Plaques of Preg- riod. We therefore believe that the patient material in
nancy. No patient presented with clinical jaundice. The this study is representative of a pregnant population in
correlation coefficient between serum bile acids and esti- Sweden.
mated intensity of pruritus on a visual analogue scale was Pruritus occurred in 2.1% of the pregnancies. Among
0.108 (P ⬍ .01). The correlation coefficient between bile these cases, ICP was diagnosed when fasting serum bile
acids and alanine aminotransferase was 0.349 (P ⬍ .01). acid levels were ⱖ10 ␮mol/L, as was the case in 1.5% of
There were 38 twin pregnancies in the observational the pregnancies, in concordance with a previous Swedish
study, comprising 5.5% of the pregnancies. Pruritic urti- study.9 In contrast to that study, which did not include
carial papules and plaques of pregnancy was diagnosed by bile acids as a diagnostic criterion, we found an increased
a dermatologist in 11 cases, of which 10 also had ICP. The fetal risk associated with ICP and, more importantly, a
frequency of pruritic urticarial papules and plaques of bile acid level distinguishing 2 degrees of risk.
472 GLANTZ, MARSCHALL, AND MATTSSON HEPATOLOGY, August 2004

(P ⬍ .01). This observation might indicate an association


between severity of the disease and IUFD.
The incidence of intrapartal meconium staining of am-
niotic fluid varies between 17% and 24 % in a normal
pregnant population16 and is considered as a warning sig-
nal of possible fetal distress. It is, however, also known
from animal models that high maternal bile acid levels
stimulate fetal colonic motility, causing the fetus to void
meconium.17 In our material, the probability of meco-
nium passage and green staining of placenta and mem-
branes increased gradually in relation to elevated bile acid
Fig. 4. Fetal complication rates in pregnant women with ICP. White
bar indicates no ICP; gray bar indicates mild ICP; and black bar
levels in an almost linear fashion, calculated with simple
indicates severe ICP. logistic regression. In the stratified groups, the frequencies
of meconium passage were 21% in the no ICP group and
22% in the mild ICP group, suggesting that ICP with bile
acid levels below 40 ␮mol/L does not affect the colonic
There was an overall positive correlation between fetal motility of the fetus. These findings were in contrast to
complication rates in ICP patients and the level of total those of the severe ICP group, in which meconium pas-
bile acids in maternal serum. Logistic regression analyses sage was observed in 44%.
demonstrated that the probability of fetal complications The mechanisms of preterm delivery in ICP are still
such as spontaneous preterm deliveries, asphyxial events, unclear, but they have been discussed in light of in vitro
and meconium staining of amniotic fluid, placenta and findings indicating that myometrial cell preparations
membranes increased by 1%–2% for each additional from ICP women show a more intense response to oxy-
␮mol/L of bile acid. However, use of the refined tech- tocin stimuli than do cells from healthy women.18 A re-
nique of spline functions revealed that the probability of cent article describes that myometrial strips from healthy
these events did not increase until bile acid levels exceeded women show an increased response to oxytocin and an
40 ␮mol/L. Up to this level the incidence of fetal compli- increased oxytocin-receptor expression after being incu-
cations in ICP patients did not differ significantly from bated with cholic acid.19
that in a normal pregnancy. A majority of the women Family clustering and a large demographic variation,
with ICP (81%) had serum bile acids between 10 and 39 with the highest incidence figures of ICP reported from
␮mol/L without increased rate of fetal complications, Chile-Bolivia and Scandinavia, support the hypothesis of
whereas 19% were found to have serum bile acids ⱖ40 a substantial hereditary component of the disease, but the
␮mol/L associated with a raised fetal risk. These data molecular genetic background has yet to be determined.1
actually prove for the first time a relationship between the
severity of ICP and fetal complications. That low levels of
serum bile acids confer minimal fetal risk is also clinically
important.
ICP has been reported to be associated to an increased
risk of IUFD.3– 6 In this study, a low frequency of IUFD
was recorded (3/690, or 0.4%), similar to rates found in
the normal pregnant population in Sweden.15 We assume
that the low incidence of IUFD was due to increased
attention devoted to ICP and its symptoms during the
study, which might have led to early intervention. This
hypothesis may be substantiated by the high rates of in-
duction of labor and planned cesarean section (25%).
Fig. 5. Timing of spontaneous and planned deliveries in women,
Planned delivery before term in women with ICP has categorized according to severity of ICP. Dark gray bar indicates spon-
been reported to protect against IUFD.2–5 The frequency taneous singleton preterm delivery; striped bar indicates spontaneous
of IUFD in previous pregnancies in the study population twin preterm delivery/preterm induction or preterm cesarean section;
was 1.3%. Interestingly, there was a striking difference medium gray bar indicates planned induction or planned cesarean
section after 37 weeks of gestation; and light gray bar indicates
between IUFD in previous pregnancies reported in the no spontaneous onset of labor after 37 weeks of gestation. The arrows
ICP group (0.6%) and in the severe ICP group (4.1%) indicate the total prematurity rate.
HEPATOLOGY, Vol. 40, No. 2, 2004 GLANTZ, MARSCHALL, AND MATTSSON 473

