hat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in understanding
that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand, many
scientistsbelieved that there would quite literally be no more mysteriesabout human life. As
Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the human
genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to understand
every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how they
function, there were undeniable signsthat a piece of the puzzle was still missing. And it was a
criticalpiece with respect to providing a full and complete view of human health and the role of
genes in the development of disease.“As it turns out,” Issa notes, the picture was incomplete
because“the sequence of DNhat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

1
However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DNhat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec
1

However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DNhat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DNhat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DNhat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

T
he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DNhat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

.

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DNhat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction
“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DNhat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DN

hat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107
Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DNhat Epigenetics Can Mean For You

...............................................103
Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DNhat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DNhat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

1
However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DN

hat Epigenetics Can Mean For You

...............................................103

Sources

......................................................................................................107

Index

..........................................................................................................111

How to Reprogram Your DNA for Optimum Health

Introduction

“We were all brought up to think the genome was it.It's really been awatershed in
understanding that there is something beyond the genome.”

—C. David Allis, Rockefeller University molecular biologist

he announcement of the Human Genome Project in 1990, which was intended to produce the
first complete map of thehuman genome, was met with unparalleled enthusiasm and
highexpectations. Many scientists predicted that the success of theproject would radically
reconfigure not only the world of medi -cine, but the world as we know it. Once the estimated
25,000genes that make up human DNA had been sequenced, we wouldhave unlocked the
genetic key to how we look, feel, think, andbehave. With the human genome map in hand,
many scientistsbelieved that there would quite literally be no more mysteriesabout human
life. As Jean-Pierre Issa, professor of microbiology at Temple University, puts it, “When the
human genome wassequenced, some scientists were saying, ‘That’s the end. We’regoing to
understand every disease. We’re going to understandevery behavior.’”

Adelle LaBrec

However, when the Human Genome Project finally concludedin March of 2000, it quickly
became clear that these hopes hadbeen overly optimistic to some degree. While the $3
billionproject had indeed furnished a wealth of fascinating new factsabout genes and how
they function, there were undeniable signsthat a piece of the puzzle was still missing. And it
was a criticalpiece with respect to providing a full and complete view of human health and the
role of genes in the development of disease.“As it turns out,” Issa notes, the picture was
incomplete because“the sequence of DN