Académique Documents
Professionnel Documents
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Pharmacokinetics
Syllabus says:
1.1 Pharmacokinetics
1.1.1 absorption
1.1.2 distribution
1.1.3 biotransformation
1.1.5 other
Bryant, Knights and Salerno's Pharmacology for Health Professionals is the new book for 2010
Second sitting which says:
1. Introduction
3. Pharmacokinetics and pharmacodynamics: Rational Dosing and the Time Course of Drug Action
4. Drug Biotransformation)
Amit says:
Definitions – VD, clearance, half life, bioavailability, dosing rate, loading dose
2008-1-3-1 Bioavailability
Syllabus says:
1.2 Pharmacodynamics
1.2.6 other
Amit Says:
Past exam Qs
Syllabus says:
4.1 Neurotransmitter
4.1.2 metabolism
4.1.3 other
4.2.1 sympathetic
4.2.2 parasympathetic
4.2.3 other
Textbook says:
Amit Says:
2009-2-2-5 Amphetamines
2009-1-1-2 Adrenaline
2008-2-2-4 Salbutamol
Syllabus says:
4.4.4 other
Bryant et al say:
15 Anaesthetics
General Anaesthesia
Local Anaesthesis
Amit Says:
2009-2-3-3 Succinylcholine/suxamethonium
2009-2-2-3 Ketamine
2009-2-1-3 Propofol
2009-1-1-2 Adrenaline
Neuro 3
Syllabus says:
4.8.1 benzodiazepines
4.8.2 barbiturates
4.8.3 other
Bryant says:
16 Analgesics
Physiology of pain
pain management
Physiology of sleep
Sleep disorders
Anxiety
Benzodiazepines
Amit Says:
Past Exams...
2010-1-3-3 morphine
2007-2-3-2 clonazepam
2007-1-2-3 midazolam
2005-2-3-3 benzodiazepines
Neuro 4
Syllabus says:
4.5.1 phenothiazines
4.5.2 butyrophenones
4.5.3 atypical
4.5.4 other
4.6 Antidepressives
4.6.1 tricyclics
4.6.3 complex
4.6.4 lithium
4.6.5 other
4.7 Anticonvulsives
4.7.1 phenytoin
4.7.2 carbamezepine
4.7.3 valproate
4.7.4 other
18 Antiepileptic Drugs
19 Psychotropic Agents
Amit says:
What is PK of lithium?
Exams...
2009-1-2-3 Chlorpromazine
2009-1-1-3 Carbemazepine
2008-2-3-3 Phenytoin
2008-2-2-3 SSRI
2008-2-1-3 TCAs
Syllabus says:
3. Cardiovascular System
3.1.2 inotropes
Vasopressin,
Amit says:
Learn PK of Amiodarone
Exams say:
2010-1-1-4 Amiodarone
2010-1-2-4 Metoprolol
2010-1-3-4 Atropine
2009-2-1-4 tPA
2009-1-1-2 Adrenaline
2009-1-2-2 Digoxin
2008-2-3-5 flecainide
2008-1-3-2 nitrates
2008-1-1-4 atropine
Syllabus says:
3.2.1 nitrates
3.2.4 other
Amit says:
Describe the main features of B-Blockers and list different types, and the types of blockade that they
cause
Learn PK of Amiodarone
Syllabus says:
3.5 Antihypertensives
3.5.3 vasodilators
3.5.4 sympatholytics
3.5.5 other
3.6 Diuretics
3.6.1 loop diuretics
3.6.3 other
Bryant et al says:
Management of Hypertension
Amit says:
Describe the main features of B-Blockers and list different types, and the types of blockade that they
cause
2006-1-2-2 ß blockers
Syllabus says:
3.7.1 streptokinase
3.7.3 Abciximab
3.7.4 ticlopidine
3.7.5 aspirin
3.7.7 other
Anticoagulants
Thrombolytics
Antiplatelet drugs
Amit says:
Exams prove:
2009-2-2-4 Warfarin
2009-2-1-4 tPA
2007-2-3-3 Aspirin
2007-1-1-4 tPA
2006-2-2-4 Clopidogrel
Respiratory Pharmacology
Syllabus says:
2. Respiratory System
2.1 Methylxanthines
2.2 Sympathomimetics
2.5 Antitussives
2.6 Oxygen
2.8 Other
Amit Says:
Exams reveal that thes focussed topics don't get 'hit' terribly often, and that the syllabus weighting
is not too relevant to the exam.