Our data revealed a correlation between a history of gall- reduce bile acid levels and provide relief from pruritus.
stone disease and the severity of ICP in the present preg- Ursodeoxycholic acid has yielded promising results in a
nancy. In the no ICP group, 0.5% of the women reported small, randomized, placebo-controlled study25 but has
gallstone disease, compared to 7.4% in the severe ICP not been approved for treatment of ICP as yet.
group (P ⬍ .001). A 2-fold increase in the prevalence of In conclusion, pruritus of pregnancy was reported
gallstone disease among women with ICP has previously by 2.1% of pregnant women in western Sweden. The
been reported.20 A recent report stated that genetic factors incidence of ICP, defined as pruritus in pregnancy and
were responsible for at least 30% of symptomatic gall- bile acid levels ⱖ10 ␮mol/L, was 1.5%. The majority
stone disease,21 supporting the hypothesis that ICP and of ICP patients (81%) had a mild form of the condition
gallstone disease might at least to some extent have a com- (bile acids 10 –39 ␮mol/L). These women were ex-
mon, underlying genetic explanation. posed to the same risk of fetal complications as an
Twin pregnancies constituted 5.3% of all pregnancies ordinary obstetrical population, and we therefore pro-
in this study, which is in concordance with previous re- pose that these women be managed expectantly, which
ports indicating a 5-fold increase of ICP in twin pregnan- would significantly reduce the costs of medical care. A
cies, compared to singleton pregnancies.22 severe form of ICP occurred in 19%. With bile acids
In this study, the correlation between bile acid levels ⱖ40 ␮mol/L, these patients suffered a significantly
and alanine aminotransferase was poor. However, a weak higher rate of fetal complications such as asphyxial
correlation between bile acid levels and reported pruritus events, spontaneous preterm deliveries, and meconium
was found, but the subjective symptoms cannot predict staining of amniotic fluid, placenta, and membranes,
severity of the disease in terms of bile acid concentrations. compared to women with normal bile acid levels and
Accordingly, the clinical relevance of alanine aminotrans- women with mild ICP.
ferase for diagnosis and surveillance of ICP is question-
able. Acknowledgment: The authors thank all midwives
Of all pregnant women with pruritus, 26% did not and obstetricians in the Västra Götaland region for pro-
viding and caring for study patients; Thorkild Nielsen,
show any laboratory signs of ICP. This group had an
Elisabeth Almström, Tomas Gredmark, Margareta Hell-
earlier onset of pruritus and reported a significantly gren, and Mona Söderlund for critically reviewing the
higher frequency of atopic diseases (asthma, eczema) study design; study nurse Ann Christiansson, who was of
than the other groups, implying that pruritus might invaluable help in coordinating the study centers; and
have been of dermatological origin in these cases. Anders Odén for professional assistance with the ad-
Atopic dermatitis is more likely to deteriorate than to vanced statistical calculations.
remit in pregnancy.23
In some countries, especially Sweden and Chile-Bo- References
livia, ICP patients constitute a fairly large patient group. 1. Lammert F, Marschall H-U, Glantz A, Matern S. Intrahepatic cholestasis
We suggest that pregnant women with pruritus should be of pregnancy: Molecular pathogenesis, diagnosis and management.
surveilled with repeated determinations of serum bile ac- J Hepatol 2000;33:1012–1021.
2. Bacq Y, Sapey T, Brechot MC, Pierre F, Fignon A, Dubois F. Intrahepatic
ids. Patients could be managed expectantly when bile acid
cholestasis of pregnancy: a French prospective study. HEPATOLOGY 1997;
levels remain below 40 ␮mol/L. Our data do not indicate 26:358 –364.
that this group would benefit from induction of labor 3. Fisk NM, Storey GN. Fetal outcome in obstetric cholestasis. Br J Obstet
before term. Symptomatic treatment, such as H1-receptor Gynaecol 1988;95:1137–1143.
4. Rioseco AJ, Ivankovic MB, Manzur A, Hamed F, Kato SR, Parer JT, et al.
blockers or ursodeoxycholic acid, should be offered to Intrahepatic cholestasis of pregnancy: a retrospective case-control study of
these women.24 Fetuses of ICP patients with higher serum perinatal outcome. Am J Obstet Gynecol 1994;170:890 – 895.
bile acids are exposed to increased risks. CTG was not 5. Alsulyman OM, Ouzounian JG, Ames-Castro M, Goodwin TM. Intrahe-
patic cholestasis of pregnancy: perinatal outcome associated with expectant
proven to be of any value for detection of fetal risk in these
manegement. Am J Obstet Gynecol 1996;175:957–960.
women. 6. Laatikainen T, Tulenheimo A. Maternal serum bile acid levels and fetal
Induction of labor in the 38th week of gestation has distress in cholestasis of pregnancy. Int J Gynaecol Obstet 1984;22:91–94.
previously been shown to reduce fetal risk.4 This study 7. Rencoret R, Aste H. Jaundice during pregnancy. Med J Aust 1973;1:167–
169.
indicated that active management should be restricted to 8. Shaw D, Frolich J, Wittman BA, Willms M. A prospective study of 18
the group with bile acids ⱖ40 ␮mol/L. Since this group patients with cholestasis of pregnancy. Am J Gynecol 1982;142:621– 625.
constitutes only 19% of the ICP population, the costs of 9. Berg B, Helm G, Petherson L, Tryding N. Cholestasis of pregnancy. Acta
Obstet Gynecol Scand 1986;65:107–113.
medical care could hereby be reduced significantly. If ges-
10. Fisk N, Bye WB, Storey B. Maternal features of obstetric cholestasis: 20
tational age does not permit induction of labor, it seems years experience at King George V Hospital. Aust N Z J Obstet Gynaecol
reasonable to administer pharmacological treatment to 1988;28:172–176.
474 GLANTZ, MARSCHALL, AND MATTSSON HEPATOLOGY, August 2004

