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AGAROSE MOLECULE

OH OH
O
O
OH
O O
H O
OH HO
n

VO LU M I Z I N G B I O D E G R A DA B L E
I N J E C TA B L E I M P L A N T
ON THE CUTTING EDGE OF SCIENCE
INTRODUCTION

Advanced Aesthetic Technologies Inc. (AAT)

is a USA based company developing bio-

technologies in the aesthetic medical field,

driven by quality and excellence. Algeness®

is the culmination of 10 years of scientific and

clinical research and is intended for physicians

in cosmetic treatments seeking an efficient,

high quality, safe filler.

AAT’s Algeness® is an exceptional 100% natural

and biodegradable injectable implant with a

unique injection technique enabling clinicians

to Master Your Results®.


MASTER YOUR RESULTS ®

DERMIS
1% Agarose (Low density)

N AT U R A L YO U T H F U L L O O K SUPERFICIAL 2,5%
Sub-dermal
1,5%
Agarose (Low density)
H
OH OH

O
O

OH
O
O

HO
O
OH

HYPODERMIS Agarose Sub-dermal n

W I T H I M M E D I AT E R E S U LT S
(High density) 3,5%
Deep
DEEP sub-dermal Agarose (High density)
HYPODERMIS hypo-dermis and
supra peri-osteal
MUSCLE
BONE

ALGENESS® A BREAKTHROUGH
IN THE SUBDERMAL FILLER INDUSTRY Algeness agarose gel structure Algeness fillers depth of injection Immediate and safe mastered result.
Agarose is an hydrocolloid molecule
containing water in its structure

Algeness® is a biomaterial consisting of For the first time in the aesthetic medi-
a purified agarose gel (polysaccharide), cine history, a 100% natural, biocompa-
derived from a sophisticated manufactu- tible and biodegradable injectable im-
ring process. plant is available on the market fulfilling
The molecular and biophysical properties the expectations and requirements of BUILDING YOUR CONFIDENCE
of AAT’s agarose make it a breakthrough the most demanding practitioners. KNOWING ALGENESS® IS:
in the filler’s injection technology.

n 1 00% Natural and n Immediate Volumizing: n Non allergenic;


S P E C I F I C F I L L I N G T R E AT M E N T S TO G I V E biodegradable “What you see is what Algeness® offers
AN ANSWER TO CUSTOMER NEEDS injectable implant; you get” Algeness® excellent tolerability
Algeness® is composed does not contain and biocompatibility
of an Agarose gel, cross-linked HA
Women today are demanding better know that dermal fillers are not all the totally biocompatible n Minimal irritation
This avoids having
and safer products from their beauty same and they understand and know the to the human body and & inflammation due to
to wait to see the
professionals to enhance and improve their importance of all-natural, biocompatible does not containing the absence of foreign
hydrophilic effect of HA
appearance and sense of well-being. and biodegradable ingredients injected cross-linked synthetic body reactions. [1-2]
fillers whith can take
As they search for the best solution, they safely into their skin. chemicals (BBDE) 2-4 weeks for the full n Extremely low
associated with effects to be seen. migration.
Hyaluronic Acid (HA)
fillers. [3] n Long lasting results of
A L G E N E S S ®: T H E N E W B E N C H M A R K over 12 months, proven
by clinical studies. [1-2]
FOR SUBDERMAL FILLERS

The fulfilment of the patients’ require- injection technique which we call “Master
ments is a challenge when the results Your Results®” The right filler is very im-
must be achieved immediately and safely portant, when the physician is requested
Bibliographic References:
with a all natural look and this can be to deliver immediate results safely, confi- [1] Joergensen, P., M.D. and Adamsen, R. “Efficacy, safety and rate of absorption of Agarose for facial
done with the confidence of a controlled dently and with precision. soft-tissue augmentation. Data on file
[2] Comparative implantation in mice: Wake Forest University. 2013 and 2014
[3] Motolese, P. MD Agarose gel long-lasting absorbable filler
Data on file. (Member of SIES and Prof. AMS – Bologna)
[6]

[1 ]

[7]

Product LD
1%
HD
1,5%
VL
2,5%
DF
3,5%
[5]
Charm

Composition 1% Agarose 1.5 % Agarose 2.5% Agarose 3.5% Agarose


(Very low density) (Low density) (High density) (High density)
99% sterile saline 98 .5% sterile saline 0.5% non 0.4% non [4]
crossed-linked HA crossed-linked HA
97% sterile saline 96.1% sterile saline

[3] [2]
Indication Tear trough Marionette lines, Medium-deep volumizing Deep volumetric filling
Lips augmentation wrinkles, and furrows Wrinkles, furrows and Cheeks , jawline and chin
and contouring Lip augmentation folds Nasolabial folds
and contouring Cheeks, jawline and chin Malar-zygomatic arch
Oral commissure Nasolabial folds Submalar
Oro-mandibular folds Malar and Submalar Non surgical
Non-surgical rhinoplasty nose rhinoplasty

Technique Linear, Linear, Linear, Linear,


Retrograde Retrograde Retrograde Retrograde

Injection Immediately Immediately Subcutaneous Deep soft tissue


depth Subcutaneous Subcutaneous supra-periosteal

Follow up After 7-10 days if After 7-10 days if After 7-10 days if After 7-10 days if
additional corrections additional corrections are additional corrections additional corrections A R E A S O F A P P L I C A T I O N
are required required are required are required

Duration 3 – 4 months or more 4 – 8 months or more 8 – 12 months or more 10 – 15 months or more

ALGENESS ® LD 1 % ALGENESS ® HD 1 .5 % ALGENESS ® VL 2.5 % ALGE NE SS ® DF 3.5%


Volume 0.5 ml 1.4 ml 1.4 ml 1.4 ml
Indications Indications Indications Indications
[ 1 ] Tear trough [ 3 ] Marionette lines, [ 5 ] Medium-deep volumizing Deep volumetric filling
Needle size 30 G 30 G 27G 27G
[ 2 ] Lips wrinkles and furrows [ 6 ] Wrinkles, furrows and folds Cheeks, jawline and chin

Each box 2 disposable “full-use” 2 disposable “full-use” 2 disposable “full-use” 2 disposable “full-use”
Depth of injection: [ 2 ] Lip augmentation Cheeks, jawline and chin [ 7 ] Malar-zygomatic arch
contains 0.5 ml double Luer Lock 1.4 ml double Luer 1.4 ml double Luer Lock 1.4 ml double Luer Lock subdermal and contouring Nasolabial folds temple Submalar
syringe systems, Lock syringe systems, 2 syringe systems, syringe systems, [ 4 ] Oral commissure Non-surgical rhinoplasty Depth of injection:
2 needles per syringe. needles per syringe. 2 needles per syringe. 2 needles per syringe. Oro-mandibular folds Depth of injection: Subcutaneous
Depth of injection: supra-periosteal Supraperiosteal
Shelf life 2 years 2 years 2 years 2 years subdermal Subcutaneous

THE U LT I M AT E TECHNIQUE TO MASTER YOUR R E S U LT S ®


D I S T R I B U T O R S TA M P

For professional use only

A d v a n c e d A e s t h e t i c Te c h n o l o g i e s , I n c

One Brookline Place, Suite 427 - Brookline, MA 02445

www. a l g e n e ss .co m - i n fo @ a l g e n e ss .co m

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