BS-300/BS-320 Chemistry Analyzer

Service Manual

© 2011 Shenzhen Mindray Bio-medical Electronics Co., Ltd. All rights Reserved. For this
Service Manual, the issued Date is 2011-09 (Version: 1.0).

Intellectual Property Statement

SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (hereinafter called

Mindray) owns the intellectual property rights to this Mindray product and this manual. This
manual may refer to information protected by copyrights or patents and does not convey any
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Responsibility on the Manufacturer Party

Contents of this manual are subject to changes without prior notice.

All information contained in this manual is believed to be correct. Mindray shall not be liable
for errors contained herein nor for incidental or consequential damages in connection with the
furnishing, performance, or use of this manual.
Mindray is responsible for safety, reliability and performance of this product only in the
condition that:

 all installation operations, expansions, changes, modifications and repairs of this

product are conducted by Mindray authorized personnel;
 the electrical installation of the relevant room complies with the applicable national
and local requirements;
 the product is used in accordance with the instructions for use.

Upon request, Mindray may provide, with compensation, necessary circuit diagrams,
calibration illustration list and other information to help qualified technician to maintain and
repair some parts, which Mindray may define as user serviceable.

WARNING:

It is important for the hospital or organization that employs this equipment to carry out a
reasonable service/maintenance plan.

Neglect of this may result in machine breakdown or injury of human health.

NOTE:

This equipment is to be operated only by medical professionals trained and authorized by

Mindray or Mindray-authorized distributors.

Warranty

THIS WARRANTY IS EXCLUSIVE AND IS IN LIEU OF ALL OTHER WARRANTIES,

EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR
FITNESS FOR ANY PARTICULAR PURPOSE.

Exemptions

Mindray's obligation or liability under this warranty does not include any transportation or
other charges or liability for direct, indirect or consequential damages or delay resulting from
the improper use or application of the product or the use of parts or accessories not approved
by Mindray or repairs by people other than Mindray authorized personnel.

This warranty shall not extend to:

  any Mindray product which has been subjected to misuse, negligence or accident;
 any Mindray product from which Mindray's original serial number tag or product
identification markings have been altered or removed;
 any product of any other manufacturer.

Return Policy

Return Procedure

In the event that it becomes necessary to return this product or part of this product to Mindray,
the following procedure should be followed:

 Obtain return authorization: Contact the Mindray Service Department and obtain a
Customer Service Authorization (Mindray) number. The Mindray number must appear on
the outside of the shipping container. Returned shipments will not be accepted if the
Mindray number is not clearly visible. Please provide the model number, serial number,
and a brief description of the reason for return.
 Freight policy: The customer is responsible for freight charges when this product is
shipped to Mindray for service (this includes customs charges).
 Return address: Please send the part(s) or equipment to the address offered by Customer
Service department.

Company Contact

Manufacturer: Shenzhen Mindray Bio-Medical Electronics Co., Ltd.

Address: Mindray Building, Keji 12th Road South, Hi-tech Industrial Park, Nanshan,
ShenZhen 518057, P.R.China,

Tel: +86 755 26582479 26582888

Fax: +86 755 26582934 26582500

Preface

Who Should Read This Manual

This manual is written for service professionals authorized by Mindray.

Conventions Used in This Manual

Safety Symbols

In this manual, the signal words BIOHAZARD, WARNING, CAUTION And NOTE are
used regarding safety and other important instructions. The signal words and their meanings
are defined as follows. Please understand their meanings clearly before reading this manual.

When you see … Then …

WARNING:

Read the statement following the symbol. The statement is alerting you to an operating hazard
that can cause personal injury.

BIOHAZARD:

Read the statement following the symbol. The statement is alerting you to a potentially
biohazardous condition.

CAUTION:

Read the statement following the symbol. The statement is alerting you to a possibility of
system damage or unreliable results.

NOTE:

Read the statement following the symbol. The statement is alerting you to information that
requires your attention.

