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HCG - Human chorionic gonadotropin: 80% Unique Content

General Information:

Drug name: human chorionic gonadotropin (HCG)


Drug class: Glykoproteinhormon
Common brand names: Primogonyl, HCG, Pregnyl, Provigil
Common drug quantity: Injections: 500 I.U., 1500 I.U., 5000 I.U.

Use and effective range:


Applications: Post-Cycle-Therapy
Anabolic components: low
Androgenic component: low

Duration of use:
Application period: 2-3 weeks

Active-Life: 64 hours
Drug Class: Luteinizing Hormone (LH) - Gonadotropin
Average Reported Dosage: Men 2000-5000 i.u. injected every 5th day
Acne: Yes
Water Retention: Yes, HCG is a female hormone.
Liver Toxic: None
Aromatization: None, however due to HCG use testosterone levels increased and aromatize was
a potential side effect

HCG is used medically to positively influence ovulation in women, and to help produce estrogen.
It is also utilized in fertility medicine to aid in ovulation.

Male bodybuilders used HCG for another important reason. HCG is almost exactly the same
amino acid sequence as Luteinizing Hormone (LH). LH is normally produced in the pituitary gland
which is then circulated to the testes where it contacts the Leydig cells, which then produce
androgens such as testosterone. According to some clinical studies this works so well that an
injection of 1500-2000 i.u. of HCG has increased plasma testosterone levels 200-300% over
normal levels. For the males who utilized high aromatizing AAS, HCG was a "partial" cure for
restarting natural testosterone production either mid or post-cycles.

When administering exogenous androgens as AAS, the body's endocrine system shuts down
partially or completely natural androgen production in an attempt to maintain homeostasis. That is
because the hypothalamus senses the excess estrogens from AAS aromatization and signals the
pituitary to partially or completely stop producing LH and FSH. Since the Leydig cells in the testes
do not receive the signal from LH, they shut down testosterone production partially or completely.
Also reduced is the sperm production as a result of FSH down-regulation. Since the testes are
not producing androgens and/or sperm at their normal level, the testes shrink. That often causes
a drop in libido too. A lot of AAS users reported sexual dysfunction for a brief period post-cycle.
HCG injections act as a replacement for the LH produced normally by the pituitary gland which
stimulates androgen and sperm production by the testes. If 2000-5000 i.u. of HCG is injected
every 5th day for 2-3 weeks, mid or post-cycle, the testes begin to function again. An increase in
total testosterone is realized and athletes often made some of their best gains at this point. When
HCG was administered beginning the last week of an AAS cycle and for an additional 1-2 weeks
post-cycle, the testes function normalized again and much of the common post- AAS cycle
muscle mass and strength loss was avoided. HCG only replaces natural LH. The pituitary and
hypothalamus part of the HPTA still sense no reason to produce gonadotropins and restore
normal LH/FSH production. Thus ending HCG administration sometimes only brought on another
crash. Staying on HCG for more than 3 weeks without at least a month off between HCG cycles
could cause permanent gonadal dysfunction and/or a desensitizing of Leydig Cells. Males
commonly used Clomid or Cyclofenil with HCG. Available literature shows that Clomid stimulates
the pituitary to release more gonadotropin so a quicker and elevated level of LH and FSH are
realized. When following an AAS cycle with 2000-5000 i.u. HCG every 5th day for 2-3 weeks and
ingesting Clomid for the last 10-15 days of HCG administration many athletes noted that muscle
mass and strength losses post AAS cycle were significantly avoided. Some athletes also used
Clenbuterol at this point.