Intracranial/Spinal tumors:

1. A young boy is brought to the clinic complaining of not being able to see as well as he used
to. Visual field examination reveals a bi-temporal hemianopsia. You suspect a tumor located
near the:
A. Pituitary gland and stalk
B. Calcarine sulcus
C. Parieto-occipital sulcus
D. Nucleus of cranial nerve III

2. An MRI reveals a large tumor occupying much of the left parietal lobe of a middle aged female
patient. It is also the most common kind of intracranial tumor with typically a poor
prognosis. Such tumors are called:
A. Schwannomas
B. Oligodendrogliomas
C. Meningiomas
D. Astrocytomas

3. A patient presents unilateral tinnitus and unilateral hearing loss. On physical examination,
there is discrete facial weakness and loss of corneal reflex on the same side as the symptoms.
Where is the most likely anatomic location to produce the signs and symptoms in this patient?
A. Frontal cortex
B. Anterior pituitary
C. Anterior horn of upper spinal cord
D. Cerebellopontine angle

4. Pathomorphologic criteria for diagnosis of meningioma are:

A. Well circumscribed nodule, whorls of spindle-shaped cells, and psammoma bodies.
B. Cyst with mural nodule, pilocytic astrocytes with Rosenthal fibers.
C. Well circumscribed nodule, “fried-egg” cells, and chicken-wire capillary pattern.
D. Pleomorphic glial cells, high mitotic activity, pseudopalisading, and vascular endothelial
proliferation.

5. Which of the following criteria are used for the diagnosis of oligodendroglioma?
A. Pleomorphic glial cells, high mitotic activity, pseudopalisading, and vascular endothelial
proliferation
B. Cyst with mural nodule, pilocytic astrocytes with Rosenthal fibers
C. Well circumscribed nodule, whorls of spindle-shaped cells, and psammoma bodies
D. Well circumscribed nodule, “fried-egg” cells, and chicken-wire capillary pattern

6. What finding distinguishes glioblastoma multiforme from lower grade astrocytomas?

A. Mitoses
B. Cellular density
C. Necrosis
D. Marked anaplasia (giant cells)
7. Which of the following lesions extends across the corpus callosum?

A. Glioblastoma
B. Cerebral lymphoma
C. Schilder's disease
D. All of the above

8. The most common intracranial site of germ cell tumors is:

A.The pineal gland

B.The pituitary gland
C.The hypothalamus
D.The midline of the cerebellum

9. Which of the following may present as a ring enhancing lesion?

A.Acute multiple sclerosis plaques

B.Metastatic tumors
C.Glioblastoma
D.All of the above

10. Which of the following statements about meningiomas is not true?

A. It is more common in women

B.The tumor is attached to the dura
C.Deletion of chromosome 22 is frequent
D.Brain invasion is frequent