11. Brites D, Rodrigues CM, van-Zeller H, Brito A, Silva R. Relevance of 19. Germain AM, Kato S, Carvajal JA, Valenzuela GJ, Valdes GL, Glasinovic
serum bile acid profile in the diagnosis of intrahepatic cholestasis of preg- JC. Bile acids increase response and expression of human myometrial oxy-
nancy in a high incidence area: Portugal. Eur J Obstet Gynecol Reprod tocin receptor. Am J Obstet Gynecol 2003;189:577–582.
Biol 1998;80:31–38. 20. Furhoff AK, Hellstrom K. Jaundice in pregnancy. A follow-up study of the
12. Laatikainen T, Ikonen E. Serum bile acids in cholestasis of pregnancy. series originally presented by L Thorling. II. Present health of the women.
Obstet Gynecol 1977;50:313–318. Acta Med Scand 1974;196:181–189.
13. Kroumpouzos G, Cohen L. Dermatoses of pregnancy. J Am Acad Derma- 21. Nakeeb A, Comuzzie AG, Martin L, Sonnenberg GE, Swarz-Basile D,
tol 2001;7:1––19. Kissebah AH, et al. Gallstones: genetics versus environment. Ann Surg
14. Roger D, Vaillant L, Fignon A, Pierre F, BacqY, Brechot J-F, et al. Specific 2002;235:842– 849.
pruritic dermatoses of pregnancy: a prospective study of 3192 women.
22. Gonzalez MC, Reyes H, Arrese M, Figueroa D, Lorca B, Andresen M,
Arch Dermatol 1994;130:734 –739.
Segovia N, et al. Intrahepatic cholestasis of pregnancy in twin pregnancies.
15. Swedish Medical Birth Register 1970 –2000. Stockholm, Sweden: The
J Hepatol 1989;9:84 –90.
National Board of Health and Welfare, 2001.
23. Kemmet D, Tidman MJ. The influence of the menstrual cycle and preg-
16. Blackwell SC, Wolfe HM, Redman ME, Hassan SS, Berry SM, Treadwell
MC, et al. Relationship between meconium staining and amniotic fluid nancy on atopic dermatitis. Br J Dermatol 1991;125:59 – 61.
volume in term pregnancies. Fetal Diagn Ther 2002;17:78 – 82. 24. Lammert F, Marschall HU, Matern S. Intrahepatic cholestasis of preg-
17. Campos GA, Guerra FA, Israel EJ. Effects of cholic acid infusion in fetal nancy. Curr Treat Options Gastroenterol 2003;6:123–132.
lambs. Acta Obstet Gynecol Scand 1986;65:23–26. 25. Palma J, Reyes H, Ribalta J, Hernandez I, Sandoval L, Almuna R, et al.
18. Israel EJ, Guzman ML, Campos GA. Maximal response to oxytocin of the Ursodeoxycholic acid in the treatment of cholestasis of pregnancy: A ran-
isolated myometrium from pregnant patients with intrahepatic cholestasis. domized, double-blind study controlled with placebo. HEPATOLOGY 1997;
Acta Obstet Gynecol Scand 1986;65:581–582. 27:1022–1028.
APPENDIXE J. “pH Balance: The Importance of Akalinity to Health” extract from D.
Gary Young, ND.’s People’s Desk Reference on Essential Oils, First
Edition, 1999 Pages 156-58
PEOPLE’S DESK REFERENCE FOR ESSENTIAL OILS

