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Antianginal drugs are used primarily to restore the balance between the
oxygen supply and demand of the heart. These drugs dilate the coronary
vessels to increase the flow of oxygen to the ischemic regions. Other than
that, they also decrease the workload of the heart so the organ would have
less demand for oxygen. Learn about antianginal drugs, nitrates, beta-
blockers, and calcium channel blockers in this simplified guide for nursing
pharmacology.
Contents
1 Table of Common Drugs and Generic Names
2 Disease spotlight: Coronary Artery Disease
3 Nitrates
o 3.1 Description
o 3.2 Therapeutic Action
o 3.3 Indications
o 3.4 Pharmacokinetics
o 3.5 Contraindications and Cautions
o 3.6 Adverse Effects
o 3.7 Interactions
o 3.8 Nursing Management
4 Beta-Adrenergic Blockers
o 4.1 Description
o 4.2 Therapeutic action
o 4.3 Indications
o 4.4 Pharmacokinetics
o 4.5 Contraindications and Cautions
o 4.6 Adverse Effects
o 4.7 Interactions
o 4.8 Nursing Considerations
5 Calcium-Channel Blockers
o 5.1 Description
o 5.2 Therapeutic Action
o 5.3 Pharmacokinetics
o 5.4 Contraindications and Cautions
o 5.5 Adverse Effects
o 5.6 Interactions
o 5.7 Nursing Considerations
6 Practice Quiz: Antianginal Drugs
7 See Also
8 Further Reading and Resources
acebutolol Sectral
esmolol Brevibloc
timolol Blocadren
amlodipine Norvasc
Calcium-channel blockers
diltiazem Diltiazem, Diltiazem SR
Classification Generic Name Brand Name
nicardipine Cardene
Others:
Description
Therapeutic Action
Indications
Pharmacokinetics
Route Onset Duration
Interactions
Nursing Management
Nursing Assessment
Nursing Diagnoses
Evaluation
Beta-Adrenergic Blockers
Description
Therapeutic action
Main effects include decreased blood pressure, contractility and
heart rate by blocking the beta-receptors in the heart and
juxtaglomerular apparatus of the kidneys. These combined effects
reduce the oxygen demand of the heart.
Usually used in therapy with nitrates because of reduced adverse
effects and increased exercise tolerance.
Not indicated for variant angina because therapeutic effect of drugs
can cause vasospasm.
Indications
Pharmacokinetics
Route Onset Peak Duration
T1/2: 3-4 h
Metabolism: liver
Excretion: kidney (urine)
Adverse Effects
Interactions
Nursing Considerations
Nursing Assessment
Nursing Diagnosis