2008-2-2-4 Salbutamol
2008-1-2-5 Methylxanthines
2006-2-2-3 Dexamethasone
antimicrobial 1
Syllabus:
5. Antimicrobial Agents
5.3 Aminoglyocides
5.4 Sulphonamides
5.5 Quinolones
5.7 Miscellaneous
Bryant, Knights, Salerno
51 Antibacterial drugs
Miscellaneous antibiotics
Erythromycin vs azithromycin
What pathogens do the macrolides target
Past VIVAs:
2009-1-1-4 Macrolides
2009-1-3-4 (Acyclovir)
2008-2-1-2 Metronidazole
2008-2-2-2 Cephalosporins
2008-2-3-2 Gentamicin
2008-1-3-4 beta-Lactams
2007-1-1-3 Gentamicin
2007-1-3-4 Chloromycetin
2006-2-1-4 Penicillin
2006-2-3-4 Trimethoprim
Annoying nit-picking:
Aminoglycosides that are derived from bacteria of the Streptomyces genus are named with the suffix
-mycin, whereas those that are derived from Micromonospora are named with the suffix -micin.
Streptomycetes produce over two-thirds of the clinically useful antibiotics of natural origin (e.g.,
neomycin, chloramphenicol).[
Cephalosporin compounds were first isolated from cultures of Cephalosporium acremonium from a
sewer in Sardinia in 1948 by Italian scientist Giuseppe Brotzu [2].
Syllabus says:
5. Antimicrobial Agents
5.3 Aminoglyocides
5.4 Sulphonamides
5.5 Quinolones
5.7 Miscellaneous
5.8 Antifungal
5.10 Disinfectants
5.14 Other
Amits 2 cents...
Bryant et al
Exams...
2009-1-3-4 Acyclovir
Syllabus says:
Bryant et al...
Oral contraceptives
Past exams...
*analgesics + anti-inflammatories
*autacoids
Endocrine Pharmacology
Syllabus says:
7. Endocrine System
7.2 Steroids
7.7 Other
Bryant et al:
Amit's contribution:
2008-2-2-5 Thioamides
2008-2-1-4 Sulfonylureas
2008-1-1-5 (Octreotide)
2006-2-2-3 Dexamethasone
2005-2-1-5 Glucagon
Gatrointestinal Pharmacology
Syllabus says:
8. Gastro-Intestinal Tract
8.1 Antiemetics
8.2 Antidiarrhoeal
8.3 Laxatives
8.5 Antispasmodics
8.7 Other
Bryant says:
Amit's 2 cents:
Past exams:
2009-1-3-3 Ondansetron
2009-1-2-3 Chlorpromazine
2008-2-3-4 Metoclopramide
2008-2-1-5 Laxatives
2008-1-1-5 Octreotide
Toxicology
Syllabus says:
10. Toxicology
10.1.1 emetics
10.1.2 adsorbants
10.2 Overdose
10.7.1 paracetamol
10.7.2 organophosphates
10.7.3 carbon monoxide
10.7.4 cyanide
Bryant says:
Amit says:
Paracetamol
Opiate
Benzodiazepine
TCA
Anti depressants
Use of charcoal
Past exams: (keeping in mind that many questions have a "toxic level" sub-question)
2009-2-2-5 amphetamines
2008-2-1-3 TCAs
2007-2-3-5 dantrolene
Syllabus says:
Bryant says:
Pregnancy
Lactation
children
elderly
Amit, too:
Past exams:
Past Topics
3.beta Lactams
4.Antiemetics
amines - pp 552
SEPTEMBER 2008
Group 1
2.Metronidazole
3.Tricyclic Antidepressants
4.Sulfonylureas
5.Laxatives
Group 2
2.Cephalosporins
3.SSRIs
4.Salbutamol
5.Thioamides
Group 3
2.Gentamicin
3.Phenytoin
4.Metaclopramide
5.Flecainide
APRIL 2009
Group 1
1.Volume of Distribution
2.Adrenaline
3.Carbamazepine
4.Macrolides
Group 2
1.Drug Half Life
2.Digoxin
3.Chlorpromazine
5.Prescribing in Pregnancy
Group 3
2.Classes of Anti-hypertensives
3.Ondansetron
4.Acyclovir
5.Prescribing in Children
SEPTEMBER 2009
Group 1
1.Drug biotransformation
3.Propofol
4.tPA
5.Activated charcoal
Group 2
1.Dose response
mellitus
3.Ketamine
4.Warfarin
5.Amphetamines
Group 3
1.Drug clearance
2.Side effects of NSAID
3.Succinylcholine / Suxamethonium
5.Topical anaesthetics