Vous êtes sur la page 1sur 18

Air cleaning systems

Join us on PHARMASTUFF UPDATES group on FACEBOOK


What is a HEPA FILTER?

HEPA is an acronym for “High Efficiency


Particulate Air”

This type of air filter can remove at least 99.97%


of dust, pollen, mold, bacteria and any airborne
particles with a size of 0.3 micrometres (μm)

Join us on PHARMASTUFF UPDATES group on FACEBOOK


Types of HEPA FILTERS
Types Application Performance
A industrial, noncritical 99.97 % @ 0.3 µm
B nuclear containment 99.97 % @ 0.3 µm (certified by DOE)
C laminar flow 99.99 % @ 0.3 µm
D ultra-low penetration air 99.9995 % @ 0.12 µm
ULPA
E stopping toxic, nuclear, 99.999 % efficiency
chemical and biological
threats

Join us on PHARMASTUFF UPDATES group on FACEBOOK


Construction:

HEPA filter is constructed of borosilicate


microfibres in the form of pleated sheet

Sheet is pleated to increase the overall filtration


surface area.

The pleats are separated by serrated aluminum


baffles or stitched fabric ribbons, which direct
airflow through the filter
Join us on PHARMASTUFF UPDATES group on FACEBOOK
Construction
This combination of pleated sheets and baffles acts as
filtration medium.

It is installed into an outer frame made of fire-rated


particle board, aluminum, or stainless steel

The frame-media junctions are permanently glued or


‘‘pot-sealed’’ to ensure a leak proof

Join us on PHARMASTUFF UPDATES group on FACEBOOK


HEPA FILTER

Join us on PHARMASTUFF UPDATES group on FACEBOOK


Filtration Mechanisms:

 1. Inertial Impaction :

particle inertia causes it to leave the flow


streamlines and impact on the fiber.

Join us on PHARMASTUFF UPDATES group on FACEBOOK


Filtration mechanisms:

2. Diffusion:

The particles traverse the flow stream, they


collide with the fiber and are collected.

Join us on PHARMASTUFF UPDATES group on FACEBOOK


Filtration mechanisms:
 3.Interception :

These mid-sized particles follow the flow stream as it


bends through the fiber spaces. Particles are
intercepted or captured when they touch a fiber.

Join us on PHARMASTUFF UPDATES group on FACEBOOK


HEPA in Laminar air flow systems

Laminar air flow systems are used for cleaning air in


aseptic rooms.

In laminar air flow systems,clean air is obtained


through HEPA filters

This air flows at a speed of 100 ft/min & sweeps dust


particles making entire room free of particulate
matter

Join us on PHARMASTUFF UPDATES group on FACEBOOK


Classification of clean rooms
Six classes have been established to designate
cleanroom cleanliness .

 Class 1
 Class 10
 Class 100
 Class 1,000
 Class 10,000
 Class 100,000

Join us on PHARMASTUFF UPDATES group on FACEBOOK


Types of Laminar air flow systems

Laminar air flow systems are of 3 types

1. Downward flow systems


2. Horizontal flow systems
3. Wall to floor flow systems

Join us on PHARMASTUFF UPDATES group on FACEBOOK


Downward flow systems
This system consists of false floor
& ceiling

The air is filtered through pre-


filters ,electroststic filters and
HEPA filters in sequence

These 3 filters are placed in false


ceiling

From the false floor,a small


portion of filtered air is
recirculated in to false ceiling
through a recirculation duct.
Join us on PHARMASTUFF UPDATES group on FACEBOOK
Horizontal flow systems
The air is filtered through
prefilters ,HEPA filters which
are placed in lateral walls.

Air is recirculated through


punched plate wall or
recirculation duct.

Achievement of complete
sterile conditions is not
possible because the airflow is
not focussed on working area

Join us on PHARMASTUFF UPDATES group on FACEBOOK


Wall to floor flow systems:
The filtered air enters from lateral wall with an
inclined flow towards the floor.

In this system working area is offered with high


aseptic conditions.

This system is more expensive

Join us on PHARMASTUFF UPDATES group on FACEBOOK


Conditions That Will Damage HEPA Filters
Moisture: 95-100% relative humidity

Hot air: greater than 275 °F

Fire: direct fire or high concentrations of particulate


matter produced by fire

High pressure: 8 in. of water, gauge (in. wg) internal or


differential across filter media

Join us on PHARMASTUFF UPDATES group on FACEBOOK


Conditions That Will Damage HEPA Filters
Corrosive : dilute moist or moderately dry concentrations
of acids and caustics

Any acid and some caustics will attack uncoated aluminum


separators

Hydrofluoric acid will attack the media

Nitric acid

Shock pressures

Join us on PHARMASTUFF UPDATES group on FACEBOOK


Shipment,storage,handling:
 
The HEPA filter is extremely fragile and should be
shipped, stored, and handled in the same manner as
delicate instrumentation. Personnel responsible for
receiving and handling HEPA filters should receive
training in proper handling technique. All incoming
HEPA filters should be visually inspected for apparent

Join us on PHARMASTUFF UPDATES group on FACEBOOK

Vous aimerez peut-être aussi