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KEYWORDS
Anemia Pregnancy Hemoglobin Iron Folate
KEY POINTS
Physiologic anemia occurs in pregnancy because plasma volume increases more quickly
than red cell mass.
Anemia in pregnancy is defined as hemoglobin and hematocrit lower than 11% and 33%
in the first trimester, 10.5% and 32% in the second trimester, and 11% and 33% in the
third trimester.
An increase of 60 mg of elemental iron daily is recommended in the second and third tri-
mesters because an average diet cannot meet the increased iron demand in pregnancy.
Iron deficiency anemia accounts for 75% of all anemia in pregnancy.
It is recommended to screen for and treat iron deficiency anemia in pregnancy because
treatment to maintain maternal iron stores may be beneficial to neonatal iron stores.
INTRODUCTION
a
Department of Maternal Fetal Medicine, University of Connecticut Health Center, 263
Farmington Avenue, Farmington, CT 06030, USA; b Department of Maternal Fetal Medicine,
Hartford Hospital, 85 Jefferson Street, Suite 625, Hartford, CT 06102, USA
* Corresponding author.
E-mail address: khorowitz@resident.uchc.edu