12122t2015

o Neural control of digestion is controlled largely by the

parasympathetic nervous system, and local (enteric) reflexes. :-_-- -ln6Jiinal piiise ot oaCiiii Secreton_--- .

::
. Activation of the parasympathetic system results in secretion i,. (- 10% of total) i

of digestive juices, increased motility of the stomach, and i-tg"P:3T9*G*":l!"_"_Tlitd_i$_llol!*1T-tl_trr!91!_9_dr9_q_e"ITl,

slowing down movement of food from the stomach to small
intestine.
lmportant aspect of intestinal phase is feedback
o Stimuli: Thought, sight, taste of smell of food; distension of Gl regulation and inhibition
tract; chemoreceptors detecting nutrients, pH.

. Example: Thought, chewing, or taste of food activates
parasympathetic system, resulting in increased release of
mucus, HCl, and pepsin in the stomach.
The goal of this is to prepare the stomach for oncoming fqgd.
lnvolves interactions between duodenal contents
and duodenal hormones, including their actions
on pancreas, liver, gall bladder, and stomach
26

1. Cephalic Phase of 2. Gastric Phase ot

Gastric Secretion (apprcx. Gastric Secretion o Gastrin:
oftotal) (approx 60% of total)
30'/6
- produced from the stomach (G cells)
(initiated by brain) (initiated by gastric events)
- release increased by stomach distension,
peptides, amino acids, alcohol, caffeine,
parasympathetic innervation
- release inhibited by highly acidic pH (< 2.0)
- functions: increases gastric (stomach) secretions
(primarily HCI); increases histamine release;
increases gastric motility; opens pyloric sphincter
(between stomach and small intestine), relaxes
i leocecal sph n cter, sti m u lates g rowth of gastric
i

mucosa.