pH Balance

The Importance of Alkalinity to Health • Headaches


• Irritability / Mood swings
The unfriendly bacteria and fungi that populate • Indigestion
our intestinal tracts thrive in an acid • Colitis / Ulcers
environment and are responsible for secreting • Diarrhea / Constipation
mycotoxins, which are the root cause of many • Unnary tract infections
debilitating human conditions. In fact, many • Rectal itch / vaginal itch
researchers believe that most diseases can be
linked to blood and intestinal acidity, which
contributes to an acid-based yeast and fungus The ideal pH for the human body runs
dominance. between 7.4 and 7.6. Preserving this
alkalinity (pH balance) is the bedrock on
The symptoms of excess internal acidity which sound health and strong bodies are
include: built. When the blood loses alkalinity and
• Fatigue / Low energy starts to become more acidic, the
• Unexplained aches and pains foundation of health is undermined. This
• Overweight conditions creates an environment where we become
• Low resistance to illness vulnerable to disease and runaway yeast
• Allergies and fungus overgrow
• Unbalanced blood sugar

156
PEOPLE’S DESK REFERENCE FOR ESSENTIAL OILS

The naturally occurring yeast and fungi in the become susceptible to disease and illness.
body thrive in an acid terrain. These same
yeast and fungi are responsible for secreting Many cancers have been linked to
a large number of poisons called mycotoxins, mycotoxins. For example, the fungus
which are believed to be one of the root Aspergillus flavus, which infests stored
causes of many diseases and bilitating peanuts, not only generates cancer in
conditions. laboratory animals but has been documented
When yeast and fungus decline in the body, as the prime culprit in many liver cancers in
so does their production of mycotoxins, the humans.
poisonous waste products and by products
of their life cycles. There are numerous By balancing the body’s pH and creating a
varieties of these mycotoxins, many of which more alkaline environment, you rein in the
are harmful to the body and must be microbial overgrowth and choke off the
neutralized by our immune systems. When production of disease-producing mycotoxins.
our bodies are overwhelmed by large With pH balance restored, the body can regain
quantities of these newfound vigor and health.
toxins, our health becomes impaired, and we