Graphics

All graphics, including screens and printout, are for illustration purpose only and must not be
used for any other purposes.
EC Representative

Name: Shanghai International Holding Corp. GmbH (Europe)

Address: Eiffestraβe 80, Hamburg 20537, Germany

Tel: 0049-40-2513175

Fax: 0049-40-255726
 Contents

1 Specification ................................................................................................................ 1-1

1.1 System Feature........................................................................................................... 1-1

1.2 Loading System Feature............................................................................................ 1-1

1.3 Analysis System Feature............................................................................................ 1-2

1.4 Others ........................................................................................................................ 1-2

2 System Installation ...................................................................................................... 2-1

2.1 Check before Installation ........................................................................................... 2-1

2.2 Installation Procedure............................................................................................... 2-1

3 System Descriptions..................................................................................................... 3-1

3.1 Dispensing System..................................................................................................... 3-2

3.1.1 Probe assemblies ...................................................................................................... 3-3

3.1.2 Disk assemblies........................................................................................................ 3-3

3.2 Feeder ........................................................................................................................ 3-5

3.2.1 Feeder assemblies ..................................................................................................... 3-5

3.2.2 Manipulator .............................................................................................................. 3-6

3.3 Temperature Control System ...................................................................................... 3-7

3.3.1 Temperature control assembly .................................................................................. 3-7

3.3.2 Reagent preheating ................................................................................................... 3-8

3.3.3 Reagent refrigeration ................................................................................................ 3-8

3.4 Photometric System ................................................................................................... 3-9

3.5 Fluid System.............................................................................................................. 3-9

3.6 ISE Module (optional) ............................................................................................. 3-11

4 Functions of Boards..................................................................................................... 4-1

4.1 Main Control Board ................................................................................................... 4-1

4.2 Power Drive Board .................................................................................................... 4-2

4.3 A/D Conversion Board............................................................................................... 4-2

4.4 Reagent Refrigeration Board ..................................................................................... 4-2

4.5 Level Detection Boards .............................................................................................. 4-3

4.6 Feeder Connection Board .......................................................................................... 4-3

4.7 Manipulator Connection Board ................................................................................. 4-3

4.8 Probes Connection Board .......................................................................................... 4-4

4.9 Power Supply Assembly ............................................................................................. 4-4

5 Maintenance and Service............................................................................................ 5-1

5.1 Replacing Lamp ......................................................................................................... 5-1

5.2 Replacing Light Filter Assembly................................................................................ 5-3

5.3 Replacing Optical Fiber............................................................................................ 5-6

5.4 Adjusting Reaction Disk, Manipulator and Feeder ................................................. 5-10

5.5 Adjusting Probes and Disks ..................................................................................... 5-11

5.6 Replacing the filter assembly................................................................................... 5-13

5.7 Replacing Components of ISE Unit (optional) ........................................................ 5-14

5.7.1 Replacing Tubing ................................................................................................... 5-14

5.7.2 Replacing Pumps .................................................................................................... 5-18

5.7.3 Replacing ISE Module ........................................................................................... 5-18

6 Software Introduction ................................................................................................. 6-1

6.1 System Software ......................................................................................................... 6-1

6.1.1 System initialization ................................................................................................. 6-1

6.1.2 Shutdown processing ................................................................................................ 6-2

6.2 Control Software........................................................................................................ 6-2

7 Service Flow................................................................................................................. 7-1

7.1 Fluid Level Detection Failure of Reagent Probe ....................................................... 7-1

7.2 Fluid Level Detection Failure of Sample Probe ........................................................ 7-2

7.3 Liquid Dropping from Probes .................................................................................... 7-3

7.4 Failing to Detect Level of Water for Washing Exteriors ............................................ 7-4

7.5 Abnormal Results ....................................................................................................... 7-5

7.5.1 All Results Being Abnormal ..................................................................................... 7-5

7.5.2 Some Results Being Abnormal ................................................................................. 7-5

7.5.3 Several Results Being Abnormal .............................................................................. 7-6

7.6 Insufficient Light Intensity of Lamp ........................................................................... 7-7

7.7 Temperature Control Failure ..................................................................................... 7-8

7.8 Bar Code Scanner (optional) Failure ........................................................................ 7-9

7.9 Feeder Failure ......................................................................................................... 7-11

7.9.1Transducer Distribution of the Feeder .................................................................... 7-11

7.9.2 Feeder Failure ......................................................................................................... 7-12

7.9.3 Manipulator Failure ................................................................................................ 7-13

