Académique Documents
Professionnel Documents
Culture Documents
Termination of Resuscitation
Fri, Dec 1, 2017 By Alysha Joseph, BS , Brandon Morshedi, MD , Raymond L.
A 2016 study conducted in Paris, France, indicated that OHCA patients had
a survival rate of 0% if the following three criteria were met by the
patient: 1) The patient didn't arrest in front of rescuers; 2) The patient had
a non-shockable rhythm; and 3) The patient didn't respond to two rounds
2
of epinephrine.
A rapid rise in EtCO2 during CPR can indicate ROSC due to the improved
oxygen delivery to tissues that were compromised during cardiac arrest. A
sustained drop or low EtCO2 over time is now understood to be a sign of a
futile resuscitation attempt.
The study suggests that EtCO2 goals during resuscitation may be higher
than previously believed, and that further studies on clinical targets
during resuscitation are necessary to diminish morbidity and mortality
after cardiorespiratory arrest.
In a study conducted by the authors, the medical directors from the U.S.
Metropolitan Municipalities EMS Medical Directors Consortium (the
"Eagles" Coalition), which includes some of the largest EMS systems in the
world, were surveyed on this issue. The purpose of the study was to elicit
the current role of EtCO2 in TOR.
LACKING CONSENSUS
The results indicate a lack of consensus among survey participants
regarding the guidelines used for TOR regarding the use of EtCO2 levels
for medical decision-making.
The second question showed that there's no real consensus with regard to
ranking the importance of the listed clinical factors in the decision to
terminate resuscitation.
The survey also revealed that more than 85% of participants believe the
role of EtCO2 in TOR has changed in the past decade, and 84% of agencies
have terminated resuscitation in cardiac arrests where EtCO2 is > 20
mmHg.
This finding reveals that the threshold of EtCO2 < 10 mmHg at the 20-
minute mark of resuscitation as the predictive marker of non-
survivability of OHCA, which was set as a result of the 1997 article
discussed previously, may need to be re-evaluated.
It's interesting to find such a wide variety of opinions among expert EMS
medical directors when it comes to determining which clinical factors are
most important for TOR. This variability could affect survival, as under-
or over-emphasizing specific clinical factors could result in premature
termination or inappropriately prolonged resuscitative efforts.
The authors believe that the various factors used in the decision for TOR
in the out-of-hospital setting should be standardized for all patients.
CONCLUSION
The survey results confirm the lack of standardization in guidelines used
for TOR and suggest that the use of EtCO2 levels as a guide in determining
field TOR may need further examination. Further research may clarify
both the role of EtCO2 as well as potential pitfalls of its use in TOR.
REFERENCES
1. McNally B, Robb R, Mehta M, et al. Out-of-hospital cardiac arrest surveillance-
Cardiac Arrest Registry to Enhance Survival. MMWR Surveill Summ. 2011;60(8):1-19.
By
Alysha
Joseph,
BS
Brandon Morshedi, MD
Brandon Morshedi, MD, is an EMS fellow in the
Department of Emergency Medicine at the University of
Texas Southwestern Medical Center.