How to Restore Alkalinity

1. Carefully monitor your diet. Avoiding overuse of antibiotics for incidental, minor, or
yeast- cosmetic conditions not only increases the
and fungus-promoting foods is a crucial factor resistance of pathogenic microorganisms, but
in combating excess acidity and fungus over- it kills the beneficial bacteria in your body,
growth. Meats, sugars, dairy products, mush- leaving the mycotoxin-generating yeast and
rooms, and pickled and malted products can fungi intact. This is why many women suffer
be especially acidic. On the other hand, garlic outbreaks of yeast infections after antibiotic
is excellent for controlling fungi and yeast. use.
Other high-alkaline, fungus-inhibiting foods 3. Use essential oils. Many essential oils
include green and yellow vegetables, beans, possess important antimicrobial, antibacterial
and whole uncracked nuts. The natural ratio and antifungal properties. French medical
between acid and alkaline foods in the diet researchers in study after study have
should be 4:1— four parts alkaline foods to documented the healing properties of plant
one part acid. In his book, THE YEAST extracts and their ability to stimulate the
SYNDROME, Dr. Morton Walker outlines immune system and inhibit bacterial growth.
some antifungal diets.
Essential oils work best when the body’s blood
The pH of a raw food does not always and tissues are alkaline. When our systems
determine its acidity or alkalinity in the become more acidic—due to improper diet or
digestive system. Some foods, like lemons, excessive levels of stress—the essential oils
might be acidic in their natural state but when lose some of their effects. So the best way to
consumed and digested are converted into enhance the action of essential oils is to
highly alkaline residues. Thus, the true alkalize your body, and AlkaLime is a first-rate
determinant of a food’s pH is whether it is an tool to accomplish this.
alkaline-ash or acid-ash food. In this case,
lemons are an alkaline-ash food. 4. Using alkaline salts. AlkaLime is an
outstanding source of alkaline salts that can
2. Avoid the use of antibiotics. The help reduce
156
PEOPLE’S DESK REFERENCE FOR ESSENTIAL OILS
psychological tension can be especially
internal acidity. An alkaline environment is damaging to bodily systems and act as a
hostile to fungi, which require acidity to survive prime promoter of acid formation in the body.
and thrive. Lowered yeast and fungus popula- To properly appreciate how acidic stress can
tions translate into lower levels of body- be, just think back to the last time you were
damaging, disease-inducing mycotoxins. seriously stressed-out and had to reach for an
antacid tablet to soothe your heartburn or
5. Lower stress. Emotional and stomach discomfort.

Some of the most common varieties of nega- the body maintain proper pH balance for
tive bacteria, yeast, and fungi that live in the nutrient digestion and absorption. Ideally, the
intestines are inactive. However, when the lactobacillus acidiphilus and bifidobacterium
body is weakened by illness, stress, and bifidus cultures must be combined with
excess acidity caused by stress, these plantain to promote implantation on the
bacteria become active, damaging and intestinal wall.
assuming an invasive mycelic form. Research indicates a significant proportion of
bacteria from many acidophilus supplements
Blends of essential oils high in sesquiter- do not reach the lower intestine alive, or they
penes, such as frankincense, myrrh, and arrive in such a weakened state that they are
sandalwood, can produce profound balancing not of much benefit. This is why combining the
and calming effects on emotions. They work acidophilus and bifidus cultures with plantain is
by affecting the limbic system of our brain, the so important because plantain helps these
seat of our emotions. cultures stick to the intestinal walls.
An even more effective means of fortifying the
6. Boost friendly flora. From three to friendly flora in our intestines is by
four pounds of beneficial bacteria permanently consumption of fructooligosaccharides (also
reside in the intestines of the average adult. known as FOS). FOS is one of the most
Not only are they the first line of defense powerful natural agents for feeding our friendly
against foreign invaders, but they are flora. FOS is made up of medium-chain sugars
absolutely essential for health, energy, and that cannot be used by pathogenic yeast and
optimum digestive efficiency. These intestinal fungi. The end result is that FOS starves fungi
houseguests not only control mucus and while feeding the acidophilus and bifidus cul-
debris, but they produce B vitamins, vitamin K, tures that are our first-line defense against
and maintain the all-important pH balance of disease.
the body.
But FOS is far more than just an outstanding
These friendly flora are also important in means of rebuilding and protecting the benefi-
counteracting and opposing yeast and fungus cial bacteria inside the body. Over a dozen
overgrowth. When our natural cultures are clinical studies have documented the ability of
compromised or disrupted by taking antibiotics fructooligosaccharides to prevent constipation,
or by poor dietary practices, yeast and fungus lower blood sugar and cholesterol levels, and
start growing unopposed and begin colonizing even prevent cancer. (Hidaka et al., 1991; Briet
and invading larger swaths of our internal et al., 1995); Bouhnik et a!., 1996; Kawaguchi
terrain, secreting ever-increasing volumes of et a!., 1993; Luo et al., 1996); Rochat et al.,
poisonous mycotoxins. 1994; Tokunaga et al., 1993).