7.10 Troubleshooting of ISE Unit (optional) ................................................................... 7-13

8 Mechanical Structure.................................................................................................. 8-1

9 Maintenance and Test Software .................................................................................. 9-1

9.1 General ...................................................................................................................... 9-1

9.2 Command ................................................................................................................... 9-3

9.2.1 Single Command Area .............................................................................................. 9-3

9.2.2 Macroinstruction Area............................................................................................ 9-10

9.3 PARA and Speed ...................................................................................................... 9-14

9.4 Temperature ............................................................................................................. 9-19

9.5 Photoelectric ............................................................................................................ 9-20

1 Specifications

1.1 System Feature

 Dimension: 980mm × 710mm × 1200mm (W × D × H)

 Weight: 186kg
 Power supply: AC100-130V ± 10% or 200-240V ± 10%
 Input power: 1000VA
 System: optional, multi-channel, multi-test
 Scope: Clinical chemistries
 Test types: end-point, kinetic and fixed-time. All support double-reagent and double-
wavelength
 Calibration type: Linear (single-point, two-point and multi-point), Logistic 4P, Logistic
5P, Exponential 5P, Polynominal 5P, Parabola, Spline
 QC rules: Westgard multi-rule, X -R, Cumulative sum check, Cumulative error, Twin-plot
 Tests analyzed simultaneously: 48 (single-reagent) / 24 (double-reagent); if the ISE unit
(optional) is connected, 3 (Na, K and Cl included) or 3 (Na, K and Cl included) tests are
added
 Throughput: maximum 300tests/h; if the ISE (optional) is connected, maximum 420tests/h
(Na, K and Cl included)

1.2 Loading System Feature

 Sample volume: 2µl~45µl; Precision: 0.1µl; for the ISE (optional), 70µl serum, 70µl
plasma, 140µl diluted urine
 Sample disk: general sample disk, including the inner circle and the outer circle
 Sample tube position: 60 positions, including 6 calibrator positions, 3 control positions, 5
for STAT sample positions; 5 virtual disks for maximum 300 samples
 Sample probe: with a built-in level detector; equipped with auto safeguard; capable of
tracking sample level
 Washing function: automatically washing interior and exterior of sample probe; carryover
no more than 0.1%
 Pre-dilution: 3≤ dilution rate ≤ 225, taking reaction cuvettes as the container
 Reagent volume: 10-450ul; Precision: 1ul
 Reagent disk: including the inner circle and the outer circle
 Reagent position number: 25/50 reagent positions. Each reagent position is available for
containing one Hitachi 7060 bottle, one Hitachi 7170 bottle, one Mindray Outer-circle
20mL bottle, one Mindray Inner-circle 40mL bottle, one Mindray Outer-circle 40mL
bottle or one Mindray Outer-circle 62mL bottle
 Reagent probe: One independent probe which has a built-in level detector; is equipped
with auto safeguard and capable of tracking reagent level
 Washing function: automatically washing interiors and exteriors of reagent probes;
carryover no more than 0.1%
 Mixing bar: for single-reagent tests, it functions after sample dispensing; for double-
reagent tests, it functions after the dispensing of the sample and the second reagent.

1.3 Analysis System Feature

 Lamp house: 20w lamp

 Light splitting mode: Splitting by optical fiber, filtering by an interference filter.
 Half band-width: 10±2nm
 Wavelength: 340, 405, 450, 510, 546, 578, 630, 670, 700nm or 800nm (optional)
 Absorbance range: -0.1~5, 10mm optical path conversion
 Reaction cuvette: 5 × 6 × 25mm, optical path 5mm. Material: PS, disposable. Volume:
750uL
 Reaction liquid volume: 150-500µl
 Max. reaction time: 20 minutes
 Reaction temperature: 37±0.3℃ with fluctuation of ±0.1℃

1.4 Others

 Operating system: Windows XP or Windows 7 Home 32 bits.

 Display: optional
 System interface: RS-232C
 Printer: optional
 Built-in bar code scanner: optional
 ISE module: optional
2 System Installation

NOTE:

The analyzer should be installed or moved to another place by Mindray-authorized personnel

only.

2.1 Check before Installation

The user should provide the environment that meets the requirements mentioned in the
Operation Manual. Check if the environment meets the requirements before installing the
analyzer. Refer to the chapter 2 of the Operation Manual for details.

