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Teletherapy Physics – session 1

Alan McWilliam

alan.mcwilliam@christie.nhs.uk

The Christie NHS


NHS Foundation Trust
Contents
1. X-ray beam physics - introduction
2. Electron beam physics - introduction
3. Treatment planning glossary(1)
4. Treatment planning glossary(2)
5. PDD variation
6. Surface dose
7. Hand calculation data
8. Output factors
9. Heterogeneity corrections

The Christie NHS


NHS Foundation Trust
3. Treatment Planning Glossary (1)
1. X-ray beam physics - introduction
2. Electron beam physics - introduction
3. Treatment planning glossary(1)
4. Treatment planning glossary(2)
5. PDD variation
6. Surface dose
7. Hand calculation data
8. Output factors
9. Heterogeneity corrections

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NHS Foundation Trust
3. Treatment Planning Glossary(1)

• Beam • Source to surface distance


• Collimator (SSD)
• Radiation field • Source to Axis distance
• Principal plane (SAD)
• Beam axis • Depth in phantom
• Superposed beams • Depth of maximum dose
(build-up depth)
• Iso-centre
• Percentage depth dose
• Phantom
• Beam Profile
• Tissue equivalence
• Equivalent field

The Christie NHS


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An X-ray beam

• Principle plane: a plane


containing the beam axis
and parallel to the face of
one or other collimator.
• Beam axis: the axis about
which the collimator rotates
• Radiation field: a plane
section through the beam
perpendicular to the beam
axis.

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3. Treatment Planning Glossary (1)

• Beam • Source to surface distance


• Collimator (SSD)
• Radiation field • Source to Axis distance
• Principal plane (SAD)
• Beam axis • Depth in phantom
• Superposed beams • Depth of maximum dose
(build-up depth)
• Iso-centre
• Percentage depth dose
• Phantom
• Beam Profile
• Tissue equivalence
• Equivalent field

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Isocentre

SAD

Isocentre

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3. Treatment Planning Glossary (1)

• Beam • Source to surface distance


• Collimator (SSD)
• Radiation field • Source to Axis distance
• Principal plane (SAD)
• Beam axis • Depth in phantom
• Superposed beams • Depth of maximum dose
(build-up depth)
• Iso-centre
• Percentage depth dose
• Phantom
• Beam Profile
• Tissue equivalence
• Equivalent field

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NHS Foundation Trust
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SSD
• Source-surface distance
• Phantom depth d
max

d,depth

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3. Treatment Planning Glossary (1)

• Beam • Source to surface distance


• Collimator (SSD)
• Radiation field • Source to Axis distance
• Principal plane (SAD)
• Beam axis • Depth in phantom
• Superposed beams • Depth of maximum dose
(build-up depth)
• Iso-centre
• Percentage depth dose
• Phantom
• Beam Profile
• Tissue equivalence
• Equivalent field

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NHS Foundation Trust
Build up depth
electrons

X-rays

electrons

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Build up depths

Energy Dmax (mm)

C0-60 5

4MV 10

6MV 16

8MV 20

18/20MV 30

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3. Treatment Planning Glossary (1)

• Beam • Source to surface distance


• Collimator (SSD)
• Radiation field • Source to Axis distance
• Principal plane (SAD)
• Beam axis • Depth in phantom
• Superposed beams • Depth of maximum dose
(build-up depth)
• Iso-centre
• Percentage depth dose
• Phantom
• Beam Profile
• Tissue equivalence
• Equivalent field

The Christie NHS


NHS Foundation Trust
100cm

120
100
dmax 80

PDD (%)
60
Depth A 40
20
0
0 10 20 30
Depth (cm)

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3. Treatment Planning Glossary (1)

• Beam • Source to surface distance


• Collimator (SSD)
• Radiation field • Source to Axis distance
• Principal plane (SAD)
• Beam axis • Depth in phantom
• Superposed beams • Depth of maximum dose
(build-up depth)
• Iso-centre
• Percentage depth dose
• Phantom
• Beam Profile
• Tissue equivalence
• Equivalent field