Using an acidophilus or bifidus supplement, Stevia Select is a supersweet supplement that


like Royaldophilus, may be especially valuable combines stevia with FOS.
in boosting levels of naturally occurring
beneficial bacteria in the body and preventing Testing Your pH
fungal and yeast overgrowth. They also help

157
PEOPLE’S DESK REFERENCE FOR ESSENTIAL OILS
You can easily test your pH at home by the morning and before eating breakfast. Color
purchasing small litmus-paper strips at your changes on the litmus paper will determine pH;
drug store or pharmacy. To get the most check the instructions of your kit for specific
accurate reading, expose the strip to a sample details on how to read the litmus paper.
of your saliva immediately after awakening in

158
FLOW CHART #1.

George W. Singleton, HD. General Human Systems Theory (GHST) Poverty


Systems Analysis--Detailed 2005
FLOW CHART #2.

George Singleton, HD. Dietary Cholesterol & Related Diseases (DCRDS) Human Body
Systems Analysis 2009
jlUNIFIED THEORY OF DIETARY CHOLESTEROL AND RELATED DISEASES AND SYNDROMS (DCRDS) SYSTEMS ANALYSIS HUMAN FLOW CHART _10 TH EDITIO Ramifications of Dietary Cholesterol and Related Animal
Protein, Fat and Other Mucus Residue Metabolism: a.) Daily Dietary Slow and Oblivious Self-Poisoning; b.) Enteric Anaerobic Pathogenic Microorgamism Carbohydrate Fermentation and Lipoprotein Putrefaction Toxemia;
c.) Systemic Mucous Membrane Placque Deformations; d.) Necrosis of Digestive Organs and e.) Systemic Mutagenic and Carcinogenic Generation of the Modern American Diet
Clone White Blood Cells
[LDL] [LCA] [O2] [Serum Urea] BLODD STREAM Serum Uric Acid] {CA] [Hcy] [TG] [FR’s] [pH Acidic Blood] [Mucus Waste] [Athererosclerosis Deformations]
ENODOCRINE GLAND BLOOD NERVE BRAIN
HORMONE SYSTEM VESSELS SYSTEMEM TFK # 2 Brain Cancer
1. HUMAN DECIDES ON 2. MOUTH CAVITY TFK #3 Strokes
INGESTION OF ANIMAL Teeth Mastication TFK #2 Thyroid Cancer) Atherosclerosis Muliple Sclerosis (MS) TFK #11 Suicides TFK #7 Alzheimer’s
TISSUES Salivary Gland Enzymes (#12, especially women Placque Outgrowths Schizophrenia TFK #14 Parkinson’s
Teeth Food Plaque and Microbes (STROKE & HA Bi-Polar Spongiform Encephalopathy
Meat (Muscle) Implicated)
Viscera (Organs, Cardiovascular Heart Disease (Manic-Depressive) Placque Outgrowths
Oil, By Products) Alcohol Addiction Note: Brain uses 75% of Body
Milk/Cheese Drug Addiction Nutrition.
Eggs
AS “PSEUDO/CULTURAL” BRONCHIAL TUBES/ HEART
FOODS LUNGS TFK #1 Heart Attacks (Cardiac Arrest) (HA)
3. ESOPHAGUS TFK #2 Lung Cancer Heart Failure (Congenital Failure)
Food Bolus TFK #4 Asthma TFK # 13 High Blood Pressure
Peristalsis Emphysema Vitamin D Deficiency
Bronchitis
TFK #2 Esophageal Cancer TFK #8 Influenza
Pneumonia
Tuberculosis Bacillis