2.2 Installation Procedure

1 Ensure available installation fields and environments in hospitals.

2 Confirm the reagents and calibrators.

3 Go to the installation field, and then check the delivery list for acceptance.

4 Install the four handles on the four angles of the analyzer. Move the analyzer to the
installation field, fix the casters, and then remove the handles.

5 Install the computer, display and printer.

6 Open the front plate, and check whether cable connections are loose. Open the top
plate, check whether the probe assemblies, reagent disk and sample disk are intact and
in good performance.

7 Connect the communication cable, power cable, grounding wire, waste tank and
deionized water tank. Install the used-cuvette bucket, reagent probe, sample probe and
mixing bar.

8 Top up the deionized water tank with deionized water.

9 Use syringe to inject water into the filter, and connect filter to the cap assembly of
the DI water tank.

10 Put reaction cuvettes in the feeder. Remember to check whether the surfaces of the
cuvettes are smooth. In case of any bump, remove it before loading the cuvette to the
 compartment. Do not touch the light transmission part of the cuvette in which the
colorimetric reading is taken.

11 Load acid and alkaline detergents to positions 46 and 47, and distilled water to
positions 49 on the reagent disk. Load distilled water to position 60 on the sample
disk.

12 Switch on the analyzer as follows: POWER → ANALYZING UNIT POWER →

display → computer → printer.

13 After Windows is started, double-click the icon of BS-300/BS-320 on the desktop

to start the system software. The system program will automatically finish the self-test,
become online and warm up the reaction cuvettes within about 30 minutes.

14 Select the [System/Status] menu, and then observe the system status and record it
in the table below:
Feeder status Unconnected Full Half full Empty

Reaction disk
temperature

Reagent disk
temperature

Ambient temperature

Waste tank status Abnormal (full) Normal (not full)

Detergent status Abnormal (empty) Normal (available

Printer status No printer Normal

Main control u Unconnected Idle Running

Reaction disk unit Unconnected

Reagent disk unit Unconnected

Sample disk unit Unconnected

Loading/unloading unit Unconnected

Temperature control Unconnected

unit

Lamp

Network connection Unconnected

Wavelength Dark current Light source

340

405

450

510

546

578

630

670

700
 15 Select the [System/Maintenance] menu. Then select theMotiontab page, and
implement all sub-steps of each unit to see whether they are normal. In case of any
exception, adjust it.

16 Wash the interiors and exteriors of the sample probe, reagent probe and mixing bar
for several times to make the fluid circuit filled.

17 Set parameters for test, reagent and calibration under the Parameters menu

18 Request for calibration and samples, run and then debug the results.

19 After debugging the results, fill them in the table below

Test ALT CREA BUN

Target value

2sd range

Test value 1

Test value 2

Test value 3

Test value 4

Test value 5

Test value 6

Test value 7

Test value 8

Test value 9

Test value 10

20 Training

Can the user complete daily tests? Yes□ No□

Is the user familiar with the analytical methods such as kinetic, two-point, endpoint?
Yes □ No □
Is the user familiar with the daily, weekly and monthly maintenance and relevant
maintenance methods? Yes □ No □

Is the user skilled in washing dust screens? Yes □ No □

Is the user skilled in cleaning and replacing the probes and the mixing bar? Yes □ No □

Is the user skilled in replacing the plunger assemblies of syringes? Yes □ No □

Is the user familiar with replacing the filter? Yes □ No □

Is the user skilled in replacing the lamp? Yes □ No □

Is the user skilled in maintenance of built-in bar code scanner? Yes □ No □

Is the user skilled in maintenance of ISE unit? Yes □ No □

Does the user know the positions, roles and preparation methods of distilled water and acid
and alkaline detergents? Yes □ No □

3 System Descriptions

The BS-300/BS320 analyzer consists of the analyzing unit, operation unit and output unit.

The analyzing unit consists of the dispensing system, feeder, temperature control system,
photometric system and fluid system.