The Christie NHS


NHS Foundation Trust
Beam Profile

• Flat at depth – wedge, target and lateral


scatter
100
Norm alised dose (%)

80

60

40

20 dmax
At depth
0
-15 -10 -5 0 5 10 15
Position (m m )
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4. Treatment Planning Glossary (2)
1. X-ray beam physics - introduction
2. Electron beam physics - introduction
3. Treatment planning glossary(1)
4. Treatment planning glossary(2)
5. PDD variation
6. Surface dose
7. Hand calculation data
8. Output factors
9. Heterogeneity corrections

The Christie NHS


NHS Foundation Trust
4. Treatment Planning Glossary (2)

• Isodose line • Back Scatter Factor


• Isodose plot • Tissue Maximum Ratio
• Primary Dose • Tissue Phantom Ratio
• Scatter dose • Tissue Air Ratio
• Scatter factor • Tissue Standard Ratio
• Peak Scatter Factor

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Isodose
Plot

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• Example isodose distributions from Pinnacle

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Focal Spot
Beam
Penumbra
Inner Jaw
100

Norm alis e d dos e (%)


80

Outer Jaw 60

40

20 dmax
At depth
0
-15 -10 -5 0 5 10 15
Position (mm)

The Christie NHS


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4. Treatment Planning Glossary (2)

• Isodose line • Back Scatter Factor


• Isodose plot • Tissue Maximum Ratio
• Dose decrement line • Tissue Phantom Ratio
• Primary Dose • Tissue Air Ratio
• Scatter dose • Tissue Standard Ratio
• Scatter factor
• Peak Scatter Factor

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Target Primary photon
Flattening filter Head-scattered
Collimators photon
Phantom-scattered
photon

Phantom

Scattered electrons
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5. PDD Variation
1. X-ray beam physics - introduction
2. Electron beam physics - introduction
3. Treatment planning glossary(1)
4. Treatment planning glossary(2)
5. PDD variation
6. Surface dose
7. Hand calculation data
8. Output factors
9. Heterogeneity corrections

The Christie NHS


NHS Foundation Trust
5. PDD variation

• PDD increases with increasing energy because of an


increase in beam penetrating power

• PDD increases with increasing SSD because of a


decreasing effect of z on the inverse square factor

• PDD increases with increasing field size because of


increased scatter contribution to points on the central axis

• PDD increases when wedge added

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PDD variation with energy

100.0
90.0 4MV (FS = 10cm)
80.0 6MV (FS = 10cm)
70.0
8MV (FS = 10cm)
PDD (% )

60.0
20MV (FS = 10cm)
50.0
40.0
30.0
20.0
10.0
0.0
0 10 20 30 40
Depth (cm)

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PDD variation with SSD

120.0

100.0 100

80.0 160
PDD (%)

60.0 60
40.0

20.0

0.0
0 5 10 15 20 25 30 35
Depth (mm)
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Inverse Square
 SSD  d max 
2

INVSQ factor   
 SSD  d 

4.5
4
3.5
3
Dose

2.5
2
1.5
1
0.5
0
0 50 100 150
Distance
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4MV PDD variation with field size

120

100 3.2 10.0

80 20.0 40.0
PDD (% )

60

40

20

0
0 5 10 15 20 25 30 35
Depth (cm)
The Christie NHS
NHS Foundation Trust
PDD 10cm deep variation with field size

PDD at 10 cm deep
1.200
1.150
1.100
1.050
PDD(%)

1.000
0.950
0.900
0.850
0.800
0.0 10.0 20.0 30.0 40.0 50.0 60.0
Field Size (cm)

The Christie NHS


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Variation of PDD with field size for
two energies

(10cm deep) 5 x 5 cm 10 x10 cm 15 x 15 cm

300kV 25.0% 33.5% 40%


50 cm SSD

8MV 68.5% 71.0% 72.5%


100 cm SSD

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PDD variation with a wedge added

• The wedge preferentially attenuates the low


energy photons in the beam. This leads to
beam hardening and subsequent increase in
percentage depth dose.
• The wedge not only adds asymmetry to the
beam profile but also adds asymmetry to the
photon spectra and the photon and electron
scatter.