White Blood Cell 4. STOMACH
Sanitary Reaction Food Bolus
Migration
Heart Burn (Dyspepsia) Note:
Note: 30% Dyspepsia Rate Heliocobactor Pylori (HP)
Acid Reflux Bacteria uses Blood Urea
Ulcer – Stomach as acid buffer and infects
(20% HP) Duodenum Stomach and Duodenum SI
TFK #2 Cancer– Stomach
Duodenum
MICROBIAL ANAEROBIC BACTERIAL TOXEMIA ____________________________________
CA & CDCA => SECONDARY BILE ACIDS LCA & DCA
LYMPHATIC IMMUNE 5. SMALL Food CA & CDCA 9. LARGE Food CHO Fermentation 10. RECTUM/ Normal
SYSTEM INTESTINES Chyme INTESTINES Chyme Protein Putrefaction ANUS Bowel
Note: Clone White (Duodenum/ Peristalsis (COLON) Peristalsis Movement
Blood Cells Jejunum/ (Appendix/ (BM)
Ileum) Ascending
Transverse/
Descending)
#2 TFK Colorectal Cancer (#2) Note: Tape Worm Infestation Rate 50%
Irritated Bowel Syndrome
Appendicitis
Vitamin D Deficiency
__________________________ Small Intestinal Membrane (25 feet) ______ Large Intestinal Membrane (5 feet)____________________________________________
PERIPHERAL AND
ADIPOSE TISSUE 6. BLOOD STREAM ABSORPTION 9. ‘ BLOOD STREAM ABSORPTION
TFK #2 Breast Cancer
(Women, #3) MALE FEMALE
Obesity (60% SEX SEX
ORGANS ORGANS
TFK#2 Prostate Cancer (4) TFK #2 Ovarian\Womb\
SKELETAL/BONE 8. PANCREAS 7.’ GALL 7. LIVER SPLEEN 11. KIDNEYS Prostate Gland Infection Cervix Cancer (12)
MARROW SYSTEM BLADDER (GB) => PRIMARY BILE ACIDS CA & CDCA Activation of Vitamin D3 Excessive Menstruation
High Animal Dietary Calcium Maternal & Infant Death
Clone White Blood Cells
TFK # 6 Diabtes Mellitus GB Stones TFK #12 Liver Cirrhosis TFK # 10 Septicemia TFK #2 Kidney Cancer (7)
Osteoporesis T1 & T2 (80% Dietary Uremia (Dialysis Required)
Arthritis TFK #2 Pancreatic Cancer Cholesterol & Synthesis of Pro-Vitamin D 3 Kidney Stones
Rheumatism (#13) 20% Ca) (80% Ca)
Pancreatitis
12. BLADDER Normal
Urination
MUSCLE CONNECTIVE TISSUE SKIN Vitamin D3 Production via UV Solar Radiation
TISSUE Systemic Lupis (Erythematosus)
[CHO] [LDL] [LCA] [O2] [Urea] BLOOD STREAM [Uric Acid] [CA] [Hcy] [TG] [FR’s] [pH Acidic Blood] [Mucus Waste] [Athererosclerosis Deformations]
Clone White Blood Cells
LEGEND: CO2 Carbon Dioxide O2 Oxygen LCA Lithocholic (Bile) Acid CA Cholic (Bile) Acid CDCA Chenodeoxycholic (Bile) Acid HDL High Density Lipoprotein LDL Low Density Lipoprotein Hcy Homocycteine
n CHO Free Cholesterol FR _ Free radicals Free TG Triglyceride Fatty Acids Ca Ionized Animal and Dairy Calcium
BLACQENDIAN ROYAL COOP ASSOCIATION (BRCA)
ENLIGHTENMENT PUBLICATIONS, INC.
435 Spring Mill Lane
Indianapolis, IN. 46260
317-682-0182
317-282-0617 fax
www.theuniversityofgod.org
gws@theuniversityofgod.org
12/01/2010
PRESS RELEASE:
An Author/Poet/Musician/Sustainable Economic Developer/Nutritional Herbalist/Gardener
George “Aakhun” W. Singleton, III BA., HD., DD.