Figure 3-1 Overview of the analyzing unit and the operation unit
3.1 Dispensing System

The dispensing system consists of the probe assemblies (including the reagent probe
assembly, sample probe assembly and mixing bar assembly), reagent disk, sample disk and
reaction disk

3.1.1Probe assemblies

Among the probe assemblies, the mixing bar assembly is the same as the reagent
probe assembly and the sample probe assembly, except that the knurled axis is 30mm shorter
3.1.2 Disk assemblies

The three disk assemblies are different in their coders. The coder corresponds to the position
where disks should stop. There is an initial-position mark under every coder. The three coders
of the three disks have three coder transducers. Each transducer has two photoelectric
switches for inducing the rotation and initial position of the disk.

The step motors control the disk assemblies, and the synchronizing belts serve as the gearing.
There is a build-in bar code scanner to the left of the sample disk. The scanner is optional
3.2Feeder

The feeder consists of the feeder assemblies and the manipulator. It is designated to send cuvette
segments to the reaction disk, take out the used ones and abandon them to the used-cuvette bucket.

3.2.1Feeder assemblies

The feeder assemblies include the gearing assembly, cuvette compartment assembly, cuvette-pushing
assembly and no-cuvette detection assembly (see the following figure). The supporting plate of the
feeder assemblies is a square piece of steel that is connected to the analyzing unit by its four poles,
which are secured by four nuts. Unscrewing the nuts, you can disassemble the feeder assemblies from
the analyzing unit easily
The feeder assemblies include the gearing assembly, cuvette compartment assembly, cuvette-
pushing assembly and no-cuvette detection assembly (see the following figure). The
supporting plate of the feeder assemblies is a square piece of steel that is connected to the
analyzing unit by its four poles, which are secured by four nuts. Unscrewing the nuts, you can
disassemble the feeder assemblies from the analyzing unit easily. There are five transducers
that are shown in the figure below.

The no-cuvette transducer is used to detect whether there is a cuvette segment at the loading
position. The insufficient-cuvette transducer is used for determine whether there are less than
10 reaction cuvettes in the compartment or not. If yes, the analyzer will give a prompt.

3.2.2Manipulator

Two step motors (horizontal and vertical) supply power for horizontal and vertical
movements of the manipulator.

The upper finger and lower finger are same in their structures. They work together to replace
used cuvette segments with new ones.

The manipulator runs in a relatively complicated way. There are four transducers on it:
vertical transducer, horizontal transducer and two finger transducers.
3.3Temperature Control System

3.3.1 Temperature control assembly

The temperature control assembly of the reaction disk consists of the temperature-controlled
pot, dummy plate, outer heat insulator, inner heat insulator, bottom heat insulator, cover board
sponge, cover board, press plate, top heater, reaction disk/cuvettes, photoelectric seat,
temperature transducer, fans, and control circuit.
1: Temperature transducer and bracket

2: Fans

3: Photoelectric seat

4: Outer heat insulator

5: Cover board

6: Top heater

7: Press plate

8: Cover board sponge

9: Temperature-controlled pot

10: Bottom heater

11: Bottom heat insulator

12: Inner heat insulator

13: Dummy plate

Upper heater: square in shape, 220/110VAC, 125W

Lower heater: ring in shape, 220/110VAC, 350W

Total power: 475W.

The function of heaters is to compensate the heat for incubating the reagent and for
maintaining the temperature of the temperature-controlled chamber.
Fans are used in series in the temperature-controlled chamber. It makes the air circulating in
the chamber, and enhances the convective heat exchange. There are four fans in the chamber.
All have the alarm function.

The temperature transducer feeds back the air temperature at the position several millimeters
from the bottom of the reaction cuvette.

The overheat protection switch is to switch off the power when the temperature controller
does work and the temperature-controlled chamber reaches 55℃, so as to avoid overheat or
fire. When the temperature-controlled chamber becomes 35℃, this switch will automatically
be reset

3.3.2 Reagent preheating

The preheating assembly consists of two aluminum plates, a Teflon tube having nine loop
sections, heating components, transducer, temperature protection switch, thermal conductive
colloid, a section of tube and the reagent probe.