The Christie NHS


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6. Surface Dose
1. X-ray beam physics - introduction
2. Electron beam physics - introduction
3. Treatment planning glossary(1)
4. Treatment planning glossary(2)
5. PDD variation
6. Surface dose
7. Hand calculation data
8. Output factors
9. Heterogeneity corrections

The Christie NHS


NHS Foundation Trust
6. Surface Dose

• The surface dose is not negligible because


• Electrons are backscattered from x-ray interactions
near the surface
• Electrons are produced from x-rays scattered from the
treatment head. This is sometimes called electron
contamination

• Surface dose increases with


• Use of lead trays and blocks – increased electron
contamination
• Field size– increased electron contamination
• Beam’s angle of incidence - increased electron
backscatter and contamination

The Christie NHS


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7. Hand calculation data
1. X-ray beam physics - introduction
2. Electron beam physics - introduction
3. Treatment planning glossary(1)
4. Treatment planning glossary(2)
5. PDD variation
6. Surface dose
7. Hand calculation data
8. Output factors
9. Heterogeneity corrections

The Christie NHS


NHS Foundation Trust
7. Hand calculation data
• Central axis PDDs or
• Isocentric dose data – Tissue (Reference)
Ratios
• TAR, TSR, TPR, TMR

• Calibration factor for standard conditions


• Correction factor for treatment conditions

The Christie NHS


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Correction factors include

To account for difference to reference conditions

• Output factor – scatter changes with area


• Elongation factors, or equivalent area
• Distance factor – inverse square
• Wedge factor – for attenuation in wedge
• Tray factor – for attenuation by a tray

The Christie NHS


NHS Foundation Trust
8. Output factors
1. X-ray beam physics - introduction
2. Electron beam physics - introduction
3. Treatment planning glossary(1)
4. Treatment planning glossary(2)
5. PDD variation
6. Surface dose
7. Hand calculations
8. Output factors
9. Heterogeneity corrections

The Christie NHS


NHS Foundation Trust
Field size correction factor
8. Output Factors
1.2 field size correction factor(C fs ) 
4MV
Dose at d max for a field size( fs)
Dose at d max for a standard field size (10  10)
1.1 20MV

20 MV
1
8 MV
0.9 6 MV
4 MV
0.8
0.0 10.0 20.0 30.0
field size (cm)
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Field Shape Dependence:
Equivalent Square
a
c
2 a b
c
c ab
b

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Field Shape Dependence
3

3 Eq.Sq = 4 x Area / Perimeter


= 4 x (8x6 – 0.5 x 3 x3)
(8+6+5+ (32+32)+3)
= 184 / 26.8 174 / 26.24
8 = 6.63

Eq.sq (Rec) = 2x8x6/(8+6)


= 6.86

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9. Heterogeneity corrections
1. X-ray beam physics - introduction
2. Electron beam physics - introduction
3. Treatment planning glossary(1)
4. Treatment planning glossary(2)
5. PDD variation
6. Surface dose
7. Hand calculations
8. Output factors
9. Heterogeneity corrections

The Christie NHS


NHS Foundation Trust
9. Heterogeneity corrections
Relative Electron Densities

Water 1.0
d1 x re(1) Muscle ~1.1
Lung ~0.3
dt
d2 x re(2) Air Cavities ~0.1
Bone ~1.2-1.5

d3 x re(3)

dwe = S di x re(i)

The Christie NHS


NHS Foundation Trust

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