The CD-ROM THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes:
“The Great Pathophysiological Ramifications” of the Metabolisms of Animal Dietary
Cholesterol, Bile Acid, DNA, Protein and Fat in the Aboriginal Vegan Genome Human Body,
ISBN 978-0-9741724-3-9 is the result of over 2 years of research, development and synthesis work requiring
over $540,000 in resources as a result of being selected as a 2007 (2.3 M Euros) and 2009 European
Union Humanitarian Grantee where his initial target is assisting the American government in improving its
health care system in harmony within the objectives of the United Nations Millennium Project
(http://www.theuniversityofgod.org/Page18.html).

George Aakhun W. Singleton was born January 13, 1949 in Charlotte, North Carolina. Ethnically he is African
American (Black) and Native American (Mississippi Choctaw\North Carolina Cherokee Indian) and African
Moor; i.e. Black Indian or “Blacqendian.” He is a graduate of Shortridge High School in Indianapolis, Indiana
(1966) with major in science and minor in history in a college preparatory curriculum. He is a holder of a
Bachelor of Arts Degree (B.A.) from the University of Chicago (1970), majoring in general biology/pre-
medicine with a minor in history. He has also taken courses in biological medicine having matriculated in both
dental and medical schools and systems analysis.

In 1986 he was given a Doctorate in Herbology (D.H.) Degree and a Doctorate of Divinity (D.D) Degree from
the International Monastery: The University of Eternal Light Consciousness (Dr. Alfred “Roots” Patterson
his apprentice mentor); Los Angeles, CA. based on his development work in “biological agriculture” and
“nutritional herbology” applied to sickness prevention and cure, utilizing the ancient instrument the pendulum
(today termed “radiesthetics/radionics”) from Ancient Egypt/Kemit and documenting the origin of the “bio-
intensive” gardening system of predynastic Egypt. He has demonstrated the reconstructive power of
“experimental anthropology” reestablishing Nutritional Herbology of the Ancient Egypt/Kemit “School of On
(Annu or God). Singleton authored and published under the BRCA/Enlightenment Publications, Inc. in 2004
The Egyptian Mystery School of On (Annu or God): Esoteric Atannulology, Egyptology and
Rastafariology, Volume I ISBN 978-0-9741724-0-8.

Mr. Singleton has been forced by fate initially and later by his own design, to follow a self-taught “generalist” as
opposed to “specialist” approach to education, occupation and personal growth endeavors. He has observed the
Western culture’s “divide and conquer” techniques are the basis to exploitation of native peoples (colonialism,
neocolonialism and indiscriminate arms manufacturing and sales) and exploitation of nature (e.g. air, water, and
soil pollution, humus top soil erosion, animal genocide). That is, fragmented “PhD. Specialist information” instead
of holistic knowledge is the specific “divide and conquer” technique/medium used in the support of racism and
other prejudices leading to the present “earth crisis” of fascism, environmental degradation, ignorance and hate
threatening all life on planet earth.

In his latest work published today December 1, 2010 the e-Book THE PURPLE SEAL:: Breaking the Plague of
Chronic Diseases and Syndromes: “The Great Pathophysiological Ramifications” of the Metabolisms of
Animal Dietary Cholesterol, Bile Acid, DNA, Protein and Fat in the Aboriginal Vegan Genome Human Body
Singleton has had to break through a quagmire of “PhD. Specialist information” in over 15 scientific disciplines to
unmask that the over 70 years of recent suppression of the Great Law of Human Vegan Diet and the reality of
the human vegan genetic genome can not be ignored and suppressed any longer as expressed in the Bible
Genesis 1: 29. According to Singleton the proper unfolding of the Golden Age on earth is dependent on
at least ¼ of America breaking the “Purple Seal” and achieving health and longevity freeing scarce
sustainable economic development resources for the rest of the planet in the next 10 years.
THE PURPLE SEAL:: Breaking the Plague of Chronic Diseases and Syndromes:

Vegan Diet Ancient Egyptian “School of On” (Annu or God) Sun Goddess
Het Heru High Priestess Holding a Duckling, Nakhet Tomb, Circa 1450 BC.

“The Great Pathophysiological Ramifications of the Metabolisms of Animal Dietary


Cholesterol, Bile Acid, DNA, Protein & Fat in the Aboriginal Vegan Genotype Human Body”

By George W. Singleton, III BA., HD., DD.


2007 and 2009 EUROPEAN UNION HUMANITARIAN GRANTEE

On July 6, 2010 the precursor of the Purple Seal called the “Green Paper” was
made available to the Ex-American President Bill Clinton by fax to his wife US
Secretary of State Hillary Rodman Clinton ( the Preface herein includes the fax
cover letter) with the recommendation that the Vegan Diet could reverse his
death threatening cardiovascular heart disease.

On September 20, 2010 the Ex-American President Bill Clinton by the grace of
the Most High God Annu announced during a Wolf Blitzer CNN Interview that he
had lost 24 pounds and had completely reversed his cardiovascular heart disease.

No matter if you are a health professional or layperson; or have a college degree,


high school degree or GED your reading this book will not only allow you to totally
understand the modern plague of chronic diseases and syndromes that has
gripped America including the heart diseases, stroke, the cancers, diabetes,
Alzheimer’s, high blood pressure, liver and kidney diseases, obesity and metabolic
syndrome but show you how to easily prevent them or ameliorate their effects.

The wisdom of the Great Law of Human Vegan Diet and the reality of the human
vegan genetic genome can not be ignored and suppressed any longer as
expressed in the Bible Genesis 1: 29. The unfolding of the Golden Age on earth is
dependent on your breaking the “Purple Seal” and achieving health and longevity.

BRCA/Enlightenment Publications, Inc.


435 Spring Mill Lane
Indianapolis, IN. 46260
317-682-0142
gws@theuniversityofgod.org
http://www.theuniversityofgod.org/Page8.html

ISBN: 978-0-9741724-1-5 $10 (usd)


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