The temperature of the thermal source of the preheater is controlled at 45℃. The initial
temperature of the reagent is 2 ~ 10℃ when it is taken out of the refrigeration chamber. When
the reagent passes the heater, its temperature increases to 35℃. Then the reagent is added into
the reaction cuvette and the preheating process is finished

3.3.3 Reagent refrigeration

The refrigeration module consists of refrigeration cabin, PU heat-insulating sheath, reagent

disk, reagent bottle, temperature transducer, refrigeration flakes, heat sinking component, fan
and control circuit. The refrigeration module is shown in the following figure
The refrigeration assembly consists of fan, hot-end radiator, POM connector, cold-end heat-
conductive aluminum block, and PELTIER refrigeration flake. Each analyzer has two such
refrigeration assemblies, as shown in the figure below. The cold-side of the refrigeration flake
clings to the refrigeration compartment, and the hot-side clings to the radiator (The side
having letters should cling to the refrigeration aluminum block).

Each refrigeration flake corresponds to a heat-sinking block and a cooling fan. It should be
installed with the cold side upward

3.4 Photometric System

The measurement photometric system provides 9 monochromatic lights to measure the

absorbance of the reacting liquid in the rotating reaction cuvettes.

3.5 Fluid System

The fluid system is shown in the following figure

As shown in the figure above, the fluid system consists of interior washing and exterior
washing.

The syringe assembly controls the aspiration volume by controlling the travel of the
sample/reagent syringe. It is the core part of the fluid system
3.6 ISE Module (optional)

The ISE module that is used to measure the concentration of K+, Na+, Cl-and Li+in serum,
plasma and urine consists of ion-selective electrodes, peristaltic pumps and calibrants

4 Functions of Boards

The analyzer is integrated with the following boards:

 Main control board

 Power drive board
 Sample level detection board
 Reagent level detection board
 A/D conversion board
 Nine photoelectric conversion boards (340nm, 405nm, 450nm, 510nm, 546nm,
578nm, 630nm, 670nm, 700nm)
 Reagent refrigeration board
 Power supply assembly
 Manipulator connection board
 Feeder connection board
 Probes connection board
4.1 Main Control Board

The main control board is the control center of the whole hardware system. It consists of the
control circuits of 6 functional units (including main control unit, photoelectric unit, reagent
unit, sample unit, loading/mixing unit, temperature control unit). Each functional unit has an
MCU. They communicate in the multi-unit mode and thus compose the whole control system.

The functions of the main control board are:

 communicating with the PC through the RS232, receiving and analyzing instructions
from the PC and sending data to the PC.
 controlling photoelectric conversion through the interface with the A/D conversion
board, reading and saving data from the A/D conversion board.
 outputting control signals of each unit through the interface with the power drive
board.
 receiving signals of fluid level detection and bump collision through the interface with
the level detection boards.
 detecting signals from temperature transducers and controlling temperature of the
reaction disk and reagent preheating.
 receiving signals from position transducers, deionized water transducer and waste
transducer and controlling the transducers.
 controlling the built-in sample bar code scanner, reading the data and sending it to the
PC.
 controlling the ISE module, reading the results and sending them to the PC

4.2 Power Drive Board

 The main functions of the power drive board are to receive the control signals from the
main control board and control drive components. The block diagram of the power
drive board is shown in the figure below.
4.3 A/D Conversion Board

The 9 photoelectric conversion circuits convert the intensity signals of the lights transmitting
through the reaction cuvettes to electric signals, and then transmit them to the A/D conversion
board through a 5-core shielded cable. Photoelectric conversion boards for different
wavelengths have different gains and cannot be replaced by each other.

The A/D conversion board filters and amplifies the 9 channels of electric signals output from
the photoelectric conversion boards, transmits them through the multi-way gating switch to
the A/D converter and then sends them to the main control board for further processing

4.4 Reagent Refrigeration Board

The circuits of the reagent refrigeration board include the refrigeration circuit and the fan
circuit.

The refrigeration circuit is needed to work continuously, so it is powered separately.

The control objects of the reagent refrigeration board include: Reagent refrigeration: 2
PELTIER components, 4 fans

Heat sink system for the whole device: 3 lamp-cooling fans, 4 temperature control fans of the
reaction disk.

4.5 Level Detection Boards

The level detection boards that include sample level detection board and reagent level
detection board are used to detect the fluid level of sample and reagent separately. When the
analyzer aspirates reagents/samples, the probes dip into the liquid to a specific depth, so as to
avoid carryovers that have impacts on test results, and to avoid air aspiration when the
reagent/sample is insufficient.

