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AFR: Africa;
EUR: Europe;
Conclusion
382 million people have diabetes in 2013; by 2035 this will rise to 592 million
Diabetes TF sales:
16,6% of total TF sales
Source: Applix,
Incl. Diben/ DRINK, Fresbind diabetes,
Fresubin DB control / DRINK, w/o
1000 ml
Year 1*: 10 000 Unit / 63 000 Euro
Year 3°: 60 000 Units /380 000 Euro
Nutritional
Rational
Recommendation
Low SFA Improve lipid control
High MUFA Reduce cardiovascular risk
With DHA & EPA from fish oil Enhance glycaemic control
500 ml EasyBag:
article code 7111221 - D-GB-F-P-NL
article code 7200221 - E-S-N-PL-SI
1.000 ml EasyBag:
article code 7111231
language combination not yet defined
(available as of 2015)
Shelf life:
- at launch 9 months
- as soon as sufficient stability data is available the shelf life
will be extended to 12 months
Tube Feed
• Normo-caloric: Diben
(Fresubin DB control)
Fresubin diabetes
• High-caloric/High protein: Diben 1,5 kcal HP
ONS
• High-caloric / High protein: Diben Drink
(Fresubin DB control DRINK)
• High-caloric / High protein: Diben Creme
(Fresubin DB control DRINK)
Powder
• Normo-caloric: Diben Powder
Protein Milk
Fat Sunflower oil, rapeseed oil, MCT oil, soy oil, fish oil
Sodium 55 mg 550 mg
ß-Carotene 0.2 mg 2 mg
Vitamin D3 2.0 µg 20 µg
Vitamin E 2.3 mg 23 mg
Vitamin K1 10 µg 100 µg
Vitamin B1 0.2 mg 2.0 mg
Vitamin B2 0.26 mg 2.6 mg
Niacin 2.4 mg 24 mg
Vitamin B6 0.24 mg 2.4 mg
Vitamin B12 0.40 µg 4.0 µg
Pantothenic acid 0.7 mg 7.0 mg
Biotin 7.5 µg 75 µg
Folic acid 40 µg 400 µg
Vitamin C 12 mg 120 mg
Choline 55 mg 550 mg
° ADA 2013 : The best macronutrient mix “appears to vary depending on individual circumstances”, “total caloric intake must be
appropriate to weight management goals” & “will depend on the metabolism status of the patient” (e.g. lipid profile).
120 –
100 –
80 –
60 –
40 –
█ WHO/FAO Reference Amino acid pattern
mg/g protein
20 –
Methionine
Tryptopan
Threonine
Isoleucine
Histidine
Cysteine
Leucine
Lysine
Valine
0–
With Isomaltulose
slowly digested and absorbed in the small intestine
*the glycaemic index of Diben 1,5 kcal HP was measured according to the standard in
vivo FAo/WHo method and has a value of 22 which is defined as low.
Definition (FAo/WHo):
low: GI ≤ 55, medium: Gi = 56—69, High: Gi ≥ 70
Benefits of Isomaltulose
High GI
No relative
hypoglyceamia Steady and longer
Low GI engery supply
Decrease of blood
glucose level below
initial value
www.beneo-palatinit.com
© Copyright Fresenius Kabi Deutschland GmbH 36
Diben 1,5 kcal HP
Key features and benefits
Triglyceride
LCTs are absorbed via levels
the intestinal lymphatic in blood
ducts and transported
in chylomicrons into the
systemic circulation.
LCT
MCTs are hydrolysed
and transported to the MCT
liver via the portal vein
where they are rapidly
oxidised to ketones.
Chromium
Necessary for normal glucose tolerance and lipid metabolism
ability to potentiate the actions of insulin in facilitating
cellular uptake of glucose
Chromium
Supplementation in patients with glucose intolerance and
diabetes
increase insulin sensitivity and improve glucose metabolism
Low in Sodium
To meet the needs of hypertesive patients
Low in Sodium
Nutritionally complete
in 1000 ml = 1500 kcal
to provide all nutrients in a low volume
to be suitable for patients in need of
volume restriction
Dosage Recommendation:
nutrition
Contains MCT
- Improves tolerance
- and contributes to blood lipid control
High in MUFA
and modified EPA and DHA
With MCT from fish oil to
Providing carbohydrate profile
to contribute to contribute to
concentrated is
blood lipid control
nutrition improving the healthy blood lipid
and
in a metabolic situation levels and
good intestinal
low volume of patients with help to protect from
tolerance
impaired glucose cardiovascular
metabolism disease
Protein (en%) 20 17 20 20 18
Modified CHO
Green-tea extract -- -- --
Energy density (kcal/ 100ml) 150 150 150 150 120 120 1,23 120 120
560
Lactose (g/ 100ml) ≤0,048 ≤0,02 <0,1 <0,1
Chromium (mcg/100ml) 40 9 9 20 16 7 7,5 7,5 16
Vit C (mg/100ml) 12 13 13 32,5 26 12 4,6 4,6 24
Vit E (mg/100ml) 2,3 2,6 2,6 4,8 3,9 2,4 1 1 3,6[IU]
ß‐Carotene (mg/100ml) 0,2 0,0 0,0 3,3 2,7 none none
Flavonoids (mg/100ml) 0 none none none none none
Advantages Advantages
Glucerna 1.5 Diben 1.5 kcal HP
Lower osmolarity
Advantages Advantages
Novasourse Diabet Plus Diben 1.5 kcal HP
Flavoured, can be used for sip and tube Contains EPA and DHA from fish oil
feeding
Higher caloric density
Contains ß-Carotine
Product description
Target patients
Features & Benefits at a
glance
Nutritional and prescribing
information
© Copyright Fresenius Kabi Deutschland GmbH 62
Promotional support –
Sales Folder
4-pager
Product description
Highlight & Details on key
features & benefits
Nutritional and prescribing
information
High
GI
Decrease of
blood glucose
level below
initial value
© Copyright Fresenius Kabi Deutschland GmbH 65
Promotional support –
Sales Folder
Standard enteral
Rationale
formula
Low in CHO
High in CHO For better glycaemic control
high in fat high in MUFA, & improved lipid metabolism
low in fat
with MTC & EPA +DHA
Normalisation of stool
Fibre to meet RDA for Balanced dietary fibre mix frequency and consistency to
healthy people with prebiotic inulin avoid diarrhoea or
constipation
Protein to meet RDA for High in protein with high To prevent exacerbation of
healthy people biological value protein catabolism
With MCT