4.6 Feeder Connection Board

The feeder connection board transfers the signals between the feeder transducer and the main
control board, and connects the power drive board and the loading motor (DC). Connections:
 Connector Connected with

J 91 Front transducer

J 92 Back transducer

J 93 Intermediate transducer

J 94 No-cuvette transducer

J 95 Pressure transducer

J 96 Motor control wire (connected with the power drive board)

J 97 Motor control wire (connected the motors)

J 98 Cuvette-loading button

J 99 Connection wire of the main control board

4.7 Manipulator Connection Board

The manipulator connection board transfers the signals between the manipulator
transducer and the main control board, and connects the power drive board and the
electromagnet.

Connections:

Connector Connected with

J 101 Horizontal loading position transducer

J 102 Vertical loading position transducer

J 103 Electromagnet-closing transducer of the lower

hand
 Connector Connected with

J 108 Electromagnet-closing transducer of the upper

hand

J 104 Drive wire of the electromagnet of the upper hand

J 105 Drive wire of the electromagnet of the lower hand

J 106 Drive wire of the electromagnet (connected with

the power drive board)

J 107 Connection wire of the main control board

J 109 Safeguard transducer (reserved)

J 110 Safeguard transducer (reserved)

4.8 Probes Connection Board

The probes connection board transfers the signals between the sample/reagent level detection
board and the main control board, inputs the temperature signals, outputs the reagent
preheating signals, and transfers the signals between the power drive board and the mixing
motor (DC)

Connector Connected with

J 200 Interface of the sample level detection board

J 201 Interface of the reagent level detection board

J 202 nterface of the mixing motor (DC)

J 203 Sample detection signal interface of the main control

board

J 204 Reagent detection signal interface of the main control

board

J 205 Temperature control signal interface of the reaction disk

J 206 Reagent preheating signal interface

J 207 Interface of the power drive board

 4.9 Power Supply Assembly

The power supply assembly consists of three boards: PFC board, 24V board,
12V&5V board and ISE (optional) power supply board.

The functions of the PFC board include:

 AC/DC conversion;
 Supplying the +390V and VDD voltage to the 24V board and the 12V&5V
board;
 Supplying stable 12V voltage for the lamp;
 Supplying control signals of the analyzing unit switch to control the C12V, 5V
and 24V outputs.

The 24V board converts the 390VDC current transmitted from the PFC board to the
separated 24VDC outputs through the forward converter

The 12V&5V board converts the 390VDC voltage from the PFC board to B12V, C12V and
5V voltages through the forward converter.

The ISE power supply board converts the 12V of the reagent refrigeration board to 24V that
provides power supply for the ISE unit (optional).

5 Maintenance and Service

WARNING:

Before disassembling or assembling the analyzing unit, ensure the POWER is placed to OFF.
The probe tip is sharp and can cause puncture wounds. To prevent injury, exercise caution
when working around the probe.

BIOHAZARD:

Wear gloves and lab coat and, if necessary, goggles. Dispose of the waste in
accordance with your local or national guidelines for biohazard waste disposal.

CAUTION:
 Please use Mindray-recommended consumables. Other consumables may decrease the
system performance

Refer to the BS-300/BS-320 Chemistry Analyzer Operation Manual for details about

 unclogging the sample probe

 unclogging the reagent probe
 replacing the sample probe
 replacing the reagent probe
 replacing the mixing bar
 replacing the plunger assembly of syringe
 replacing the lamp

5.1 Replacing Lamp

The lamp of the photometric system ages after a certain period of service. An aged lamp may
introduce extra noise to the analyzing process. Replace the lamp with a new one when the
system reminds you to do so, or the service time of the lamp has added up to 2,000 hours.

1 Place the POWER to OFF. Wait at least 15 minutes for the lamp and its housing to cool
down.

WARNING:

After working for a while, the lamp and its housing are usually hot enough to burn you. Do
not proceed with this procedure until they have cooled down

2 Loosen the retaining screw on the lamp replacement door with hands or a cross-head
screwdriver, and then remove the door

3 Unscrew the retaining nut and remove the cables

4 Remove the retaining screw on the lamp.

5 Grab the lamp by the seat and pull it out.
6 Install the new lamp in the reversed steps. Restore the lamp replacement door.

NOTE:

Do not touch the light entrance of the lamp. In case the entrance is dirty, clean it with ethanol-
soaked defatted cotton.

5.2 Replacing Light Filter Assembly

The light filter and optical assembly are fixed in the supporting sleeve. The back end is
compacted and enclosed with the photoelectric amplification board and the screen gland.
Generally, the supporting sleeve is replaced together with the filter and optical assembly.

Figure 5-1 Light filter assembly

Supporting Sleeve Gasket Filter Flat Spring Lens Gasket

Lens Seat Photoelectric Conversion Board Screw Shield Box

WARNING: Before operating, ensure to place the POWER (main switch) to OFF.
1. Unscrew (counter clockwise) the two cap screws on the screen gland whose
wavelength is to be replaced.
2. Open the cover of the A/D conversion board, and unplug the plug corresponding to
certain wavelength.
3. Take out the photoelectric conversion board and the supporting sleeve
4. Keep the photoelectric conversion board upward, and loosen the two retaining screws
on it.
5. Keep the photoelectric conversion board upward, and pull the photoelectric
amplification board out of the supporting sleeve.
6. Unpack the new supporting sleeve containing the optical assembly. Be sure to keep
the top side (where to assemble the photoelectric amplification board) of the
supporting sleeve upward.
7. Install the original photoelectric conversion board onto the new supporting sleeve, and
then fasten the two retaining screws.
8. Install the screen gland, and fasten the retaining screws.
9. Connect the photoelectric conversion board to the A/D conversion board, and
assemble the cover
WARNING:

When replacing the light filter assembly, do not touch the optical assembly in the supporting
sleeve and the photoelectric receiving tube of the photoelectric conversion board by hand. The
light filters and the photoelectric conversion boards are in one-to-one relationship. Do not
disarrange them
5.3 Replacing Optical Fiber

WARNING:

Before operating, ensure to place the POWER (main switch) to OFF

1. Unscrew the four screws on the supporting pillars of the cuvette feeder, and remove
the cuvette feeder.
2. Remove the upper cover of the analyzer.
3. Unscrew the four screws on the reaction disk cover, and open the reaction disk cover.
Attention should be paid to the power cable of the upper heater when the reaction disk
cover is being opened.
4. Take out two cuvette segments in a diagonal with the needle-nose pliers to make two
spaces for disassemble the colorimetric disk

5. Unscrew three M3 cap screws, and then disassemble the colorimetric disk.
6. Use an M3 cap screwdriver to loosen the retaining screws of the optical fibers on the
colorimetric clamp.
7. Take out the optical fibers one by one, and fix the optical components in the
colorimetric clamp by fastening the screws slightly
8. Draw out all the nine optical fibers from the reaction compartment.
9. Cut off the tape fastening the fiber bundle.
10. Loosen the M3 retaining screw (used for retaining optical fibers) on the lamp
housing, and then draw out the optical fibers.
11. Put the new optical fiber into the reaction disk from its bottom one by one, loosen the
retaining screw, insert the optical fiber to the end, and then fasten the retaining screw
12. Push in the bigger end of the fiber and press closely, and then tighten the screw.
(Please note that the bigger end of the fiber and the lamp are not retained by any
measures. If necessary, remove the light source assembly to check for proper
installation of the lens. See the figure below. )
13. Fasten the fiber with a tape as it has been fastened.
14. Put the colorimetric disk back and fix it.
15. Put the reaction disk cover back and fix it.
16. Install the cuvette feeder and fix it
CAUTION:
When replacing the optical fiber, ensure that its bending radius is no less than 20cm.
Otherwise, the optical fiber will be damaged.

5.4 Adjusting Reaction Disk, Manipulator and Feeder

NOTE:
Debug the lower arm first (The relation between the lower arm position and the
reaction cuvette position is very important.), and then the upper arm. When debugging
the lower arm, move the cuvette compartment aside.

1 Disassemble the cuvette feeder, and adjust the circular position of the reaction disk (through
the initial position transducer of the reaction disk) to the standard position (The finger of the
lower arm points to the center of the slot between reaction cuvette segments).